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Volumn 21, Issue 2, 2012, Pages 171-178

The kidney and hypertension: Novel insights from transgenic models

Author keywords

angiotensin II; hypertension; kidney; knockout; transgenic

Indexed keywords

APOCYNIN; DOPAMINE; ENDOTHELIN; MINERALOCORTICOID RECEPTOR; NITRIC OXIDE; PROTEIN SERINE THREONINE KINASE; TEMPOL;

EID: 84856815284     PISSN: 10624821     EISSN: 14736543     Source Type: Journal    
DOI: 10.1097/MNH.0b013e3283503068     Document Type: Review
Times cited : (31)

References (42)
  • 1
    • 0025667012 scopus 로고
    • The surprising kidney-fluid mechanism for pressure control: Its infinite gain!
    • Guyton AC. The surprising kidney-fluid mechanism for pressure control: Its infinite gain! Hypertension 1990; 16:725-730.
    • (1990) Hypertension , vol.16 , pp. 725-730
    • Guyton, A.C.1
  • 2
    • 0027412685 scopus 로고
    • Sodium retention and hypertension after kidney transplantation in rats
    • Graf C, Maser-Gluth C, de Muinck Keizer W, et al. Sodium retention and hypertension after kidney transplantation in rats. Hypertension 1993; 21:724-730. (Pubitemid 23120229)
    • (1993) Hypertension , vol.21 , Issue.5 , pp. 724-730
    • Graf, C.1    Maser-Gluth, C.2    De Muinck Keizer, W.3    Rettig, R.4
  • 4
    • 0026336905 scopus 로고
    • Posttransplantation hypertension in recipients of renal grafts from hypertensive donor rats
    • Rettig R, Folberth CG, Graf C, et al. Posttransplantation hypertension in recipients of renal grafts from hypertensive donor rats. Clin Invest Med 1991; 14:492-498.
    • (1991) Clin Invest Med , vol.14 , pp. 492-498
    • Rettig, R.1    Folberth, C.G.2    Graf, C.3
  • 6
    • 0035936780 scopus 로고    scopus 로고
    • Molecular mechanisms of human hypertension
    • DOI 10.1016/S0092-8674(01)00241-0
    • Lifton RP, Gharavi AG, Geller DS. Molecular mechanisms of human hypertension. Cell 2001; 104:545-556. (Pubitemid 32201949)
    • (2001) Cell , vol.104 , Issue.4 , pp. 545-556
    • Lifton, R.P.1    Gharavi, A.G.2    Geller, D.S.3
  • 7
    • 79957686108 scopus 로고    scopus 로고
    • The connexin 40 A96S mutation causes renin-dependent hypertension
    • Lubkemeier I, Machura K, Kurtz L, et al. The connexin 40 A96S mutation causes renin-dependent hypertension. J Am Soc Nephrol 2011; 22:1031-1040.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 1031-1040
    • Lubkemeier, I.1    Machura, K.2    Kurtz, L.3
  • 8
    • 33744803170 scopus 로고    scopus 로고
    • cGMP stimulates renin secretion in vivo by inhibiting phosphodiesterase-3
    • DOI 10.1152/ajprenal.00209.2005
    • Beierwaltes WH. cGMP stimulates renin secretion in vivo by inhibiting phosphodiesterase-3. Am J Physiol Renal Physiol 2006; 290:F1376-1381. (Pubitemid 43830762)
    • (2006) American Journal of Physiology - Renal Physiology , vol.290 , Issue.6
    • Beierwaltes, W.H.1
  • 9
    • 74049147935 scopus 로고    scopus 로고
    • The role of calcium in the regulation of renin secretion
    • Beierwaltes WH. The role of calcium in the regulation of renin secretion. Am J Physiol Renal Physiol 2010; 298:F1-F11.
    • (2010) Am J Physiol Renal Physiol , vol.298
    • Beierwaltes, W.H.1
  • 10
    • 33847013367 scopus 로고    scopus 로고
    • Adenylyl cyclase isoform v mediates renin release from juxtaglomerular cells
    • Ortiz-Capisano MC, Ortiz PA, Harding P, et al. Adenylyl cyclase isoform v mediates renin release from juxtaglomerular cells. Hypertension 2007; 49:618-624.
    • (2007) Hypertension , vol.49 , pp. 618-624
    • Ortiz-Capisano, M.C.1    Ortiz, P.A.2    Harding, P.3
  • 12
    • 77249174833 scopus 로고    scopus 로고
    • Novel mechanisms for the control of renin synthesis and release
    • Sequeira Lopez ML, Gomez RA. Novel mechanisms for the control of renin synthesis and release. Curr Hypertens Rep 2010; 12:26-32.
    • (2010) Curr Hypertens Rep , vol.12 , pp. 26-32
    • Sequeira Lopez, M.L.1    Gomez, R.A.2
  • 14
    • 34748859681 scopus 로고    scopus 로고
    • The intrarenal renin-angiotensin system: From physiology to the pathobiology of hypertension and kidney disease
    • DOI 10.1124/pr.59.3.3
    • Kobori H, Nangaku M, Navar LG, et al. The intrarenal renin-Angiotensin system: From physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev 2007; 59:251-287. (Pubitemid 47481436)
    • (2007) Pharmacological Reviews , vol.59 , Issue.3 , pp. 251-287
    • Kobori, H.1    Nangaku, M.2    Navar, L.G.3    Nishiyama, A.4
  • 15
    • 0036181980 scopus 로고    scopus 로고
    • Regulation of intrarenal angiotensin II in hypertension
    • DOI 10.1161/hy0202.103821
    • Navar LG, Harrison-Bernard LM, Nishiyama A, et al. Regulation of intrarenal angiotensin II in hypertension. Hypertension 2002; 39 (2 Pt 2):316-322. (Pubitemid 34165142)
    • (2002) Hypertension , vol.39 , pp. 316-322
    • Navar, L.G.1    Harrison-Bernard, L.M.2    Nishiyama, A.3    Kobori, H.4
  • 16
    • 79954426057 scopus 로고    scopus 로고
    • Intrarenal angiotensin II and its contribution to the genesis of chronic hypertension
    • Navar LG, Prieto MC, Satou R, et al. Intrarenal angiotensin II and its contribution to the genesis of chronic hypertension. Curr Opin Pharmacol 2011; 11:180-186.
    • (2011) Curr Opin Pharmacol , vol.11 , pp. 180-186
    • Navar, L.G.1    Prieto, M.C.2    Satou, R.3
  • 17
    • 79952340670 scopus 로고    scopus 로고
    • Intrarenal angiotensin-converting enzyme induces hypertension in response to angiotensin I infusion
    • Gonzalez-Villalobos RA, Billet S, Kim C, et al. Intrarenal angiotensin-converting enzyme induces hypertension in response to angiotensin I infusion. J Am Soc Nephrol 2011; 22:449-459.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 449-459
    • Gonzalez-Villalobos, R.A.1    Billet, S.2    Kim, C.3
  • 18
    • 0025488224 scopus 로고
    • Angiotensin stimulates glucose and fluid absorption by rat proximal straight tubules
    • Garvin JL. Angiotensin stimulates glucose and fluid absorption by rat proximal straight tubules. J Am Soc Nephrol 1990; 1:272-277.
    • (1990) J Am Soc Nephrol , vol.1 , pp. 272-277
    • Garvin, J.L.1
  • 19
    • 0026135277 scopus 로고
    • Angiotensin stimulates bicarbonate transport and Na+/K+ ATPase in rat proximal straight tubules
    • Garvin JL. Angiotensin stimulates bicarbonate transport and Na+/K+ ATPase in rat proximal straight tubules. J Am Soc Nephrol 1991; 1:1146-1152.
    • (1991) J Am Soc Nephrol , vol.1 , pp. 1146-1152
    • Garvin, J.L.1
  • 20
    • 0022495441 scopus 로고
    • Control of sodium excretion by angiotensin II: Intrarenal mechanisms and blood pressure regulation
    • Hall JE. Control of sodium excretion by angiotensin II: Intrarenal mechanisms and blood pressure regulation. Am J Physiol 1986; 250:R960-972.
    • (1986) Am J Physiol , vol.250
    • Hall, J.E.1
  • 21
    • 0017349968 scopus 로고
    • Dose dependent stimulation and inhibition of proximal tubular sodium reabsorption by angiotensin II in the rat kidney
    • DOI 10.1007/BF00581370
    • Harris PJ, Young JA. Dose-dependent stimulation and inhibition of proximal tubular sodium reabsorption by angiotensin II in the rat kidney. Pflugers Arch 1977; 367:295-297. (Pubitemid 8014493)
    • (1977) Pflugers Archiv European Journal of Physiology , vol.367 , Issue.3 , pp. 295-297
    • Harris, P.J.1    Young, J.A.2
  • 23
    • 80055099871 scopus 로고    scopus 로고
    • The role of AT1 receptor-mediated salt retention in angiotensin II-dependent hypertension
    • Crowley SD, Zhang J, Herrera M, et al. The role of AT1 receptor-mediated salt retention in angiotensin II-dependent hypertension. Am J Physiol Renal Physiol 2011; 301:F1124-F1130.
    • (2011) Am J Physiol Renal Physiol , vol.301
    • Crowley, S.D.1    Zhang, J.2    Herrera, M.3
  • 24
    • 79953743181 scopus 로고    scopus 로고
    • AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure
    • This article highlights the importance of AT1 receptors in the proximal tubule of the kidney in blood pressure homeostasis
    • Gurley SB, Riquier-Brison AD, Schnermann J, et al. AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure. Cell Metab 2011; 13:469-475. This article highlights the importance of AT1 receptors in the proximal tubule of the kidney in blood pressure homeostasis.
    • (2011) Cell Metab , vol.13 , pp. 469-475
    • Gurley, S.B.1    Riquier-Brison, A.D.2    Schnermann, J.3
  • 25
    • 80053655134 scopus 로고    scopus 로고
    • Renal proximal tubule angiotensin AT1A receptors regulate blood pressure
    • This article highlights the importance of AT1 receptors in the proximal tubule of the kidney in blood pressure homeostasis
    • Li H, Weatherford ET, Davis DR, et al. Renal proximal tubule angiotensin AT1A receptors regulate blood pressure. Am J Physiol Regul Integr Comp Physiol 2011; 301:R1067-R1077. This article highlights the importance of AT1 receptors in the proximal tubule of the kidney in blood pressure homeostasis.
    • (2011) Am J Physiol Regul Integr Comp Physiol , vol.301
    • Li, H.1    Weatherford, E.T.2    Davis, D.R.3
  • 26
    • 57349168398 scopus 로고    scopus 로고
    • Modification of mineralocorticoid receptor function by Rac1 GTPase: Implication in proteinuric kidney disease
    • Shibata S, Nagase M, Yoshida S, et al. Modification of mineralocorticoid receptor function by Rac1 GTPase: Implication in proteinuric kidney disease. Nat Med 2008; 14:1370-1376.
    • (2008) Nat Med , vol.14 , pp. 1370-1376
    • Shibata, S.1    Nagase, M.2    Yoshida, S.3
  • 27
    • 79960972766 scopus 로고    scopus 로고
    • Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptordependent pathway
    • This article demonstrated that over-Activation of Rac1 causes hypertension by augmenting activity of the mineralocorticoid receptor
    • Shibata S, Mu S, Kawarazaki H, et al. Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptordependent pathway. J Clin Invest 2011; 121:3233-3243. This article demonstrated that over-Activation of Rac1 causes hypertension by augmenting activity of the mineralocorticoid receptor.
    • (2011) J Clin Invest , vol.121 , pp. 3233-3243
    • Shibata, S.1    Mu, S.2    Kawarazaki, H.3
  • 29
    • 80052705787 scopus 로고    scopus 로고
    • A SPAK isoform switch modulates renal salt transport and blood pressure
    • This article shows that SPAK kinases diferentially regulate sodium transport in the distal nephron impacting blood pressure
    • McCormick JA, Mutig K, Nelson JH, et al. A SPAK isoform switch modulates renal salt transport and blood pressure. Cell Metab 2011; 14:352-364. This article shows that SPAK kinases diferentially regulate sodium transport in the distal nephron impacting blood pressure.
    • (2011) Cell Metab , vol.14 , pp. 352-364
    • McCormick, J.A.1    Mutig, K.2    Nelson, J.H.3
  • 30
    • 11144257719 scopus 로고    scopus 로고
    • A high-salt diet stimulates thick ascending limb eNOS expression by raising medullary osmolality and increasing release of endothelin-1
    • DOI 10.1152/ajprenal.00209.2004
    • Herrera M, Garvin JL. A high-salt diet stimulates thick ascending limb eNOS expression by raising medullary osmolality and increasing release of endothelin-1. Am J Physiol Renal Physiol 2005; 288:F58-64. (Pubitemid 40038676)
    • (2005) American Journal of Physiology - Renal Physiology , vol.288
    • Herrera, M.1    Garvin, J.L.2
  • 33
    • 57349141943 scopus 로고    scopus 로고
    • Combined knockout of collecting duct endothelin A and B receptors causes hypertension and sodium retention
    • Ge Y, Bagnall A, Stricklett PK, et al. Combined knockout of collecting duct endothelin A and B receptors causes hypertension and sodium retention. Am J Physiol Renal Physiol 2008; 295:F1635-1640.
    • (2008) Am J Physiol Renal Physiol , vol.295
    • Ge, Y.1    Bagnall, A.2    Stricklett, P.K.3
  • 34
    • 83455176264 scopus 로고    scopus 로고
    • Collecting duct-specific endothelin B receptor knockout increases ENaC activity
    • These studies showed that ETB receptor activation inhibits ENaC open probability in the collecting duct, promoting natriuresis during high salt intake
    • Bugaj V, Mironova E, Kohan DE, et al. Collecting duct-specific endothelin B receptor knockout increases ENaC activity. Am J Physiol Cell Physiol 2011; 302:C188-C194. These studies showed that ETB receptor activation inhibits ENaC open probability in the collecting duct, promoting natriuresis during high salt intake.
    • (2011) Am J Physiol Cell Physiol , vol.302
    • Bugaj, V.1    Mironova, E.2    Kohan, D.E.3
  • 35
    • 84926134228 scopus 로고    scopus 로고
    • Regulation of sodium transport in the proximal tubule by endothelin
    • Zhang Y, Jose PA, Zeng C. Regulation of sodium transport in the proximal tubule by endothelin. Contrib Nephrol 2011; 172:63-75.
    • (2011) Contrib Nephrol , vol.172 , pp. 63-75
    • Zhang, Y.1    Jose, P.A.2    Zeng, C.3
  • 36
    • 59449083744 scopus 로고    scopus 로고
    • Endothelin-1 inhibits thick ascending limb transport via Akt-stimulated nitric oxide production
    • Herrera M, Hong NJ, Ortiz PA, et al. Endothelin-1 inhibits thick ascending limb transport via Akt-stimulated nitric oxide production. J Biol Chem 2009; 284:1454-1460.
    • (2009) J Biol Chem , vol.284 , pp. 1454-1460
    • Herrera, M.1    Hong, N.J.2    Ortiz, P.A.3
  • 37
    • 84926108190 scopus 로고    scopus 로고
    • Role of endothelin in thick ascending limb sodium chloride transport
    • Ramseyer VD, Cabral PD, Garvin JL. Role of endothelin in thick ascending limb sodium chloride transport. Contrib Nephrol 2011; 172:76-83.
    • (2011) Contrib Nephrol , vol.172 , pp. 76-83
    • Ramseyer, V.D.1    Cabral, P.D.2    Garvin, J.L.3
  • 38
    • 77956480688 scopus 로고    scopus 로고
    • High-salt intake enhances superoxide activity in eNOS knockout mice leading to the development of salt sensitivity
    • This article highlights the importance of nitric oxide derived from eNOS in preventing salt-sensitive hypertension via its actions within the kidney
    • Kopkan L, Hess A, Huskova Z, et al. High-salt intake enhances superoxide activity in eNOS knockout mice leading to the development of salt sensitivity. Am J Physiol Renal Physiol 2010; 299:F656-663. This article highlights the importance of nitric oxide derived from eNOS in preventing salt-sensitive hypertension via its actions within the kidney.
    • (2010) Am J Physiol Renal Physiol , vol.299
    • Kopkan, L.1    Hess, A.2    Huskova, Z.3
  • 39
    • 77949850439 scopus 로고    scopus 로고
    • Nitric oxide produced by endothelial nitric oxide synthase promotes diuresis
    • This study demonstrated the importance of nitric oxide derived from eNOS to promote natriuresis by inhibiting NKCC2 in the thick ascending limb
    • Perez-Rojas JM, Kassem KM, Beierwaltes WH, et al. Nitric oxide produced by endothelial nitric oxide synthase promotes diuresis. Am J Physiol Regul Integr Comp Physiol 2010; 298:R1050-1055. This study demonstrated the importance of nitric oxide derived from eNOS to promote natriuresis by inhibiting NKCC2 in the thick ascending limb.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.298
    • Perez-Rojas, J.M.1    Kassem, K.M.2    Beierwaltes, W.H.3
  • 40
    • 33644547657 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms for diagnosis of salt-sensitive hypertension
    • Sanada H, Yatabe J, Midorikawa S, et al. Single-nucleotide polymorphisms for diagnosis of salt-sensitive hypertension. Clin Chem 2006; 52:352-360.
    • (2006) Clin Chem , vol.52 , pp. 352-360
    • Sanada, H.1    Yatabe, J.2    Midorikawa, S.3
  • 41
    • 79959982558 scopus 로고    scopus 로고
    • Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice
    • This article highlights the importance of dopamine synthesized in the renal proximal tubule as an antinatriuretic factor controling blood pressure homeostasis
    • Zhang MZ, Yao B, Wang S, et al. Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice. J Clin Invest 2011; 121: 2845-2854. This article highlights the importance of dopamine synthesized in the renal proximal tubule as an antinatriuretic factor controling blood pressure homeostasis.
    • (2011) J Clin Invest , vol.121 , pp. 2845-2854
    • Zhang, M.Z.1    Yao, B.2    Wang, S.3


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