Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention

Journal of Clinical Investigation

Volumn 114, Issue 4, 2004, Pages 504-511

  Ahn, Dowhan ^a,b   Ge, Yuqiang ^a   Stricklett, Peter K ^a   Gill, Pritmohinder ^a   Taylor, Deborah ^a   Hughes, Alisa K ^a   Yanagisawa, Masashi ^c   Miller, Lance ^a   Nelson, Raoul D ^a   Kohan, Donald E ^a,d  

^a UNIVERSITY OF UTAH   (United States)

^b Kosin University   (South Korea)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; AMILORIDE; ENDOTHELIN 1; FUROSEMIDE; MESSENGER RNA; DIURETIC AGENT;

ALDOSTERONE URINE LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ESSENTIAL HYPERTENSION; FEMALE; HETEROZYGOSITY; HIGH SODIUM INTAKE; KIDNEY COLLECTING TUBULE; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROTEIN URINE LEVEL; SODIUM RETENTION; URINARY EXCRETION; WEIGHT GAIN; ANIMAL; BLOOD PRESSURE; C57BL MOUSE; DRUG EFFECT; GENETICS; HETEROZYGOTE; HOMOZYGOTE; HYPERNATREMIA; HYPERTENSION; IN SITU HYBRIDIZATION; MOUSE MUTANT; PHYSIOLOGY; SALT INTAKE; TRANSGENIC MOUSE; URINE;

ALDOSTERONE; AMILORIDE; ANIMALS; BLOOD PRESSURE; DIURETICS; ENDOTHELIN-1; FUROSEMIDE; HETEROZYGOTE; HOMOZYGOTE; HYPERNATREMIA; HYPERTENSION; IN SITU HYBRIDIZATION; KIDNEY TUBULES, COLLECTING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; RNA, MESSENGER; SODIUM CHLORIDE, DIETARY; WEIGHT GAIN;

EID: 4344622740     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200421064     Document Type: Article

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