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Volumn 12, Issue 1, 2010, Pages 26-32

Novel mechanisms for the control of renin synthesis and release

Author keywords

CAMP; Cell identity; Homeostasis; Juxtaglomerular cells; MicroRNAs; Plasticity

Indexed keywords

ANGIOTENSIN; CALCIUM; CYCLIC AMP; DICER; HISTONE ACETYLTRANSFERASE; MICRORNA; RENIN; UNTRANSLATED RNA;

EID: 77249174833     PISSN: 15226417     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11906-009-0080-z     Document Type: Review
Times cited : (32)

References (42)
  • 1
    • 2342512100 scopus 로고    scopus 로고
    • Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened
    • Sequeira Lopez ML, Pentz ES, Nomasa T, et al.: Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened. Dev Cell 2004, 6:719-728.
    • (2004) Dev Cell , vol.6 , pp. 719-728
    • Sequeira Lopez, M.L.1    Pentz, E.S.2    Nomasa, T.3
  • 2
    • 0025027754 scopus 로고
    • Recruitment of renin gene-expressing cells in adult rat kidneys
    • 1:CAS:528:DyaK3cXmt1Gisbs%3D 2221104
    • RA Gomez RL Chevalier AD Everett, et al. 1990 Recruitment of renin gene-expressing cells in adult rat kidneys Am J Physiol 259 F660 F665 1:CAS:528:DyaK3cXmt1Gisbs%3D 2221104
    • (1990) Am J Physiol , vol.259
    • Gomez, R.A.1    Chevalier, R.L.2    Everett, A.D.3
  • 3
    • 0037123931 scopus 로고    scopus 로고
    • Control of renin secretion from rat juxtaglomerular cells by cAMP-specific phosphodiesterases
    • DOI 10.1161/01.RES.0000017622.25365.71
    • UG Friis BL Jensen S Sethi, et al. 2002 Control of renin secretion from rat juxtaglomerular cells by cAMP-specific phosphodiesterases Circ Res 90 996 1003 10.1161/01.RES.0000017622.25365.71 1:CAS:528:DC%2BD38XjvFGksLc%3D 12016266 (Pubitemid 34633866)
    • (2002) Circulation Research , vol.90 , Issue.9 , pp. 996-1003
    • Friis, U.G.1    Jensen, B.L.2    Sethi, S.3    Andreasen, D.4    Hansen, P.B.5    Skott, O.6
  • 5
    • 0033000013 scopus 로고    scopus 로고
    • Human renin mRNA stability is increased in response to cAMP in Calu-6 cells
    • 10082506
    • PL Sinn CD Sigmund 1999 Human renin mRNA stability is increased in response to cAMP in Calu-6 cells Hypertension 33 900 905 10082506
    • (1999) Hypertension , vol.33 , pp. 900-905
    • Sinn, P.L.1    Sigmund, C.D.2
  • 6
    • 0025368608 scopus 로고
    • Renin release and gene expression in intact rat kidney microvessels and single cells
    • 10.1172/JCI114680 1:CAS:528:DyaK3cXkvFWqt7s%3D 2164041
    • AD Everett RM Carey RL Chevalier, et al. 1990 Renin release and gene expression in intact rat kidney microvessels and single cells J Clin Invest 86 169 175 10.1172/JCI114680 1:CAS:528:DyaK3cXkvFWqt7s%3D 2164041
    • (1990) J Clin Invest , vol.86 , pp. 169-175
    • Everett, A.D.1    Carey, R.M.2    Chevalier, R.L.3
  • 7
    • 0019931417 scopus 로고
    • Forskolin stimulates renin release from the isolated perfused rat kidney
    • 10.1016/0014-2999(82)90165-0 1:CAS:528:DyaL3sXjt1U%3D 6128235
    • U Schwertschlag E Hackenthal 1982 Forskolin stimulates renin release from the isolated perfused rat kidney Eur J Pharmacol 84 111 113 10.1016/0014-2999(82)90165-0 1:CAS:528:DyaL3sXjt1U%3D 6128235
    • (1982) Eur J Pharmacol , vol.84 , pp. 111-113
    • Schwertschlag, U.1    Hackenthal, E.2
  • 8
    • 39149126353 scopus 로고    scopus 로고
    • Identity of the renin cell is mediated by cAMP and chromatin remodeling: An in vitro model for studying cell recruitment and plasticity
    • DOI 10.1152/ajpheart.01152.2007
    • ES Pentz ML Lopez M Cordaillat, et al. 2008 Identity of the renin cell is mediated by cAMP and chromatin remodeling: an in vitro model for studying cell recruitment and plasticity Am J Physiol Heart Circ Physiol 294 H699 H707 10.1152/ajpheart.01152.2007 1:CAS:528:DC%2BD1cXit1yls7g%3D 18055510 Using mice in which renin-expressing cells are dually labeled with fluorescent proteins (CFP as a lineage marker and YFP as an active transcription of renin marker), the authors developed an in vitro cell culture system that can be maintained after multiple passages and that responds to cAMP stimulation with renin expression. Furthermore, they identified acetylated histone 4 as a key epigenetic marker at the CRE of the renin promoter (Pubitemid 351253281)
    • (2008) American Journal of Physiology - Heart and Circulatory Physiology , vol.294 , Issue.2
    • Pentz, E.S.1    Sequeira Lopez, M.L.S.2    Cordaillat, M.3    Gomez, R.A.4
  • 9
    • 66149147354 scopus 로고    scopus 로고
    • CBP and p300 are essential for renin cell identity and morphological integrity of the kidney
    • 10.1152/ajpheart.01266.2008 1:CAS:528:DC%2BD1MXlvFagtbY%3D 19252086 Using mice with conditional deletion of the HATs CBP and/or p300 in renin-expressing cells, the authors showed that individual deletion of either CBP or p300 did not affect renin expression, but the combined deletion resulted in lack of renin cells and kidney abnormalities
    • RA Gomez ES Pentz X Jin, et al. 2009 CBP and p300 are essential for renin cell identity and morphological integrity of the kidney Am J Physiol Heart Circ Physiol 296 H1255 H1262 10.1152/ajpheart.01266.2008 1:CAS:528: DC%2BD1MXlvFagtbY%3D 19252086 Using mice with conditional deletion of the HATs CBP and/or p300 in renin-expressing cells, the authors showed that individual deletion of either CBP or p300 did not affect renin expression, but the combined deletion resulted in lack of renin cells and kidney abnormalities
    • (2009) Am J Physiol Heart Circ Physiol , vol.296
    • Gomez, R.A.1    Pentz, E.S.2    Jin, X.3
  • 10
    • 34250838128 scopus 로고    scopus 로고
    • Regulation of renin secretion and expression in mice deficient in β1- and β2-adrenergic receptors
    • DOI 10.1161/HYPERTENSIONAHA.107.087577, PII 0000426820070700000019
    • SM Kim L Chen R Faulhaber-Walter, et al. 2007 Regulation of renin secretion and expression in mice deficient in beta1- and beta2-adrenergic receptors Hypertension 50 103 109 10.1161/HYPERTENSIONAHA.107.087577 1:CAS:528:DC%2BD2sXmtlKqsL4%3D 17515456 (Pubitemid 46986017)
    • (2007) Hypertension , vol.50 , Issue.1 , pp. 103-109
    • Kim, S.M.1    Chen, L.2    Faulhaber-Walter, R.3    Oppermann, M.4    Huang, Y.5    Mizel, D.6    Briggs, J.P.7    Schnermann, J.8
  • 12
    • 66049146531 scopus 로고    scopus 로고
    • Development of vascular renin expression in the kidney critically depends on the cyclic AMP pathway
    • 10.1152/ajprenal.90448.2008 1:CAS:528:DC%2BD1MXlvFantbk%3D 19261741
    • B Neubauer K Machura M Chen, et al. 2009 Development of vascular renin expression in the kidney critically depends on the cyclic AMP pathway Am J Physiol Renal Physiol 296 F1006 F1012 10.1152/ajprenal.90448.2008 1:CAS:528:DC%2BD1MXlvFantbk%3D 19261741
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Neubauer, B.1    MacHura, K.2    Chen, M.3
  • 13
    • 0030726185 scopus 로고    scopus 로고
    • Zis: A developmentally regulated gene expressed in juxtaglomerular cells
    • 1:CAS:528:DyaK2sXnsVCqtr0%3D 9374836
    • EA Karginova ES Pentz IG Kazakova, et al. 1997 Zis: a developmentally regulated gene expressed in juxtaglomerular cells Am J Physiol 273 F731 F738 1:CAS:528:DyaK2sXnsVCqtr0%3D 9374836
    • (1997) Am J Physiol , vol.273
    • Karginova, E.A.1    Pentz, E.S.2    Kazakova, I.G.3
  • 14
    • 0025201726 scopus 로고
    • Isolation and characterization of renin-expressing cell lines from transgenic mice containing a renin-promoter viral oncogene fusion construct
    • 1:CAS:528:DyaK3cXlvVyltL0%3D 2174057
    • CD Sigmund K Okuyama J Ingelfinger, et al. 1990 Isolation and characterization of renin-expressing cell lines from transgenic mice containing a renin-promoter viral oncogene fusion construct J Biol Chem 265 19916 19922 1:CAS:528:DyaK3cXlvVyltL0%3D 2174057
    • (1990) J Biol Chem , vol.265 , pp. 19916-19922
    • Sigmund, C.D.1    Okuyama, K.2    Ingelfinger, J.3
  • 15
    • 11244309604 scopus 로고    scopus 로고
    • Transcriptional regulation of renin: An update
    • 10.1161/01.HYP.0000151886.26341.4b 1:CAS:528:DC%2BD2cXhtFaiu7zK 15545507
    • L Pan KW Gross 2005 Transcriptional regulation of renin: an update Hypertension 45 3 8 10.1161/01.HYP.0000151886.26341.4b 1:CAS:528: DC%2BD2cXhtFaiu7zK 15545507
    • (2005) Hypertension , vol.45 , pp. 3-8
    • Pan, L.1    Gross, K.W.2
  • 16
    • 34548577119 scopus 로고    scopus 로고
    • Dissecting the action of an evolutionary conserved non-coding region on renin promoter activity
    • DOI 10.1093/nar/gkm535
    • R Mrowka A Steege C Kaps, et al. 2007 Dissecting the action of an evolutionary conserved non-coding region on renin promoter activity Nucleic Acids Res 35 5120 5129 10.1093/nar/gkm535 1:CAS:528:DC%2BD2sXpvFWgsbo%3D 17660193 (Pubitemid 47394196)
    • (2007) Nucleic Acids Research , vol.35 , Issue.15 , pp. 5120-5129
    • Mrowka, R.1    Steege, A.2    Kaps, C.3    Herzel, H.4    Thiele, B.J.5    Persson, P.B.6    Bluthgen, N.7
  • 17
    • 0035793588 scopus 로고    scopus 로고
    • Retinoic acid-mediated activation of the mouse renin enhancer
    • 10.1074/jbc.M008361200 1:CAS:528:DC%2BD3MXhtFWisb8%3D 11058598
    • Q Shi KW Gross CD Sigmund 2001 Retinoic acid-mediated activation of the mouse renin enhancer J Biol Chem 276 3597 3603 10.1074/jbc.M008361200 1:CAS:528:DC%2BD3MXhtFWisb8%3D 11058598
    • (2001) J Biol Chem , vol.276 , pp. 3597-3603
    • Shi, Q.1    Gross, K.W.2    Sigmund, C.D.3
  • 18
    • 0036073755 scopus 로고    scopus 로고
    • 1, 25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system
    • 1:CAS:528:DC%2BD38XlsVGlsbg%3D 12122115
    • YC Li J Kong M Wei, et al. 2002 1, 25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system J Clin Invest 110 229 238 1:CAS:528:DC%2BD38XlsVGlsbg%3D 12122115
    • (2002) J Clin Invest , vol.110 , pp. 229-238
    • Li, Y.C.1    Kong, J.2    Wei, M.3
  • 19
    • 35848935619 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ is involved in the control of renin gene expression
    • DOI 10.1161/HYPERTENSIONAHA.107.092817, PII 0000426820071100000022
    • VT Todorov M Desch N Schmitt-Nilson, et al. 2007 Peroxisome proliferator-activated receptor-gamma is involved in the control of renin gene expression Hypertension 50 939 944 10.1161/HYPERTENSIONAHA.107.092817 1:CAS:528:DC%2BD2sXhtFGjtbbF 17785633 (Pubitemid 350287538)
    • (2007) Hypertension , vol.50 , Issue.5 , pp. 939-944
    • Todorov, V.T.1    Desch, M.2    Schmitt-Nilson, N.3    Todorova, A.4    Kurtz, A.5
  • 20
    • 50449108231 scopus 로고    scopus 로고
    • The Pal3 promoter sequence is critical for the regulation of human renin gene transcription by peroxisome proliferator-activated receptor-gamma
    • 10.1210/en.2008-0127 1:CAS:528:DC%2BD1cXhtVKnu7bK 18483152
    • VT Todorov M Desch T Schubert, et al. 2008 The Pal3 promoter sequence is critical for the regulation of human renin gene transcription by peroxisome proliferator-activated receptor-gamma Endocrinology 149 4647 4657 10.1210/en.2008-0127 1:CAS:528:DC%2BD1cXhtVKnu7bK 18483152
    • (2008) Endocrinology , vol.149 , pp. 4647-4657
    • Todorov, V.T.1    Desch, M.2    Schubert, T.3
  • 21
    • 35348960363 scopus 로고    scopus 로고
    • Renin release
    • 1:CAS:528:DC%2BD2sXhtlelsbnN This is an outstanding detailed review on renin release
    • F Schweda U Friis C Wagner, et al. 2007 Renin release Physiology (Bethesda) 22 310 319 1:CAS:528:DC%2BD2sXhtlelsbnN This is an outstanding detailed review on renin release
    • (2007) Physiology (Bethesda) , vol.22 , pp. 310-319
    • Schweda, F.1    Friis, U.2    Wagner, C.3
  • 22
    • 74049147935 scopus 로고    scopus 로고
    • The role of calcium in the regulation of renin secretion
    • This excellent review summarizes current knowledge about the role of calcium in renin secretion
    • •• Beierwaltes WH: The role of calcium in the regulation of renin secretion. Am J Physiol Renal Physiol 2009 July 29 (Epub ahead of print). This excellent review summarizes current knowledge about the role of calcium in renin secretion.
    • Am J Physiol Renal Physiol 2009 July 29 (Epub Ahead of Print)
    • Beierwaltes, W.H.1
  • 23
    • 34548863136 scopus 로고    scopus 로고
    • Expression and function of the calcium-sensing receptor in juxtaglomerular cells
    • DOI 10.1161/HYPERTENSIONAHA.107.095158, PII 0000426820071000000027
    • MC Ortiz-Capisano PA Ortiz JL Garvin, et al. 2007 Expression and function of the calcium-sensing receptor in juxtaglomerular cells Hypertension 50 737 743 10.1161/HYPERTENSIONAHA.107.095158 1:CAS:528:DC%2BD2sXhtVCrtLzP 17785631 (Pubitemid 47442739)
    • (2007) Hypertension , vol.50 , Issue.4 , pp. 737-743
    • Ortiz-Capisano, M.C.1    Ortiz, P.A.2    Garvin, J.L.3    Harding, P.4    Beierwaltes, W.H.5
  • 24
    • 33751335626 scopus 로고    scopus 로고
    • The calcium paradoxon of renin release: Calcium suppresses renin exocytosis by inhibition of calcium-dependent adenylate cyclases AC5 and AC6
    • DOI 10.1161/01.RES.0000251057.35537.d3, PII 0000301220061124000009
    • C Grunberger B Obermayer J Klar, et al. 2006 The calcium paradoxon of renin release: calcium suppresses renin exocytosis by inhibition of calcium-dependent adenylate cyclases AC5 and AC6 Circ Res 99 1197 1206 10.1161/01.RES.0000251057.35537.d3 17068292 (Pubitemid 44808656)
    • (2006) Circulation Research , vol.99 , Issue.11 , pp. 1197-1206
    • Grunberger, C.1    Obermayer, B.2    Klar, J.3    Kurtz, A.4    Schweda, F.5
  • 25
    • 33847043743 scopus 로고    scopus 로고
    • Decreased intracellular calcium stimulates renin release via calcium-inhibitable adenylyl cyclase
    • DOI 10.1161/01.HYP.0000250708.04205.d4, PII 0000426820070100000031
    • MC Ortiz-Capisano PA Ortiz P Harding, et al. 2007 Decreased intracellular calcium stimulates renin release via calcium-inhibitable adenylyl cyclase Hypertension 49 162 169 10.1161/01.HYP.0000250708.04205.d4 1:CAS:528: DC%2BD28XhtlSrs7vL 17088449 (Pubitemid 46360356)
    • (2007) Hypertension , vol.49 , Issue.1 , pp. 162-169
    • Ortiz-Capisano, M.C.1    Ortiz, P.A.2    Harding, P.3    Garvin, J.L.4    Beierwaltes, W.H.5
  • 26
    • 70449686368 scopus 로고    scopus 로고
    • Calcium-dependent phosphodiesterase 1C inhibits renin release from isolated juxtaglomerular cells
    • 1:CAS:528:DC%2BD1MXhsValtr7K 19741056
    • MC Ortiz-Capisano TD Liao PA Ortiz WH Beierwaltes 2009 Calcium-dependent phosphodiesterase 1C inhibits renin release from isolated juxtaglomerular cells Am J Physiol Regul Integr Comp Physiol 297 5 R1469 R1476 1:CAS:528: DC%2BD1MXhsValtr7K 19741056
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.297 , Issue.5
    • Ortiz-Capisano, M.C.1    Liao, T.D.2    Ortiz, P.A.3    Beierwaltes, W.H.4
  • 27
    • 0037331196 scopus 로고    scopus 로고
    • Implication of Ref-1 in the repression of renin gene transcription by intracellular calcium
    • DOI 10.1097/00004872-200302000-00024
    • S Fuchs J Philippe P Corvol F Pinet 2003 Implication of Ref-1 in the repression of renin gene transcription by intracellular calcium J Hypertens 21 327 335 10.1097/00004872-200302000-00024 1:CAS:528:DC%2BD3sXptFOjtw%3D%3D 12569263 (Pubitemid 36269704)
    • (2003) Journal of Hypertension , vol.21 , Issue.2 , pp. 327-335
    • Fuchs, S.1    Philippe, J.2    Corvol, P.3    Pinet, F.4
  • 28
    • 31944449745 scopus 로고    scopus 로고
    • Calcium inhibits renin gene expression by transcriptional and posttranscriptional mechanisms
    • 10.1161/01.HYP.0000192025.86189.46 1:CAS:528:DC%2BD2MXht1arsrjN 16286572
    • J Klar M Sigl B Obermayer, et al. 2005 Calcium inhibits renin gene expression by transcriptional and posttranscriptional mechanisms Hypertension 46 1340 1346 10.1161/01.HYP.0000192025.86189.46 1:CAS:528:DC%2BD2MXht1arsrjN 16286572
    • (2005) Hypertension , vol.46 , pp. 1340-1346
    • Klar, J.1    Sigl, M.2    Obermayer, B.3
  • 29
    • 0037423817 scopus 로고    scopus 로고
    • Posttranscriptional control of renin synthesis: Identification of proteins interacting with renin mRNA 3′-untranslated region
    • DOI 10.1161/01.RES.0000059300.67152.4E
    • A Skalweit A Doller A Huth, et al. 2003 Posttranscriptional control of renin synthesis: identification of proteins interacting with renin mRNA 3'-untranslated region Circ Res 92 419 427 10.1161/01.RES.0000059300.67152.4E 1:CAS:528:DC%2BD3sXhsValtbo%3D 12600897 (Pubitemid 36298202)
    • (2003) Circulation Research , vol.92 , Issue.4 , pp. 419-427
    • Skalweit, A.1    Doller, A.2    Huth, A.3    Kahne, T.4    Persson, P.B.5    Thiele, B.-J.6
  • 30
    • 39349113778 scopus 로고    scopus 로고
    • Function of connexins in the renal circulation
    • DOI 10.1038/sj.ki.5002720, PII 5002720
    • C Wagner 2008 Function of connexins in the renal circulation Kidney Int 73 547 555 10.1038/sj.ki.5002720 1:CAS:528:DC%2BD1cXhvFCmsLc%3D 18075497 (Pubitemid 351264110)
    • (2008) Kidney International , vol.73 , Issue.5 , pp. 547-555
    • Wagner, C.1
  • 33
    • 33947514231 scopus 로고    scopus 로고
    • Connexin40 is essential for the pressure control of renin synthesis and secretion
    • DOI 10.1161/01.RES.0000258856.19922.45, PII 0000301220070302000015
    • C Wagner C de Wit L Kurtz, et al. 2007 Connexin40 is essential for the pressure control of renin synthesis and secretion Circ Res 100 556 563 10.1161/01.RES.0000258856.19922.45 1:CAS:528:DC%2BD2sXitFylsbk%3D 17255527 The authors show that in mice with deletion of connexin 40, the negative control of renin secretion and synthesis by angiotensin II and by intravascular pressure is abrogated (Pubitemid 46673265)
    • (2007) Circulation Research , vol.100 , Issue.4 , pp. 556-563
    • Wagner, C.1    De Wit, C.2    Kurtz, L.3    Grunberger, C.4    Kurtz, A.5    Schweda, F.6
  • 34
    • 60749131296 scopus 로고    scopus 로고
    • Substitution of connexin40 with connexin45 prevents hyperreninemia and attenuates hypertension
    • 10.1038/ki.2008.637 1:CAS:528:DC%2BD1MXit1Wnsbo%3D 19109587
    • F Schweda L Kurtz C de Wit, et al. 2009 Substitution of connexin40 with connexin45 prevents hyperreninemia and attenuates hypertension Kidney Int 75 482 489 10.1038/ki.2008.637 1:CAS:528:DC%2BD1MXit1Wnsbo%3D 19109587
    • (2009) Kidney Int , vol.75 , pp. 482-489
    • Schweda, F.1    Kurtz, L.2    De Wit, C.3
  • 35
    • 0000906892 scopus 로고
    • The effect of high perfusion pressures on the granulation of juxtaglomerular cells in an isolated kidney
    • 10.1172/JCI103838 1:STN:280:DyaG1M%2FntFSitA%3D%3D 13641411
    • L Tobian A Tomboulian J Janecek 1959 The effect of high perfusion pressures on the granulation of juxtaglomerular cells in an isolated kidney J Clin Invest 38 605 610 10.1172/JCI103838 1:STN:280:DyaG1M%2FntFSitA%3D%3D 13641411
    • (1959) J Clin Invest , vol.38 , pp. 605-610
    • Tobian, L.1    Tomboulian, A.2    Janecek, J.3
  • 36
    • 60749107460 scopus 로고    scopus 로고
    • Sequeira Lopez ML: Who and where is the renal baroreceptor?: The connexin hypothesis
    • 10.1038/ki.2008.536 1:CAS:528:DC%2BD1MXit1Wntr0%3D 19219002
    • RA Gomez 2009 Sequeira Lopez ML: Who and where is the renal baroreceptor?: the connexin hypothesis Kidney Int 75 460 462 10.1038/ki.2008.536 1:CAS:528:DC%2BD1MXit1Wntr0%3D 19219002
    • (2009) Kidney Int , vol.75 , pp. 460-462
    • Gomez, R.A.1
  • 37
    • 33747123710 scopus 로고    scopus 로고
    • MicroRNAs and cell differentiation in mammalian development
    • DOI 10.1002/bdrc.20070
    • L Song RS Tuan 2006 MicroRNAs and cell differentiation in mammalian development Birth Defects Res C Embryo Today 78 140 149 10.1002/bdrc.20070 1:CAS:528:DC%2BD28XotleitbY%3D 16847891 (Pubitemid 44222853)
    • (2006) Birth Defects Research Part C - Embryo Today: Reviews , vol.78 , Issue.2 , pp. 140-149
    • Song, L.1    Tuan, R.S.2
  • 38
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • DOI 10.1016/S0092-8674(04)00045-5
    • DP Bartel 2004 MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 281 297 10.1016/S0092-8674(04)00045-5 1:CAS:528:DC%2BD2cXhtVals7o%3D 14744438 (Pubitemid 38167318)
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 39
    • 39749110083 scopus 로고    scopus 로고
    • Small non-coding RNAs in animal development
    • DOI 10.1038/nrm2347, PII NRM2347
    • G Stefani FJ Slack 2008 Small non-coding RNAs in animal development Nat Rev Mol Cell Biol 9 219 230 10.1038/nrm2347 1:CAS:528:DC%2BD1cXitlGnurY%3D 18270516 (Pubitemid 351301826)
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.3 , pp. 219-230
    • Stefani, G.1    Slack, F.J.2
  • 40
    • 77249090106 scopus 로고    scopus 로고
    • The microRNA processing enzyme Dicer is required for the maintenance of the renin cell phenotype in vivo [abstract P405]
    • Chicago, IL; September 23-26
    • Sequeira Lopez ML, Weatherford ET, Borges GR, et al.: The microRNA processing enzyme Dicer is required for the maintenance of the renin cell phenotype in vivo [abstract P405]. Presented at the 63rd High Blood Pressure Research Conference. Chicago, IL; September 23-26, 2009.
    • (2009) Presented at the 63rd High Blood Pressure Research Conference
    • Sequeira Lopez, M.L.1    Weatherford, E.T.2    Borges, G.R.3
  • 42
    • 40149083894 scopus 로고    scopus 로고
    • Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs
    • DOI 10.1515/BC.2008.026
    • P Lovis S Gattesco R Regazzi 2008 Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs Biol Chem 389 305 312 10.1515/BC.2008.026 1:CAS:528:DC%2BD1cXivFequr8%3D 18177263 (Pubitemid 351329024)
    • (2008) Biological Chemistry , vol.389 , Issue.3 , pp. 305-312
    • Lovis, P.1    Gattesco, S.2    Regazzi, R.3


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