Tumor necrosis factor receptor 2 signaling limits β-adrenergic receptor-mediated cardiac hypertrophy in vivo

Basic Research in Cardiology

Volumn 106, Issue 6, 2011, Pages 1193-1205

  Garlie, Jason B ^a,b   Hamid, Tariq ^a   Gu, Yan ^a   Ismahil, Mohamed Ameen ^a   Chandrasekar, Bysani ^c   Prabhu, Sumanth D ^a,b,d  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

^c TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Beta adrenergic receptor; Cardiac hypertrophy; Cytokines; Nuclear factor kappa B; Tumor necrosis factor

Indexed keywords

BETA ADRENERGIC RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; ISOPRENALINE; MONOCYTE CHEMOTACTIC PROTEIN 1; SODIUM CHLORIDE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC STIMULATION; CONTROLLED STUDY; CYTOKINE RESPONSE; DISEASE EXACERBATION; ENZYME ACTIVATION; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE HYPERTROPHY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; UPREGULATION; WILD TYPE;

ADRENERGIC BETA-AGONISTS; ANIMALS; BLOTTING, WESTERN; CARDIOMEGALY; ECHOCARDIOGRAPHY; ENZYME-LINKED IMMUNOSORBENT ASSAY; ISOPROTERENOL; MALE; MICE; MICE, KNOCKOUT; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84856734532     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-011-0196-6     Document Type: Article

References (46)

1. Aggarwal BB (2003) Signalling pathways of the TNF superfamily: a double-edged sword. Nat Rev Immunol 3:745-756 (Pubitemid 41070815)
2. Antos CL, Frey N, Marx SO, Reiken S, Gaburjakova M, Richardson JA, Marks AR, Olson EN (2001) Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase A. Circ Res 89:997-1004 (Pubitemid 34640866)
3. Bristow MR (2000) Beta-adrenergic receptor blockade in chronic heart failure. Circulation 101:558-569 (Pubitemid 30080872)
4. Burger A, Benicke M, Deten A, Zimmer HG (2001) Catecholamines stimulate interleukin-6 synthesis in rat cardiac fibroblasts. Am J Physiol Heart Circ Physiol 281:H14-H21
5. Chandrasekar B, Marelli-Berg FM, Tone M, Bysani S, Prabhu SD, Murray DR (2004) Beta-adrenergic stimulation induces interleukin-18 expression via β2-AR, PI3K, Akt, IKK, and NF-jB. Biochem Biophys Res Commun 319:304-311 (Pubitemid 38725947)
6. Deswal A, Petersen NJ, Feldman AM, Young JB, White BG, Mann DL (2001) Cytokines and cytokine receptors in advanced heart failure: an analysis of the cytokine database from the Vesnarinone trial (VEST). Circulation 103:2055-2059 (Pubitemid 32373007)
7. Ding P, Huang J, Battiprolu PK, Hill JA, Kamm KE, Stull JT (2010) Cardiac myosin light chain kinase is necessary for myosin regulatory light chain phosphorylation and cardiac performance in vivo. J Biol Chem 285:40819-40829
8. Engelhardt S, Hein L, Wiesmann F, Lohse MJ (1999) Progressive hypertrophy and heart failure in β1-adrenergic receptor transgenic mice. Proc Natl Acad Sci USA 96:7059-7064 (Pubitemid 29275009)
9. Freire G, Ocampo C, Ilbawi N, Griffin AJ, Gupta M (2007) Overt expression of AP-1 reduces α-myosin heavy chain expression and contributes to heart failure from chronic volume overload. J Mol Cell Cardiol 43:465-478 (Pubitemid 47451423)
10. Guggilam A, Cardinale JP, Mariappan N, Sriramula S, Haque M, Francis J (2011) Central TNF inhibition results in attenuated neurohumoral excitation in heart failure: a role for superoxide and nitric oxide. Basic Res Cardiol 106:273-286
11. Hamid T, Gu Y, Ortines RV, Bhattacharya C, Wang G, Xuan YT, Prabhu SD (2009) Divergent tumor necrosis factor receptor-related remodeling responses in heart failure: role of nuclear factor-κB and inflammatory activation. Circulation 119:1386-1397
12. Hamid T, Guo SZ, Kingery JR, Xiang X, Dawn B, Prabhu SD (2011) Cardiomyocyte NF-κB p65 promotes adverse remodelling, apoptosis, and endoplasmic reticulum stress in heart failure. Cardiovasc Res 89:129-138
13. Heusch P, Aker S, Boengler K, Deindl E, van de Sand A, Klein K, Rassaf T, Konietzka I, Sewell A, Menazza S, Canton M, Heusch G, Di Lisa F, Schulz R (2010) Increased inducible nitric oxide synthase and arginase II expression in heart failure: no net nitrite/nitrate production and protein S-nitrosylation. Am J Physiol Heart Circ Physiol 299: H446-H453
14. Honsho S, Nishikawa S, Amano K, Zen K, Adachi Y, Kishita E, Matsui A, Katsume A, Yamaguchi S, Nishikawa K, Isoda K, Riches DW, Matoba S, Okigaki M, Matsubara H (2009) Pressuremediated hypertrophy and mechanical stretch induces IL-1 release and subsequent IGF-1 generation to maintain compensative hypertrophy by affecting Akt and JNK pathways. Circ Res 105:1149-1158
15. 2+ channel currents in failing ventricular myocytes. Am J Physiol Heart Circ Physiol 300: H978-H988
16. House SL, House BE, Glascock B, Kimball T, Nusayr E, Schultz JE, Doetschman T (2010) Fibroblast growth factor 2 mediates isoproterenol-induced cardiac hypertrophy through activation of the extracellular regulated kinase. Mol Cell Pharmacol 2:143-154
17. Kleinbongard P, Heusch G, Schulz R (2010) TNF-α in atherosclerosis, myocardial ischemia/reperfusion and heart failure. Pharmacol Ther 127:295-314
18. Liggett SB, Tepe NM, Lorenz JN, Canning AM, Jantz TD, Mitarai S, Yatani A, Dorn GW 2nd (2000) Early and delayed consequences of β (2)-adrenergic receptor overexpression in mouse hearts: critical role for expression level. Circulation 101:1707-1714 (Pubitemid 30196632)
19. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-δδC (T)) method. Methods 25:402-408 (Pubitemid 34164012)
20. Luo J, Hill BG, Gu Y, Cai J, Srivastava S, Bhatnagar A, Prabhu SD (2007) Mechanisms of acrolein-induced myocardial dysfunction: implications for environmental and endogenous aldehyde exposure. Am J Physiol Heart Circ Physiol 293: H3673-H3684 (Pubitemid 350230913)
21. Mann DL (2002) Inflammatory mediators and the failing heart: past, present, and the foreseeable future. Circ Res 91:988-998 (Pubitemid 35416635)
22. Mann DL, Bristow MR (2005) Mechanisms and models in heart failure: the biomechanical model and beyond. Circulation 111:2837-2849 (Pubitemid 40791557)
23. Monden Y, Kubota T, Inoue T, Tsutsumi T, Kawano S, Ide T, Tsutsui H, Sunagawa K (2007) Tumor necrosis factor-α is toxic via receptor 1 and protective via receptor 2 in a murine model of myocardial infarction. Am J Physiol Heart Circ Physiol 293: H743-H753 (Pubitemid 47105137)
24. Murray DR, Prabhu SD, Chandrasekar B (2000) Chronic β-adrenergic stimulation induces myocardial proinflammatory cytokine expression. Circulation 101:2338-2341 (Pubitemid 30329120)
25. Oudit GY, Crackower MA, Eriksson U, Sarao R, Kozieradzki I, Sasaki T, Irie-Sasaki J, Gidrewicz D, Rybin VO, Wada T, Steinberg SF, Backx PH, Penninger JM (2003) Phosphoinositide 3-kinase γ-deficient mice are protected from isoproterenolinduced heart failure. Circulation 108:2147-2152 (Pubitemid 37337593)
26. Owan TE, Hodge DO, Herges RM, Jacobsen SJ, Roger VL, Redfield MM (2006) Trends in prevalence and outcome of heart failure with preserved ejection fraction. New Engl J Med 355:251-259 (Pubitemid 44079340)
27. Palmer JN, Hartogensis WE, Patten M, Fortuin FD, Long CS (1995) Interleukin-1β induces cardiac myocyte growth but inhibits cardiac fibroblast proliferation in culture. J Clin Invest 95:2555-2564
28. Prabhu SD (2004) Cytokine-induced modulation of cardiac function. Circ Res 95:1140-1153 (Pubitemid 39648205)
29. Prabhu SD, Chandrasekar B, Murray DR, Freeman GL (2000) β-adrenergic blockade in developing heart failure: effects on myocardial inflammatory cytokines, nitric oxide, and remodeling. Circulation 101:2103-2109 (Pubitemid 30233176)
30. Prabhu SD, Wang G, Luo J, Gu Y, Ping P, Chandrasekar B (2003) β-adrenergic receptor blockade modulates Bcl-X (S) expression and reduces apoptosis in failing myocardium. J Mol Cell Cardiol 35:483-493 (Pubitemid 36539454)
31. Purcell NH, Tang G, Yu C, Mercurio F, Di Donato JA, Lin A (2001) Activation of NF-κB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes. Proc Natl Acad Sci USA 98:6668-6673 (Pubitemid 32538274)
32. Qin F, Rounds NK, Mao W, Kawai K, Liang CS (2001) Antioxidant vitamins prevent cardiomyocyte apoptosis produced by norepinephrine infusion in ferrets. Cardiovasc Res 51:736-748 (Pubitemid 32800715)
33. Ramani R, Mathier M, Wang P, Gibson G, Togel S, Dawson J, Bauer A, Alber S, Watkins SC, McTiernan CF, Feldman AM (2004) Inhibition of tumor necrosis factor receptor-1-mediated pathways has beneficial effects in a murine model of postischemic remodeling. Am J Physiol Heart Circ Physiol 287: H1369-H1377 (Pubitemid 39096688)
34. Rauchhaus M, Doehner W, Francis DP, Davos C, Kemp M, Liebenthal C, Niebauer J, Hooper J, Volk HD, Coats AJ, Anker SD (2000) Plasma cytokine parameters and mortality in patients with chronic heart failure. Circulation 102:3060-3067
35. Reddy VS, Prabhu SD, Mummidi S, Valente AJ, Venkatesan B, Shanmugam P, Delafontaine P, Chandrasekar B (2010) Interleukin-18 induces EMMPRIN expression in primary cardiomyocytes via JNK/Sp1 signaling and MMP-9 in part via EMMPRIN and through AP-1 and NF-κB activation. Am J Physiol Heart Circ Physiol 299: H1242-H1254
36. Saadane N, Alpert L, Chalifour LE (1999) Expression of immediate early genes, GATA-4, and Nkx-2.5 in adrenergic-induced cardiac hypertrophy and during regression in adult mice. Br J Pharmacol 127:1165-1176 (Pubitemid 29326640)
37. Schulz R, Heusch G (2009) Tumor necrosis factor-α and its receptors 1 and 2: Yin and Yang in myocardial infarction? Circulation 119:1355-1357
38. Shan J, Kushnir A, Betzenhauser MJ, Reiken S, Li J, Lehnart SE, Lindegger N, Mongillo M, Mohler PJ, Marks AR (2010) Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice. J Clin Invest 120:4388-4398
39. Sharir T, Feldman MD, Haber H, Feldman AM, Marmor A, Becker LC, Kass DA (1994) Ventricular systolic assessment in patients with dilated cardiomyopathy by preload-adjusted maximal power. Validation and noninvasive application. Circulation 89:2045-2053 (Pubitemid 24142780)
40. Srivastava S, Chandrasekar B, Gu Y, Luo J, Hamid T, Hill BG, Prabhu SD (2007) Downregulation of CuZn-superoxide dismutase contributes to β-adrenergic receptor-mediated oxidative stress in the heart. Cardiovasc Res 74:445-455 (Pubitemid 46693706)
41. Thielmann M, Dorge H, Martin C, Belosjorow S, Schwanke U, van De Sand A, Konietzka I, Buchert A, Kruger A, Schulz R, Heusch G (2002) Myocardial dysfunction with coronary microembolization: signal transduction through a sequence of nitric oxide, tumor necrosis factor-alpha, and sphingosine. Circ Res 90:807-813 (Pubitemid 34633897)
42. Venkatachalam K, Prabhu SD, Reddy VS, Boylston WH, Valente AJ, Chandrasekar B (2009) Neutralization of interleukin-18 ameliorates ischemia/reperfusion-induced myocardial injury. J Biol Chem 284:7853-7865
43. Wang G, Hamid T, Keith RJ, Zhou G, Partridge CR, Xiang X, Kingery JR, Lewis RK, Li Q, Rokosh DG, Ford R, Spinale FG, Riggs DW, Srivastava S, Bhatnagar A, Bolli R, Prabhu SD (2010) Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart. Circulation 121:1912-1925
44. Yang Z, Zingarelli B, Szabo C (2000) Crucial role of endogenous interleukin-10 production in myocardial ischemia/reperfusion injury. Circulation 101:1019-1026 (Pubitemid 30131705)
45. Zhang GX, Kimura S, Nishiyama A, Shokoji T, Rahman M, Yao L, Nagai Y, Fujisawa Y, Miyatake A, Abe Y (2005) Cardiac oxidative stress in acute and chronic isoproterenol-infused rats. Cardiovasc Res 65:230-238 (Pubitemid 40038496)
46. Zymek P, Nah DY, Bujak M, Ren G, Koerting A, Leucker T, Huebener P, Taffet G, Entman M, Frangogiannis NG (2007) Interleukin-10 is not a critical regulator of infarct healing and left ventricular remodeling. Cardiovasc Res 74:313-322 (Pubitemid 46517506)