Decrease in the density of t-tubular L-type Ca2+ channel currents in failing ventricular myocytes

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 300, Issue 3, 2011, Pages

  Horiuchi Hirose, Miwa ^a   Kashihara, Toshihide ^a   Nakada, Tsutomu ^a   Kurebayashi, Nagomi ^b   Shimojo, Hisashi ^a   Shibazaki, Toshihide ^a   Sheng, Xiaona ^c   Yano, Shiharu ^a   Hirose, Masamichi ^a   Hongo, Minoru ^d   Sakurai, Takashi ^b   Moriizumi, Tetsuji ^a   Ueda, Hideho ^d   Yamada, Mitsuhiko ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d SHINSHU UNIVERSITY   (Japan)

Author keywords

adrenergic receptors; Calmodulin dependent protein kinase II; Protein kinase A; Protein phosphatases; Ryanodine receptors

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CHANNEL L TYPE; CYCLIC AMP DEPENDENT PROTEIN KINASE; ISOPRENALINE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2;

ADRENERGIC STIMULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; HEART FAILURE; HEART HYPERTROPHY; HEART VENTRICLE HYPERTROPHY; MOUSE; MUSCLE CELL; NONHUMAN; OSMOTIC STRESS; PRIORITY JOURNAL; TRANSVERSE TUBULAR SYSTEM; WHOLE CELL;

ANIMALS; CALCIUM CHANNELS, L-TYPE; CARDIOTONIC AGENTS; HEART FAILURE; ISOPROTERENOL; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PHOSPHOTRANSFERASES; PROTEIN PHOSPHATASE 1; PROTEIN PHOSPHATASE 2; SARCOPLASMIC RETICULUM;

EID: 79955068039     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00508.2010     Document Type: Article

References (37)

1. 2+ leak in heart failure. Circ Res 97: 1314-1322, 2005.
2. Bers MD. (editor). Heart failure. In: Excitation-Contraction Coupling and Cardiac Contractile Force. Dordrecht, The Netherlands: Springer, 2008, p. 316-323.
3. Boknik P, Fockenbrock M, Herzig S, Knapp J, Linck B, Luss H, Muller FU, Muller T, Schmitz W, Schroder F, Neumann J. Protein phosphatase activity is increased in a rat model of long-term β-adrenergic stimulation. Naunyn Schmiedebergs Arch Pharmacol 362: 222-231, 2000.
4. Brette F, Salle L, Orchard CH. Quantification of calcium entry at the T-tubules and surface membrane in rat ventricular myocytes. Biophys J 90: 381-389, 2006.
5. Curran J, Hinton MJ, Rios E, Bers DM, Shannon TR. β-Adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase. Circ Res 100: 391-398, 2007.
6. Davare MA, Horne MC, Hell JW. Protein phosphatase 2A is associated with class C L-type calcium channels (Cav1.2) and antagonizes channel phosphorylation by cAMP-dependent protein kinase. J Biol Chem 275: 39710-39717, 2000.
7. Doerr T, Denger R, Doerr A, Trautwein W. Ionic currents contributing to the action potential in single ventricular myocytes of the guinea pig studied with action potential clamp. Pflügers Arch 416: 230-237, 1990.
8. Fabiato A. Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum. Am J Physiol Cell Physiol 245: C1-C14, 1983.
9. Franzini-Armstrong C, Protasi F. Ryanodine receptors of striated muscles: a complex channel capable of multiple interactions. Physiol Rev 77: 699-729, 1997.
10. Gomez AM, Guatimosim S, Dilly KW, Vassort G, Lederer WJ. Heart failure after myocardial infarction: altered excitation-contraction coupling. Circulation 104: 688-693, 2001.
11. Gomez AM, Valdivia HH, Cheng H, Lederer MR, Santana LF, Cannell MB, McCune SA, Altschuld RA, Lederer WJ. Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure. Science 276: 800-806, 1997.
12. Hall DD, Feekes JA, Arachchige Don AS, Shi M, Hamid J, Chen L, Strack S, Zamponi GW, Horne MC, Hell JW. Binding of protein phosphatase 2A to the L-type calcium channel Cav1.2 next to Ser1928, its main PKA site, is critical for Ser1928 dephosphorylation. Biochemistry 45: 3448-3459, 2006.
13. 2+ channels in canine tachycardia-induced heart failure. Cardiovasc Res 49: 298-307, 2001.
14. 2+ release in myocytes from chronically ischemic myocardium. Circ Res 102: 338-346, 2008.
15. Herzig S, Neumann J. Effects of serine/threonine protein phosphatases on ion channels in excitable membranes. Physiol Rev 80: 173-210, 2000.
16. Kamiyoshi Y, Takahashi M, Yokoseki O, Yazaki Y, Hirose S, Morimoto H, Watanabe N, Kinoshita O, Hongo M, Ikeda U. Mycophenolate mofetil prevents the development of experimental autoimmune myocarditis. J Mol Cell Cardiol 39: 467-477, 2005.
17. Kawai M, Hussain M, Orchard CH. Excitation-contraction coupling in rat ventricular myocytes after formamide-induced detubulation. Am J Physiol Heart Circ Physiol 277: H603-H609, 1999.
18. Lehnart SE, Schillinger W, Pieske B, Prestle J, Just H, Hasenfuss G. Sarcoplasmic reticulum proteins in heart failure. Ann NY Acad Sci 853: 220-230, 1998.
19. Lyon AR, MacLeod KT, Zhang Y, Garcia E, Kanda GK, Lab MJ, Korchev YE, Harding SE, Gorelik J. Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart. Proc Natl Acad Sci USA 106: 6854-6859, 2009.
20. MacLennan DH, Kranias EG. Phospholamban: a crucial regulator of cardiac contractility. Nat Rev Mol Cell Biol 4: 566-577, 2003.
21. Mann DL. Pathophysiology of heart failure. In: Heart Diseases (8 ed.), edited by Libby P, Bonow RO, Mann DL, Zipes DP, Braunwald E. Philadelphia, PA: Saunders Elsevier, 2008, p. 541-560.
22. Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 101: 365-376, 2000.
23. McCall E, Ginsburg KS, Bassani RA, Shannon TR, Qi M, Samarel AM, Bers DM. Ca flux, contractility, and excitation-contraction coupling in hypertrophic rat ventricular myocytes. Am J Physiol Heart Circ Physiol 274: H1348-H1360, 1998.
24. McDonald TF, Pelzer S, Trautwein W, Pelzer DJ. Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells. Physiol Rev 74: 365-507, 1994.
25. Meszaros J, Coutinho JJ, Bryant SM, Ryder KO, Hart G. L-type calcium current in catecholamine-induced cardiac hypertrophy in the rat. Exp Physiol 82: 71-83, 1997.
26. Mukherjee R, Spinale FG. L-type calcium channel abundance and function with cardiac hypertrophy and failure: a review. J Mol Cell Cardiol 30: 1899-1916, 1998.
27. Nattel S, Maguy A, Le Bouter S, Yeh YH. Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation. Physiol Rev 87: 425-456, 2007.
28. Osadchii OE. Cardiac hypertrophy induced by sustained β-adrenoreceptor activation: pathophysiological aspects. Heart Fail Rev 12: 66-86, 2007.
29. 2+-ATPase and phospholamban in the failing and nonfailing heart. Cardiovasc Res 45: 245-252, 2000.
30. Rockman HA, Koch WJ, Lefkowitz RJ. Seven-transmembrane-spanning receptors and heart function. Nature 415: 206-212, 2002.
31. Schroder F, Handrock R, Beuckelmann DJ, Hirt S, Hullin R, Priebe L, Schwinger RH, Weil J, Herzig S. Increased availability and open probability of single L-type calcium channels from failing compared with nonfailing human ventricle. Circulation 98: 969-976, 1998.
32. 2+ sparks) originate at transverse tubules in rat heart cells. J Physiol 487: 601-608, 1995.
33. Solaro RJ, Rarick HM. Troponin and tropomyosin: proteins that switch on and tune in the activity of cardiac myofilaments. Circ Res 83: 471-480, 1998.
34. Song LS, Sobie EA, McCulle S, Lederer WJ, Balke CW, Cheng H. Orphaned ryanodine receptors in the failing heart. Proc Natl Acad Sci USA 103: 4305-4310, 2006.
35. 2+/calmodulin kinase signaling pathway. Circ Res 95: 798-806, 2004.
36. 2+ sparks, and local control of excitation-contraction coupling in normal heart muscle. Circ Res 85: 770-776, 1999.
37. Ks channel suppression in guinea pig ventricular myocytes. J Membr Biol 222: 151-166, 2008.