Overt expression of AP-1 reduces alpha myosin heavy chain expression and contributes to heart failure from chronic volume overload

Journal of Molecular and Cellular Cardiology

Volumn 43, Issue 4, 2007, Pages 465-478

  Freire, Grace ^a   Ocampo, Catherina ^a   Ilbawi, Nadim ^a   Griffin, Andrew J ^a,c   Gupta, Madhu ^a,b,c  

^a ADVOCATE CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

AP 1; Compensatory cardiac hypertrophy; Gene expression; Heart failure; Myosin heavy chain; Transcription factors; Volume overload

Indexed keywords

BETA ACTIN; COLECALCIFEROL RECEPTOR; HEAT SHOCK PROTEIN; MYOSIN HEAVY CHAIN ALPHA; NUCLEAR PROTEIN; PROTEIN C JUN; RETINOID X RECEPTOR; STAT4 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR YY1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA BINDING; GENE OVEREXPRESSION; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS;

ANIMALS; BODY WEIGHT; CARDIAC VOLUME; CARDIOMEGALY; CHRONIC DISEASE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENES, FOS; GENES, JUN; HEART FAILURE; MALE; MYOCARDIUM; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; VENTRICULAR FUNCTION, LEFT; VENTRICULAR MYOSINS;

RATTUS;

EID: 34548825939     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2007.07.046     Document Type: Article

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