Reductive activation of 5-fluorodeoxyuridine prodrug possessing azide methyl group by hypoxic X-irradiation

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 4, 2012, Pages 1682-1685

  Tanabe, Kazuhito ^a   Ishizaki, Jin ^a   Ando, Yuichirou ^a   Ito, Takeo ^a   Nishimoto, Sei Ichi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

5 Fluorodeoxyuridine; Azide methyl group; Hypoxic X irradiation; Prodrug; Reductive activation

Indexed keywords

AZIDE; FLOXURIDINE; METHYL GROUP; PRODRUG;

ARTICLE; DRUG ACTIVATION; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; X IRRADIATION;

EID: 84856667682     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.12.106     Document Type: Article

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