One-electron reduction characteristics of N(3)-substituted 5-fluorodeoxyuridines synthesized as radiation-activated prodrugs

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 21, 2003, Pages 4551-4556

  Tanabe, Kazuhito ^a   Mimasu, Youhei ^a   Eto, Akira ^a   Tachi, Yukihiro ^a   Sakakibara, Shingo ^a   Mori, Mayuko ^a   Hatta, Hiroshi ^a   Nishimoto, Sei Ichi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2' DEOXY 5 FLUORO 3 (2' OXOCYCLOPENTYL)URIDINE; ANTINEOPLASTIC AGENT; FLOXURIDINE; FLOXURIDINE DERIVATIVE; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CYCLIC POTENTIOMETRY; CYTOTOXICITY; DRUG DESIGN; DRUG RELEASE; DRUG SYNTHESIS; ELECTRON; HYPOXIA; MOUSE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RADIATION; REDUCTION; THIN LAYER CHROMATOGRAPHY;

EID: 0141504177     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2003.08.001     Document Type: Article

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