-
1
-
-
54449093310
-
CNS disorders - Current treatment options and the prospects for advanced therapies
-
DiNunzio JC, Williams RO 3rd. CNS disorders - current treatment options and the prospects for advanced therapies. Drug Dev. Ind. Pharm. 34(11), 1141-1167 (2008).
-
(2008)
Drug Dev. Ind. Pharm.
, vol.34
, Issue.11
, pp. 1141-1167
-
-
Dinunzio, J.C.1
Williams Iii., R.O.2
-
2
-
-
79955438992
-
Developing predictive CSF biomarkers: A challenge critical to success in Alzheimer's disease and neuropsychiatric translational medicine
-
Flood DG, Marek GJ, Williams M. Developing predictive CSF biomarkers: a challenge critical to success in Alzheimer's disease and neuropsychiatric translational medicine. Biochem. Pharmacol. 81(12), 1422-1234 (2011).
-
(2011)
Biochem. Pharmacol.
, vol.81
, Issue.12
, pp. 1422-1234
-
-
Flood, D.G.1
Marek, G.J.2
Williams, M.3
-
3
-
-
55849092248
-
Translational medicine perspectives of biomarkers in drug discovery and development: Part 1 target selection and validation - Biomarkers take center stage
-
Feuerstein GZ, Ruffolo RR Jr, Stiles G, Walsh FS, Rutkowski JL. Translational medicine perspectives of biomarkers in drug discovery and development: part 1 target selection and validation - biomarkers take center stage. Am. Drug Discov. 2(5), 36-43 (2007).
-
(2007)
Am. Drug Discov.
, vol.2
, Issue.5
, pp. 36-43
-
-
Feuerstein, G.Z.1
Ruffolo Jr., R.R.2
Stiles, G.3
Walsh, F.S.4
Rutkowski, J.L.5
-
4
-
-
62949153662
-
Translational medicine perspectives in drug discovery and development part 2: Target compound interaction the vastly neglected biomarkers contributing to early clinical development failure
-
Feuerstein GZ, Dormer C, Ruffolo RR Jr, Rutkowski JL, Walsh FS, Hurko O. Translational medicine perspectives in drug discovery and development part 2: target compound interaction the vastly neglected biomarkers contributing to early clinical development failure. Am. Drug Discov. 3(2), 48-54 (2008).
-
(2008)
Am. Drug Discov.
, vol.3
, Issue.2
, pp. 48-54
-
-
Feuerstein, G.Z.1
Dormer, C.2
Ruffolo Jr., R.R.3
Rutkowski, J.L.4
Walsh, F.S.5
Hurko, O.6
-
5
-
-
55849092248
-
Translational medicine perspectives in drug discovery and development part 3: Disease biomarkers, disease modifying biomarkers, disease labeling biomarkers and surrogate biomarkers
-
Feuerstein GZ, Dormer C, Walsh FS, Hurko O, Rutkowski JL. Translational medicine perspectives in drug discovery and development part 3: disease biomarkers, disease modifying biomarkers, disease labeling biomarkers and surrogate biomarkers. Am. Drug Discov. 2(4), 36-41 (2008).
-
(2008)
Am. Drug Discov.
, vol.2
, Issue.4
, pp. 36-41
-
-
Feuerstein, G.Z.1
Dormer, C.2
Walsh, F.S.3
Hurko, O.4
Rutkowski, J.L.5
-
6
-
-
46949103549
-
Cerebrospinal fluid biomarkers of neurodegeneration in chronic neurological diseases
-
DOI 10.1586/14737159.8.4.479
-
Tumani H, Teunissen C, Sussmuth S, Otto M, Ludolph AC, Brettschneider J. Cerebrospinal fluid biomarkers of neurodegeneration in chronic neurological diseases. Exp. Rev. Mol. Diagn. 8(4), 479-494 (2008). (Pubitemid 351962092)
-
(2008)
Expert Review of Molecular Diagnostics
, vol.8
, Issue.4
, pp. 479-494
-
-
Tumani, H.1
Teunissen, C.2
Sussmuth, S.3
Otto, M.4
Ludolph, A.C.5
Brettschneider, J.6
-
7
-
-
80051728609
-
Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: Similarities and differences
-
Redzic Z. Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: similarities and differences. Fluids Barriers CNS 8(1), 3 (2011).
-
(2011)
Fluids Barriers CNS
, vol.8
, Issue.1
, pp. 3
-
-
Redzic, Z.1
-
8
-
-
67149098346
-
Safety of lumbar puncture procedures in patients with Alzheimer's disease
-
Peskind E, Nordberg A, Darreh-Shori T, Soininen H. Safety of lumbar puncture procedures in patients with Alzheimer's disease. Curr. Alzheimer Res. 6(3), 290-292 (2009).
-
(2009)
Curr. Alzheimer Res.
, vol.6
, Issue.3
, pp. 290-292
-
-
Peskind, E.1
Nordberg, A.2
Darreh-Shori, T.3
Soininen, H.4
-
9
-
-
59449088199
-
Atraumatic lumbar puncture needles: After all these years, are we still missing the point?
-
Arendt K, Demaerschalk BM, Wingerchuk DM, Camann W. Atraumatic lumbar puncture needles: after all these years, are we still missing the point? Neurologist 15(1), 17-20 (2009).
-
(2009)
Neurologist
, vol.15
, Issue.1
, pp. 17-20
-
-
Arendt, K.1
Demaerschalk, B.M.2
Wingerchuk, D.M.3
Camann, W.4
-
10
-
-
65249117394
-
Use of CSF biomarkers in Alzheimer's disease clinical trials
-
Blennow K, Zetterberg H. Use of CSF biomarkers in Alzheimer's disease clinical trials. J. Nutr. Health Aging 13(4), 358-361 (2009).
-
(2009)
J. Nutr. Health Aging
, vol.13
, Issue.4
, pp. 358-361
-
-
Blennow, K.1
Zetterberg, H.2
-
11
-
-
33750975073
-
International quality control survey of neurochemical dementia diagnostics
-
DOI 10.1016/j.neulet.2006.07.009, PII S0304394006006768
-
Lewczuk P, Beck G, Ganslandt O, et al. International quality control survey of neurochemical dementia diagnostics. Neurosci. Lett. 409(1), 1-4 (2006). (Pubitemid 44740057)
-
(2006)
Neuroscience Letters
, vol.409
, Issue.1
, pp. 1-4
-
-
Lewczuk, P.1
Beck, G.2
Ganslandt, O.3
Esselmann, H.4
Deisenhammer, F.5
Regeniter, A.6
Petereit, H.-F.7
Tumani, H.8
Gerritzen, A.9
Oschmann, P.10
Schroder, J.11
Schonknecht, P.12
Zimmermann, K.13
Hampel, H.14
Burger, K.15
Otto, M.16
Haustein, S.17
Herzog, K.18
Dannenberg, R.19
Wurster, U.20
Bibl, M.21
Maler, J.M.22
Reubach, U.23
Kornhuber, J.24
Wiltfang, J.25
more..
-
12
-
-
47849103803
-
Increased α-defensins as a blood marker for schizophrenia susceptibility
-
DOI 10.1074/mcp.M700459-MCP200
-
Craddock RM, Huang JT, Jackson E, et al. Increased a-defensins as a blood marker for schizophrenia susceptibility. Mol. Cell Proteomics 7(7), 1204-1213 (2008). (Pubitemid 352038267)
-
(2008)
Molecular and Cellular Proteomics
, vol.7
, Issue.7
, pp. 1204-1213
-
-
Craddock, R.M.1
Huang, J.T.2
Jackson, E.3
Harris, N.4
Torrey, E.F.5
Herberth, M.6
Bahn, S.7
-
13
-
-
79952808102
-
CSF biomarkers in neurodegenerative diseases
-
Mattsson N. CSF biomarkers in neurodegenerative diseases. Clin. Chem. Lab. Med. 49(3), 345-352 (2011).
-
(2011)
Clin. Chem. Lab. Med.
, vol.49
, Issue.3
, pp. 345-352
-
-
Mattsson, N.1
-
14
-
-
79952793175
-
Amyloid b (Ab) and phospho-tau (p-tau) as diagnostic biomarkers in Alzheimer's disease
-
Prvulovic D, Hampel H. Amyloid b (Ab) and phospho-tau (p-tau) as diagnostic biomarkers in Alzheimer's disease. Clin. Chem. Lab. Med. 49(3), 367-374 (2011).
-
(2011)
Clin. Chem. Lab. Med.
, vol.49
, Issue.3
, pp. 367-374
-
-
Prvulovic, D.1
Hampel, H.2
-
15
-
-
77949444966
-
Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections
-
Domenici E, Wille DR, Tozzi F, et al. Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections. PLoS ONE 5(2), e9166 (2010).
-
(2010)
PLoS ONE
, vol.5
, Issue.2
-
-
Domenici, E.1
Wille, D.R.2
Tozzi, F.3
-
16
-
-
77952674096
-
Diagnostic classification of schizophrenia by neural network analysis of blood-based gene expression signatures
-
Takahashi M, Hayashi H, Watanabe Y, et al. Diagnostic classification of schizophrenia by neural network analysis of blood-based gene expression signatures. Schizophr. Res. 119(1-3), 210-218 (2010).
-
(2010)
Schizophr. Res.
, vol.119
, Issue.1-3
, pp. 210-218
-
-
Takahashi, M.1
Hayashi, H.2
Watanabe, Y.3
-
17
-
-
60249102897
-
The leukocytes expressing DARPP-32 are reduced in patients with schizophrenia and bipolar disorder
-
Torres KC, Souza BR, Miranda DM, et al. The leukocytes expressing DARPP-32 are reduced in patients with schizophrenia and bipolar disorder. Prog. Neuropsychopharmacol. Biol. Psychiatry 33(2), 214-219 (2009).
-
(2009)
Prog. Neuropsychopharmacol. Biol. Psychiatry
, vol.33
, Issue.2
, pp. 214-219
-
-
Torres, K.C.1
Souza, B.R.2
Miranda, D.M.3
-
18
-
-
0023250045
-
Antidepressant monoamine oxidase inhibitors enhance serotonin but not norepinephrine neurotransmission
-
Blier P, de Montigny C. Antidepressant monoamine oxidase inhibitors enhance serotonin but not norepinephrine neurotransmission. Psychopharmacol. Ser. 3, 127-134 (1987).
-
(1987)
Psychopharmacol. Ser.
, vol.3
, pp. 127-134
-
-
Blier, P.1
De Montigny, C.2
-
19
-
-
0020632275
-
Effects of desmethylimipramine on plasma norepinephrine, pulse, and blood pressure
-
Ross RJ, Zavadil AP 3rd, Calil HM, et al. Effects of desmethylimipramine on plasma norepinephrine, pulse, and blood pressure. Clin. Pharmacol. Ther. 33(4), 429-437 (1983). (Pubitemid 13093761)
-
(1983)
Clinical Pharmacology and Therapeutics
, vol.33
, Issue.4
, pp. 429-437
-
-
Ross, R.J.1
Zavadil III, A.P.2
Calil, H.M.3
-
20
-
-
0028308388
-
Sympathetic nervous system activity in major depression: Basal and desipramine-induced alterations in plasma norepinephrine kinetics
-
Veith RC, Lewis N, Linares OA, et al. Sympathetic nervous system activity in major depression. Basal and desipramine-induced alterations in plasma norepinephrine kinetics. Arch. Gen. Psychiatry 51(5), 411-422 (1994). (Pubitemid 24176819)
-
(1994)
Archives of General Psychiatry
, vol.51
, Issue.5
, pp. 411-422
-
-
Veith, R.C.1
Lewis, N.2
Linares, O.A.3
Barnes, R.F.4
Raskind, M.A.5
Villacres, E.C.6
Murburg, M.M.7
Ashleigh, E.A.8
Castillo, S.9
Peskind, E.R.10
Pascualy, M.11
Halter, J.B.12
-
21
-
-
0033674519
-
Pharmacokinetics and safety of duloxetine, a dual-serotonin and norepinephrine reuptake inhibitor
-
Sharma A, Goldberg MJ, Cerimele BJ. Pharmacokinetics and safety of duloxetine, a dual-serotonin and norepinephrine reuptake inhibitor. J. Clin. Pharmacol. 40(2), 161-167 (2000).
-
(2000)
J. Clin. Pharmacol.
, vol.40
, Issue.2
, pp. 161-167
-
-
Sharma, A.1
Goldberg, M.J.2
Cerimele, B.J.3
-
22
-
-
0027475388
-
LY248686, a new inhibitor of serotonin and norepinephrine uptake
-
Wong DT, Bymaster FP, Mayle DA, Reid LR, Krushinski JH, Robertson DW. LY248686, a new inhibitor of serotonin and norepinephrine uptake. Neuropsychopharmacology 8(1), 23-33 (1993). (Pubitemid 23011155)
-
(1993)
Neuropsychopharmacology
, vol.8
, Issue.1
, pp. 23-33
-
-
Wong, D.T.1
Bymaster, F.P.2
Mayle, D.A.3
Reid, L.R.4
Krushinski, J.H.5
Robertson, D.W.6
-
23
-
-
4444224449
-
Clinical assessment of norepinephrine transporter blockade through biochemical and pharmacological profiles
-
Vincent S, Bieck PR, Garland EM, et al. Clinical assessment of norepinephrine transporter blockade through biochemical and pharmacological profiles. Circulation 109(25), 3202-3207 (2004).
-
(2004)
Circulation
, vol.109
, Issue.25
, pp. 3202-3207
-
-
Vincent, S.1
Bieck, P.R.2
Garland, E.M.3
-
24
-
-
84873070512
-
Use of a biomarker of norepinephrine transporter (NET) inhibition to assess atomoxetine effects during clinically recommended dosing
-
Amsterdam, The Netherlands, 22-26 October
-
Leibowitz MEL, Lin Q, Ledent E, et al. Use of a biomarker of norepinephrine transporter (NET) inhibition to assess atomoxetine effects during clinically recommended dosing. Presented at: Proceedings of the 18th ECNP Congress. Amsterdam, The Netherlands, 22-26 October 2005.
-
(2005)
Proceedings of the 18th ECNP Congress
-
-
Leibowitz, M.E.L.1
Lin, Q.2
Ledent, E.3
-
25
-
-
12244298956
-
Atomoxetine in adults with ADHD: Two randomized, placebo-controlled studies
-
DOI 10.1016/S0006-3223(02)01671-2
-
Michelson D, Adler L, Spencer T, et al. Atomoxetine in adults with ADHD: two randomized, placebo-controlled studies. Biol. Psychiatry 53(2), 112-120 (2003). (Pubitemid 36126473)
-
(2003)
Biological Psychiatry
, vol.53
, Issue.2
, pp. 112-120
-
-
Michelson, D.1
Adler, L.2
Spencer, T.3
Reimherr, F.W.4
West, S.A.5
Allen, A.J.6
Kelsey, D.7
Wernicke, J.8
Dietrich, A.9
Milton, D.10
-
26
-
-
0036848458
-
Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: A potential mechanism for efficacy in attention deficit/hyperactivity disorder
-
DOI 10.1016/S0893-133X(02)00346-9, PII S0893133X02003469
-
Bymaster FP, Katner JS, Nelson DL, et al. Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder. Neuropsychopharmacology 27(5), 699-711 (2002). (Pubitemid 35335888)
-
(2002)
Neuropsychopharmacology
, vol.27
, Issue.5
, pp. 699-711
-
-
Bymaster, F.P.1
Katner, J.S.2
Nelson, D.L.3
Hemrick-Luecke, S.K.4
Threlkeld, P.G.5
Heiligenstein, J.H.6
Morin, S.M.7
Gehlert, D.R.8
Perry, K.W.9
-
27
-
-
67349158641
-
The histamine H3 receptor as a therapeutic drug target for CNS disorders
-
Gemkow MJ, Davenport AJ, Harich S, Ellenbroek BA, Cesura A, Hallett D. The histamine H3 receptor as a therapeutic drug target for CNS disorders. Drug Discov. Today 14(9-10), 509-515 (2009).
-
(2009)
Drug Discov. Today
, vol.14
, Issue.9-10
, pp. 509-515
-
-
Gemkow, M.J.1
Davenport, A.J.2
Harich, S.3
Ellenbroek, B.A.4
Cesura, A.5
Hallett, D.6
-
28
-
-
73949133632
-
Regional differential effects of the novel histamine H3 receptor antagonist 6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3- benzazepin-7-yl)oxy]-N- methyl-3-p yridinecarboxamide hydrochloride (GSK189254) on histamine release in the central nervous system of freely moving rats
-
Giannoni P, Medhurst AD, Passani MB, et al. Regional differential effects of the novel histamine H3 receptor antagonist 6-[(3-cyclobutyl-2,3,4,5- tetrahydro-1H-3- benzazepin-7-yl)oxy]-N-methyl-3-p yridinecarboxamide hydrochloride (GSK189254) on histamine release in the central nervous system of freely moving rats. J. Pharmacol. Exp. Ther. 332(1), 164-172 (2010).
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.332
, Issue.1
, pp. 164-172
-
-
Giannoni, P.1
Medhurst, A.D.2
Passani, M.B.3
-
29
-
-
78650776401
-
H3 receptor antagonism increases methylhistamine levels in the cerebrospinal fluid of dogs and healthy human volunteers
-
Soares H, Wager T, Schmidt A, et al. H3 receptor antagonism increases methylhistamine levels in the cerebrospinal fluid of dogs and healthy human volunteers. Alzheimers Dement. 5(4), 254-255 (2009).
-
(2009)
Alzheimers Dement.
, vol.5
, Issue.4
, pp. 254-255
-
-
Soares, H.1
Wager, T.2
Schmidt, A.3
-
30
-
-
60249093377
-
Muscarinic agonists for the treatment of cognition in schizophrenia
-
Sellin AK, Shad M, Tamminga C. Muscarinic agonists for the treatment of cognition in schizophrenia. CNS Spectr. 13(11), 985-996 (2008).
-
(2008)
CNS Spectr.
, vol.13
, Issue.11
, pp. 985-996
-
-
Sellin, A.K.1
Shad, M.2
Tamminga, C.3
-
31
-
-
0026476297
-
Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors
-
Nitsch RM, Slack BE, Wurtman RJ, Growdon JH. Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science 258(5080), 304-307 (1992).
-
(1992)
Science
, vol.258
, Issue.5080
, pp. 304-307
-
-
Nitsch, R.M.1
Slack, B.E.2
Wurtman, R.J.3
Growdon, J.H.4
-
32
-
-
0034528416
-
M1 muscarinic agonists as potential disease-modifying agents in Alzheimer's disease: Rationale and perspectives
-
Fisher A, Michaelson DM, Brandeis R, Haring R, Chapman S, Pittel Z. M1 muscarinic agonists as potential disease-modifying agents in Alzheimer's disease. Rationale and perspectives. Ann. NY Acad. Sci. 920, 315-320 (2000). (Pubitemid 32056587)
-
(2000)
Annals of the New York Academy of Sciences
, vol.920
, pp. 315-320
-
-
Fisher, A.1
Michaelson, D.M.2
Brandeis, R.3
Haring, R.4
Chapman, S.5
Pittel, Z.6
-
33
-
-
0035968057
-
Reduction of cerebrospinal fluid amyloid β after systemic administration of M1 muscarinic agonists
-
DOI 10.1016/S0006-8993(01)02484-2, PII S0006899301024842
-
Beach TG, Walker DG, Potter PE, Sue LI, Fisher A. Reduction of cerebrospinal fluid amyloid b after systemic administration of M1 muscarinic agonists. Brain Res. 905(1-2), 220-223 (2001). (Pubitemid 32553856)
-
(2001)
Brain Research
, vol.905
, Issue.1-2
, pp. 220-223
-
-
Beach, T.G.1
Walker, D.G.2
Potter, P.E.3
Sue, L.I.4
Fisher, A.5
-
34
-
-
12444313989
-
42 in patients with Alzheimer's disease
-
Hock C, Maddalena A, Raschig A, et al. Treatment with the selective muscarinic m1 agonist talsaclidine decreases cerebrospinal fluid levels of A b 42 in patients with Alzheimer's disease. Amyloid 10(1), 1-6 (2003). (Pubitemid 36520922)
-
(2003)
Amyloid
, vol.10
, Issue.1
, pp. 1-6
-
-
Hock, C.1
Maddalena, A.2
Raschig, A.3
Muller-Spahn, F.4
Eschweiler, G.5
Hager, K.6
Heuser, I.7
Hampel, H.8
Muller-Thomsen, T.9
Oertel, W.10
Wienrich, M.11
Signorell, A.12
Gonzalez-Agosti, C.13
Nitsch, R.M.14
-
35
-
-
0029146932
-
Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression
-
Maes M, Meltzer HY, Bosmans E, et al. Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression. J. Affect. Disord. 34(4), 301-309 (1995).
-
(1995)
J. Affect. Disord.
, vol.34
, Issue.4
, pp. 301-309
-
-
Maes, M.1
Meltzer, H.Y.2
Bosmans, E.3
-
36
-
-
0030879129
-
Stress and depression: Is neuroimmunology the missing link?
-
Price LH, Rasmussen SA. Stress and depression: is neuroimmunology the missing link? Harv. Rev. Psychiat. 5(2), 108-112 (1997). (Pubitemid 27333282)
-
(1997)
Harvard Review of Psychiatry
, vol.5
, Issue.2
, pp. 108-112
-
-
Price, L.H.1
Rasmussen, S.A.2
-
37
-
-
0031973071
-
Forced swim test-induced endocrine and immune changes in the rat: Effect of subacute desipramine treatment
-
DOI 10.1016/S0091-3057(97)00316-X, PII S009130579700316X
-
Connor TJ, Kelly JP, Leonard BE. Forced swim test-induced endocrine and immune changes in the rat: effect of subacute desipramine treatment. Pharmacol. Biochem. Behav. 59(1), 171-177 (1998). (Pubitemid 28053695)
-
(1998)
Pharmacology Biochemistry and Behavior
, vol.59
, Issue.1
, pp. 171-177
-
-
Connor, T.J.1
Kelly, J.P.2
Leonard, B.E.3
-
38
-
-
0028846024
-
Intracerebroventricular interleukin-1 receptor antagonist blocks the enhancement of fear conditioning and interference with escape produced by inescapable shock
-
Maier SF, Watkins LR. Intracerebroventricular interleukin-1 receptor antagonist blocks the enhancement of fear conditioning and interference with escape produced by inescapable shock. Brain Res. 695(2), 279-282 (1995).
-
(1995)
Brain Res.
, vol.695
, Issue.2
, pp. 279-282
-
-
Maier, S.F.1
Watkins, L.R.2
-
39
-
-
33748168698
-
Interferon-induced depression in chronic hepatitis C: A review of its prevalence, risk factors, biology, and treatment approaches
-
DOI 10.1097/01.mcg.0000210099.36500.fe, PII 0000483620060400000010
-
Asnis GM, De La Garza R 2nd. Interferon-induced depression in chronic hepatitis C: a review of its prevalence, risk factors, biology, and treatment approaches. J. Clin.Gastroenterol. 40(4), 322-335 (2006). (Pubitemid 44309525)
-
(2006)
Journal of Clinical Gastroenterology
, vol.40
, Issue.4
, pp. 322-335
-
-
Asnis, G.M.1
De La Garza, R.2
-
40
-
-
34447628313
-
Depression following pegylated interferon-alpha: Characteristics and vulnerability
-
DOI 10.1016/j.jpsychores.2007.05.013, PII S0022399907002164
-
Lotrich FE, Rabinovitz M, Gironda P, Pollock BG. Depression following pegylated interferon-a: characteristics and vulnerability. J. Psychosom. Res. 63(2), 131-135 (2007). (Pubitemid 47088561)
-
(2007)
Journal of Psychosomatic Research
, vol.63
, Issue.2
, pp. 131-135
-
-
Lotrich, F.E.1
Rabinovitz, M.2
Gironda, P.3
Pollock, B.G.4
-
41
-
-
0035028913
-
Cytokines and etiopathogenesis of pervasive developmental disorders
-
DOI 10.1054/mehy.2000.1278
-
Malek-Ahmadi P. Cytokines and etiopathogenesis of pervasive developmental disorders. Med. Hypothes. 56(3), 321-324 (2001). (Pubitemid 32382350)
-
(2001)
Medical Hypotheses
, vol.56
, Issue.3
, pp. 321-324
-
-
Malek-Ahmadi, P.1
-
42
-
-
0032718722
-
Cerebrospinal cytokine levels in patients with acute depression
-
DOI 10.1159/000026615
-
Levine J, Barak Y, Chengappa KN, Rapoport A, Rebey M, Barak V. Cerebrospinal cytokine levels in patients with acute depression. Neuropsychobiology 40(4), 171-176 (1999). (Pubitemid 29515729)
-
(1999)
Neuropsychobiology
, vol.40
, Issue.4
, pp. 171-176
-
-
Levine, J.1
Barak, Y.2
Chengappa, K.N.R.3
Rapoport, A.4
Rebey, M.5
Barak, V.6
-
43
-
-
0345130090
-
Interleukin-6 and the soluble IL-6 receptor are decreased in cerebrospinal fluid of geriatric patients with major depression: No alteration of soluble gp130
-
DOI 10.1016/S0304-3940(98)00916-1, PII S0304394098009161
-
Stubner S, Schon T, Padberg F, et al. Interleukin-6 and the soluble IL-6 receptor are decreased in cerebrospinal fluid of geriatric patients with major depression: no alteration of soluble gp130. Neurosci. Lett. 259(3), 145-148 (1999). (Pubitemid 29059605)
-
(1999)
Neuroscience Letters
, vol.259
, Issue.3
, pp. 145-148
-
-
Stubner, S.1
Schon, T.2
Padberg, F.3
Teipel, S.J.4
Schwarz, M.J.5
Haslinger, A.6
Buch, K.7
Dukoff, R.8
Lasser, R.9
Muller, N.10
Sunderland, T.11
Rapoport, S.I.12
Moller, H.-J.13
Hampel, H.14
-
44
-
-
1542719226
-
Cerebrospinal fluid interleukin (IL)-6 in unipolar major depression
-
DOI 10.1016/S0165-0327(02)00460-3, PII S0165032702004603
-
Carpenter LL, Heninger GR, Malison RT, Tyrka AR, Price LH. Cerebrospinal fluid interleukin (IL)-6 in unipolar major depression. J. Affect. Disord. 79(1-3), 285-289 (2004). (Pubitemid 38340558)
-
(2004)
Journal of Affective Disorders
, vol.79
, Issue.1-3
, pp. 285-289
-
-
Carpenter, L.L.1
Heninger, G.R.2
Malison, R.T.3
Tyrka, A.R.4
Price, L.H.5
-
45
-
-
67649406060
-
Interleukin-6 is elevated in the cerebrospinal fluid of suicide attempters and related to symptom severity
-
Lindqvist D, Janelidze S, Hagell P, et al. Interleukin-6 is elevated in the cerebrospinal fluid of suicide attempters and related to symptom severity. Biol. Psychiat. 66(3), 287-292 (2009).
-
(2009)
Biol. Psychiat.
, vol.66
, Issue.3
, pp. 287-292
-
-
Lindqvist, D.1
Janelidze, S.2
Hagell, P.3
-
46
-
-
58349113599
-
Activation of central nervous system inflammatory pathways by interferon-a: Relationship to monoamines and depression
-
Raison CL, Borisov AS, Majer M, et al. Activation of central nervous system inflammatory pathways by interferon-a: relationship to monoamines and depression. Biol. Psychiat. 65(4), 296-303 (2009).
-
(2009)
Biol. Psychiat.
, vol.65
, Issue.4
, pp. 296-303
-
-
Raison, C.L.1
Borisov, A.S.2
Majer, M.3
-
47
-
-
0031970243
-
Blood levels of cytokines in elderly patients with major depressive disorder
-
Brambilla F, Maggioni M. Blood levels of cytokines in elderly patients with major depressive disorder. Acta Psychiatrica Scand. 97(4), 309-313 (1998). (Pubitemid 28179269)
-
(1998)
Acta Psychiatrica Scandinavica
, vol.97
, Issue.4
, pp. 309-313
-
-
Brambilla, F.1
Maggioni, M.2
-
48
-
-
0032790648
-
Plasma levels of cytokines and soluble cytokine receptors in psychiatric patients upon hospital admission: Effects of confounding factors and diagnosis
-
DOI 10.1016/S0022-3956(99)00021-7, PII S0022395699000217
-
Haack M, Hinze-Selch D, Fenzel T, et al. Plasma levels of cytokines and soluble cytokine receptors in psychiatric patients upon hospital admission: effects of confounding factors and diagnosis. J. Psychiatr. Res. 33(5), 407-418 (1999). (Pubitemid 29392689)
-
(1999)
Journal of Psychiatric Research
, vol.33
, Issue.5
, pp. 407-418
-
-
Haack, M.1
Hinze-Selch, D.2
Fenzel, T.3
Kraus, T.4
Kuhn, M.5
Schuld, A.6
Pollmacher, T.7
-
49
-
-
0033975012
-
Cytokine production and treatment response in major depressive disorder
-
DOI 10.1016/S0893-133X(99)00134-7, PII S0893133X99001347
-
Lanquillon S, Krieg JC, Bening-Abu-Shach U, Vedder H. Cytokine production and treatment response in major depressive disorder. Neuropsychopharmacology 22(4), 370-379 (2000). (Pubitemid 30105765)
-
(2000)
Neuropsychopharmacology
, vol.22
, Issue.4
, pp. 370-379
-
-
Lanquillon, S.1
Krieg, J.-C.2
Bening-Abu-Shach, U.3
Vedder, H.4
-
50
-
-
0033924970
-
Plasma levels of interleukin-6, interleukin-10, and interleukin-1 receptor antagonist in depression: Comparison between the acute state and after remission
-
Kubera M, Kenis G, Bosmans E, et al. Plasma levels of interleukin-6, interleukin-10, and interleukin-1 receptor antagonist in depression: comparison between the acute state and after remission. Pol. J. Pharmacol. 52(3), 237-241 (2000). (Pubitemid 30479574)
-
(2000)
Polish Journal of Pharmacology
, vol.52
, Issue.3
, pp. 237-241
-
-
Kubera, M.1
Kenis, G.2
Bosmans, E.3
Zieba, A.4
Dudek, D.5
Nowak, G.6
Maes, M.7
-
51
-
-
0035128357
-
Plasma concentrations of interleukin-1β, interleukin-6, soluble interleukin-2 receptor and tumor necrosis factor α of depressed patients in Japan
-
DOI 10.1159/000054867
-
Kagaya A, Kugaya A, Takebayashi M, et al. Plasma concentrations of interleukin-1b, interleukin-6, soluble interleukin-2 receptor and tumor necrosis factor a of depressed patients in Japan. Neuropsychobiology 43(2), 59-62 (2001). (Pubitemid 32149726)
-
(2001)
Neuropsychobiology
, vol.43
, Issue.2
, pp. 59-62
-
-
Kagaya, A.1
Kugaya, A.2
Takebayashi, M.3
Fukue-Saeki, M.4
Saeki, T.5
Yamawaki, S.6
Uchitomi, Y.7
-
52
-
-
70349512465
-
Accuracy of cerebrospinal fluid IL-6 testing for diagnosis of lupus psychosis. A multicenter retrospective study
-
Hirohata S, Kanai Y, Mitsuo A, Tokano Y, Hashimoto H. Accuracy of cerebrospinal fluid IL-6 testing for diagnosis of lupus psychosis. A multicenter retrospective study. Clin. Rheumatol. 28(11), 1319-1323 (2009).
-
(2009)
Clin. Rheumatol.
, vol.28
, Issue.11
, pp. 1319-1323
-
-
Hirohata, S.1
Kanai, Y.2
Mitsuo, A.3
Tokano, Y.4
Hashimoto, H.5
-
53
-
-
34247271522
-
Interleukin-6 and chemokines in the neuropsychiatric manifestations of systemic lupus erythematosus
-
DOI 10.1002/art.22451
-
Fragoso-Loyo H, Richaud-Patin Y, Orozco-Narvaez A, et al. Interleukin-6 and chemokines in the neuropsychiatric manifestations of systemic lupus erythematosus. Arthritis Rheum. 56(4), 1242-1250 (2007). (Pubitemid 46608649)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.4
, pp. 1242-1250
-
-
Fragoso-Loyo, H.1
Richaud-Patin, Y.2
Orozco-Narvaez, A.3
Davila-Maldonado, L.4
Atisha-Fregoso, Y.5
Llorente, L.6
Sanchez-Guerrero, J.7
-
54
-
-
0034852467
-
Glutamate, interleukin-6, and early clinical worsening in patients with acute stroke
-
Vila N, Chamorro A, Castillo J, Davalos A. Glutamate, interleukin-6, and early clinical worsening in patients with acute stroke. Stroke 32(5), 1234-1237 (2001).
-
(2001)
Stroke
, vol.32
, Issue.5
, pp. 1234-1237
-
-
Vila, N.1
Chamorro, A.2
Castillo, J.3
Davalos, A.4
-
55
-
-
0027105095
-
Cerebrospinal fluid levels of IL-6 in patients with acute infections of the central nervous system
-
Torre D, Zeroli C, Ferraro G, et al. Cerebrospinal fluid levels of IL-6 in patients with acute infections of the central nervous system. Scand. J. Infect. Dis. 24(6), 787-791 (1992). (Pubitemid 23047112)
-
(1992)
Scandinavian Journal of Infectious Diseases
, vol.24
, Issue.6
, pp. 787-791
-
-
Torre, D.1
Zeroli, C.2
Ferraro, G.3
Speranza, F.4
Tambini, R.5
Martegani, R.6
Fiori, G.P.7
-
56
-
-
67349129131
-
S100B's double life: Intracellular regulator and extracellular signal
-
Donato R, Sorci G, Riuzzi F, et al. S100B's double life: intracellular regulator and extracellular signal. Biochim. Biophys. Acta 1793(6), 1008-1022 (2009).
-
(2009)
Biochim. Biophys. Acta
, vol.1793
, Issue.6
, pp. 1008-1022
-
-
Donato, R.1
Sorci, G.2
Riuzzi, F.3
-
57
-
-
6044238142
-
Glial cell dysfunction in schizophrenia indicated by increased S100B in the CSF [2]
-
DOI 10.1038/sj.mp.4001548
-
Rothermundt M, Falkai P, Ponath G, et al. Glial cell dysfunction in schizophrenia indicated by increased S100B in the CSF. Mol. Psychiatry 9(10), 897-899 (2004). (Pubitemid 39381953)
-
(2004)
Molecular Psychiatry
, vol.9
, Issue.10
, pp. 897-899
-
-
Rothermundt, M.1
Falkai, P.2
Ponath, G.3
Abel, S.4
Burkle, H.5
Diedrich, M.6
Hetzel, G.7
Peters, M.8
Siegmund, A.9
Pedersen, A.10
Maier, W.11
Schramm, J.12
Suslow, T.13
Ohrmann, P.14
Arolt, V.15
-
58
-
-
33750429912
-
Increased cerebrospinal fluid and serum levels of S100B in first-onset schizophrenia are not related to a degenerative release of glial fibrillar acidic protein, myelin basic protein and neurone-specific enolase from glia or neurones
-
DOI 10.1136/jnnp.2006.093427
-
Steiner J, Bielau H, Bernstein HG, Bogerts B, Wunderlich MT. Increased cerebrospinal fluid and serum levels of S100B in first-onset schizophrenia are not related to a degenerative release of glial fibrillar acidic protein, myelin basic protein and neurone-specific enolase from glia or neurones. J. Neurol. Neurosurg. Psychiatry 77(11), 1284-1287 (2006). (Pubitemid 44654765)
-
(2006)
Journal of Neurology, Neurosurgery and Psychiatry
, vol.77
, Issue.11
, pp. 1284-1287
-
-
Steiner, J.1
Bielau, H.2
Bernstein, H.-G.3
Bogerts, B.4
Wunderlich, M.T.5
-
59
-
-
41549164882
-
Cerebrospinal fluid: Identification of diagnostic markers for schizophrenia
-
DOI 10.1586/14737159.8.2.209
-
Schwarz E, Bahn S. Cerebrospinal fluid: identification of diagnostic markers for schizophrenia. Exp. Rev. Mol. Diagn. 8(2), 209-216 (2008). (Pubitemid 351469440)
-
(2008)
Expert Review of Molecular Diagnostics
, vol.8
, Issue.2
, pp. 209-216
-
-
Schwarz, E.1
Bahn, S.2
-
60
-
-
0032803360
-
CSF SNAP-25 in schizophrenia and bipolar illness. A pilot study
-
Thompson PM, Rosenberger C, Qualls C. CSF SNAP-25 in schizophrenia and bipolar illness. A pilot study. Neuropsychopharmacology 21(6), 717-722 (1999).
-
(1999)
Neuropsychopharmacology
, vol.21
, Issue.6
, pp. 717-722
-
-
Thompson, P.M.1
Rosenberger, C.2
Qualls, C.3
-
61
-
-
3843082950
-
GSK-3β in cerebrospinal fluid of schizophrenia patients
-
Kozlovsky N, Regenold WT, Levine J, Rapoport A, Belmaker RH, Agam G. GSK-3b in cerebrospinal fluid of schizophrenia patients. J. Neural Transm. 111(8), 1093-1098 (2004). (Pubitemid 39037129)
-
(2004)
Journal of Neural Transmission
, vol.111
, Issue.8
, pp. 1093-1098
-
-
Kozlovsky, N.1
Regenold, W.T.2
Levine, J.3
Rapoport, A.4
Belmaker, R.H.5
Agam, G.6
-
62
-
-
43149087350
-
Neuron-specific enolase and myelin basic protein in cerebrospinal fluid of patients with first episode schizophrenia
-
Li S, Wu H, Guo H, Zhao Z. Neuron-specific enolase and myelin basic protein in cerebrospinal fluid of patients with first episode schizophrenia. J. Huazhong Univ. Sci. Technol. Med. Sci. 26(2), 228-230 (2006).
-
(2006)
J. Huazhong Univ. Sci. Technol. Med. Sci.
, vol.26
, Issue.2
, pp. 228-230
-
-
Li, S.1
Wu, H.2
Guo, H.3
Zhao, Z.4
-
63
-
-
78650769933
-
N-(4-((2-(trifluoromethyl)-3-hydroxy-4- (isobutyryl)phenoxy)methyl) benzyl)- 1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: In vivo profiling suggests a link between behavioral and central nervous system neurochemical changes
-
Fell MJ, Witkin JM, Falcone JF, et al. N-(4-((2-(trifluoromethyl)-3- hydroxy-4- (isobutyryl)phenoxy)methyl)benzyl)- 1-methyl-1H-imidazole-4- carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a link between behavioral and central nervous system neurochemical changes. J. Pharmacol. Exp. Ther. 336(1), 165-177 (2011).
-
(2011)
J. Pharmacol. Exp. Ther.
, vol.336
, Issue.1
, pp. 165-177
-
-
Fell, M.J.1
Witkin, J.M.2
Falcone, J.F.3
-
64
-
-
65149094475
-
The discovery of a structurally novel class of inhibitors of the type 1 glycine transporter
-
Lowe JA 3rd, Hou X, Schmidt C, et al. The discovery of a structurally novel class of inhibitors of the type 1 glycine transporter. Bioorg. Med. Chem. Lett. 19(11), 2974-2976 (2009).
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, Issue.11
, pp. 2974-2976
-
-
Lowe Iii., J.A.1
Hou, X.2
Schmidt, C.3
-
65
-
-
33845308197
-
Disease biomarkers in cerebrospinal fluid of patients with first-onset psychosis
-
Huang JT, Leweke FM, Oxley D, et al. Disease biomarkers in cerebrospinal fluid of patients with first-onset psychosis. PLoS Med. 3(11), e428 (2006).
-
(2006)
PLoS Med.
, vol.3
, Issue.11
-
-
Huang, J.T.1
Leweke, F.M.2
Oxley, D.3
-
66
-
-
39749171224
-
CSF metabolic and proteomic profiles in patients prodromal for psychosis
-
Huang JT, Leweke FM, Tsang TM, et al. CSF metabolic and proteomic profiles in patients prodromal for psychosis. PLoS One 2(8), e756 (2007).
-
(2007)
PLoS One
, vol.2
, Issue.8
-
-
Huang, J.T.1
Leweke, F.M.2
Tsang, T.M.3
-
67
-
-
79955431733
-
Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis
-
Craig-Schapiro R, Kuhn M, Xiong C, et al. Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis. PLoS One 6(4), e18850 (2011).
-
(2011)
PLoS One
, vol.6
, Issue.4
-
-
Craig-Schapiro, R.1
Kuhn, M.2
Xiong, C.3
-
68
-
-
77955483685
-
Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects
-
Trojanowski JQ, Vandeerstichele H, Korecka M, et al. Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects. Alzheimers Dement. 6(3), 230-238 (2010).
-
(2010)
Alzheimers Dement.
, vol.6
, Issue.3
, pp. 230-238
-
-
Trojanowski, J.Q.1
Vandeerstichele, H.2
Korecka, M.3
-
70
-
-
0032694577
-
'Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
-
Nicholson JK, Lindon JC, Holmes E. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 29(11), 1181-1189 (1999).
-
(1999)
Xenobiotica
, vol.29
, Issue.11
, pp. 1181-1189
-
-
Nicholson, J.K.1
Lindon, J.C.2
Holmes, E.3
-
71
-
-
33748354488
-
Metabolic profiling of CSF: Evidence that early intervention may impact on disease progression and outcome in schizophrenia
-
Holmes E, Tsang TM, Huang JT, et al. Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia. PLoS Med. 3(8), e327 (2006).
-
(2006)
PLoS Med.
, vol.3
, Issue.8
-
-
Holmes, E.1
Tsang, T.M.2
Huang, J.T.3
-
72
-
-
2342562466
-
Mitochondria, synaptic plasticity, and schizophrenia
-
DOI 10.1016/S0074-7742(04)59011-6, PII S0074774204590116
-
Ben-Shachar D, Laifenfeld D. Mitochondria, synaptic plasticity, and schizophrenia. Int. Rev. Neurobiol. 59, 273-296 (2004). (Pubitemid 39752419)
-
(2004)
International Review of Neurobiology
, vol.59
, pp. 273-296
-
-
Ben-Shachar, D.1
Laifenfeld, D.2
-
73
-
-
0034280096
-
Mitochondrial dysfunction in bipolar disorder
-
Kato T, Kato N. Mitochondrial dysfunction in bipolar disorder. Bipolar Disord. 2(3 Pt 1), 180-190 (2000).
-
(2000)
Bipolar Disord.
, vol.2
, Issue.3 PART 1
, pp. 180-190
-
-
Kato, T.1
Kato, N.2
-
74
-
-
51749121067
-
Mitochondrially mediated plasticity in the pathophysiology and treatment of bipolar disorder
-
Quiroz JA, Gray NA, Kato T, Manji HK. Mitochondrially mediated plasticity in the pathophysiology and treatment of bipolar disorder. Neuropsychopharmacology 33(11), 2551-2565 (2008).
-
(2008)
Neuropsychopharmacology
, vol.33
, Issue.11
, pp. 2551-2565
-
-
Quiroz, J.A.1
Gray, N.A.2
Kato, T.3
Manji, H.K.4
-
75
-
-
64249162752
-
Mitochondrial dysfunction and psychiatric disorders
-
Rezin GT, Amboni G, Zugno AI, Quevedo J, Streck EL. Mitochondrial dysfunction and psychiatric disorders. Neurochem. Res. 34(6), 1021-1029 (2009).
-
(2009)
Neurochem. Res.
, vol.34
, Issue.6
, pp. 1021-1029
-
-
Rezin, G.T.1
Amboni, G.2
Zugno, A.I.3
Quevedo, J.4
Streck, E.L.5
-
76
-
-
60349098146
-
Elevated cerebrospinal fluid lactate concentrations in patients with bipolar disorder and schizophrenia: Implications for the mitochondrial dysfunction hypothesis
-
Regenold WT, Phatak P, Marano CM, Sassan A, Conley RR, Kling MA. Elevated cerebrospinal fluid lactate concentrations in patients with bipolar disorder and schizophrenia: implications for the mitochondrial dysfunction hypothesis. Biol. Psychiatry 65(6), 489-494 (2009).
-
(2009)
Biol. Psychiatry
, vol.65
, Issue.6
, pp. 489-494
-
-
Regenold, W.T.1
Phatak, P.2
Marano, C.M.3
Sassan, A.4
Conley, R.R.5
Kling, M.A.6
-
77
-
-
77955768646
-
Proteomic investigations of the ventriculo-lumbar gradient in human CSF
-
Simonsen AH, Bech S, Laursen I, et al. Proteomic investigations of the ventriculo-lumbar gradient in human CSF. J. Neurosci. Methods 191(2), 244-248 (2010).
-
(2010)
J. Neurosci. Methods
, vol.191
, Issue.2
, pp. 244-248
-
-
Simonsen, A.H.1
Bech, S.2
Laursen, I.3
-
78
-
-
79954420818
-
Rostrocaudal dynamics of CSF biomarkers
-
Tarnaris A, Toma AK, Chapman MD, et al. Rostrocaudal dynamics of CSF biomarkers. Neurochem. Res. 36(3), 528-532 (2011).
-
(2011)
Neurochem. Res.
, vol.36
, Issue.3
, pp. 528-532
-
-
Tarnaris, A.1
Toma, A.K.2
Chapman, M.D.3
-
79
-
-
65249159879
-
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
-
Shaw LM, Vanderstichele H, Knapik-Czajka M, et al. Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects. Ann. Neurol. 65(4), 403-413 (2009).
-
(2009)
Ann. Neurol.
, vol.65
, Issue.4
, pp. 403-413
-
-
Shaw, L.M.1
Vanderstichele, H.2
Knapik-Czajka, M.3
|