메뉴 건너뛰기




Volumn 33, Issue 2, 2009, Pages 214-219

The leukocytes expressing DARPP-32 are reduced in patients with schizophrenia and bipolar disorder

Author keywords

Bipolar disorder; DARPP 32; Dopamine; Flow cytometry; Leukocytes; Peripheral blood mononuclear cells (PBMC); Schizophrenia

Indexed keywords

BIOLOGICAL MARKER; CD14 ANTIGEN; CD19 ANTIGEN; CD56 ANTIGEN; CYCLIC AMP; DOPAMINE; MESSENGER RNA; PHOSPHOPROTEIN DARPP 32;

EID: 60249102897     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2008.10.020     Document Type: Article
Times cited : (45)

References (43)
  • 2
    • 12244286806 scopus 로고    scopus 로고
    • High numbers of circulating activated T cells and raised levels of serum IL-2 receptor in bipolar disorder
    • Breunis M.N., Kupka R.W., Nolen W.A., Suppes T., Denicoff K.D., Leverich G.S., et al., Drexhage H.A. High numbers of circulating activated T cells and raised levels of serum IL-2 receptor in bipolar disorder. Biol Psychiatry 53 (2003) 157-165
    • (2003) Biol Psychiatry , vol.53 , pp. 157-165
    • Breunis, M.N.1    Kupka, R.W.2    Nolen, W.A.3    Suppes, T.4    Denicoff, K.D.5    Leverich, G.S.6
  • 3
    • 0026348479 scopus 로고
    • Reduced natural killer cell cytotoxicity in depression but not in schizophrenia
    • Caldwell C.L., Irwin M., and Lohr J. Reduced natural killer cell cytotoxicity in depression but not in schizophrenia. Biol Psychiatry 30 (1991) 1131-1138
    • (1991) Biol Psychiatry , vol.30 , pp. 1131-1138
    • Caldwell, C.L.1    Irwin, M.2    Lohr, J.3
  • 5
    • 33646841343 scopus 로고    scopus 로고
    • Genomic profiles for human peripheral blood T cells, B cells, natural killer cells, monocytes, and polymorphonuclear cells: comparisons to ischemic stroke, migraine, and Tourette syndrome
    • Du X., Tang Y., Xu H., Lit L., Walker W., Ashwood P., et al. Genomic profiles for human peripheral blood T cells, B cells, natural killer cells, monocytes, and polymorphonuclear cells: comparisons to ischemic stroke, migraine, and Tourette syndrome. Genomics 87 (2006) 693-703
    • (2006) Genomics , vol.87 , pp. 693-703
    • Du, X.1    Tang, Y.2    Xu, H.3    Lit, L.4    Walker, W.5    Ashwood, P.6
  • 6
    • 0842310838 scopus 로고    scopus 로고
    • Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia
    • Emamian E.S., Hall D., Birnbaum M.J., Karayiorgou M., and Gogos J.A. Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia. Nat Genet 36 (2004) 131-137
    • (2004) Nat Genet , vol.36 , pp. 131-137
    • Emamian, E.S.1    Hall, D.2    Birnbaum, M.J.3    Karayiorgou, M.4    Gogos, J.A.5
  • 7
    • 0023626250 scopus 로고
    • Clinical and laboratory evidence of autoimmunity in acute schizophrenia
    • Ganguli R., Rabin B.S., Kelly R.H., Lyte M., and Ragu U. Clinical and laboratory evidence of autoimmunity in acute schizophrenia. Ann N Y Acad Sci 496 (1987) 676-685
    • (1987) Ann N Y Acad Sci , vol.496 , pp. 676-685
    • Ganguli, R.1    Rabin, B.S.2    Kelly, R.H.3    Lyte, M.4    Ragu, U.5
  • 8
    • 28844471630 scopus 로고    scopus 로고
    • Typical and atypical antipsychotics in bipolar depression
    • Gao K., Gajwani P., Elhaj O., and Calabrese J.R. Typical and atypical antipsychotics in bipolar depression. J Clin Psychiatry 66 (2005) 1376-1385
    • (2005) J Clin Psychiatry , vol.66 , pp. 1376-1385
    • Gao, K.1    Gajwani, P.2    Elhaj, O.3    Calabrese, J.R.4
  • 9
    • 33644865256 scopus 로고    scopus 로고
    • Mucosal leishmaniasis patients display an activated inflammatory T-cell phenotype associated with a nonbalanced monocyte population
    • Gaze S.T., Dutra W.O., Lessa M., Lessa H., Guimarães L.H., Jesus A.R., et al. Mucosal leishmaniasis patients display an activated inflammatory T-cell phenotype associated with a nonbalanced monocyte population. Scand J Immunol 63 (2006) 70-78
    • (2006) Scand J Immunol , vol.63 , pp. 70-78
    • Gaze, S.T.1    Dutra, W.O.2    Lessa, M.3    Lessa, H.4    Guimarães, L.H.5    Jesus, A.R.6
  • 12
    • 0025332801 scopus 로고
    • Chronic treatment of rats with SCH-23390 or raclopride does not affect the concentrations of DARPP-32 or its mRNA in dopamine-innervated brain regions
    • Grebb J.A., Girault J.A., Ehrlich M., and Greengard P. Chronic treatment of rats with SCH-23390 or raclopride does not affect the concentrations of DARPP-32 or its mRNA in dopamine-innervated brain regions. J Neurochem 55 (1990) 204-207
    • (1990) J Neurochem , vol.55 , pp. 204-207
    • Grebb, J.A.1    Girault, J.A.2    Ehrlich, M.3    Greengard, P.4
  • 13
    • 0026733192 scopus 로고
    • Chronic administration of lithium or other antidepressants increases levels of DARPP-32 in rat frontal cortex
    • Guitart X., and Nestler E.J. Chronic administration of lithium or other antidepressants increases levels of DARPP-32 in rat frontal cortex. J Neurochem 59 (1992) 1164-1167
    • (1992) J Neurochem , vol.59 , pp. 1164-1167
    • Guitart, X.1    Nestler, E.J.2
  • 16
    • 33646818313 scopus 로고    scopus 로고
    • Mechanism of action of atypical antipsychotic drugs and the neurobiology of schizophrenia
    • Horacek J., Bubenikova-Valesova V., Kopecek M., Palecinek T., Dockery C., Mohr P., et al. Mechanism of action of atypical antipsychotic drugs and the neurobiology of schizophrenia. CNS Drugs 20 (2006) 389-409
    • (2006) CNS Drugs , vol.20 , pp. 389-409
    • Horacek, J.1    Bubenikova-Valesova, V.2    Kopecek, M.3    Palecinek, T.4    Dockery, C.5    Mohr, P.6
  • 17
    • 0033583138 scopus 로고    scopus 로고
    • Characterization of the inhibition of protein phosphatase-1 by DARPP-32 and inhibitor-2
    • Huang H.B., Horiuchi A., Watanabe T., Shih S.R., Tsay H.J., Li H.C., et al. Characterization of the inhibition of protein phosphatase-1 by DARPP-32 and inhibitor-2. J Biol Chem 274 (1999) 7870-7878
    • (1999) J Biol Chem , vol.274 , pp. 7870-7878
    • Huang, H.B.1    Horiuchi, A.2    Watanabe, T.3    Shih, S.R.4    Tsay, H.J.5    Li, H.C.6
  • 18
    • 34447570721 scopus 로고    scopus 로고
    • Immunohistochemical and immunoblot analysis of Dopamine and cyclic AMP-regulated phosphoprotein, relative molecular mass 32,000 (DARPP-32) in the prefrontal cortex of subjects with schizophrenia and bipolar disorder
    • Ishikawa M., Mizukami K., Iwakiri M., and Asada T. Immunohistochemical and immunoblot analysis of Dopamine and cyclic AMP-regulated phosphoprotein, relative molecular mass 32,000 (DARPP-32) in the prefrontal cortex of subjects with schizophrenia and bipolar disorder. Prog Neuro-psychopharmacol. Biol. Psychiatry 31 (2007) 1177-1181
    • (2007) Prog Neuro-psychopharmacol. Biol. Psychiatry , vol.31 , pp. 1177-1181
    • Ishikawa, M.1    Mizukami, K.2    Iwakiri, M.3    Asada, T.4
  • 19
    • 20344374645 scopus 로고    scopus 로고
    • Prevalence, severity, and comorbidity of twelve-month DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R)
    • Kessler R.C., Chiu W.T., and Demler O. Prevalence, severity, and comorbidity of twelve-month DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R). Arch Gen Psychiatry 62 (2005) 617-627
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 617-627
    • Kessler, R.C.1    Chiu, W.T.2    Demler, O.3
  • 22
    • 0034666355 scopus 로고    scopus 로고
    • Signaling: cellular insights into pathophysiology of bipolar disorder
    • Manji H.K., and Lenox R.H. Signaling: cellular insights into pathophysiology of bipolar disorder. Biol Psychiatry 48 (2000) 518-530
    • (2000) Biol Psychiatry , vol.48 , pp. 518-530
    • Manji, H.K.1    Lenox, R.H.2
  • 23
    • 0042130064 scopus 로고    scopus 로고
    • Cognitive and symptom predictors of work outcomes for clients with schizophrenia in supported employment
    • McGurk S.R., Mueser K.T., Harvey P.D., LaPuglia R., and Marder J. Cognitive and symptom predictors of work outcomes for clients with schizophrenia in supported employment. Psychiatr Serv 54 (2003) 1129-1135
    • (2003) Psychiatr Serv , vol.54 , pp. 1129-1135
    • McGurk, S.R.1    Mueser, K.T.2    Harvey, P.D.3    LaPuglia, R.4    Marder, J.5
  • 24
    • 21244460815 scopus 로고    scopus 로고
    • Close encounters of the monoamine kind: immune cells betray their nervous disposition
    • Meredith E.J., Chamba A., Holder M.J., Barnes N.M., and Gordon J. Close encounters of the monoamine kind: immune cells betray their nervous disposition. Immunology 115 (2005) 289-295
    • (2005) Immunology , vol.115 , pp. 289-295
    • Meredith, E.J.1    Chamba, A.2    Holder, M.J.3    Barnes, N.M.4    Gordon, J.5
  • 25
    • 0018425438 scopus 로고
    • A new depression scale designed to be sensitive to change
    • Montgomery S.A., and Asberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry 134 (1979) 382-389
    • (1979) Br J Psychiatry , vol.134 , pp. 382-389
    • Montgomery, S.A.1    Asberg, M.2
  • 27
    • 0343396440 scopus 로고    scopus 로고
    • Increased frequency of activated lymphocytes in the cerebrospinal fluid of patients with acute schizophrenia
    • Nikkila H.V., Muller K., Ahokas A., Rimon R., and Andersson L.C. Increased frequency of activated lymphocytes in the cerebrospinal fluid of patients with acute schizophrenia. Schizophr Res 49 (2001) 99-105
    • (2001) Schizophr Res , vol.49 , pp. 99-105
    • Nikkila, H.V.1    Muller, K.2    Ahokas, A.3    Rimon, R.4    Andersson, L.C.5
  • 28
    • 0030831116 scopus 로고    scopus 로고
    • Bidirectional regulation of DARPP-32 phosphorylation by dopamine
    • Nishi A., Snyder G.L., and Greengard P. Bidirectional regulation of DARPP-32 phosphorylation by dopamine. J Neurosci 17 (1997) 8147-8155
    • (1997) J Neurosci , vol.17 , pp. 8147-8155
    • Nishi, A.1    Snyder, G.L.2    Greengard, P.3
  • 29
    • 34347345956 scopus 로고    scopus 로고
    • Dopamine transporter immunoreactivity in peripheral blood lymphocytes discriminates Parkinson's disease from essential tremor
    • Pellicano C., Buttarelli F.R., Circella A., Tiple D., Giovannelli M., Benincasa D., et al. Dopamine transporter immunoreactivity in peripheral blood lymphocytes discriminates Parkinson's disease from essential tremor. J Neural Transm 114 (2007) 935-938
    • (2007) J Neural Transm , vol.114 , pp. 935-938
    • Pellicano, C.1    Buttarelli, F.R.2    Circella, A.3    Tiple, D.4    Giovannelli, M.5    Benincasa, D.6
  • 32
    • 0022570609 scopus 로고
    • Studies of cellular immunity, serum interferon titers, and natural killer cell activity in schizophrenic patients
    • Schindler L., Leroux M., Beck J., Moises H.W., and Kirchner H. Studies of cellular immunity, serum interferon titers, and natural killer cell activity in schizophrenic patients. Acta Psychiatr Scand 73 (1986) 651-657
    • (1986) Acta Psychiatr Scand , vol.73 , pp. 651-657
    • Schindler, L.1    Leroux, M.2    Beck, J.3    Moises, H.W.4    Kirchner, H.5
  • 37
    • 0033609544 scopus 로고    scopus 로고
    • T-cell subsets in schizophrenia: a comparison between drug-naive first episode patients and chronic schizophrenic patients
    • Sperner-Unterweger B., Whitworth A., Kemmler G., Hilbe W., Thaler J., Weiss G., et al. T-cell subsets in schizophrenia: a comparison between drug-naive first episode patients and chronic schizophrenic patients. Schizophr Res 38 (1999) 61-70
    • (1999) Schizophr Res , vol.38 , pp. 61-70
    • Sperner-Unterweger, B.1    Whitworth, A.2    Kemmler, G.3    Hilbe, W.4    Thaler, J.5    Weiss, G.6
  • 38
    • 0034652091 scopus 로고    scopus 로고
    • Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors
    • Svenningsson P., Lindskog M., Ledent C., Parmentier M., Greengard P., Fredholm B.B., et al. Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors. Proc Natl Acad Sci U S A 97 (2000) 1856-1860
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1856-1860
    • Svenningsson, P.1    Lindskog, M.2    Ledent, C.3    Parmentier, M.4    Greengard, P.5    Fredholm, B.B.6
  • 40
    • 23044490894 scopus 로고    scopus 로고
    • Norepinephrine, dopamine and dexamethasone modulate discrete leukocyte subpopulations and cytokine profiles from human PBMC
    • Torres K.C., Antonelli L.R., Souza A.L., Teixeira M.M., Dutra W.O., and Gollob K.J. Norepinephrine, dopamine and dexamethasone modulate discrete leukocyte subpopulations and cytokine profiles from human PBMC. J Neuroimmunol 166 (2005) 144-157
    • (2005) J Neuroimmunol , vol.166 , pp. 144-157
    • Torres, K.C.1    Antonelli, L.R.2    Souza, A.L.3    Teixeira, M.M.4    Dutra, W.O.5    Gollob, K.J.6
  • 41
    • 36148955383 scopus 로고    scopus 로고
    • Dopamine in drug abuse and addiction: results of imaging studies and treatment implications
    • Volkow N.D., Fowler J.S., Wang G.J., Swanson J.M., and Telang F. Dopamine in drug abuse and addiction: results of imaging studies and treatment implications. Arch Neurol 64 (2007) 1575-1579
    • (2007) Arch Neurol , vol.64 , pp. 1575-1579
    • Volkow, N.D.1    Fowler, J.S.2    Wang, G.J.3    Swanson, J.M.4    Telang, F.5
  • 42
    • 0038266756 scopus 로고    scopus 로고
    • Chlorpromazine equivalent doses for the newer atypical antipsychotics
    • Woods S.W. Chlorpromazine equivalent doses for the newer atypical antipsychotics. J Clin Psychiatry 64 (2003) 663-667
    • (2003) J Clin Psychiatry , vol.64 , pp. 663-667
    • Woods, S.W.1
  • 43
    • 0018175277 scopus 로고
    • A rating scale for mania: reliability, validity and sensitivity
    • Young R.C., Biggs J.T., Ziegler V.E., and Meyer D.A. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry 133 (1978) 429-435
    • (1978) Br J Psychiatry , vol.133 , pp. 429-435
    • Young, R.C.1    Biggs, J.T.2    Ziegler, V.E.3    Meyer, D.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.