2B4 (CD244) is involved in eosinophil adhesion and chemotaxis, and its surface expression is increased in allergic rhinitis after challenge

International Journal of Immunopathology and Pharmacology

Volumn 24, Issue 4, 2011, Pages 949-960

  El Shazly, A E ^a   Henket, M ^a   Lefebvre, P P ^a   Louis, R ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

2B4 (CD244); Adhesion; Allergic rhinitis; CD2; Chemotaxis; Eol 1; Eosinophils; Tyrosine kinase

Indexed keywords

ALLERGEN; ANTIBODY; CD244 ANTIBODY; CHEMOKINE RECEPTOR CCR3; COLLAGEN TYPE 4; EOTAXIN; GENISTEIN; NEUTRALIZING ANTIBODY; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; HERMES ANTIGEN;

ALLERGIC RHINITIS; ARTICLE; BLOOD; CELL ADHESION; CELL LINE; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; CYTOSKELETON; EOSINOPHIL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO STUDY; MOLECULAR WEIGHT; NOSE PROVOCATION TEST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; CONFOCAL MICROSCOPY; ENZYME PHOSPHORYLATION; EOSINOPHIL ADHESION; EOSINOPHIL CHEMOTAXIS; IMMUNOFLUORESCENCE; LEUKOCYTE ADHERENCE; NEUTROPHIL CHEMOTAXIS; PROVOCATION TEST;

EID: 84856564784     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463201102400413     Document Type: Article

References (31)

1. Coyle AJ, Gutierrez-Ramos JC. The expanding B7 superfamily. increasing complexity in costimulatorty signals regulating T cell function. Nat Immunol 2001; 2:203-209. (Pubitemid 33705995)
2. Carreno BM, Collins M. The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Ann Rev Immunol 2002; 20:29-53. (Pubitemid 34293419)
3. SA Quezada, LZ Jarvinen, EF Lind, et al. CD40/CD154 interactions at interface of tolerance and immunity. Ann Rev Immunol 2004; 22:307-28. (Pubitemid 38680425)
4. Engel P, Eck MJ, Terhorst C. The SAP and SLAM families in immune responses and X-linked lymphoproliferative disease. Nat Rev Immunol 2003; 3:813-21. (Pubitemid 37328659)
5. Mathew PA, Garni-Wagner BA, Land K, et al. Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells. J Immunol 1993; 151:5328-37. (Pubitemid 23332342)
6. Valiante NM, Trinchieri G. Identification of a novel signal transduction surface molecule on human cytotoxic lymphocytes. J Exp Med 1993; 178:1397-406. (Pubitemid 23277371)
7. Veillette A, Latour S. The SLAM family of immune-cell receptors. Curr Opin Immunol 2003; 15:277-85. (Pubitemid 36645103)
8. Nakajima H, Cella M, Langen H, et al. Activating interactions in human NK cell recognition: the role of 2B4-CD48. Eur J Immunol 1999; 29:1676-83. (Pubitemid 29224473)
9. Boles KS, Nakajima H, Colonna M, et al. Molecular characterization of a novel human natural cell receptor homologous to mouse 2B4. Tissue Antigens 1999; 54:27-34. (Pubitemid 29326927)
10. Romero X, Benitez D, March S, et al. Differential expression of SAP and EAT-2 binding leukocyte cell-surface molecules CD48, CD 150 (SLAM), CD229 (Ly9) and CD244 (2B4). Tissue Antigens 2004; 64:132-44. (Pubitemid 38969577)
11. Latchman Y, Mckay PF, Reiser H. Identification of the 2B4 molecule as a counter-receptor for CD48. J Immunol 1998; 161:5809-12. (Pubitemid 28535943)
12. Brown MH, Boles K, van der Merwe PA, et al. 2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48. J Exp Med 1998; 188:2083-90. (Pubitemid 28562525)
13. Munitz A, Bachelet I, Eliashar R, et al. CD48 is an allergen and IL-13-induced activation molecule on eosinophils. J Immunol 2006; 177:77-83. (Pubitemid 43939118)
14. Munitz A, Bachelet I, Finkelman FD, et al. CD48 is critically involved in allergic eosinophilic airway inflammation. Am J Respir Crit Care Med 2007; 175:911-18. (Pubitemid 46684701)
15. Munitz A, Bachelet I, Fraenkel S, et al. 2B4 (CD244) is expressed and functional on human eosinophils. J Immunol 2005; 174:110-18. (Pubitemid 40007397)
16. Weiler PF. Eosinophilia. J Allergy Clin Immunol 1984; 73:1-14.
17. Ponath PD, Qin S, Ringler DJ, et al. Cloning of the human eosinophil chemoattractant, eotaxin expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils. J Clin Invest 1996; 97:604-12. (Pubitemid 26057077)
18. Ponath PD, Qin S, Post TW, et al. Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils. J Exp Med 1996; 183:2437-48. (Pubitemid 26192353)
19. Gracia-Zepeda EA, Rothenberg ME, Ownbey RT, et al. Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nature Med 1996; 2:449-56. (Pubitemid 26193013)
20. Lalaker A, Nkrumah L, Lee WK, et al. Chitin stimulates expression of acidic mammalian chitinase and eotaxin-3 by human sinonasal epithelial cells in vitro. Am J Rhinol Allergy 2009; 23:8-14.
21. Yu Z, Sun B, Kantarjian HM, et al. Protein expression profiling of cytokines and cytokine receptors on purified chronic lymphocytic leukemia cells from patients with favourable prognostic indicators. Leuk Lymphoma 2008; 49:751-56. (Pubitemid 351517221)
22. Yoshida N, Aizu-Yokota E, Sonoda Y, et al. Production and regulation of eotaxin-2/CCL24 in a differentiated human leukemic cell line, HT93. Biol Pharm Bull 2007; 30:1826-32. (Pubitemid 47607761)
23. Ishihara K, Takahashi A, Kaneko M, et al. Differentiation of eosinophilic leukemia Eol-1 cells into eosinophils induced by histone deacetylase inhibitors. Life Sciences 2001; 80:1213-20.
24. El-Shazly A, Berger P, Girodet P, et al. Fraktalkine produced by airway smooth muscle cells contributes to mast cell recruitment in asthma. J Immunol 2006; 176:1860-68. (Pubitemid 43134331)
25. El-Shazly A, Yamaguchi N, Masuyama K, et al. Novel association of the Src family kinases, Hck and c-Fgr, with CCR3 receptor stimulation: a possible mechanism for eotaxin-induced human eosinophil chemotaxis. Bioch Biophys Res Commun 1999; 264:163-70. (Pubitemid 29500481)
26. El-Shazly A, Keisuke M, Eura M, et al. Mechanisms involved in human eosinophil chemotaxis induced by the newly cloned C-C chemokine eotaxin. Allergol Int 1998; 47:49-12.
27. Campo PMH, Almeida J, Sanchez ML, et al. Normal patterns of expression of glycosylphosphatidyl linositol-anchored proteins on different subsets of peripheral blood cells : a frame of reference for the diagnosis of paroxysmal nocturnal haemoglobinuria. Cytometry part B (Clinical cytometry) 2006; 70B:71-81.
28. Ridley AJ, Schwartz MA, Burridge K, et al. Cell migration: integrating signals from front to back. Science 2003; 302:1704-09. (Pubitemid 37505725)
29. Kiema T, Lad Y, Jiang P, Oxley CL, et al. The molecular basis of filamin binding to integrins and competition with talin. Mol Cell 2006; 21:337-47. (Pubitemid 43163529)
30. Chen R, Relouzat F, Roncagalli R, et al. Molecular dissection of 2B4 signaling: implications for signal transduction by SLAM-related receptors. Mol Cell Biol 2004; 24:5144-56. (Pubitemid 38738152)
31. Eissmann P, Beauchamp L, Wooters J, et al. Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244). Blood 2005; 105:4722-29. (Pubitemid 40807295)