Protein expression profiling of cytokines and cytokine receptors on purified chronic lymphocytic leukemia cells from patients with favourable prognostic indicators

Leukemia and Lymphoma

Volumn 49, Issue 4, 2008, Pages 751-756

  Yu, Zhifeng ^a   Sun, Baohua ^a   Kantarjian, Hagop M ^a   Keating, Michael J ^a   Amin, Hesham M ^a   Sun, Xiaoping ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

CLL; Cytokine; Cytokine and chemokine biology; Cytokine production and paraneoplastic conditions; Hematopoiesis; IL 6; Immunobiology; Lymphocytes; Neoplasia

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR; EOTAXIN; INTERLEUKIN 6;

ADULT; AGED; B CELL LEUKEMIA; B LYMPHOCYTE; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

ADULT; AGED; B-LYMPHOCYTES; CASE-CONTROL STUDIES; CELLS, CULTURED; CHEMOKINE CCL11; CYTOKINES; FEMALE; HUMANS; INTERLEUKIN-6; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; MIDDLE AGED; PROGNOSIS; PROTEOMICS; RECEPTORS, CYTOKINE;

EID: 42049105207     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.1080/10428190801888696     Document Type: Conference Paper

References (32)

1. Carney, D. A. and Wierda, W. G. (2005) Genetics and molecular biology of chronic lymphocytic leukemia. Curr Treat Options Oncol, 6, pp. 215-225.
2. Rai, K. R. (2007) Pathophysiologic mechanisms of chronic lymphocytic leukemia and their application to therapy. Exp Hematol, 35, pp. 134-136.
3. Ghia, P., Circosta, P., Scielzo, C., Vallario, A., Camporeale, A., Granziero, L. and Caligaris-Cappio, F. (2005) Differential effects on CLL cell survival exerted by different microenvironmental elements. Curr Top Microbiol Immunol, 294, pp. 135-145.
4. Pedersen, I Munk and Reed, J. (2004) Microenvironmental interactions and survival of CLL B-cells. Leuk Lymphoma, 45, pp. 2365-2372.
5. Shanafelt, T. D. and Kay, N. E. (2006) The clinical and biologic importance of neovascularization and angiogenic signaling pathways in chronic lymphocytic leukemia. Semin Oncol, 33, pp. 174-185.
6. Kay, N. E., Shanafelt, T. D., Strege, A. K., Lee, Y. K., Bone, N. D. and Raza, A. (2007) Bone biopsy derived marrow stromal elements rescue chronic lymphocytic leukemia B-cells from spontaneous and drug induced cell death and facilitates an "angiogenic switch.". Leuk Res, 31, pp. 899-906.
7. Buschle, M., Campana, D., Carding, S. R., Richard, C., Hoffbrand, A. V. and Brenner, M. K. (1993) Interferon γ inhibits apoptotic cell death in B cell chronic lymphocytic leukemia. J Exp Med, 177, pp. 213-218.
8. Cordingley, F. T., Bianchi, A., Hoffbrand, A. V., Reittie, J. E., Heslop, H. E. and Vyakarnam, A. (1988) Tumour necrosis factor as an autocrine tumour growth factor for chronic B-cell malignancies. Lancet, 1, pp. 969-971.
9. Dancescu, M., Rubio-Trujillo, M., Biron, G., Bron, D., Delespesse, G. and Sarfati, M. (1992) Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and upregulates Bcl-2 expression. J Exp Med, 176, pp. 1319-1326.
10. Larsson, L. G., Carlsson, M., Schena, M., Lantz, M., Caligaris-Cappio, F. and Nilsson, K. (1993) Interleukin-2 enhances the production of tumor necrosis factor-α in activated B-type chronic lymphocytic leukemia (B-CLL) cells. Leukemia, 7, pp. 226-234.
11. Aderka, D., Maor, Y., Novick, D., Engelmann, H., Kahn, Y. and Levo, Y. (1993) Interleukin-6 inhibits the proliferation of B-chronic lymphocytic leukemia cells that is induced by tumor necrosis factor-α or -β. Blood, 81, pp. 2076-2084.
12. Tangye, S. G., Weston, K. M. and Raison, R. L. (1998) Interleukin-10 inhibits the in vitro proliferation of human activated leukemic CD5+ B-cells. Leuk Lymphoma, 31, pp. 121-130.
13. Barcellini, W., Montesano, R., Clerici, G., Zaninoni, A., Imperiali, F. G. and Calori, R. (2002) In vitro production of anti-RBC antibodies and cytokines in chronic lymphocytic leukemia. Am J Hematol, 71, pp. 177-183.
14. Mainou-Fowler, T., Proctor, S. J., Miller, S. and Dickinson, A. M. (2001) Expression and production of interleukin 4 in B-cell chronic lymphocytic leukaemia. Leuk Lymphoma, 42, pp. 689-698.
15. Jansen, J. H., Wientjens, G. J., Willemze, R. and Kluin-Nelemans, J. C. (1992) Production of tumor necrosis factor-α by normal and malignant B lymphocytes in response to interferon-α, interferon-β and interleukin-4. Leukemia, 6, pp. 116-119.
16. Foa, R., Massaia, M., Cardona, S., Tos, A. G., Bianchi, A. and Attisano, C. (1990) Production of tumor necrosis factor-α by B-cell chronic lymphocytic leukemia cells: A possible regulatory role of TNF in the progression of the disease. Blood, 76, pp. 393-400.
17. Wognum, A. W., Lansdorp, P. M., Humphries, R. K. and Krystal, G. (1990) Detection and isolation of the erythropoietin receptor using biotinylated erythropoietin. Blood, 76, pp. 697-705.
18. Damle, R. N., Wasil, T., Fais, F., Ghiotto, F., Valetto, A. and Allen, S. L. (1999) Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood, 94, pp. 1840-1847.
19. Admirand, J. H., Rassidakis, G. Z., Abruzzo, L. V., Valbuena, J. R., Jones, D. and Medeiros, L. J. (2004) Immunohistochemical detection of ZAP-70 in 341 cases of non-Hodgkin and Hodgkin lymphoma. Mod Pathol, 17, pp. 954-961.
20. McCarthy, H., Wierda, W. G., Barron, L. L., Cromwell, C. C., Wang, J. and Coombes, K. R. (2003) High expression of activation-induced cytidine deaminase (AID) and splice variants is a distinctive feature of poor-prognosis chronic lymphocytic leukemia. Blood, 101, pp. 4903-4908.
21. Chiorazzi, N. and Ferrarini, M. (2006) Evolving view of the in-vivo kinetics of chronic lymphocytic leukemia B cells. Hematology (Am Soc Hematol Educ Program), pp. 273-278.
22. Levesque, M. C., O'Loughlin, C. W. and Weinberg, J. B. (2001) Use of serum-free media to minimize apoptosis of chronic lymphocytic leukemia cells during in vitro culture. Leukemia, 15, pp. 1305-1307.
23. Zent, C. S., Chen, J. B., Kurten, R. C., Kaushal, G. P., Lacy, H Marie and Schichman, S. A. (2004) Alemtuzumab (CAMPATH 1H) does not kill chronic lymphocytic leukemia cells in serum free medium. Leuk Res, 28, pp. 495-507.
24. Liu, B. C., Zhang, L., Lv, L. L., Wang, Y. L., Liu, D. G. and Zhang, X. L. (2006) Application of antibody array technology in the analysis of urinary cytokine profiles in patients with chronic kidney disease. Am J Nephrol, 26, pp. 483-490.
25. Jinquan, T., Jacobi, H. H., Jing, C., Millner, A., Sten, E. and Hviid, L. (2003) CCR3 expression induced by IL-2 and IL-4 functioning as a death receptor for B cells. J Immunol, 171, pp. 1722-1731.
26. Kishimoto, T. (1989) The biology of interleukin-6. Blood, 74, pp. 1-10.
27. Van Snick, J. (1990) Interleukin-6: An overview. Annu Rev Immunol, 8, pp. 253-278.
28. Fayad, L., Keating, M. J., Reuben, J. M., O'Brien, S., Lee, B. N., Lerner, S. and Kurzrock, R. (2001) Interleukin-6 and interleukin-10 levels in chronic lymphocytic leukemia: Correlation with phenotypic characteristics and outcome. Blood, 97, pp. 256-263.
29. Biondi, A., Rossi, V., Bassan, R., Barbui, T., Bettoni, S. and Sironi, M. (1989) Constitutive expression of the interleukin-6 gene in chronic lymphocytic leukemia. Blood, 73, pp. 1279-1284.
30. Lahat, N., Aghai, E., Maroun, B., Kinarty, A., Quitt, M. and Froom, P. (1991) Increased spontaneous secretion of IL-6 from B cells of patients with B chronic lymphatic leukaemia (B-CLL) and autoimmunity. Clin Exp Immunol, 85, pp. 302-306.
31. Hulkkonen, J., Vilpo, J., Vilpo, L. and Hurme, M. (1998) Diminished production of interleukin-6 in chronic lymphocytic leukaemia (B-CLL) cells from patients at advanced stages of disease. Tampere CLL Group. Br J Haematol, 100, pp. 478-483.
32. Emilie, D., Leger-Ravet, M. B., Devergne, O., Raphael, M., Peuchmaur, M. and Coumbaras, J. (1993) Intratumoral production of IL-6 in B cell chronic lymphocytic leukemia and B lymphomas. Leuk Lymphoma, 11, pp. 411-417.