Normal patterns of expression of glycosylphosphatidylinositol-anchored proteins on different subsets of peripheral blood cells: A frame of reference for the diagnosis of paroxysmal nocturnal hemoglobinuria

Cytometry Part B - Clinical Cytometry

Volumn 70, Issue 2, 2006, Pages 71-81

  Hernández Campo, Pilar María ^a   Almeida, Julia ^a   Sánchez, María Luz ^a   Malvezzi, Mariester ^b   Orfao, Alberto ^a,c  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^c HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

Author keywords

Flow cytometry; GPI anchored proteins; Immunophenotype; PNH

Indexed keywords

CD4 ANTIGEN; CD48 ANTIGEN; CD52 ANTIGEN; CD56 ANTIGEN; CD59 ANTIGEN; CD8 ANTIGEN; CELL SURFACE PROTEIN; DECAY ACCELERATING FACTOR; GLYCOSYLPHOSPHATIDYLINOSITOL; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; MEMBRANE PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; ANTIGEN EXPRESSION; ARTICLE; BLOOD SAMPLING; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; DENDRITIC CELL; ERYTHROCYTE; FEMALE; FLOW CYTOMETRY; HEMOGLOBINURIA; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; MALE; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PATIENT MONITORING; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; THROMBOCYTE;

ANTIGENS, CD; ANTIGENS, CD55; ANTIGENS, CD58; ANTIGENS, CD59; ANTIGENS, NEOPLASM; BIOLOGICAL MARKERS; BLOOD PLATELETS; FEMALE; FLOW CYTOMETRY; GLYCOPROTEINS; GLYCOSYLPHOSPHATIDYLINOSITOLS; HEMATOPOIETIC STEM CELLS; HEMOGLOBINURIA, PAROXYSMAL; HUMANS; IMMUNOPHENOTYPING; LEUKOCYTES; MALE; MIDDLE AGED; REFERENCE STANDARDS;

EID: 33644898822     PISSN: 15524949     EISSN: None     Source Type: Journal    
DOI: 10.1002/cyto.b.20087     Document Type: Article

References (30)

1. Meletis J, Terpos E. Recent insights into the pathophysiology of paroxysmal hemoglobinuria nocturnal. Med Sci Monit 2003;9:RA161-RA172.
2. Hernández-Campo PM, Martín-Ayuso M, Almeida J, López A, Orfao A. Comparative analysis of different flow cytometry-based immnophenotypic methods for the analysis of CD59 and CD55 expression on major peripheral blood cell subsets. Cytometry 2002;50:191-201.
3. Tomita M. Biochemical background of paroxysmal nocturnal hemoglobinuria. Biochim Biophys Acta 1999;1455:269-286.
4. Takeda J, Miyata T, Kawagoe K, Iida Y, Endo Y, Fujita T, Takahashi M, Kitani T, Kinoshita T. Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell 1993;73:703-711.
5. Rosse WF. New insights into paroxysmal nocturnal hemoglobinuria. Curr Opin Haematol 2001;8:61-67.
6. Van der Schoot CE, Huizinga TWJ, van't Veer-Korthof ET, Wijmans R, Pinkster J, von dem Borne AEG. Deficiency of glycosyl-phosphatidylinositol- linked membrane glycoproteins of leukocytes in paroxysmal nocturnal hemoglobinuria: description of a new diagnostic cytofluorometric assay. Blood 1990;76:1853-1859.
7. Hall SE, Rosse WF. The use of monoclonal antibodies and flow cytometry in the diagnosis of paroxysmal nocturnal hemoglobinuria. Blood 1996;87:5332-5340.
8. Richards SJ, Hillmen P. Advances in the laboratory diagnosis of paroxysmal nocturnal hemoglobinuria. Clin Appl Immunol Rev I 2001;1:315-330.
9. Cui W, Fan Y, Yang M, Zhang Z. Expression of CD59 on lymphocyte and the subsets and its potential clinical application for the paroxysmal nocturnal hemoglobinuria diagnosis. Clin Lab Haematol 2004;26:95-100.
10. Boccuni P, Del Vecchio L, Di Noto R, Rotoli B. Glycosyl phosphatidylinositol (GPI)-anchored molecules and the pathogenesis of paroxysmal nocturnal hemoglobinuria. Crit Rev Oncol/Hematol 2000;33:25-43.
11. Hibbs ML, Selvaraj P, Carpen O, Springer TA, Kuster H, Jouvin MH, Kinet JP. Mechanism for regulating expression of membrane isoforms of FcγRIII (CD16). Science 1989;246:1608-1611.
12. Ariel O, Kukulansky T, Raz N, Hollander N. Distinct membrane localization and kinase association of the two isoforms of CD58. Cell Sign 2004;16:667-673.
13. Jaikaran E. et al. J Thromb Haemost 2003;1:198 (abstract).
14. Alfinito F, Del Vecchio L, Rocco S, Boccuni P, Musto P, Rotoli B. Blood cell flow cytometry in paroxysmal nocturnal hemoglobinuria: a tool for measuring the extent of the PNH clone. Leukemia 1996;10:1326-1330.
15. Piedras J, López-Karpovitch X. Flow cytometric analysis of glycosylphosphatidylinositol-anchored proteins to assess paroxysmal nocturnal hemoglobinuria clone size. Cytometry 2000;42:234-238.
16. Sánchez ML, Almeida J, Vidriales B, López-Berges MC, García-Marcos MA, Moro MJ, Corrales A, Calmuntia MJ, San Miguel JF, Orfao A. Incidence of phenotypic aberrations in a series of 467 patients with B-chronic lymphoproliferative disorders: basis for the design of specific 4-color stainings to be used for minimal residual disease investigation. Leukemia 2002;16:1460-1469.
17. Iyer SB, Bishop JE, Abrams B, Maino VC, Ward AJ, Christian TP, Davis KA. QuantiBRITE: a new standard for fluorescence quantitation (White Paper). San Jose, CA:Becton Dickinson Immunocytometry Systems; 1997.
18. Lenkei R, Andersson B. Determination of the antibody binding capacity of lymphocyte membrane antigens by flow cytometry in 58 blood donors. J Immunol Methods 1995;183:267-277.
19. 2- macroglobulin/C3,C4,C5 family of thioester-containing proteins. Blood 2002;99:1683-1691.
20. Ortolan E, Vacca P Capobianco A, Armando E, Crivellin F, Horenstein A, Malavasi F. CD157, the Janus of CD38 but with a unique personality. Cell Biochem Funct 2002;20:309-322.
21. Richards SJ, Rawstron AC, Hillmen P. Application of flow cytometry to the diagnosis of paroxysmal nocturnal hemoglobinuria. Cytometry 2000;42:223-233.
22. Kaplan D. Enzymatic amplification staining for cell surface antigens. Current Protocols in Cytometry. 2003.6.14.1-6.14.10.
23. Taylor VC, Sims M, Brett S, Field MC. Antibody section against CD52 produces a paroxysmal nocturnal hemoglobinuria phenotype in human lymphocytes by a novel mechanism. Biochem J 1997;322:919-925.
24. Richards SJ, Morgan GJ, Hillmen P. Analysis of T cells in paroxysmal nocturnal hemoglobinuria provides direct evidence that thymic T-cell production declines with age. Blood 1999;94:2790-2799.
25. Richards SJ, Norfolk DR, Swirsky DM, Hillmen P. Lymphocyte subset analysis and glycosilphosphatidylinositol phenotype in patients with paroxysmal nocturnal hemoglobinuria. Blood 1998;92:1799-1806.
26. PMN (CD16) in paroxysmal nocturnal hemoglobinuria. J Clin Invest 1991;87:58-67.
27. Lavabre-Bertrand T, Duperray C, Brunet C, Poncelet P, Exbrayat C, Bourquard P, Lavabre-Bertrand C, Brochier J, Navarro M, Janossy G. Quantification of CD24 and CD45 antigens in parallel allows a precise determination of B-cell maturation stages: relevance for the study of B-cell neoplasias. Leukemia 1994;8:402-408.
28. Elghetany MT, Patel J. Assessment of CD24 expression on bone marrow neutrophilic granulocytes: CD24 is a marker for the myelocytic stage of development. Am J Hematol 2002;71:348-349.
29. Béné MC, Castoldi G, Knapp W, Rigolin GM, Escribano L, Lemez P, Ludwing W-D, Matutes E, Orfao A, Lanza F, Van't Veer M. CD87 (urokinase-type plasminogen activator receptor), function and pathology in haematological disorders: a review. Leukemia 2004;18:394-400.
30. Tarui T, Mazart AP, Cines DB, Takada Y. Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction. J Biol Chem 2001;276:3983-3990.