Enhanced magnitude and breadth of neutralizing humoral response to a DNA vaccine targeting the DHBV envelope protein delivered by in vivo electroporation

Virology

Volumn 425, Issue 1, 2012, Pages 61-69

  Khawaja, Ghada ^a,b   Buronfosse, Thierry ^b,c   Jamard, Catherine ^b   Guerret, Sylviane ^d   Zoulim, Fabien ^a,b   Luxembourg, Alain ^e   Hannaman, Drew ^e   Evans, Claire ^e   Hartmann, Daniel ^a   Cova, Lucyna ^a,b  

^a UNIVERSITÉ LYON 1   (France)

^b CENTRE DE RECHERCHE EN CANCÉROLOGIE DE LYON   (France)

^c VETAGRO SUP   (France)

^d Novotec   (France)

^e Ichor Medical Systems Inc   (United States)

Author keywords

B cell epitopes; DNA vaccine; Duck HBV (DHBV); Electroporation; Hepatitis B virus (HBV); Neutralization

Indexed keywords

DNA VACCINE; EPITOPE; PROTEIN PRES; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; B LYMPHOCYTE; CELL SPECIFICITY; CONTROLLED STUDY; DRUG TARGETING; DUCK HEPATITIS B VIRUS; ELECTROPORATION; HUMORAL IMMUNITY; IN VIVO GENE TRANSFER; LOW DRUG DOSE; NEEDLE; NONHUMAN; PRIORITY JOURNAL; VIRUS NEUTRALIZATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, NEUTRALIZING; DRUG DELIVERY SYSTEMS; DUCKS; ELECTROPORATION; EPITOPES, B-LYMPHOCYTE; HEPADNAVIRIDAE INFECTIONS; HEPATITIS B ANTIBODIES; HEPATITIS B VIRUS, DUCK; HEPATITIS, VIRAL, ANIMAL; HUMANS; MOLECULAR SEQUENCE DATA; NEUTRALIZATION TESTS; PROTEIN PRECURSORS; VACCINES, DNA; VIRAL ENVELOPE PROTEINS;

DUCK HEPATITIS B VIRUS; HEPATITIS B VIRUS;

EID: 84856563428     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2012.01.001     Document Type: Article

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