Electroporation enhances immunogenicity of a DNA vaccine expressing woodchuck hepatitis virus surface antigen in woodchucks

Journal of Virology

Volumn 85, Issue 10, 2011, Pages 4853-4862

  Liu, Katherine H ^a   Ascenzi, Mary A ^a   Bellezza, Christine A ^a   Bezuidenhout, Abraham J ^a   Cote, Paul J ^b   Gonzalez Aseguinolaza, Gloria ^c   Hannaman, Drew ^d   Luxembourg, Alain ^d   Evans, Claire F ^d   Tennant, Bud C ^a   Menne, Stephan ^a  

^a Department of Obstetrics Gynecology   (United States)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF NAVARRA   (Spain)

^d Ichor Medical Systems Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; HEPATITIS ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 4; PLACEBO; PLASMID DNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WOODCHUCK HEPATITIS VIRUS SURFACE ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DNA IMMUNIZATION; DRUG DELIVERY SYSTEM; DRUG DOSE COMPARISON; DRUG MEGADOSE; ELECTROPORATION; FEMALE; GENE EXPRESSION; IMMUNOGENICITY; LOW DRUG DOSE; LYMPHOCYTE PROLIFERATION; MALE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH2 CELL; WOODCHUCK; WOODCHUCK HEPATITIS VIRUS;

ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, SURFACE; ELECTROPORATION; FEMALE; HEPATITIS B VACCINES; HEPATITIS B VIRUS, WOODCHUCK; MARMOTA; PLASMIDS; T-LYMPHOCYTES; TH1 CELLS; VACCINATION; VACCINES, DNA; VIRAL PROTEINS;

ANIMALIA; HEPATITIS B VIRUS; MARMOTA MONAX; WOODCHUCK HEPATITIS VIRUS;

EID: 79955426288     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02437-10     Document Type: Article

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