Identification of Antigenic Regions of Duck Hepatitis B Virus Core Protein with Antibodies Elicited by DNA Immunization and Chronic Infection

Journal of Virology

Volumn 78, Issue 4, 2004, Pages 1945-1953

  Thermet, A ^a   Robaczewska, M ^a   Rollier, C ^a   Hantz, O ^a   Trepo, C ^a   Deleage, G ^b   Cova, L ^a  

^a INSERM   (France)

^b INSTITUT DE BIOLOGIE ET CHIMIE DES PROTÉINES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CORE PROTEIN; DNA; EPITOPE; NAKED DNA; PROTEIN ANTIBODY; VIRUS ENVELOPE PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DETECTION; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ANTIGEN STRUCTURE; ANTIGENICITY; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE INSERTION; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMORAL IMMUNITY; IMMUNIZATION; IMMUNOREACTIVITY; MOLECULAR MODEL; NONHUMAN; PEPTIDE ANALYSIS; PLASMID; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; STRUCTURE ANALYSIS; VIRUS CORE;

ANIMALS; EPITOPES; HEPATITIS B; HEPATITIS B ANTIBODIES; HEPATITIS B CORE ANTIGENS; HEPATITIS B VACCINES; HEPATITIS B VIRUS, DUCK; HEPATITIS B, CHRONIC; HUMANS; IMMUNIZATION; MODELS, MOLECULAR; PLASMIDS; VACCINES, DNA;

EID: 0842282832     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.4.1945-1953.2004     Document Type: Article

References (36)

1. Borel, C., C. Sunyach, O. Hantz, C. Trepo, and A. Kay. 1998. Phosphorylation of DHBV pre-S: identification of the major site of phosphorylation and effects of mutations on the virus life cycle. Virology 242:90-98.
2. Bringas, R. 1997. Folding and assembly of hepatitis B virus core protein: a new model proposal. J. Struct. Biol. 118:189-196.
3. Chassot, S., V. Lambert, A. Kay, C. Godinot, B. Roux, C. Trepo, and L. Cova. 1993. Fine mapping of neutralization epitopes on duck hepatitis B virus (DHBV) pre-S protein using monoclonal antibodies and overlapping peptides. Virology 192:217-223.
4. Chassot, S., V. Lambert, A. Kay, C. Godinot, C. Trepo, and L. Cova. 1994. Identification of major antigenic domains of duck hepatitis B virus pre-S protein by peptide scanning. Virology 200:72-78.
5. Combet, C., M. Jambon, G. Deleage, and C. Geourjon. 2002. Geno3D: automatic comparative molecular modeling of protein. Bioinformatics 18: 213-214.
6. Geourjon, C., and G. Deleage. 1995. ANTHEPROT 2.0: a three-dimensional module fully coupled with protein sequence analysis methods. J. Mol. Graph. 13:199-212.
7. Geysen, H. M., R. H. Meloen, and S. J. Barteling. 1984. Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid. Proc. Natl. Acad. Sci. USA 81:3998-4002.
8. Geysen, H. M., S. J. Rodda, T. J. Mason, G. Tribbick, and P. G. Schoofs. 1987. Strategies for epitope analysis using peptide synthesis. J. Immunol. Methods 102:259-274.
9. Hinkula, J., C. Svanholm, S. Schwartz, P. Lundholm, M. Brytting, G. Engstrom, R. Benthin, H. Glaser, G. Sutter, B. Kohleisen, V. Erfle, K. Okuda, H. Wigzell, and B. Wahren. 1997. Recognition of prominent viral epitopes induced by immunization with human immunodeficiency virus type 1 regulatory genes. J. Virol. 71:5528-5539.
10. Jilbert, A. R., and I. Kotlarski. 2000. Immune responses to duck hepatitis B virus infection. Dev. Comp. Immunol. 24:285-302.
11. Kenney, J. M., C. H. von Bonsdorff, M. Nassal, and S. D. Fuller. 1995. Evolutionary conservation in the hepatitis B virus core structure: comparison of human and duck cores. Structure 3:1009-1019.
12. b mice. J. Immunol. 156:3687-3695.
13. Lai, W. C., and M. Bennett. 1998. DNA vaccines. Crit. Rev. Immunol. 18:449-484.
14. Lambert, V., S. Chassot, A. Kay, C. Trépo, and L. Cova. 1991. In vivo neutralization of duck hepatitis B virus by antibodies specific to the N-terminal portion of pre-S protein. Virology 185:446-450.
15. Le Guerhier, F., A. Thermet, S. Guerret, M. Chevallier, C. Jamard, C. S. Gibbs, C. Trepo, L. Cova, and F. Zoulim. 2003. Antiviral effect of adefovir in combination with a DNA vaccine in the duck hepatitis B virus infection model. J. Hepatol. 38:328-334.
16. Lu, M., G. Hilken, J. Kruppenbacher, T. Kemper, R. Schirmbeck, J. Reimann, and M. Roggendorf. 1999. Immunization of woodchucks with plasmids expressing woodchuck hepatitis virus (WHV) core antigen and surface antigen suppresses WHV infection. J. Virol. 73:281-289.
17. Mancini, M., M. Hadchouel, H. L. Davis, R. G. Whalen, P. Tiollais, and M. L. Michel. 1996. DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state. Proc. Natl. Acad. Sci. USA 93:12496-12501.
18. Mandart, E., A. Kay, and F. Galibert. 1984. Nucleotide sequence of a cloned duck hepatitis B virus genome: comparison with woodchuck and human hepatitis B virus sequences. J. Virol. 49:782-792.
19. Michel, M. L., and D. Loirat. 2001. DNA vaccines for prophylactic or therapeutic immunization against hepatitis B. Intervirology 44:78-87.
20. Pugh, J., A. Zweidler, and J. Summers. 1989. Characterization of the major duck hepatitis B virus core particle protein. J. Virol. 63:1371-1376.
21. Rollier, C., C. Charollois, C. Jamard, C. Trepo, and L. Cova. 2000. Maternally transferred antibodies from DNA-immunized avians protect offspring against hepadnavirus infection. J. Virol. 74:4908-4911.
22. Rollier, C., C. Sunyach, L. Barraud, N. Madani, C. Jamard, C. Trepo, and L. Cova. 1999. Protective and therapeutic effect of DNA-based immunization against hepadnavirus large envelope protein. Gastroenterology 116:658-665.
23. Sallberg, M., U. Ruden, L. O. Magnius, H. P. Harthus, M. Noah, and B. Wahren. 1991. Characterisation of a linear binding site for a monoclonal antibody to hepatitis B core antigen. J. Med. Virol. 33:248-252.
24. Sallberg, M., U. Ruden, B. Wahren, and L. O. Magnius. 1994. Immune recognition of linear antigenic regions within the hepatitis B pre-C and C-gene translation products using synthetic peptides. J. Med. Virol. 42:7-15.
25. Schirmbeck, R., X. Zheng, M. Roggendorf, M. Geissler, F. V. Chisari, J. Reimann, and M. Lu. 2001. Targeting murine immune responses to selected T cell- or antibody-defined determinants of the hepatitis B surface antigen by plasmid DNA vaccines encoding chimeric antigen. J. Immunol. 166:1405-1413.
26. Siegel, F., M. Lu, and M. Roggendorf. 2001. Coadministration of gamma interferon with DNA vaccine expressing woodchuck hepatitis virus (WHV) core antigen enhances the specific immune response and protects against WHV infection. J. Virol. 75:5036-5042.
27. Srivastava, I. K., and M. A. Liu. 2003. Gene vaccines. Ann. Intern. Med. 138:550-559.
28. Sunyach, C., C. Rollier, M. Robaczewska, C. Borel, L. Barraud, A. Kay, C. Trepo, H. Will, and L. Cova. 1999. Residues critical for duck hepatitis B virus neutralization are involved in host cell interaction. J. Virol. 73:2569-2575.
29. Tahtinen, M., A. Ranki, S. L. Valle, V. Ovod, and K. Krohn. 1997. B-cell epitopes in HIV-1 Tat and Rev proteins colocalize with T-cell epitopes and with functional domains. Biomed. Pharmacother. 51:480-487.
30. Thermet, A., C. Rollier, F. Zoulim, C. Trepo, and L. Cova. 2003. Progress in DNA vaccine for prophylaxis and therapy of hepatitis B. Vaccine 21:659-662.
31. Triyatni, M., A. R. Jilbert, M. Qiao, D. S. Miller, and C. J. Burrell. 1998. Protective efficacy of DNA vaccines against duck hepatitis B virus infection. J. Virol. 72:84-94.
32. Wang, L., J. G. Menting, C. G. Black, A. Stowers, D. C. Kaslow, S. L. Hoffman, and R. L. Coppel. 2000. Differences in epitope recognition, isotype and titer of antisera to Plasmodium falciparum merozoite surface protein 4 raised by different modes of DNA or protein immunization. Vaccine 19:816-824.
33. Wynne, S. A., R. A. Crowther, and A. G. Leslie. 1999. The crystal structure of the human hepatitis B virus capsid. Mol. Cell 3:771-780.
34. Yang, W., J. Guo, Z. Ying, S. Hua, W. Dong, and H. Chen. 1994. Capsid assembly and involved function analysis of twelve core protein mutants of duck hepatitis B virus. J. Virol. 68:338-345.
35. Yuasa, S., R. C. Cheung, Q. Pham, W. S. Robinson, and P. L. Marion. 1991. Peptide mapping of neutralizing and nonneutralizing epitopes of duck hepatitis B virus pre-S polypeptide. Virology 181:14-21.
36. Zheng, J., F. Schodel, and D. L. Peterson. 1992. The structure of hepadnaviral core antigens. Identification of free thiols and determination of the disulfide bonding pattern. J. Biol. Chem. 267:9422-9429.