Increased gene expression and inflammatory cell infiltration caused by electroporation are both important for improving the efficacy of DNA vaccines

Journal of Biotechnology

Volumn 110, Issue 1, 2004, Pages 1-10

  Babiuk, Shawn ^a   Baca Estrada, Maria E ^b   Foldvari, Marianna ^a   Middleton, Dorothy M ^c   Rabussay, Deitmar ^d   Widera, Georg ^d   Babiuk, Lorne A ^b  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

^d Inovio Biomedical Corporation   (United States)

Author keywords

DNA vaccine; Electroporation; Gene expression; Inflammation; Pigs

Indexed keywords

BIODIVERSITY; DNA; GENES; IMMUNOLOGY; VACCINES;

ELECTROPORATION; INFLAMMATORY CELLS;

BIOTECHNOLOGY;

DNA VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; ELECTROPORATION; FEMALE; GENE EXPRESSION; IMMUNE RESPONSE; INFLAMMATION; MALE; NONHUMAN; PLASMID; PRIORITY JOURNAL; SWINE;

ANIMALS; ELECTROPORATION; FEMALE; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; HEPATITIS B SURFACE ANTIGENS; INFLAMMATION; INJECTIONS, INTRAMUSCULAR; INTERFERON TYPE II; LEUKOCYTES; LUCIFERASES; MALE; MUSCLE, SKELETAL; NECROSIS; PLASMIDS; SWINE; TIME FACTORS; UP-REGULATION; VACCINES, DNA; VIRAL ENVELOPE PROTEINS;

EID: 1942455782     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2004.01.015     Document Type: Article

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