메뉴 건너뛰기




Volumn 33, Issue SUPPL. 77, 2006, Pages 3-11

Crossroads of B cell activation in autoimmunity: Rationale of targeting B cells

Author keywords

Autoantibodies; B cells; Pathogenesis; Rheumatoid arthritis

Indexed keywords

ABATACEPT; AUTOANTIBODY; BELIMUMAB; BIOLOGICAL PRODUCT; CD20 ANTIBODY; CD20 ANTIGEN; CD22 ANTIGEN; CYTOKINE; DISEASE MODIFYING ANTIRHEUMATIC DRUG; EPRATUZUMAB; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN LAMBDA CHAIN; INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; METHOTREXATE; MONOCLONAL ANTIBODY; RITUXIMAB; TUMOR NECROSIS FACTOR ANTIBODY; MEMBRANE ANTIGEN;

EID: 84856488806     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (87)

References (56)
  • 1
    • 0028966993 scopus 로고
    • The pathogenesis of rheumatoid arthritis and the development of therapeutic strategies for the clinical investigation of biologics
    • Panayi GS. The pathogenesis of rheumatoid arthritis and the development of therapeutic strategies for the clinical investigation of biologics. Agents Actions Suppl 1995;47:1-21.
    • (1995) Agents Actions Suppl , vol.47 , pp. 1-21
    • Panayi, G.S.1
  • 2
    • 2442433618 scopus 로고    scopus 로고
    • Pathogenic roles of B cells in human autoimmunity; insights from the clinic
    • Martin F, Chan AC. Pathogenic roles of B cells in human autoimmunity; insights from the clinic. Immunity 2004;20:517-27.
    • (2004) Immunity , vol.20 , pp. 517-527
    • Martin, F.1    Chan, A.C.2
  • 3
    • 84959744414 scopus 로고
    • Advances in immunotherapy of rheumatoid arthritis: Clinical and immunological findings following treatment with anti-CD4 antibodies
    • Horneff G, Emmrich F, Burmester GR. Advances in immunotherapy of rheumatoid arthritis: clinical and immunological findings following treatment with anti-CD4 antibodies. Br J Rheumatol 1993;32 Suppl 4:39-47.
    • (1993) Br J Rheumatol , vol.32 , Issue.SUPPL. 4 , pp. 39-47
    • Horneff, G.1    Emmrich, F.2    Burmester, G.R.3
  • 4
    • 0035555161 scopus 로고    scopus 로고
    • Systemic lupus erythematosus: An autoimmune disease of B cell hyperactivity
    • Lipsky PE. Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity. Nat Immunol 2001;2:764-6.
    • (2001) Nat Immunol , vol.2 , pp. 764-766
    • Lipsky, P.E.1
  • 8
    • 0042470566 scopus 로고    scopus 로고
    • Regulatory mechanisms that determine the development and function of plasma cells
    • Calame KL, Lin KI, Tunyaplin C. Regulatory mechanisms that determine the development and function of plasma cells. Annu Rev Immunol 2003;21:205-30.
    • (2003) Annu Rev Immunol , vol.21 , pp. 205-230
    • Calame, K.L.1    Lin, K.I.2    Tunyaplin, C.3
  • 10
    • 27744444832 scopus 로고    scopus 로고
    • RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement
    • Lau CM, Broughton C, Tabor AS, et al. RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. J Exp Med 2005;202:1171-7.
    • (2005) J Exp Med , vol.202 , pp. 1171-1177
    • Lau, C.M.1    Broughton, C.2    Tabor, A.S.3
  • 11
    • 2942635727 scopus 로고    scopus 로고
    • Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice
    • Hoyer BF, Moser K, Hauser AE, et al. Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice. J Exp Med 2004;199:1577-84.
    • (2004) J Exp Med , vol.199 , pp. 1577-1584
    • Hoyer, B.F.1    Moser, K.2    Hauser, A.E.3
  • 12
    • 2942692040 scopus 로고    scopus 로고
    • Targeting plasma cells in autoimmune diseases
    • Tarlinton DM, Hodgkin PD. Targeting plasma cells in autoimmune diseases. J Exp Med 2004;199:1451-4.
    • (2004) J Exp Med , vol.199 , pp. 1451-1454
    • Tarlinton, D.M.1    Hodgkin, P.D.2
  • 14
    • 0035879123 scopus 로고    scopus 로고
    • Lymphoid neogenesis in rheumatoid synovitis
    • Takemura S, Braun A, Crowson C, et al. Lymphoid neogenesis in rheumatoid synovitis. J Immunol 2001;167:1072-80.
    • (2001) J Immunol , vol.167 , pp. 1072-1080
    • Takemura, S.1    Braun, A.2    Crowson, C.3
  • 15
    • 0030070295 scopus 로고    scopus 로고
    • Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis
    • Schroder AE, Greiner A, Seyfert C, Berek C. Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis. Proc Natl Acad Sci USA 1996;93:221-5.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 221-225
    • Schroder, A.E.1    Greiner, A.2    Seyfert, C.3    Berek, C.4
  • 16
    • 0031974911 scopus 로고    scopus 로고
    • Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies
    • Schellekens GA, de Jong BA, van den Hoogen FH, van de Putte LB, van Venrooij WJ. Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies. J Clin Invest 1998;101:273-81.
    • (1998) J Clin Invest , vol.101 , pp. 273-281
    • Schellekens, G.A.1    De Jong, B.A.2    Van Den Hoogen, F.H.3    Van De Putte, L.B.4    Van Venrooij, W.J.5
  • 17
    • 0035001202 scopus 로고    scopus 로고
    • Diagnostic accuracy of the anti-citrulline antibody assay for rheumatoid arthritis
    • Bizzaro N, Mazzanti G, Tonutti E, Villalta D, Tozzoli R. Diagnostic accuracy of the anti-citrulline antibody assay for rheumatoid arthritis. Clin Chem 2001;47:1089-93.
    • (2001) Clin Chem , vol.47 , pp. 1089-1093
    • Bizzaro, N.1    Mazzanti, G.2    Tonutti, E.3    Villalta, D.4    Tozzoli, R.5
  • 18
    • 8544247220 scopus 로고    scopus 로고
    • Autoantibodies in normals - The value of predicting rheumatoid arthritis
    • Dorner T, Hansen A. Autoantibodies in normals - the value of predicting rheumatoid arthritis. Arthritis Res Ther 2004;6:282-84.
    • (2004) Arthritis Res Ther , vol.6 , pp. 282-284
    • Dorner, T.1    Hansen, A.2
  • 19
    • 0037732689 scopus 로고    scopus 로고
    • The role of B cells in rheumatoid arthritis: Mechanisms and therapeutic targets
    • Dorner T, Burmester GR. The role of B cells in rheumatoid arthritis: mechanisms and therapeutic targets. Curr Opin Rheumatol 2003;15:246-52.
    • (2003) Curr Opin Rheumatol , vol.15 , pp. 246-252
    • Dorner, T.1    Burmester, G.R.2
  • 20
    • 0033033201 scopus 로고    scopus 로고
    • Do self-perpetuating B lymphocytes drive human autoimmune disease?
    • Edwards JC, Cambridge G, Abrahams VM. Do self-perpetuating B lymphocytes drive human autoimmune disease? Immunology 1999;97:188-96.
    • (1999) Immunology , vol.97 , pp. 188-196
    • Edwards, J.C.1    Cambridge, G.2    Abrahams, V.M.3
  • 21
    • 0035050214 scopus 로고    scopus 로고
    • Role of B cells in the pathogenesis of rheumatoid arthritis: Potential implications for treatment
    • Gause A, Berek C. Role of B cells in the pathogenesis of rheumatoid arthritis: potential implications for treatment. BioDrugs 2001;15:73-9.
    • (2001) BioDrugs , vol.15 , pp. 73-79
    • Gause, A.1    Berek, C.2
  • 22
    • 0142218537 scopus 로고    scopus 로고
    • B cell therapy for rheumatoid arthritis: The rituximab (anti-CD20) experience
    • Shaw T, Quan J, Totoritis MC. B cell therapy for rheumatoid arthritis: the rituximab (anti-CD20) experience. Ann Rheum Dis 2003;62 Suppl 2:ii55-ii59.
    • (2003) Ann Rheum Dis , vol.62 , Issue.SUPPL. 2
    • Shaw, T.1    Quan, J.2    Totoritis, M.C.3
  • 23
    • 0035167632 scopus 로고    scopus 로고
    • Cutting edge: A role for B lymphocyte stimulator in systemic lupus erythematosus
    • Zhang Z, Roschke V, Baker KP, et al. Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosus. J Immunol 2001;166:6-10
    • (2001) J Immunol , vol.166 , pp. 6-10
    • Zhang, Z.1    Roschke, V.2    Baker, K.P.3
  • 24
    • 13444252282 scopus 로고    scopus 로고
    • Remission of proliferative lupus nephritis following B cell depletion therapy is preceded by down-regulation of the T cell costimulatory molecule CD40 ligand: An open-label trial
    • Sfikakis PP, Boletis JN, Lionaki S, et al. Remission of proliferative lupus nephritis following B cell depletion therapy is preceded by down-regulation of the T cell costimulatory molecule CD40 ligand: an open-label trial. Arthritis Rheum 2005;52:501-13.
    • (2005) Arthritis Rheum , vol.52 , pp. 501-513
    • Sfikakis, P.P.1    Boletis, J.N.2    Lionaki, S.3
  • 25
    • 14044251596 scopus 로고    scopus 로고
    • Down-regulation of CD40 and CD80 on B cells in patients with life-threatening systemic lupus erythematosus after successful treatment with rituximab
    • Tokunaga M, Fujii K, Saito K, et al. Down-regulation of CD40 and CD80 on B cells in patients with life-threatening systemic lupus erythematosus after successful treatment with rituximab. Rheumatology Oxford 2005;44:176-82.
    • (2005) Rheumatology Oxford , vol.44 , pp. 176-182
    • Tokunaga, M.1    Fujii, K.2    Saito, K.3
  • 26
    • 0035677577 scopus 로고    scopus 로고
    • Immunoglobulin variable-region gene usage in systemic autoimmune diseases
    • Dorner T, Lipsky PE. Immunoglobulin variable-region gene usage in systemic autoimmune diseases. Arthritis Rheum 2001;44:2715-27.
    • (2001) Arthritis Rheum , vol.44 , pp. 2715-2727
    • Dorner, T.1    Lipsky, P.E.2
  • 27
    • 0034469424 scopus 로고    scopus 로고
    • B cells in rheumatoid arthritis
    • Kim HJ, Berek C. B cells in rheumatoid arthritis. Arthritis Res 2000;2:126-31.
    • (2000) Arthritis Res , vol.2 , pp. 126-131
    • Kim, H.J.1    Berek, C.2
  • 28
    • 0027533185 scopus 로고
    • Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM
    • Korthauer U, Graf D, Mages HW, et al. Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM. Nature 1993;361:539-41.
    • (1993) Nature , vol.361 , pp. 539-541
    • Korthauer, U.1    Graf, D.2    Mages, H.W.3
  • 29
    • 0036446020 scopus 로고    scopus 로고
    • Morphological and molecular pathology of the B cell response in synovitis of rheumatoid arthritis
    • Magalhaes R, Stiehl P, Morawietz L, Berek C, Krenn V. Morphological and molecular pathology of the B cell response in synovitis of rheumatoid arthritis. Virchows Arch 2002;441:415-27.
    • (2002) Virchows Arch , vol.441 , pp. 415-427
    • Magalhaes, R.1    Stiehl, P.2    Morawietz, L.3    Berek, C.4    Krenn, V.5
  • 30
    • 5644273872 scopus 로고    scopus 로고
    • Involvement of inducible costimulator in the exaggerated memory B cell and plasma cell generation in systemic lupus erythematosus
    • Hutloff A, Buchner K, Reiter K, et al. Involvement of inducible costimulator in the exaggerated memory B cell and plasma cell generation in systemic lupus erythematosus. Arthritis Rheum 2004;50:3211-20.
    • (2004) Arthritis Rheum , vol.50 , pp. 3211-3220
    • Hutloff, A.1    Buchner, K.2    Reiter, K.3
  • 31
    • 0032169223 scopus 로고    scopus 로고
    • Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjogren's syndrome
    • Stott DI, Hiepe F, Hummel M, Steinhauser G, Berek C. Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjogren's syndrome. J Clin Invest 1998;102:938-46.
    • (1998) J Clin Invest , vol.102 , pp. 938-946
    • Stott, D.I.1    Hiepe, F.2    Hummel, M.3    Steinhauser, G.4    Berek, C.5
  • 32
    • 0036676086 scopus 로고    scopus 로고
    • Diminished peripheral blood memory B cells and accumulation of memory B cells in the salivary glands of patients with Sjogren's syndrome
    • Hansen A, Odendahl M, Reiter K, et al. Diminished peripheral blood memory B cells and accumulation of memory B cells in the salivary glands of patients with Sjogren's syndrome. Arthritis Rheum 2002;46:2160-71.
    • (2002) Arthritis Rheum , vol.46 , pp. 2160-2171
    • Hansen, A.1    Odendahl, M.2    Reiter, K.3
  • 33
    • 2442708947 scopus 로고    scopus 로고
    • Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis
    • Serafini B, Rosicarelli B, Magliozzi R, Stigliano E, Aloisi F. Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis. Brain Pathol 2004;14:164-74.
    • (2004) Brain Pathol , vol.14 , pp. 164-174
    • Serafini, B.1    Rosicarelli, B.2    Magliozzi, R.3    Stigliano, E.4    Aloisi, F.5
  • 34
    • 23044443492 scopus 로고    scopus 로고
    • Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans
    • Salzer U, Chapel HM, Webster AD, et al. Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans. Nat Genet 2005;37:820-8.
    • (2005) Nat Genet , vol.37 , pp. 820-828
    • Salzer, U.1    Chapel, H.M.2    Webster, A.D.3
  • 35
    • 23044463627 scopus 로고    scopus 로고
    • TACI is mutant in common variable immunodeficiency and IgA deficiency
    • Castigli E, Wilson SA, Garibyan L, et al. TACI is mutant in common variable immunodeficiency and IgA deficiency. Nat Genet 2005;37:829-34.
    • (2005) Nat Genet , vol.37 , pp. 829-834
    • Castigli, E.1    Wilson, S.A.2    Garibyan, L.3
  • 36
    • 0242495542 scopus 로고    scopus 로고
    • EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switching
    • He B, Raab-Traub N, Casali P, Cerutti A. EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switching. J Immunol 2003;171:5215-24.
    • (2003) J Immunol , vol.171 , pp. 5215-5224
    • He, B.1    Raab-Traub, N.2    Casali, P.3    Cerutti, A.4
  • 37
    • 23044489622 scopus 로고    scopus 로고
    • Unraveling TACIt functions
    • Martin F, Dixit VM. Unraveling TACIt functions. Nat Genet 2005;37:793-4.
    • (2005) Nat Genet , vol.37 , pp. 793-794
    • Martin, F.1    Dixit, V.M.2
  • 38
    • 11844301640 scopus 로고    scopus 로고
    • Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cytokines
    • Ohata J, Zvaifler NJ, Nishio M, et al. Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cytokines. J Immunol 2005;174:864-70.
    • (2005) J Immunol , vol.174 , pp. 864-870
    • Ohata, J.1    Zvaifler, N.J.2    Nishio, M.3
  • 39
    • 0034669990 scopus 로고    scopus 로고
    • Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus
    • Odendahl M, Jacobi A, Hansen A, et al. Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus. J Immunol 2000;165:5970-9.
    • (2000) J Immunol , vol.165 , pp. 5970-5979
    • Odendahl, M.1    Jacobi, A.2    Hansen, A.3
  • 40
    • 0041384263 scopus 로고    scopus 로고
    • Perturbations of peripheral B lymphocyte homoeostasis in children with systemic lupus erythematosus
    • Odendahl M, Keitzer R, Wahn U, et al. Perturbations of peripheral B lymphocyte homoeostasis in children with systemic lupus erythematosus. Ann Rheum Dis 2003;62:851-8.
    • (2003) Ann Rheum Dis , vol.62 , pp. 851-858
    • Odendahl, M.1    Keitzer, R.2    Wahn, U.3
  • 41
    • 0037991063 scopus 로고    scopus 로고
    • Correlation between circulating CD27 high plasma cells and disease activity in patients with systemic lupus erythematosus
    • Jacobi AM, Odendahl M, Reiter K, et al. Correlation between circulating CD27 high plasma cells and disease activity in patients with systemic lupus erythematosus. Arthritis Rheum 2003;48:1332-42.
    • (2003) Arthritis Rheum , vol.48 , pp. 1332-1342
    • Jacobi, A.M.1    Odendahl, M.2    Reiter, K.3
  • 42
    • 20444485767 scopus 로고    scopus 로고
    • Cellular and genetic mechanisms of self tolerance and autoimmunity
    • Goodnow CC, Sprent J, Fazekas de St GB, Vinuesa CG. Cellular and genetic mechanisms of self tolerance and autoimmunity. Nature 2005;435:590-7.
    • (2005) Nature , vol.435 , pp. 590-597
    • Goodnow, C.C.1    Sprent, J.2    Fazekas, D.St.G.B.3    Vinuesa, C.G.4
  • 43
    • 0037565295 scopus 로고    scopus 로고
    • Aberrant activation of B cells in patients with rheumatoid arthritis
    • Lindenau S, Scholze S, Odendahl M, et al. Aberrant activation of B cells in patients with rheumatoid arthritis. Ann NY Acad Sci 2003;987:246-8.
    • (2003) Ann NY Acad Sci , vol.987 , pp. 246-248
    • Lindenau, S.1    Scholze, S.2    Odendahl, M.3
  • 44
    • 33645735407 scopus 로고    scopus 로고
    • Differential expression of chemokine receptors on peripheral blood B cells from patients with rheumatoid arthritis and systemic lupus erythematosus
    • Henneken M, Dorner T, Burmester GR, Berek C. Differential expression of chemokine receptors on peripheral blood B cells from patients with rheumatoid arthritis and systemic lupus erythematosus. Arthritis Res Ther 2005;7:R1001-R1013.
    • (2005) Arthritis Res Ther , vol.7
    • Henneken, M.1    Dorner, T.2    Burmester, G.R.3    Berek, C.4
  • 45
    • 0035881627 scopus 로고    scopus 로고
    • Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus
    • Arce E, Jackson DG, Gill MA, Bennett LB, Banchereau J, Pascual V. Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus. J Immunol 2001;167:2361-9.
    • (2001) J Immunol , vol.167 , pp. 2361-2369
    • Arce, E.1    Jackson, D.G.2    Gill, M.A.3    Bennett, L.B.4    Banchereau, J.5    Pascual, V.6
  • 46
    • 0038516689 scopus 로고    scopus 로고
    • Antibody therapy for rheumatoid arthritis
    • Taylor PC. Antibody therapy for rheumatoid arthritis. Curr Opin Pharmacol 2003;3:323-8.
    • (2003) Curr Opin Pharmacol , vol.3 , pp. 323-328
    • Taylor, P.C.1
  • 47
    • 0036899589 scopus 로고    scopus 로고
    • Treatment of systemic lupus erythematosus by inhibition of T cell costimulation with anti-CD154: A randomized, double-blind, placebo-controlled trial
    • Kalunian KC, Davis JC Jr, Merrill JT, Totoritis MC, Wofsy D. Treatment of systemic lupus erythematosus by inhibition of T cell costimulation with anti-CD154: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2002;46:3251-8.
    • (2002) Arthritis Rheum , vol.46 , pp. 3251-3258
    • Kalunian, K.C.1    Davis Jr., J.C.2    Merrill, J.T.3    Totoritis, M.C.4    Wofsy, D.5
  • 48
    • 0037333857 scopus 로고    scopus 로고
    • A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis
    • Boumpas DT, Furie R, Manzi S, et al. A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis. Arthritis Rheum 2003;48:719-27.
    • (2003) Arthritis Rheum , vol.48 , pp. 719-727
    • Boumpas, D.T.1    Furie, R.2    Manzi, S.3
  • 49
    • 0025980476 scopus 로고
    • Treatment of rheumatoid arthritis with an anti-CD4 monoclonal antibody
    • Horneff G, Burmester GR, Emmrich F, Kalden JR. Treatment of rheumatoid arthritis with an anti-CD4 monoclonal antibody. Arthritis Rheum 1991;34:129-40.
    • (1991) Arthritis Rheum , vol.34 , pp. 129-140
    • Horneff, G.1    Burmester, G.R.2    Emmrich, F.3    Kalden, J.R.4
  • 50
    • 0032697669 scopus 로고    scopus 로고
    • Remission of inflammatory arthropathy in association with anti-CD20 therapy for non-Hodgkin's lymphoma
    • Protheroe A, Edwards JC, Simmons A, Maclennan K, Selby P. Remission of inflammatory arthropathy in association with anti-CD20 therapy for non-Hodgkin's lymphoma. Rheumatology Oxford 1999;38:1150-2.
    • (1999) Rheumatology Oxford , vol.38 , pp. 1150-1152
    • Protheroe, A.1    Edwards, J.C.2    Simmons, A.3    Maclennan, K.4    Selby, P.5
  • 51
    • 0034889699 scopus 로고    scopus 로고
    • Lymphoma in a patient with rheumatoid arthritis receiving methotrexate treatment: Successful treatment with rituximab
    • Stewart M, Malkovska V, Krishnan J, Lessin L, Barth W. Lymphoma in a patient with rheumatoid arthritis receiving methotrexate treatment: successful treatment with rituximab. Ann Rheum Dis 2001;60:892-3.
    • (2001) Ann Rheum Dis , vol.60 , pp. 892-893
    • Stewart, M.1    Malkovska, V.2    Krishnan, J.3    Lessin, L.4    Barth, W.5
  • 52
    • 10744223002 scopus 로고    scopus 로고
    • Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: Double-blind randomised controlled trial
    • Klareskog L, van der Heijde D, de Jager JP, et al. Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial. Lancet 2004;363:675-81.
    • (2004) Lancet , vol.363 , pp. 675-681
    • Klareskog, L.1    Van Der Heijde, D.2    De Jager, J.P.3
  • 53
    • 38149065192 scopus 로고    scopus 로고
    • Updates from B-cell trials: Efficacy
    • Cohen SB. Updates from B-cell trials: Efficacy. J Rheumatol 2006;33 Suppl 77:xx.
    • (2006) J Rheumatol , vol.33 , Issue.SUPPL. 77
    • Cohen, S.B.1
  • 54
    • 33646445418 scopus 로고    scopus 로고
    • B cell regeneration after B cell depletion with rituximab in patients with rheumatoid arthritis: Transient recirculation of plasmablasts and increased levels of germinal center founder cells during the early regeneration phase
    • abstract
    • Roll P, Palanichamy A, Rouziere A, Doerner T, Kneitz C, Tony HP. B cell regeneration after B cell depletion with rituximab in patients with rheumatoid arthritis: transient recirculation of plasmablasts and increased levels of germinal center founder cells during the early regeneration phase. [abstract]. Arthritis Rheum 2005;52 Suppl:S289.
    • (2005) Arthritis Rheum , vol.52 , Issue.SUPPL.
    • Roll, P.1    Palanichamy, A.2    Rouziere, A.3    Doerner, T.4    Kneitz, C.5    Tony, H.P.6
  • 56
    • 14844285020 scopus 로고    scopus 로고
    • Efficacy and safety of rituximab at 2 years following a single treatment in patients with active rheumatoid arthritis
    • abstract
    • Emery P, Sheeran T, Lehane PB, Saiedabadi N, Shaw TM. Efficacy and safety of rituximab at 2 years following a single treatment in patients with active rheumatoid arthritis. [abstract]. Arthritis Rheum 2004;50 Suppl:S659.
    • (2004) Arthritis Rheum , vol.50 , Issue.SUPPL.
    • Emery, P.1    Sheeran, T.2    Lehane, P.B.3    Saiedabadi, N.4    Shaw, T.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.