Opsonization of apoptotic cells by autologous iC3b facilitates clearance by immature dendritic cells, down-regulates DR and CD86, and up-regulates CC chemokine receptor 7

Journal of Experimental Medicine

Volumn 196, Issue 12, 2002, Pages 1553-1561

  Verbovetski, Inna ^a   Bychkov, Hila ^a   Trahtemberg, Uriel ^a   Shapira, Itzhak ^b   Hareuveni, Mara ^b   Ben Tal, Ofira ^b   Kutikov, Ina ^b   Gill, Oranit ^a   Mevorach, Dror ^a,b,c  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Apoptosis; Autoimmunity; Complement; Dendritic cells; Tolerance

Indexed keywords

1,1' DIOCTADECYL 3,3,3',3' TETRAMETHYLINDOCARBOCYANINE; BETA2 INTEGRIN; CD40 LIGAND; CD86 ANTIGEN; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR7; COMPLEMENT COMPONENT C3B; HLA DR ANTIGEN; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

APOPTOSIS; ARTICLE; AUTOIMMUNITY; CELL ACTIVITY; CELL INTERACTION; CELL LABELING; CELL MATURATION; CELL TRANSPORT; COMPLEMENT INHIBITION; DENDRITIC CELL; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; INHIBITION KINETICS; OPSONIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANTIGENS, CD; ANTIGENS, CD86; APOPTOSIS; COMPLEMENT C3B; COMPLEMENT SYSTEM PROTEINS; DENDRITIC CELLS; DOWN-REGULATION; GENES, MHC CLASS II; HLA-DR ANTIGENS; HUMANS; INTEGRIN ALPHAXBETA2; JURKAT CELLS; MACROPHAGE-1 ANTIGEN; MEMBRANE GLYCOPROTEINS; OPSONIN PROTEINS; RECEPTORS, CHEMOKINE; UP-REGULATION;

EID: 0037122009     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20020263     Document Type: Article

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