Interaction of the macrolide azithromycin with phospholipids. I. Inhibition of lysosomal phospholipase A1 activity

European Journal of Pharmacology

Volumn 314, Issue 1-2, 1996, Pages 203-214

  Van Bambeke, Françoise ^a   Montenez, Jean Pierre ^a   Piret, Jocelyne ^a   Tulkens, Paul M ^a   Courtoy, Pierre J ^b   Mingeot Leclercq, Marie Paule ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b International Institute of Cellular and Molecular Pathology   (Belgium)

Author keywords

aminoglycoside; azithromycin; gentamicin; lysosomal phospholipase; macrolide; membrane aggregation; phospholipidosis

Indexed keywords

AMPHOPHILE; AZITHROMYCIN; GENTAMICIN; HEXESTROL BIS(2 DIETHYLAMINOETHYL) ETHER; LIPOSOME; LYSOSOME ENZYME; MACROLIDE; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE A1; PHOSPHOLIPID; POLYCATION; SPERMINE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BINDING; ELECTRICITY; EMBRYO; ENZYME INHIBITION; FIBROBLAST; LIPID VESICLE; LYSOSOME; LYSOSOME STORAGE DISEASE; MEMBRANE FUSION; NONHUMAN; PRIORITY JOURNAL; RAT; ULTRASTRUCTURE;

ANIMALS; ANTI-BACTERIAL AGENTS; AZITHROMYCIN; CELLS, CULTURED; DRUG INTERACTIONS; FIBROBLASTS; GENTAMICINS; LIPOSOMES; PHOSPHOLIPASES A; PHOSPHOLIPIDS; RATS;

EID: 0030600492     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00552-3     Document Type: Article

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