MicroRNAs-based network: A novel therapeutic agent in pituitary adenoma

Medical Hypotheses

Volumn 78, Issue 3, 2012, Pages 380-384

  Shi, Xiuhua ^a   Tao, Bangbao ^b   He, Hua ^b   Sun, Qingfang ^a   Fan, Changyan ^a   Bian, Liuguan ^a   Zhao, Weiguo ^a   Lu, Yi cheng ^b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY RNA; MICRORNA;

APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CELL TRANSFORMATION; GENE EXPRESSION; HUMAN; HYPOPHYSIS; HYPOPHYSIS ADENOMA; METASTASIS; NONHUMAN; PROTEIN EXPRESSION;

CELL TRANSFORMATION, NEOPLASTIC; HUMANS; MICRORNAS; MODELS, BIOLOGICAL; PITUITARY NEOPLASMS; RNA, ANTISENSE;

EID: 84856443617     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2011.12.001     Document Type: Article

References (49)

1. Ezzat S., Asa S.L. Mechanisms of disease: the pathogenesis of pituitary tumors. Nat Clin Pract Endocrinol Metab 2006, 2(4):220-230.
2. Bartel D. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116(2):281-297.
3. Filipowicz W., Jaskiewicz L., Kolb F.A. Post-transcriptional gene silencing by siRNAs and miRNAs. Curr Opin Struct Biol 2005, 15(3):331-341.
4. Sontheimer E.J., Carthew R.W. Silence from within: endogenous siRNAs and miRNAs. Cell 2005, 122(1):9-12.
5. Zhao Y., Deepak Srivastava A developmental view of microRNA functions. Trends Biochem Sci 2007, 32(4):189-197.
6. Ezzat S., Asa S.L., Couldwell W.T., Barr C.E., Dodge W.E., Vance M.L., et al. The prevalence of pituitary adenomas: a systematic review. Cancer 2004, 101(3):613-619.
7. Herman V., Fagin J., Gonsky R., Kovacs K., Melmed S., et al. Clonal origin of pituitary adenomas. J Clin Endocrinol Metab 1990, 71(6):1427-1433.
8. Zhang B., Pan X., et al. MicroRNAs as oncogenes and tumor suppressors. Dev Biol 2007, 302(1):1-12.
9. He L., Thomson J.M., Hemann M.T., et al. A microRNA polycistron as a potential human oncogene. Nature 2005, 435(7043):828-833.
10. Lu J., Getz G., Miska E.A., et al. MicroRNA expression profiles classify human cancers. Nature 2005, 435(7043):834-838.
11. O'Donnell K.A., Wentzel E.A., Zeller K.I., et al. C-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005, 435(7043):839-843.
12. Calin G.A., Sevignani C., Dumitru C.D., et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 2004, 101(9):2999-3004.
13. Hsu S.D., Lin F.M., et al. MiRTarBase: a database curates experimentally validated microRNA-target interactions. Nucleic Acids Res 2010, 1-7.
14. Berezikov E., Guryev V., van de Belt J., et al. Phylogenetic shadowing and computational identification of human microRNA genes. Cell 2005, 120(1):21-24.
15. Lewis B.P., Shih I., Jones-Rhoades M.W., et al. Prediction of mammalian microRNA targets. Cell 2003, 115(7):787-798.
16. Bottoni A., Piccin D., et al. MiR-15a and miR-16-1 down-regulation in pituitary adenomas. J Cell physiol 2005, 204(1):280-285.
17. Bottoni A., Zatelli M.C., et al. Identification of differentially expressed microRNAs by microarray: a possible role for microRNA genes in pituitary adenomas. J Cell physiol 2007, 210(2):370-377.
18. Qian Z.R., Asa S.L., Siomi H., et al. Overexpression of HMGA2 relates to reduction of the let-7 and its relationship to clinicopathological features in pituitary adenomas. Mod Pathol 2009 Mar, 22(3):431-441.
19. Moore L.M., Zhang W. Targeting miR-21 in glioma: a small RNA with big potential. Expert Opin Ther Targets 2010, 14(11):1247-1257.
20. Sayed D., He M., et al. MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of Fas ligand. J Biol Chem 2010, 285(26):20281-20290.
21. Zhu S., Wu H., et al. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 2008, 18(3):350-359.
22. Ohgaki H., Kleihues P. Genetic pathways to primary and secondary glioblastoma. Am J Pathol 2007, 170(5):1445-1453.
23. Gabriely G., Wurdinger T., et al. MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol Cell Biol 2008, 28(17):5280-5369.
24. Thum T., Gross C., et al. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signaling in fibroblasts. Nature 2008, 456(7224):980-984.
25. Amaral F.C., Torres N., Saggioro F. MicroRNAs differentially expressed in ACTH-secreting pituitary tumors. J Clin Endocrinol Metab 2009 Jan, 94(1):320-323.
26. Mao Z.G., He D.S., Zhou J., et al. Differential expression of microRNAs in GH-secreting pituitary adenomas. Diagn Pathol 2010, 5(1):79.
27. Cimmino A., Calin G.A., Fabbri M., et al. MiR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 2005, 102(39):13944-13949.
28. Calin G.A., Dumitru C.D., Shimizu M., et al. Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 2002, 99(24):15524-15529.
29. Michael M.Z., O'Connor S.M., van Holst Pellekaan N.G., et al. Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol Cancer Res 2003, 1(12):882-891.
30. Asa S.L., Ezzat S. The cytogenesis and pathogenesis of pituitary adenomas. Endocr Rev 1998, 19(6):798-827.
31. Zhang Z., Florez S., Gutierrez-Hartmann A., et al. MicroRNAs regulate pituitary development, and microRNA 26b specifically targets lymphoid enhancer factor 1 (Lef-1), which modulates pituitary transcription factor 1 (Pit-1) expression. J Biol Chem 2010, 285(45):34718-34728.
32. Cheng A.M., Byrom W., Shelton J., et al. Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res 2005, 33(4):1290-1297.
33. Barbareschi M., Roldo C., et al. CDX-2 home box gene product expression in neuroendocrine tumors: its role as a marker of intestinal neuroendocrine tumors. Am J Surg Pathol 2004, 28(9):1169-1176.
34. Luttun A., Autiero M., Tjwa M., et al. Genetic dissection of tumor angiogenesis: Are PlGF and VEGFR-1 novel anti-cancer targets?. Biochim Biophys Acta 2004, 1654(1):79-94.
35. Zatelli M.C., Piccin D., Vignali C., et al. Pasireotide, a multiple somatostatin receptor subtype's ligand, reduces cell viability in non-functioning pituitary adenomas by inhibiting vascular endothelial growth factor secretion. Endocr Relat Cancer 2007, 14(1):91-102.
36. Xu Y., Zhang T., Tang H., et al. Overexpression of PIM-1 is a potential biomarker in prostate carcinoma. J Surg Oncol 2005, 92(4):326-330.
37. Laronde-Leblanc N., Wlodawer A. The RIO kinases: An atypical protein kinase family required for ribosome biogenesis and cell cycle progression. Biochim Biophys Acta 2005, 1754(1-2):14-24.
38. Zatelli M.C., degli Uberti E.C. MicroRNAs and possible role in pituitary adenoma. Semin Reprod Med 2008, 26(6):453-460.
39. Olsten M.E., Canton D.A., et al. The Pleckstrin homology domain of CK2 interacting protein-1 is required for interactions and recruitment of protein kinase CK2 to the plasma membrane. J Biol Chem 2004, 279(40):42114-42127.
40. Sorensen J.B. SNARE complexes prepare for membrane fusion. Trends Neuro sci 2005, 28(9):453-455.
41. Rhoads K., Arderiu G., Charbonneau A., et al. A role for hoxa5 in regulating angiogenesis and vascular patterning. Lymphat Res Biol 2005, 3(4):240-252.
42. Volinia S., Calin G.A., Liu C.G., et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 2006, 103(7):2257-2261.
43. Hutvágner G., Simard M.J., Mello C.C., et al. Sequence-specific inhibition of small RNA function. PLoS Biol 2004, 2(4):E98.
44. Meister G., Landthaler M., Dorsett Y., et al. Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing. RNA 2004, 10(3):544-550.
45. Costinean S., Zanesi N., Pekarsky Y., et al. Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E (mu)-miR155 transgenic mice. Proc Natl Acad Sci USA 2006, 103(18):7024-7029.
46. Schwab R., Ossowski S., Riester M., et al. Highly specific gene silencing by artificial microRNAs in Arabidopsis. Plant Cell 2006, 18(5):1121-1133.
47. Krutzfeldt J., Rajewsky N., Braich R., et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature 2005, 438(7068):685-689.
48. Dickins R.A., Hemann M.T., Zilfou Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Nat Genet 2005, 37(1):1289-1295.
49. Henriett Butz, István Likó, Sándor Czirják, et al. MicroRNA profile indicates downregulation of the TGFβ pathway in sporadic non-functioning pituitary adenomas. Pituitary 2010, 1-13.