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Volumn 418, Issue 1, 2012, Pages 180-185

Quince (Cydonia oblonga Miller) peel polyphenols modulate LPS-induced inflammation in human THP-1-derived macrophages through NF-κB, p38MAPK and Akt inhibition

Author keywords

Cytokines; Inflammation; Macrophages; Polyphenols; Quince; Signalling pathways

Indexed keywords

ANTIINFLAMMATORY AGENT; CYDONIA OBLONGA EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 14; PLANT EXTRACT; POLYPHENOL DERIVATIVE; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84856433514     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.01.003     Document Type: Article
Times cited : (87)

References (43)
  • 1
    • 19644367000 scopus 로고    scopus 로고
    • Activation and signaling of the p38MAP kinase pathway
    • Zarubin T., Han J. Activation and signaling of the p38MAP kinase pathway. Cell. Res. 2005, 15:11-18.
    • (2005) Cell. Res. , vol.15 , pp. 11-18
    • Zarubin, T.1    Han, J.2
  • 2
    • 0033961280 scopus 로고    scopus 로고
    • Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB
    • Madrid L.V., Wang C.Y., Guttridge D.C., Schottelius A.J.G., Baldwin A.S., Mayo1 M.W. Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB. Mol. Cell. Biol. 2000, 20:1626-1638.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1626-1638
    • Madrid, L.V.1    Wang, C.Y.2    Guttridge, D.C.3    Schottelius, A.J.G.4    Baldwin, A.S.5    Mayo1, M.W.6
  • 3
    • 14044279871 scopus 로고    scopus 로고
    • Signal transduction pathways and transcription factors as therapeutic targets in inflammatory disease: towards innovative antirheumatic therapy, Curr. Pharm. Des.
    • S.W. Tas, P.H. Remans, K.A. Reedquist, P.P. Tak, Signal transduction pathways and transcription factors as therapeutic targets in inflammatory disease: towards innovative antirheumatic therapy, Curr. Pharm. Des. (2005) 581-611.
    • (2005) , pp. 581-611
    • Tas, S.W.1    Remans, P.H.2    Reedquist, K.A.3    Tak, P.P.4
  • 4
    • 33947358942 scopus 로고    scopus 로고
    • Therapeutic potential of phosphatidylinositol 3-kinase inhibitors in inflammatory respiratory disease
    • Ito K., Caramori G., Adcock I.M. Therapeutic potential of phosphatidylinositol 3-kinase inhibitors in inflammatory respiratory disease. J. Pharmacol. Exp. Ther. 2007, 321:1-8.
    • (2007) J. Pharmacol. Exp. Ther. , vol.321 , pp. 1-8
    • Ito, K.1    Caramori, G.2    Adcock, I.M.3
  • 5
    • 79251471130 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with tumour necrosis factor inhibitors
    • Mewar D., Wilson A.G. Treatment of rheumatoid arthritis with tumour necrosis factor inhibitors. Br. J. Phamacol. 2011, 162:785-791.
    • (2011) Br. J. Phamacol. , vol.162 , pp. 785-791
    • Mewar, D.1    Wilson, A.G.2
  • 6
    • 72249120832 scopus 로고    scopus 로고
    • The p38MAPK inhibitors for the treatment of inflammatory diseases and cancer
    • Yong H.Y., Koh M.S., Moon A. The p38MAPK inhibitors for the treatment of inflammatory diseases and cancer. Expert. Opin. Invest. Drugs 2009, 18:1893-1905.
    • (2009) Expert. Opin. Invest. Drugs , vol.18 , pp. 1893-1905
    • Yong, H.Y.1    Koh, M.S.2    Moon, A.3
  • 7
    • 0035139792 scopus 로고    scopus 로고
    • Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer
    • Yamamoto Y., Gaynor R.B. Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer. J. Clin. Invest. 2001, 107:135-142.
    • (2001) J. Clin. Invest. , vol.107 , pp. 135-142
    • Yamamoto, Y.1    Gaynor, R.B.2
  • 8
    • 0033594911 scopus 로고    scopus 로고
    • Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis
    • Warner T.D., Giuliano F., Vojnovic I., Bukasa A., Mitchell J.A., Vane J.R. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc. Natl. Acad. Sci. USA 1999, 96:7563-7568.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 7563-7568
    • Warner, T.D.1    Giuliano, F.2    Vojnovic, I.3    Bukasa, A.4    Mitchell, J.A.5    Vane, J.R.6
  • 10
    • 79955572744 scopus 로고    scopus 로고
    • Polyphenols as small molecular inhibitors of signaling cascades in carcinogenesis
    • Kang N.J., Shin S.H., Lee H.J., Lee K.W. Polyphenols as small molecular inhibitors of signaling cascades in carcinogenesis. Pharmacol. Ther. 2011, 130:310-324.
    • (2011) Pharmacol. Ther. , vol.130 , pp. 310-324
    • Kang, N.J.1    Shin, S.H.2    Lee, H.J.3    Lee, K.W.4
  • 11
    • 0037134637 scopus 로고    scopus 로고
    • Vitamin C equivalent antioxidant capacity (VCEAC) of phenolic phytochemicals
    • Kim D.O., Lee K.W., Lee H.J., Lee C.Y. Vitamin C equivalent antioxidant capacity (VCEAC) of phenolic phytochemicals. J. Agric. Food. Chem. 2002, 50:3713-3717.
    • (2002) J. Agric. Food. Chem. , vol.50 , pp. 3713-3717
    • Kim, D.O.1    Lee, K.W.2    Lee, H.J.3    Lee, C.Y.4
  • 12
    • 0343458043 scopus 로고    scopus 로고
    • Antioxidant activity of fresh apples
    • Eberhardt M.V., Lee C.Y., Liu R.H. Antioxidant activity of fresh apples. Nature 2000, 405:903-904.
    • (2000) Nature , vol.405 , pp. 903-904
    • Eberhardt, M.V.1    Lee, C.Y.2    Liu, R.H.3
  • 13
    • 0018108539 scopus 로고
    • Activated oxygen species and oxidation of food constituents, CRC
    • Korycka-Dahl M.B., Richardson T. Activated oxygen species and oxidation of food constituents, CRC. Crit. Rev. Food. Sci. Nutr. 1978, 10:209-241.
    • (1978) Crit. Rev. Food. Sci. Nutr. , vol.10 , pp. 209-241
    • Korycka-Dahl, M.B.1    Richardson, T.2
  • 14
    • 0032842152 scopus 로고    scopus 로고
    • Evaluation of radical scavenging activity of fresh and air-dried tomatoes by three model reactions
    • Lavelli V., Hippeli S., Peri C., Elstner E.F. Evaluation of radical scavenging activity of fresh and air-dried tomatoes by three model reactions. J. Agri. Food. Chem. 1999, 47:3826-3831.
    • (1999) J. Agri. Food. Chem. , vol.47 , pp. 3826-3831
    • Lavelli, V.1    Hippeli, S.2    Peri, C.3    Elstner, E.F.4
  • 17
    • 77649267205 scopus 로고    scopus 로고
    • The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages
    • Daigneault M., Preston J.A., Mariott H.M., Whyte M.K., Dockrell D.H. The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages. PLoS One 2010, 5:e8668.
    • (2010) PLoS One , vol.5
    • Daigneault, M.1    Preston, J.A.2    Mariott, H.M.3    Whyte, M.K.4    Dockrell, D.H.5
  • 18
    • 28044446082 scopus 로고    scopus 로고
    • Development of an in vitro screening assay to test the anti-inflammatory properties of dietary supplements and pharmacologic agents
    • Singh U., Tabibian J., Venugopal S.K., Devaraj S., Jialal I. Development of an in vitro screening assay to test the anti-inflammatory properties of dietary supplements and pharmacologic agents. Clin. Chem. 2005, 51:2256.
    • (2005) Clin. Chem. , vol.51 , pp. 2256
    • Singh, U.1    Tabibian, J.2    Venugopal, S.K.3    Devaraj, S.4    Jialal, I.5
  • 19
    • 0001929693 scopus 로고    scopus 로고
    • Cytokines in acute and chronic inflammation
    • Feghali C.A., Wright T.M. Cytokines in acute and chronic inflammation. Front. Biosci. 1997, 2:d12-d26.
    • (1997) Front. Biosci. , vol.2
    • Feghali, C.A.1    Wright, T.M.2
  • 20
    • 0026095304 scopus 로고
    • Regulation of transendothelial neutrophil migration by endogenous interleukin-8
    • Huber A.R., Kundel S.L., Todd R.F. Regulation of transendothelial neutrophil migration by endogenous interleukin-8. Science 1991, 254:99-102.
    • (1991) Science , vol.254 , pp. 99-102
    • Huber, A.R.1    Kundel, S.L.2    Todd, R.F.3
  • 21
    • 79957927386 scopus 로고    scopus 로고
    • Anti-TNF therapy: safety aspects of taking the risk
    • Rosenblum H., Amital H. Anti-TNF therapy: safety aspects of taking the risk. Autoimmun. Rev. 2011, 10:563-568.
    • (2011) Autoimmun. Rev. , vol.10 , pp. 563-568
    • Rosenblum, H.1    Amital, H.2
  • 22
    • 0033594911 scopus 로고    scopus 로고
    • Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis
    • Warner T.D., Giualiano F., Vojnovic I., Bukasa A., Mitchell J.A., Vane J.R. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc. Natl. Acad. Sci. USA 1999, 96:7563-7568.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 7563-7568
    • Warner, T.D.1    Giualiano, F.2    Vojnovic, I.3    Bukasa, A.4    Mitchell, J.A.5    Vane, J.R.6
  • 23
    • 79953048089 scopus 로고    scopus 로고
    • Regulation and functions of the IL-10 family of cytokines in inflammation and disease
    • Ouyang W., Rutz S., Crellin N.K., Valdez P.A., Hymowitz S.G. Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annu. Rev. Immunol. 2011, 29:71-109.
    • (2011) Annu. Rev. Immunol. , vol.29 , pp. 71-109
    • Ouyang, W.1    Rutz, S.2    Crellin, N.K.3    Valdez, P.A.4    Hymowitz, S.G.5
  • 24
    • 0026094306 scopus 로고
    • Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes
    • de Waal Malefyt R., Abrams J., Bennett B., Figdor C.G., de Vries J.E. Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Ex. Med. 1991, 174:1209-1220.
    • (1991) J. Ex. Med. , vol.174 , pp. 1209-1220
    • de Waal Malefyt, R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    de Vries, J.E.5
  • 25
    • 0036224092 scopus 로고    scopus 로고
    • Immunomodulation by interleukin-10 therapy decreases the incidence of relapse and prolongs the relapse-free interval in Psoriasis
    • Friedrich M., Döcke W.D., Klein A., Philipp S., Volk H.D., Sterry W., Asadullah K. Immunomodulation by interleukin-10 therapy decreases the incidence of relapse and prolongs the relapse-free interval in Psoriasis. J. Invest. Dermatol. 2002, 118:672-677.
    • (2002) J. Invest. Dermatol. , vol.118 , pp. 672-677
    • Friedrich, M.1    Döcke, W.D.2    Klein, A.3    Philipp, S.4    Volk, H.D.5    Sterry, W.6    Asadullah, K.7
  • 26
    • 79952052483 scopus 로고    scopus 로고
    • Recombinant human interleukin-10 for induction of remission in Crohn's disease, Cochrane, Database. Syst. Rev. 11 CD005109.
    • F.E. Buruiana, I. Solà, P. Alonso-Coello, Recombinant human interleukin-10 for induction of remission in Crohn's disease, Cochrane, Database. Syst. Rev. 11 (2010) CD005109.
    • (2010)
    • Buruiana, F.E.1    Solà, I.2    Alonso-Coello, P.3
  • 27
    • 0026333033 scopus 로고
    • Interleukin-6 and its relation to inflammation and disease
    • Hirano T. Interleukin-6 and its relation to inflammation and disease. Clin. Immunol. Immunopathol. 1992, 62:S60-S65.
    • (1992) Clin. Immunol. Immunopathol. , vol.62
    • Hirano, T.1
  • 28
    • 0025696119 scopus 로고
    • Expression of the interleukin 6 gene in rheumatoid synovial fibroblasts
    • Tan P.L., Farmiloe S., Yeoman S., Watson J.D. Expression of the interleukin 6 gene in rheumatoid synovial fibroblasts. J. Rheumatol. 1990, 17:1608-1612.
    • (1990) J. Rheumatol. , vol.17 , pp. 1608-1612
    • Tan, P.L.1    Farmiloe, S.2    Yeoman, S.3    Watson, J.D.4
  • 29
    • 0025176658 scopus 로고
    • Correlations and interactions in the production of interleukin-6, IL-1, and tumor necrosis factor in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF
    • Schindler R., Mancilla J., Endres S., Ghorbani R., Clark S.C., Dinarello C.A. Correlations and interactions in the production of interleukin-6, IL-1, and tumor necrosis factor in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF. Blood 1990, 75:40-47.
    • (1990) Blood , vol.75 , pp. 40-47
    • Schindler, R.1    Mancilla, J.2    Endres, S.3    Ghorbani, R.4    Clark, S.C.5    Dinarello, C.A.6
  • 30
    • 0038322493 scopus 로고    scopus 로고
    • Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans
    • Starkie R., Ostrowiski S.R., Jauffred S., Febbraio M., Pedersen B.K. Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans. FASEB J. 2003, 17:884-886.
    • (2003) FASEB J. , vol.17 , pp. 884-886
    • Starkie, R.1    Ostrowiski, S.R.2    Jauffred, S.3    Febbraio, M.4    Pedersen, B.K.5
  • 31
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappaB and I kappa-B proteins: new discoveries and insights
    • Baldwin A.S. The NF-kappaB and I kappa-B proteins: new discoveries and insights. Annu. Rev. Immunol. 1996, 14:649-683.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 649-683
    • Baldwin, A.S.1
  • 32
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-kappaB puzzle
    • Ghosh S., Karin M. Missing pieces in the NF-kappaB puzzle. Cell 2002, 109:S81-S96.
    • (2002) Cell , vol.109
    • Ghosh, S.1    Karin, M.2
  • 34
    • 0030805596 scopus 로고    scopus 로고
    • Expression of mitogen-inducible cyclooxygenase induced by lipopolysaccharide: mediation through both mitogen-activated protein kinase and NF-kappaB signaling pathways in macrophages
    • Hwang D., Jang B.C., Yu G., Boudreau M. Expression of mitogen-inducible cyclooxygenase induced by lipopolysaccharide: mediation through both mitogen-activated protein kinase and NF-kappaB signaling pathways in macrophages. Biochem. Pharmacol. 1997, 54:87-96.
    • (1997) Biochem. Pharmacol. , vol.54 , pp. 87-96
    • Hwang, D.1    Jang, B.C.2    Yu, G.3    Boudreau, M.4
  • 35
    • 0034668121 scopus 로고    scopus 로고
    • Protein kinase C zeta plays a central role in activation of the p42/44 mitogen-activated protein kinase by endotoxin in alveolar macrophages
    • Monick M.M., Carter A.B., Flaherty D.M., Peterson M.W., Hunninghake G.W. Protein kinase C zeta plays a central role in activation of the p42/44 mitogen-activated protein kinase by endotoxin in alveolar macrophages. J. Immunol. 2000, 165:4632-4639.
    • (2000) J. Immunol. , vol.165 , pp. 4632-4639
    • Monick, M.M.1    Carter, A.B.2    Flaherty, D.M.3    Peterson, M.W.4    Hunninghake, G.W.5
  • 36
    • 0035313040 scopus 로고    scopus 로고
    • Lipopolysaccharide activates Akt in human alveolar macrophages resulting in nuclear accumulation and transcriptional activity of beta-catenin
    • Monick M.M., Carter A.B., Robeff P.K., Flaherty D.M., Peterson M.W., Hunninghake G.W. Lipopolysaccharide activates Akt in human alveolar macrophages resulting in nuclear accumulation and transcriptional activity of beta-catenin. J. Immunol. 2001, 166:4713-4720.
    • (2001) J. Immunol. , vol.166 , pp. 4713-4720
    • Monick, M.M.1    Carter, A.B.2    Robeff, P.K.3    Flaherty, D.M.4    Peterson, M.W.5    Hunninghake, G.W.6
  • 37
    • 79958043464 scopus 로고    scopus 로고
    • Catechin suppresses an array of signalling molecules and modulates alcohol-induced endotoxin mediated liver injury in a rat model
    • Koul S.A., Chopra K., Rishi P. Catechin suppresses an array of signalling molecules and modulates alcohol-induced endotoxin mediated liver injury in a rat model. PLoS One 2011, 6:e20635.
    • (2011) PLoS One , vol.6
    • Koul, S.A.1    Chopra, K.2    Rishi, P.3
  • 38
    • 67649427457 scopus 로고    scopus 로고
    • The effects of dietary curcumin and rutin on colonic inflammation and gene expression in multidrug resistance gene-deficient (mdr1a-/-) mice, a model of inflammatory bowel diseases
    • Nones K., Dommels Y.E., Martell S., et al. The effects of dietary curcumin and rutin on colonic inflammation and gene expression in multidrug resistance gene-deficient (mdr1a-/-) mice, a model of inflammatory bowel diseases. Br. J. Nutr. 2009, 101:169-181.
    • (2009) Br. J. Nutr. , vol.101 , pp. 169-181
    • Nones, K.1    Dommels, Y.E.2    Martell, S.3
  • 39
    • 58249128687 scopus 로고    scopus 로고
    • Rutin has therapeutic effect on septic arthritis caused by Candida albicans
    • Han Y. Rutin has therapeutic effect on septic arthritis caused by Candida albicans. Int. Immunopharmacol. 2009, 9:207-211.
    • (2009) Int. Immunopharmacol. , vol.9 , pp. 207-211
    • Han, Y.1
  • 40
    • 57349117995 scopus 로고    scopus 로고
    • Effects of hyperin, isoquercitrin and quercetin on lipopolysaccharide-induced nitrite production in rat peritoneal macrophages
    • Lee S., Park H.S., Notsu Y., et al. Effects of hyperin, isoquercitrin and quercetin on lipopolysaccharide-induced nitrite production in rat peritoneal macrophages. Phytother. Res. 2008, 22:1552-1556.
    • (2008) Phytother. Res. , vol.22 , pp. 1552-1556
    • Lee, S.1    Park, H.S.2    Notsu, Y.3
  • 41
    • 79952650342 scopus 로고    scopus 로고
    • Procyanidin dimer B1 and trimer C1 impair inflammatory response signalling in human monocytes
    • Terra X., Palozza P., Fernandez-Larrea J., et al. Procyanidin dimer B1 and trimer C1 impair inflammatory response signalling in human monocytes. Free Radic. Res. 2011, 45:611-619.
    • (2011) Free Radic. Res. , vol.45 , pp. 611-619
    • Terra, X.1    Palozza, P.2    Fernandez-Larrea, J.3
  • 42
    • 79958050043 scopus 로고    scopus 로고
    • Chlorogenic acids from Tithonia diversifolia demonstrate better anti-inflammatory effect than indomethacin and its sesquiterpene lactones
    • Chagas-Paula D.A., Oliveira R.B., da Silva V.C., et al. Chlorogenic acids from Tithonia diversifolia demonstrate better anti-inflammatory effect than indomethacin and its sesquiterpene lactones. J. Ethnopharmacol. 2011, 136:355-362.
    • (2011) J. Ethnopharmacol. , vol.136 , pp. 355-362
    • Chagas-Paula, D.A.1    Oliveira, R.B.2    da Silva, V.C.3
  • 43
    • 84862907830 scopus 로고    scopus 로고
    • Kaempferol suppresses eosinophil infiltration and airway inflammation in airway epithelial cells and in mice with allergic asthma
    • Gong J.H., Shin D., Han S.Y., Kim J.L., Kang Y.H. Kaempferol suppresses eosinophil infiltration and airway inflammation in airway epithelial cells and in mice with allergic asthma. J. Nutr. 2012, 142:47-56.
    • (2012) J. Nutr. , vol.142 , pp. 47-56
    • Gong, J.H.1    Shin, D.2    Han, S.Y.3    Kim, J.L.4    Kang, Y.H.5


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