-
1
-
-
0027263181
-
Clinical significance of P-glycoprotein in multidrug resistance malignancies
-
Arceci RJ (1993) Clinical significance of P-glycoprotein in multidrug resistance malignancies. Blood 81: 2215-2222.
-
(1993)
Blood
, vol.81
, pp. 2215-2222
-
-
Arceci, R.J.1
-
2
-
-
16644393213
-
The PIK3CA gene is mutated with high frequency in human breast cancers
-
Bachman KE, Argani P, Samuels Y et al (2004) The PIK3CA gene is mutated with high frequency in human breast cancers. Cancer Biol Ther 3: 772-775.
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 772-775
-
-
Bachman, K.E.1
Argani, P.2
Samuels, Y.3
-
3
-
-
52449106497
-
Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: A Children's Oncology Group Study
-
Bhojwani D, Kang H, Menezes RX et al (2008) Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: A Children's Oncology Group Study. J Clin Oncol 26: 4376-4384.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4376-4384
-
-
Bhojwani, D.1
Kang, H.2
Menezes, R.X.3
-
5
-
-
78650776871
-
Phylogenomics of phosphoinositide lipid kinases: perspectives on the evolution of second messenger signaling and drug discovery
-
Brown JR, Auger KR (2011) Phylogenomics of phosphoinositide lipid kinases: perspectives on the evolution of second messenger signaling and drug discovery. BMC Evol Biol 11: 4.
-
(2011)
BMC Evol Biol
, vol.11
, pp. 4
-
-
Brown, J.R.1
Auger, K.R.2
-
6
-
-
0037738513
-
Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells
-
Cheok MH, Yang W, Pui CH et al (2003) Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells. Nat Genet 34: 85-90.
-
(2003)
Nat Genet
, vol.34
, pp. 85-90
-
-
Cheok, M.H.1
Yang, W.2
Pui, C.H.3
-
7
-
-
0032521241
-
Relationship between major vault protein/lung resistance protein, multidrug resistance-associated protein, P-glycoprotein expression, and drug resistance in childhood leukemia
-
den Boer ML, Pieters R, Kazemier KM et al (1998) Relationship between major vault protein/lung resistance protein, multidrug resistance-associated protein, P-glycoprotein expression, and drug resistance in childhood leukemia. Blood 91: 2092-2098.
-
(1998)
Blood
, vol.91
, pp. 2092-2098
-
-
den Boer, M.L.1
Pieters, R.2
Kazemier, K.M.3
-
8
-
-
0141799965
-
Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia
-
den Boer ML, Harms DO, Pieters R et al (2003) Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia. J Clin Oncol 21: 3262-3268.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3262-3268
-
-
den Boer, M.L.1
Harms, D.O.2
Pieters, R.3
-
9
-
-
2642570170
-
Moving towards individualized medicine with pharmacogenomics
-
Evans WE, Relling MV (2004) Moving towards individualized medicine with pharmacogenomics. Nature 429: 464-468.
-
(2004)
Nature
, vol.429
, pp. 464-468
-
-
Evans, W.E.1
Relling, M.V.2
-
10
-
-
17144474314
-
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
-
Ferrando AA, Neuberg DS, Staunton J et al (2002) Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell 1: 75-87.
-
(2002)
Cancer Cell
, vol.1
, pp. 75-87
-
-
Ferrando, A.A.1
Neuberg, D.S.2
Staunton, J.3
-
11
-
-
11344292817
-
Association of gastric cancer, HLA-DQA1, and infection with Helicobacter pylori CagA+ and VacA+ in a Mexican population
-
Garza-González E, Bosques-Padilla FJ, Pérez-Pérez GI et al (2004) Association of gastric cancer, HLA-DQA1, and infection with Helicobacter pylori CagA+ and VacA+ in a Mexican population. J Gastroenterol 39: 1138-1142.
-
(2004)
J Gastroenterol
, vol.39
, pp. 1138-1142
-
-
Garza-González, E.1
Bosques-Padilla, F.J.2
Pérez-Pérez, G.I.3
-
12
-
-
33644871737
-
Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations
-
Györffy B, Surowiak P, Kiesslich O et al (2006) Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations. Int J Cancer 118: 1699-1712.
-
(2006)
Int J Cancer
, vol.118
, pp. 1699-1712
-
-
Györffy, B.1
Surowiak, P.2
Kiesslich, O.3
-
14
-
-
0037045589
-
Relation between resistance of Philadelphia-chromosome-positive acute lymphoblastic leukaemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: a gene-expression study
-
Hofmann WK, de Vos S, Elashoff D et al (2002) Relation between resistance of Philadelphia-chromosome-positive acute lymphoblastic leukaemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: a gene-expression study. Lancet 359: 481-486.
-
(2002)
Lancet
, vol.359
, pp. 481-486
-
-
Hofmann, W.K.1
de Vos, S.2
Elashoff, D.3
-
15
-
-
3543054544
-
Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment
-
Holleman A, Cheok MH, den Boer ML et al (2004) Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment. N Engl J Med 351: 533-542.
-
(2004)
N Engl J Med
, vol.351
, pp. 533-542
-
-
Holleman, A.1
Cheok, M.H.2
den Boer, M.L.3
-
16
-
-
30444446961
-
The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia
-
Holleman A, den Boer ML, de Menezes RX et al (2006) The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia. Blood 107: 769-776.
-
(2006)
Blood
, vol.107
, pp. 769-776
-
-
Holleman, A.1
den Boer, M.L.2
de Menezes, R.X.3
-
17
-
-
21144457217
-
Functional analysis of PIK3CA gene mutations in human colorectal cancer
-
Ikenoue T, Kanai F, Hikiba Y et al (2005) Functional analysis of PIK3CA gene mutations in human colorectal cancer. Cancer Res 65: 4562-4567.
-
(2005)
Cancer Res
, vol.65
, pp. 4562-4567
-
-
Ikenoue, T.1
Kanai, F.2
Hikiba, Y.3
-
18
-
-
33644980008
-
DNA microarrays and papillary thyroid carcinoma gene expression profile
-
Jarzab B, Gubała E, Lange D (2005) DNA microarrays and papillary thyroid carcinoma gene expression profile. Endokrynol Pol 56: 293-301.
-
(2005)
Endokrynol Pol
, vol.56
, pp. 293-301
-
-
Jarzab, B.1
Gubała, E.2
Lange, D.3
-
19
-
-
70349756898
-
Risk-adapted treatment of pediatric acute lymphoblastic leukemia
-
Jeha S, Pui CH (2009) Risk-adapted treatment of pediatric acute lymphoblastic leukemia. Hematol Oncol Clin North Am 23: 973-990.
-
(2009)
Hematol Oncol Clin North Am
, vol.23
, pp. 973-990
-
-
Jeha, S.1
Pui, C.H.2
-
20
-
-
20244377046
-
Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia
-
Lugthart S, Cheok MH, den Boer ML et al (2005) Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia. Cancer Cell 7: 375-386.
-
(2005)
Cancer Cell
, vol.7
, pp. 375-386
-
-
Lugthart, S.1
Cheok, M.H.2
den Boer, M.L.3
-
21
-
-
30744470374
-
The Nudix hydrolase superfamily
-
McLennan AG (2006) The Nudix hydrolase superfamily. Cell Mol Life Sci 63: 123-143.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 123-143
-
-
McLennan, A.G.1
-
23
-
-
47149100125
-
Risk-adjusted therapy of acute lymphoblastic leukemia can decrease treatment burden and improve survival: treatment results of 2169 unselected pediatric and adolescent patients enrolled in the trial ALL-BFM 95
-
Möricke A, Reiter A, Zimmermann M et al (2008) Risk-adjusted therapy of acute lymphoblastic leukemia can decrease treatment burden and improve survival: treatment results of 2169 unselected pediatric and adolescent patients enrolled in the trial ALL-BFM 95. Blood 111: 4477-4489.
-
(2008)
Blood
, vol.111
, pp. 4477-4489
-
-
Möricke, A.1
Reiter, A.2
Zimmermann, M.3
-
24
-
-
76749102418
-
Long-term results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000
-
Möricke A, Zimmermann M, Reiter A et al (2010) Long-term results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000. Leukemia 24: 265-284.
-
(2010)
Leukemia
, vol.24
, pp. 265-284
-
-
Möricke, A.1
Zimmermann, M.2
Reiter, A.3
-
25
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45.
-
(2001)
Nucleic Acids Res
, vol.29
-
-
Pfaffl, M.W.1
-
26
-
-
33644893065
-
HLA class II polymorphisms in Spanish melanoma patients: homozygosity for HLA-DQA1 locus can be a potential melanoma risk factor
-
Planelles D, Nagore E, Moret A et al (2006) HLA class II polymorphisms in Spanish melanoma patients: homozygosity for HLA-DQA1 locus can be a potential melanoma risk factor. Br J Dermatol 154: 261-266.
-
(2006)
Br J Dermatol
, vol.154
, pp. 261-266
-
-
Planelles, D.1
Nagore, E.2
Moret, A.3
-
27
-
-
70449700006
-
Toward a total cure for acute lymphoblastic leukemia
-
Pui CH (2009) Toward a total cure for acute lymphoblastic leukemia. J Clin Oncol 27: 5121-5123.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5121-5123
-
-
Pui, C.H.1
-
28
-
-
67649410242
-
Treating childhood acute lymphoblastic leukemia without cranial irradiation
-
Pui CH, Campana D, Pei D et al (2009) Treating childhood acute lymphoblastic leukemia without cranial irradiation. N Engl J Med 360: 2730-2741.
-
(2009)
N Engl J Med
, vol.360
, pp. 2730-2741
-
-
Pui, C.H.1
Campana, D.2
Pei, D.3
-
29
-
-
0034669309
-
Extensive genetic alterations of the HLA region, including homozygous deletions of HLA class II genes in B-cell lymphomas arising in immune-privileged sites
-
Riemersma SA, Jordanova ES, Schop RF et al (2000) Extensive genetic alterations of the HLA region, including homozygous deletions of HLA class II genes in B-cell lymphomas arising in immune-privileged sites. Blood 96: 3569-3577.
-
(2000)
Blood
, vol.96
, pp. 3569-3577
-
-
Riemersma, S.A.1
Jordanova, E.S.2
Schop, R.F.3
-
30
-
-
33646706052
-
Oncogenic PI3K and its role in cancer
-
Samuels Y, Ericson K (2006) Oncogenic PI3K and its role in cancer. Curr Opin Oncol 18: 77-82.
-
(2006)
Curr Opin Oncol
, vol.18
, pp. 77-82
-
-
Samuels, Y.1
Ericson, K.2
-
31
-
-
11144358645
-
High frequency of mutations of the PIK3CA gene in human cancers
-
Samuels Y, Wang Z, Bardelli A et al (2004) High frequency of mutations of the PIK3CA gene in human cancers. Science 304: 554.
-
(2004)
Science
, vol.304
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
-
32
-
-
84856758666
-
MicroRNAs in acute leukemia: from biological players to clinical contributors
-
(in press). doi: 10. 1038/leu. 2011. 151
-
Schotte D, Pieters R, Den Boer ML (2011a) MicroRNAs in acute leukemia: from biological players to clinical contributors. Leukemia (in press). doi: 10. 1038/leu. 2011. 151.
-
(2011)
Leukemia
-
-
Schotte, D.1
Pieters, R.2
Den Boer, M.L.3
-
33
-
-
79955716719
-
MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia
-
Schotte D, De Menezes RX, Moqadam FA et al (2011b) MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia. Haematologica 96: 703-711.
-
(2011)
Haematologica
, vol.96
, pp. 703-711
-
-
Schotte, D.1
de Menezes, R.X.2
Moqadam, F.A.3
-
34
-
-
78649801874
-
Profiling of regulatory microRNA transcriptomes in various biological processes: a review
-
Shah AA, Meese E, Blin N (2010) Profiling of regulatory microRNA transcriptomes in various biological processes: a review. J Appl Genet 51: 501-507.
-
(2010)
J Appl Genet
, vol.51
, pp. 501-507
-
-
Shah, A.A.1
Meese, E.2
Blin, N.3
-
35
-
-
77949424325
-
Genome-wide expression analysis of paired diagnosis-relapse samples in ALL indicates involvement of pathways related to DNA replication, cell cycle and DNA repair, independent of immune phenotype
-
Staal FJ, de Ridder D, Szczepanski T et al (2010) Genome-wide expression analysis of paired diagnosis-relapse samples in ALL indicates involvement of pathways related to DNA replication, cell cycle and DNA repair, independent of immune phenotype. Leukemia 24: 491-499.
-
(2010)
Leukemia
, vol.24
, pp. 491-499
-
-
Staal, F.J.1
de Ridder, D.2
Szczepanski, T.3
-
36
-
-
1542503701
-
Is the in vitro drug resistance profile the strongest prognostic factor in childhood acute lymphoblastic leukemia?
-
Styczyński J, Wysocki M (2004) Is the in vitro drug resistance profile the strongest prognostic factor in childhood acute lymphoblastic leukemia? J Clin Oncol 22: 963-964.
-
(2004)
J Clin Oncol
, vol.22
, pp. 963-964
-
-
Styczyński, J.1
Wysocki, M.2
-
37
-
-
0033760960
-
In vitro drug resistance profiles of adult versus childhood acute lymphoblastic leukaemia
-
Styczynski J, Pieters R, Huismans DR et al (2000) In vitro drug resistance profiles of adult versus childhood acute lymphoblastic leukaemia. Br J Haematol 110: 813-818.
-
(2000)
Br J Haematol
, vol.110
, pp. 813-818
-
-
Styczynski, J.1
Pieters, R.2
Huismans, D.R.3
-
38
-
-
6444245237
-
Ex vivo drug resistance profile in childhood acute myelogenous leukemia: no drug is more effective in comparison to acute lymphoblastic leukemia
-
Styczynski J, Wysocki M, Debski R et al (2002) Ex vivo drug resistance profile in childhood acute myelogenous leukemia: no drug is more effective in comparison to acute lymphoblastic leukemia. Leuk Lymphoma 43: 1843-1848.
-
(2002)
Leuk Lymphoma
, vol.43
, pp. 1843-1848
-
-
Styczynski, J.1
Wysocki, M.2
Debski, R.3
-
39
-
-
45949090607
-
Prognostic impact of combined fludarabine, treosulfan and mitoxantrone resistance profile in childhood acute myeloid leukemia
-
Styczynski J, Wysocki M, Dluzniewska A et al (2008) Prognostic impact of combined fludarabine, treosulfan and mitoxantrone resistance profile in childhood acute myeloid leukemia. Anticancer Res 28: 1927-1931.
-
(2008)
Anticancer Res
, vol.28
, pp. 1927-1931
-
-
Styczynski, J.1
Wysocki, M.2
Dluzniewska, A.3
-
40
-
-
36149001396
-
Gene expression profiles in acute lymphoblastic leukemia in children and adults
-
Szczepanek J, Styczyński J, Haus O et al (2007) Gene expression profiles in acute lymphoblastic leukemia in children and adults. Postepy Hig Med Dosw (Online) 61: 519-533.
-
(2007)
Postepy Hig Med Dosw (Online)
, vol.61
, pp. 519-533
-
-
Szczepanek, J.1
Styczyński, J.2
Haus, O.3
-
41
-
-
0037358040
-
Overcoming multidrug resistance in cancer: an update on the clinical strategy of inhibiting p-glycoprotein
-
Thomas H, Coley HM (2003) Overcoming multidrug resistance in cancer: an update on the clinical strategy of inhibiting p-glycoprotein. Cancer Control 10: 159-165.
-
(2003)
Cancer Control
, vol.10
, pp. 159-165
-
-
Thomas, H.1
Coley, H.M.2
-
42
-
-
0034012773
-
The prognostic significance of membrane transport-associated multidrug resistance (MDR) proteins in leukemia
-
van den Heuvel-Eibrink MM, Sonneveld P, Pieters R (2000) The prognostic significance of membrane transport-associated multidrug resistance (MDR) proteins in leukemia. Int J Clin Pharmacol Ther 38: 94-110.
-
(2000)
Int J Clin Pharmacol Ther
, vol.38
, pp. 94-110
-
-
van den Heuvel-Eibrink, M.M.1
Sonneveld, P.2
Pieters, R.3
-
43
-
-
0037461959
-
RhoG regulates gene expression and the actin cytoskeleton in lymphocytes
-
Vigorito E, Billadeu DD, Savoy D et al (2003) RhoG regulates gene expression and the actin cytoskeleton in lymphocytes. Oncogene 22: 330-342.
-
(2003)
Oncogene
, vol.22
, pp. 330-342
-
-
Vigorito, E.1
Billadeu, D.D.2
Savoy, D.3
-
44
-
-
65249150218
-
Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway
-
Vilar E, Mukherjee B, Kuick R et al (2009) Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway. Clin Cancer Res 15: 2829-2839.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2829-2839
-
-
Vilar, E.1
Mukherjee, B.2
Kuick, R.3
-
45
-
-
3142757248
-
Prediction of immunophenotype, treatment response, and relapse in childhood acute lymphoblastic leukemia using DNA microarrays
-
Willenbrock H, Juncker AS, Schmiegelow K et al (2004) Prediction of immunophenotype, treatment response, and relapse in childhood acute lymphoblastic leukemia using DNA microarrays. Leukemia 18: 1270-1277.
-
(2004)
Leukemia
, vol.18
, pp. 1270-1277
-
-
Willenbrock, H.1
Juncker, A.S.2
Schmiegelow, K.3
-
46
-
-
19044399684
-
Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling
-
Yeoh EJ, Ross ME, Shurtleff SA et al (2002) Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell 1: 133-143.
-
(2002)
Cancer Cell
, vol.1
, pp. 133-143
-
-
Yeoh, E.J.1
Ross, M.E.2
Shurtleff, S.A.3
-
47
-
-
23944500840
-
Gene expression and thioguanine nucleotide disposition in acute lymphoblastic leukemia after in vivo mercaptopurine treatment
-
Zaza G, Cheok M, Yang W et al (2005) Gene expression and thioguanine nucleotide disposition in acute lymphoblastic leukemia after in vivo mercaptopurine treatment. Blood 106: 1778-1785.
-
(2005)
Blood
, vol.106
, pp. 1778-1785
-
-
Zaza, G.1
Cheok, M.2
Yang, W.3
|