Atorvastatin reduces vascular endothelial growth factor (VEGF) expression in human non-small cell lung carcinomas (NSCLCs) via inhibition of reactive oxygen species (ROS) production

Molecular Oncology

Volumn 6, Issue 1, 2012, Pages 62-72

  Chen, Jie ^a   Liu, Bing ^b   Yuan, Jiayi ^a   Yang, Jie ^c   Zhang, Jingjie ^a   An, Yu ^a   Tie, Lu ^a   Pan, Yan ^a   Li, Xuejun ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

^c GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Atorvastatin; NADPH oxidase; Non small cell lung cancers; NSCLCS; Reactive oxygen species; ROS; Vascular endothelial growth factor; VEGF

Indexed keywords

ATORVASTATIN; CATALASE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG INHIBITION; ELIMINATION REACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; IN VIVO STUDY; LUNG NON SMALL CELL CANCER; MITOCHONDRION; MOUSE; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; UPREGULATION; WESTERN BLOTTING;

EID: 84856280739     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2011.11.003     Document Type: Article

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