Hypokinesia and reduced dopamine levels in zebrafish lacking β- and γ1-synucleins

Journal of Biological Chemistry

Volumn 287, Issue 5, 2012, Pages 2971-2983

  Milanese, Chiara ^a,b   Sager, Jonathan J ^a   Bais, Qing ^a   Farrells, Thomas C ^a   Cannons, Jason R ^a   Greenamyre, J Timothy ^a,c   Burtons, Edward A ^a,c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b RiMED Foundation   (Italy)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINERGIC NEURONS; EXPRESSION PATTERNS; IN-VIVO; MOLECULAR PHYSIOLOGY; MOTOR ACTIVITY; MOTOR BEHAVIOR; NEURONAL FUNCTION; NORMAL FUNCTION; PARKINSON DISEASE; PATHOPHYSIOLOGY; PHENOTYPIC ABNORMALITIES; PHYLOGENETIC CONSERVATION; SYNUCLEIN; ZEBRAFISH;

ANIMALS; BRAIN; DISEASES; GENE EXPRESSION; NEURONS; PHYSIOLOGY;

PHYSIOLOGICAL MODELS;

BETA SYNUCLEIN; DOPAMINE; GAMMA SYNUCLEIN; GAMMA1 SYNUCLEIN; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY BUILD; CATECHOLAMINE NERVE CELL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEVELOPMENTAL GENE; DEVELOPMENTAL STAGE; DISEASE SEVERITY; DOPAMINE BRAIN LEVEL; DOPAMINERGIC NERVE CELL; EMBRYO; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE LOCATION; GENE LOSS; GENETIC CONSERVATION; HYPOKINESIA; IN VIVO STUDY; LARVAL DEVELOPMENT; MOTOR PERFORMANCE; NERVE CELL DIFFERENTIATION; NEUROPATHOLOGY; NONHUMAN; PARKINSON DISEASE; PHYLOGENY; PRIORITY JOURNAL; SNCB GENE; SNCG1 GENE; SNCG2 GENE; TISSUE DISTRIBUTION;

ALPHA-SYNUCLEIN; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BETA-SYNUCLEIN; CELL DIFFERENTIATION; DOPAMINE; DOPAMINERGIC NEURONS; GAMMA-SYNUCLEIN; HUMANS; IMMOBILIZATION; MOTOR ACTIVITY; PHYLOGENY; RNA, MESSENGER; ZEBRAFISH; ZEBRAFISH PROTEINS;

ANIMALIA; DANIO RERIO;

EID: 84856250576     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.308312     Document Type: Article

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