RASSF1A and the BH3-only mimetic ABT-737 promote apoptosis in pediatric medulloblastoma cell lines

Neuro-Oncology

Volumn 13, Issue 12, 2011, Pages 1265-1276

  Levesley, Jane ^a   Lusher, Meryl E ^b   Lindsey, Janet C ^b   Clifford, Steven C ^b   Grundy, Richard ^a   Coyle, Beth ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

ABT 737; Apoptosis; Medulloblastoma; RASSF1A; Therapy.

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; BH3 PROTEIN; CISPLATIN; ETOPOSIDE; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; EPIGENETICS; HUMAN; MEDULLOBLASTOMA; MOUSE; NONHUMAN; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BIPHENYL COMPOUNDS; BLOTTING, WESTERN; CASPASES; CELL LINE, TUMOR; CEREBELLAR NEOPLASMS; CHILD; CISPLATIN; ETOPOSIDE; HUMANS; IMMUNOENZYME TECHNIQUES; MEDULLOBLASTOMA; NITROPHENOLS; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-BCL-2; SULFONAMIDES; TUMOR SUPPRESSOR PROTEINS;

EID: 84856239462     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nor129     Document Type: Article

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