메뉴 건너뛰기




Volumn 10, Issue 7, 2008, Pages 736-744

Inhibition of STAT3 expression and signaling in resveratrol-differentiated medulloblastoma cells

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; CYCLOOXYGENASE 2; LEUKEMIA INHIBITORY FACTOR; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PROTEIN BCL 2; RESVERATROL; STAT3 PROTEIN; SURVIVIN;

EID: 45849113190     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.08304     Document Type: Article
Times cited : (88)

References (50)
  • 1
    • 0031803734 scopus 로고    scopus 로고
    • Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome
    • Scheurlen WG, Schwabe GC, Joos S, Mollenhauer J, Sorensen N, and Kuhl J (1998). Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome. J Clin Oncol 16, 2478-2485.
    • (1998) J Clin Oncol , vol.16 , pp. 2478-2485
    • Scheurlen, W.G.1    Schwabe, G.C.2    Joos, S.3    Mollenhauer, J.4    Sorensen, N.5    Kuhl, J.6
  • 2
    • 36149000214 scopus 로고    scopus 로고
    • Medulloblastoma in childhood: New biological advances
    • Crawford JR, MacDonald TJ, and Packer RJ (2007). Medulloblastoma in childhood: new biological advances. Lancet Neurol 6, 1073-1085.
    • (2007) Lancet Neurol , vol.6 , pp. 1073-1085
    • Crawford, J.R.1    MacDonald, T.J.2    Packer, R.J.3
  • 3
    • 0038748216 scopus 로고    scopus 로고
    • Fatal toxicity following radio- and chemotherapy of medulloblastoma in a child with unrecognized Nijmegen breakage syndrome
    • Distel L, Neubauer S, Varon R, Holter W, and Grabenbauer G (2003). Fatal toxicity following radio- and chemotherapy of medulloblastoma in a child with unrecognized Nijmegen breakage syndrome. Med Pediatr Oncol 41, 44-48.
    • (2003) Med Pediatr Oncol , vol.41 , pp. 44-48
    • Distel, L.1    Neubauer, S.2    Varon, R.3    Holter, W.4    Grabenbauer, G.5
  • 4
    • 0036170178 scopus 로고    scopus 로고
    • The daily oral administration of high doses of transresveratrol to rats for 28 days is not harmful
    • Juan ME, Vinardell MP, and Planas JM (2002). The daily oral administration of high doses of transresveratrol to rats for 28 days is not harmful. J Nutr 132, 257-260.
    • (2002) J Nutr , vol.132 , pp. 257-260
    • Juan, M.E.1    Vinardell, M.P.2    Planas, J.M.3
  • 5
    • 33847276576 scopus 로고    scopus 로고
    • Estrogen and resveratrol regulate Rac and Cdc42 signaling to the actin cytoskeleton of metastatic breast cancer cells
    • Azios NG, Krishnamoorthy L, Harris M, Cubano LA, Cammer M, and Dharmawardhane SF (2007). Estrogen and resveratrol regulate Rac and Cdc42 signaling to the actin cytoskeleton of metastatic breast cancer cells. Neoplasia 9, 147-158.
    • (2007) Neoplasia , vol.9 , pp. 147-158
    • Azios, N.G.1    Krishnamoorthy, L.2    Harris, M.3    Cubano, L.A.4    Cammer, M.5    Dharmawardhane, S.F.6
  • 6
    • 0142165219 scopus 로고    scopus 로고
    • Resveratrol promotes differentiation and induces Fas-independent apoptosis of human medulloblastoma cells
    • Wang Q, Li H, Wang XW, Wu DC, Chen XY, and Liu J (2003). Resveratrol promotes differentiation and induces Fas-independent apoptosis of human medulloblastoma cells. Neurosci Lett 351, 83-86.
    • (2003) Neurosci Lett , vol.351 , pp. 83-86
    • Wang, Q.1    Li, H.2    Wang, X.W.3    Wu, D.C.4    Chen, X.Y.5    Liu, J.6
  • 7
    • 33845919326 scopus 로고    scopus 로고
    • The ins and outs of MYC regulation by posttranslational mechanisms
    • Vervoorts J, Lüscher-Firzlaff J, and Lüscher B (2006). The ins and outs of MYC regulation by posttranslational mechanisms. J Biol Chem 281, 34725-34729.
    • (2006) J Biol Chem , vol.281 , pp. 34725-34729
    • Vervoorts, J.1    Lüscher-Firzlaff, J.2    Lüscher, B.3
  • 9
    • 33750358736 scopus 로고    scopus 로고
    • c-Myc downregulation: A critical molecular event in resveratrol-induced cell cycle arrest and apoptosis of human medulloblastoma cells
    • Zhang P, Li H, Wu ML, Chen XY, Kong QY, Wang XW, Sun Y, Wen S, and Liu J (2006). c-Myc downregulation: a critical molecular event in resveratrol-induced cell cycle arrest and apoptosis of human medulloblastoma cells. J Neurooncol 80, 123-131.
    • (2006) J Neurooncol , vol.80 , pp. 123-131
    • Zhang, P.1    Li, H.2    Wu, M.L.3    Chen, X.Y.4    Kong, Q.Y.5    Wang, X.W.6    Sun, Y.7    Wen, S.8    Liu, J.9
  • 12
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • Buettner R, Mora LB, and Jove R (2002). Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 8, 945-954.
    • (2002) Clin Cancer Res , vol.8 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 14
    • 33751575658 scopus 로고    scopus 로고
    • The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis
    • Rosen DG, Mercado-Uribe I, Yang G, Bast RC, Amin HM, Lai R, and Liu J (2006). The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis. Cancer 107, 2730-2740.
    • (2006) Cancer , vol.107 , pp. 2730-2740
    • Rosen, D.G.1    Mercado-Uribe, I.2    Yang, G.3    Bast, R.C.4    Amin, H.M.5    Lai, R.6    Liu, J.7
  • 15
    • 85047699589 scopus 로고    scopus 로고
    • Constitutive activation of Stat3a in brain tumors: Localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2)
    • Schaefer LK, Ren Z, Fuller GN, and Schaefer TS (2002). Constitutive activation of Stat3a in brain tumors: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2). Oncogene 21, 2058-2065.
    • (2002) Oncogene , vol.21 , pp. 2058-2065
    • Schaefer, L.K.1    Ren, Z.2    Fuller, G.N.3    Schaefer, T.S.4
  • 16
    • 31144460828 scopus 로고    scopus 로고
    • Stem-cell protein Piwil2 is widely expressed in tumors and inhibits apoptosis through activation of Stat3/Bcl-XL pathway
    • Lee JH, Schütte D, Wulf G, Füzesi L, Radzun HJ, Schweyer S, Engel W, and Nayernia K (2006). Stem-cell protein Piwil2 is widely expressed in tumors and inhibits apoptosis through activation of Stat3/Bcl-XL pathway. Hum Mol Genet 15, 201-211.
    • (2006) Hum Mol Genet , vol.15 , pp. 201-211
    • Lee, J.H.1    Schütte, D.2    Wulf, G.3    Füzesi, L.4    Radzun, H.J.5    Schweyer, S.6    Engel, W.7    Nayernia, K.8
  • 17
    • 33947197883 scopus 로고    scopus 로고
    • Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells
    • Bhardwai A, Sethi G, Vadhan-Raj S, Bueso-Ramos C, Takada Y, Gaur U, Nair AS, Shishodia S, and Aggarwal BB (2007). Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. Blood 109, 2293-2302.
    • (2007) Blood , vol.109 , pp. 2293-2302
    • Bhardwai, A.1    Sethi, G.2    Vadhan-Raj, S.3    Bueso-Ramos, C.4    Takada, Y.5    Gaur, U.6    Nair, A.S.7    Shishodia, S.8    Aggarwal, B.B.9
  • 19
    • 0032819843 scopus 로고    scopus 로고
    • Expression of leukemia-inhibitory factor as an autocrinal growth factor in human medulloblastomas
    • Liu J, Li JW, Gang Y, Guo L, and Li H (1999). Expression of leukemia-inhibitory factor as an autocrinal growth factor in human medulloblastomas. J Cancer Res Clin Oncol 125, 475-480.
    • (1999) J Cancer Res Clin Oncol , vol.125 , pp. 475-480
    • Liu, J.1    Li, J.W.2    Gang, Y.3    Guo, L.4    Li, H.5
  • 22
    • 0035650930 scopus 로고    scopus 로고
    • Changes in survivin messenger RNA level during cisplatin treatment in gastric cancer
    • Ikeguchi M and Kaibara N (2001). Changes in survivin messenger RNA level during cisplatin treatment in gastric cancer. Int J Mol Med 8, 661-666.
    • (2001) Int J Mol Med , vol.8 , pp. 661-666
    • Ikeguchi, M.1    Kaibara, N.2
  • 23
    • 38049105451 scopus 로고    scopus 로고
    • The novel phospholipase C activator, m-3M3FBS, induces apoptosis in tumor cells through caspase activation, down-regulation of XIAP and intracellular calcium signaling
    • Jung EM, Lee TJ, Park JW, Bae YS, Kim SH, Choi YH, and Kwon TK (2008). The novel phospholipase C activator, m-3M3FBS, induces apoptosis in tumor cells through caspase activation, down-regulation of XIAP and intracellular calcium signaling. Apoptosis 13, 133-145.
    • (2008) Apoptosis , vol.13 , pp. 133-145
    • Jung, E.M.1    Lee, T.J.2    Park, J.W.3    Bae, Y.S.4    Kim, S.H.5    Choi, Y.H.6    Kwon, T.K.7
  • 26
    • 0034852498 scopus 로고    scopus 로고
    • Neurotrophin and neurotrophin receptor expression by cells of the human lamina cribrosa
    • Lambert W, Agarwal R, Howe W, Clark AF, and Wordinger RJ (2001). Neurotrophin and neurotrophin receptor expression by cells of the human lamina cribrosa. Invest Ophthalmol Vis Sci 42, 2315-2323.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 2315-2323
    • Lambert, W.1    Agarwal, R.2    Howe, W.3    Clark, A.F.4    Wordinger, R.J.5
  • 27
    • 0038449825 scopus 로고    scopus 로고
    • Transcriptional profiling of neuronal differentiation by human embryonal carcinoma stem cells in vitro
    • Przyborski SA, Smith S, and Wood A (2003). Transcriptional profiling of neuronal differentiation by human embryonal carcinoma stem cells in vitro. Stem Cells 21, 459-471.
    • (2003) Stem Cells , vol.21 , pp. 459-471
    • Przyborski, S.A.1    Smith, S.2    Wood, A.3
  • 28
    • 36048968158 scopus 로고    scopus 로고
    • Regulation of Cox-2 by cyclic AMP response element binding protein in prostate cancer: Potential role for nexrutine
    • Ghosh R, Garcia GE, Crosby K, Inoue H, Thompson IM, Troyer DA, and Kumar AP (2007). Regulation of Cox-2 by cyclic AMP response element binding protein in prostate cancer: potential role for nexrutine. Neoplasia 9, 893-899.
    • (2007) Neoplasia , vol.9 , pp. 893-899
    • Ghosh, R.1    Garcia, G.E.2    Crosby, K.3    Inoue, H.4    Thompson, I.M.5    Troyer, D.A.6    Kumar, A.P.7
  • 29
    • 12144291647 scopus 로고    scopus 로고
    • Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells
    • Simile MM, De Miglio MR, Muroni MR, Frau M, Asara G, Serra S, Muntoni MD, Seddaiu MA, Daino L, Feo F, et al. (2004). Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells. Carcinogenesis 25, 333-341.
    • (2004) Carcinogenesis , vol.25 , pp. 333-341
    • Simile, M.M.1    De Miglio, M.R.2    Muroni, M.R.3    Frau, M.4    Asara, G.5    Serra, S.6    Muntoni, M.D.7    Seddaiu, M.A.8    Daino, L.9    Feo, F.10
  • 30
    • 0021331372 scopus 로고
    • Attachment of vimentin filaments to desmosomal plaques in human meningiomal cells and arachnoidal tissue
    • Kartenbeck J, Schwechheimer K, Moll R, and Franke WW (1984). Attachment of vimentin filaments to desmosomal plaques in human meningiomal cells and arachnoidal tissue. J Cell Biol 98, 1072-1081.
    • (1984) J Cell Biol , vol.98 , pp. 1072-1081
    • Kartenbeck, J.1    Schwechheimer, K.2    Moll, R.3    Franke, W.W.4
  • 31
    • 33750292431 scopus 로고    scopus 로고
    • Inhibition of STAT3 activity with AG490 decreases the invasion of human pancreatic cancer cells in vitro
    • Huang C, Cao J, Huang KJ, Zhang F, Jiang T, Zhu L, and Qiu ZJ (2006). Inhibition of STAT3 activity with AG490 decreases the invasion of human pancreatic cancer cells in vitro. Cancer Sci 97, 1417-1423.
    • (2006) Cancer Sci , vol.97 , pp. 1417-1423
    • Huang, C.1    Cao, J.2    Huang, K.J.3    Zhang, F.4    Jiang, T.5    Zhu, L.6    Qiu, Z.J.7
  • 32
    • 33749055594 scopus 로고    scopus 로고
    • Molecular cross-talk between the NFkappaB and STAT3 signaling pathways in head and neck squamous cell carcinoma
    • Squarize CH, Castilho RM, Sriuranpong V, Pinto DS Jr, and Gutkind JS (2006). Molecular cross-talk between the NFkappaB and STAT3 signaling pathways in head and neck squamous cell carcinoma. Neoplasia 8, 733-746.
    • (2006) Neoplasia , vol.8 , pp. 733-746
    • Squarize, C.H.1    Castilho, R.M.2    Sriuranpong, V.3    Pinto Jr, D.S.4    Gutkind, J.S.5
  • 33
    • 40149094813 scopus 로고    scopus 로고
    • Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells
    • Xiong H, Zhang ZG, Tian XQ, Sun DF, Liang QC, Zhang YJ, Lu R, Chen YX, and Fang JY (2008). Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells. Neoplasia 10, 287-297.
    • (2008) Neoplasia , vol.10 , pp. 287-297
    • Xiong, H.1    Zhang, Z.G.2    Tian, X.Q.3    Sun, D.F.4    Liang, Q.C.5    Zhang, Y.J.6    Lu, R.7    Chen, Y.X.8    Fang, J.Y.9
  • 35
    • 14544267128 scopus 로고    scopus 로고
    • Stage-dependent fate determination of neural precursor cells in mouse forebrain
    • Hirabayashi Y and Gotoh Y (2005). Stage-dependent fate determination of neural precursor cells in mouse forebrain. Neurosci Res 51, 331-336.
    • (2005) Neurosci Res , vol.51 , pp. 331-336
    • Hirabayashi, Y.1    Gotoh, Y.2
  • 36
    • 20544447159 scopus 로고    scopus 로고
    • STAT3 activation in response to growth factors or cytokines participates in retina precursor proliferation
    • Zhang SS, Liu MG, Kano A, Zhang C, Fu XY, and Barnstable CJ (2005). STAT3 activation in response to growth factors or cytokines participates in retina precursor proliferation. Exp Eye Res 81, 103-115.
    • (2005) Exp Eye Res , vol.81 , pp. 103-115
    • Zhang, S.S.1    Liu, M.G.2    Kano, A.3    Zhang, C.4    Fu, X.Y.5    Barnstable, C.J.6
  • 38
    • 0037028249 scopus 로고    scopus 로고
    • Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells
    • Rahaman SO, Harbor PC, Chernova O, Barnett GH, Vogelbaum MA, and Haque SJ (2002). Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells. Oncogene 21, 8404-8413.
    • (2002) Oncogene , vol.21 , pp. 8404-8413
    • Rahaman, S.O.1    Harbor, P.C.2    Chernova, O.3    Barnett, G.H.4    Vogelbaum, M.A.5    Haque, S.J.6
  • 39
    • 34247281958 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction
    • Tsareva SA, Moriggl R, Corvinus FM, Wiederanders B, Schütz A, Kovacic B, and Friedrich K (2007). Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction. Neoplasia 9, 279-291.
    • (2007) Neoplasia , vol.9 , pp. 279-291
    • Tsareva, S.A.1    Moriggl, R.2    Corvinus, F.M.3    Wiederanders, B.4    Schütz, A.5    Kovacic, B.6    Friedrich, K.7
  • 42
    • 34247218059 scopus 로고    scopus 로고
    • Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio
    • Sakinah SA, Handayani ST, and Hawariah LP (2007). Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio. Cancer Cell Int 7, 4.
    • (2007) Cancer Cell Int , vol.7 , pp. 4
    • Sakinah, S.A.1    Handayani, S.T.2    Hawariah, L.P.3
  • 46
    • 34249904410 scopus 로고    scopus 로고
    • Exploitation of drug-induced Bcl-2 overexpression for restoring normal apoptosis function: A promising new approach to the treatment of multidrug resistant cancer
    • Su Y, Zhang X, and Sinko PJ (2007). Exploitation of drug-induced Bcl-2 overexpression for restoring normal apoptosis function: a promising new approach to the treatment of multidrug resistant cancer. Cancer Lett 253, 115-123.
    • (2007) Cancer Lett , vol.253 , pp. 115-123
    • Su, Y.1    Zhang, X.2    Sinko, P.J.3
  • 47
    • 34548522918 scopus 로고    scopus 로고
    • Inhibition of cell growth and induction of apoptosis via inactivation of NF-kappaB by a sulfur compound isolated from garlic in human colon cancer cells
    • Ban JO, Yuk DY, Woo KS, Kim TM, Lee US, Jeong HS, Kim DJ, Chung YB, Hwang BY, Oh KW, et al. (2007). Inhibition of cell growth and induction of apoptosis via inactivation of NF-kappaB by a sulfur compound isolated from garlic in human colon cancer cells. J Pharmacol Sci 104, 374-383.
    • (2007) J Pharmacol Sci , vol.104 , pp. 374-383
    • Ban, J.O.1    Yuk, D.Y.2    Woo, K.S.3    Kim, T.M.4    Lee, U.S.5    Jeong, H.S.6    Kim, D.J.7    Chung, Y.B.8    Hwang, B.Y.9    Oh, K.W.10
  • 49
    • 42949120754 scopus 로고    scopus 로고
    • Identification of novel direct STAT3 target genes for control of growth and differentiation
    • Snyder M, Huang XY, and Zhang JJ (2008). Identification of novel direct STAT3 target genes for control of growth and differentiation. J Biol Chem 283, 3791-3798.
    • (2008) J Biol Chem , vol.283 , pp. 3791-3798
    • Snyder, M.1    Huang, X.Y.2    Zhang, J.J.3
  • 50
    • 0037173106 scopus 로고    scopus 로고
    • Leukemia inhibitory factor inhibits neuronal terminal differentiation through STAT3 activation
    • Moon C, Yoo JY, Matarazzo V, Sung YK, Kim EJ, and Ronnett GV (2002). Leukemia inhibitory factor inhibits neuronal terminal differentiation through STAT3 activation. Proc Natl Acad Sci USA 99, 9015-9020.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 9015-9020
    • Moon, C.1    Yoo, J.Y.2    Matarazzo, V.3    Sung, Y.K.4    Kim, E.J.5    Ronnett, G.V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.