Differential gene expression and a functional analysis of PCB-exposed children: Understanding disease and disorder development

Environment International

Volumn 40, Issue 1, 2012, Pages 143-154

  Dutta, Sisir K ^a   Mitra, Partha S ^a   Ghosh, Somiranjan ^a   Zang, Shizhu ^a   Sonneborn, Dean ^b   Hertz Picciotto, Irva ^b   Trnovec, Tomas ^c   Palkovicova, Lubica ^c   Sovcikova, Eva ^c   Ghimbovschi, Svetlana ^d   Hoffman, Eric P ^d  

^a HOWARD UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SLOVAK MEDICAL UNIVERSITY   (Slovakia)

^d CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

Environmental exposure; Functional analysis; Gene expression; Microarray; PCB; PCB exposed population

Indexed keywords

BLOOD; CELLS; DISEASES; FUNCTIONAL ANALYSIS; INTERFERONS; METABOLISM; MICROARRAYS; ORGANIC POLLUTANTS; POLYCHLORINATED BIPHENYLS; RNA;

AFFYMETRIX; CARDIO-VASCULAR DISEASE; CARDIOTOXICITY; CELL SIGNALING; CELL-TO-CELL SIGNALING; CELLULAR FUNCTION; DIFFERENTIAL GENE EXPRESSIONS; DIFFERENTIALLY EXPRESSED GENE; DISEASE PROCESS; ENVIRONMENTAL EXPOSURE; EPIDEMIOLOGICAL STUDIES; GENE-ENVIRONMENT INTERACTION; GENECHIPS; GENOTYPING; HEPATOTOXICITY; HUMAN GENOMES; INDIVIDUAL RISKS; MEAN AGES; MOLECULAR MECHANISM; MOLECULAR TRANSPORT; NEPHROTOXICITY; P-VALUES; PATHOPHYSIOLOGY; PATHWAY ANALYSIS; PCB CONCENTRATION; PCB-EXPOSED POPULATION; PERIPHERAL BLOOD MONONUCLEAR CELLS; SERUM LIPID; SLOVAK REPUBLIC;

GENE EXPRESSION;

ARYLDIALKYLPHOSPHATASE 1; BETA1 INTEGRIN; LIPID; POLYCHLORINATED BIPHENYL; PROTEIN BCL 2; RNA;

BIOACCUMULATION; CHILD HEALTH; COHORT ANALYSIS; GENE EXPRESSION; GENETIC ANALYSIS; LIPID; PATHOLOGY; PCB; PHYSIOLOGY; POLLUTION EXPOSURE; RISK FACTOR; TOXICITY;

ARTICLE; BLOOD LEVEL; CARDIOTOXICITY; CARDIOVASCULAR DISEASE; CAUCASIAN; CELL FUNCTION; CELL INTERACTION; CELL MOTION; CELL TRANSPORT; CHILD; COHORT ANALYSIS; ENVIRONMENTAL EXPOSURE; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC ANALYSIS; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; ITGB1 GENE; LIPID BLOOD LEVEL; LIVER TOXICITY; MALIGNANT NEOPLASTIC DISEASE; MICROARRAY ANALYSIS; MINERAL METABOLISM; MOLECULAR MECHANICS; NEPHROTOXICITY; PATHOPHYSIOLOGY; PERIPHERAL BLOOD MONONUCLEAR CELL; PON1 GENE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTO ONCOGENE; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; VITAMIN METABOLISM;

SLOVAKIA;

EID: 84856229233     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2011.07.008     Document Type: Article

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