Congener-specific polychlorinated biphenyl-induced cell death in human kidney cells in vitro: Potential role of caspase

International Journal of Toxicology

Volumn 25, Issue 5, 2006, Pages 341-347

  Chen, Y Q ^a   De, S ^a   Ghosh, S ^a   Dutta, S K ^a  

^a HOWARD UNIVERSITY   (United States)

Author keywords

Apoptosis; Caspase; Human Proximal Tubule Cell Culture; PCB 153; PCB 77

Indexed keywords

CASPASE 3; CASPASE INHIBITOR; DNA FRAGMENT; POLYCHLORINATED BIPHENYL;

AGAR GEL ELECTROPHORESIS; APOPTOSIS; ARTICLE; CELL VIABILITY; CHROMATIN STRUCTURE; CONTROLLED STUDY; DRUG INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY CELL; KIDNEY PROXIMAL TUBULE; LC 50; NEPHROTOXICITY; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; STAINING; WESTERN BLOTTING;

AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; CASPASE 3; CELL LINE; DNA FRAGMENTATION; HUMANS; KIDNEY; LETHAL DOSE 50; POLYCHLORINATED BIPHENYLS;

EID: 33748653806     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1080/10915810600840859     Document Type: Article

References (24)

1. Broker, L. E., F. A. Kruyt, and G. Giaccone. 2005. Cell death independent of caspases: A review. Clin. Cancer Res. 11:31-55.
2. Cande, C., F. Cecconi, P. Dessen, and G. Kroemer. 2002. Apoptosis-inducing factor (AIF): Key to the conserved caspase-independent pathways of cell death? J. Cell Sci. 115:4727-4734.
3. Chen, G., and N. J. Bunce. 2004. Interaction between halogenated aromatic compounds in the Ah receptor signal transduction pathway. Environ Toxicol. 19:480-489.
4. Chen, Y. Q., S. De, L. Moses, E. Hoffman, S. Ghosh, and S. K. Dutta. 2005. Polychlorinated biphenyls (PCBs) induced gene expression profiling in human kidney cells. In Proceedings of the 105th ASM General Meeting, Atlanta, Georgia, 427.
5. Chu, I., D. C. Villeneuve, A. Yagminas, P. Lecavalier, H. Hakansson, U. G. Ahlborg, V. E. Valli, S. W. Kennedy, A. Bergman, R. F. Seegal, et al. 1995. Toxicity of PCB 77 (3,3′,4,4′-tetrachlorobiphenyl) and PCB 118 (2,3′,4,4′5-pentachlorobiphenyl) in the rat following subchronic dietary exposure. Fundam. Appl. Toxicol. 26:282-292.
6. Cowburn, A. S., J. F. White, J. Deighton, S. R. Walmsley, and E. R. Chilvers. 2005. z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species. Blood 105:2970-2972.
7. Duttaroy, A., D. Bourbeau, X. L. Wang, and E. Wang. 1998. Apoptosis rate can be accelerated or decelerated by overexpression or reduction of the level of elongation factor-1 alpha. Exp. Cell Res. 238:168-176.
8. Filipovic, D. M., X. Meng, and W. B. Reeves. 1999. Inhibition of PARP prevents oxidant-induced necrosis but not apoptosis in LLC-PK1 cells. Am. J. Physiol. 277:F428-F436.
9. Freshney, R. 2005. Culture of animal cells: A manual of basic technique. New York: Wiley-Liss.
10. Gafni, J., P. W. Wong, and I. N. Pessah. 2004. Non-coplanar 2,2′,3,5′,6-pentachlorobiphenyl (PCB 95) amplifies ionotropic glutamate receptor signaling in embryonic cerebellar granule neurons by a mechanism involving ryanodine receptors. Toxicol. Sci. 77:72-82.
11. Howard, A. S., R. Fitzpatrick, I. Pessah, P. Kostyniak, and P. J. Lein. 2003. Polychlorinated biphenyls induce caspase-dependent cell death in cultured embryonic rat hippocampal but not cortical neurons via activation of the ryanodine receptor. Toxicol. Appl. Pharmacol. 190:72-86.
12. Jaattela, M. 2004. Multiple cell death pathways as regulators of tumor initiation and progression. Oncogene 23:2746-2756.
13. Joza, N., S. A. Susin, E. Daugas, W. L. Stanford, S. K. Cho, C. Y. Li, T. Sasaki, A. J. Elia, H. Y. Cheng, L. Ravagnan, K. F. Ferri, N. Zamzami, A. Wakeham, R. Hakem, H. Yoshida, Y. Y. Kong, T. W. Mak, J. C. Zuniga-Pflucker, G. Kroemer, and J. M. Penninger. 2001. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 410:549-554.
14. Li, P., D. Nijhawan, I. Budihardjo, S. M. Srinivasula, M. Ahmad, E. S. Alnemri, and X. Wang. 1997. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91:479-489.
15. Machala, M., L. Blaha, J. Vondracek, J. E. Trosko, J. Scott, and B. L. Upham. 2003. Inhibition of gap junctional intercellular communication by noncoplanar polychlorinated biphenyls: Inhibitory potencies and screening for potential mode(s) of action. Toxicol. Sci. 76:102-111.
16. Patterson, D. G., Jr., G. D. Todd, W. E. Turner, V. Maggio, L. R. Alexander, and L. L. Needham. 1994. Levels of non-ortho-substituted (coplanar), mono-and di-ortho-substituted polychlorinated biphenyls, dibenzo-p-dioxins, and dibenzofurans in human serum and adipose tissue. Environ. Health. Perspect. 102:195-204.
17. Prabhakaran, K., L. Li, J. L. Borowitz, and G. E. Isom. 2004. Caspase inhibition switches the mode of cell death induced by cyanide by enhancing reactive oxygen species generation and PARP-1 activation. Toxicol. Appl. Pharmacol. 195:194-202.
18. Ryan, M. J., G. Johnson, J. Kirk, S. M. Fuerstenberg, R. A. Zager, and B. Torok-Storb. 1994. HK-2: An immortalized proximal tubule epithelial cell line from normal adult human kidney. Kidney Int. 45:48-57.
19. Sambrook, J., and D. W. Russell. 2001. Molecular cloning: Laboratory manual. 3d ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
20. Sanchez-Alonso, J. A., P. Lopez-Aparicio, M. N. Recio, and M. A. Perez-Albarsanz. 2003. Apoptosis-mediated neurotoxic potential of a planar (PCB 77) and a nonplanar (PCB 153) polychlorinated biphenyl congeners in neuronal cell cultures. Toxicol. Lett. 144:337-349.
21. Schulze-Osthoff, K., A. C. Bakker, B. Vanhaesebroeck, R. Beyaert, W. A. Jacob, and W. Fiers. 1992. Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions: Evidence for the involvement of mitochondrial radical generation. J. Biol. Chem. 267:5317-5323.
22. Shalat, S. L., L. D. True, L. E. Fleming, and P. E. Pace. 1989. Kidney cancer in utility workers exposed to polychlorinated biphenyls (PCBs). Br. J. Ind. Med. 46:823-824.
23. Thonel, A. D., and J. E. Eriksson. 2005. Regulation of death receptors: Relevance in cancer therapies. Toxicol. Appl. Pharmacol. 207:123-132.
24. Zhao, M., F. Antunes, J. W. Eaton, and U. T. Brunk. 2003. Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis. Eur. J. Biochem. 270:3778-3786.