Nerve excitability changes related to axonal degeneration in amyotrophic lateral sclerosis: Insights from the transgenic SOD1 G127X mouse model

Experimental Neurology

Volumn 233, Issue 1, 2012, Pages 408-420

  Moldovan, Mihai ^a,c   Alvarez, Susana ^a,c   Pinchenko, Volodymyr ^a   Marklund, Stefan ^b   Graffmo, Karin S ^b   Krarup, Christian ^a,c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UMEÅ UNIVERSITY   (Sweden)

^c International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

Author keywords

Excitability; Internode; Ion channels; Motor neuron disease; Mouse model; Nerve activity; Node of Ranvier; Regeneration

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPOUND MOTOR ACTION POTENTIAL; CONTROLLED STUDY; DISEASE CLASSIFICATION; EVOKED MUSCLE RESPONSE; F WAVE; HUMAN; HYPERPOLARIZATION; MATHEMATICAL PARAMETERS; MEMBRANE DEPOLARIZATION; MOTONEURON; MOTOR PERFORMANCE; MOTOR UNIT POTENTIAL; MOUSE; MUSCLE STRENGTH; MUTANT; NERVE CONDUCTION; NERVE DEGENERATION; NERVE EXCITABILITY; NERVE FIBER DEGENERATION; NERVE FIBER MEMBRANE CONDUCTANCE; NERVOUS SYSTEM PARAMETERS; NEUROLOGIC EXAMINATION; NONHUMAN; PRIORITY JOURNAL; REFRACTORY PERIOD; STIMULUS RESPONSE SLOPE; THRESHOLD TRACKING; TIBIAL NERVE; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; AXONS; DIFFERENTIAL THRESHOLD; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; GLYCINE; HUMANS; MICE; MICE, TRANSGENIC; MOTOR NEURONS; MOVEMENT; NEURAL CONDUCTION; REACTION TIME; SUPEROXIDE DISMUTASE; TIBIAL NERVE; TIME FACTORS;

EID: 84856222650     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2011.11.008     Document Type: Article

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