Mitochondrial antioxidants alleviate oxidative and nitrosative stress in a cellular model of sepsis

Pharmaceutical Research

Volumn 28, Issue 11, 2011, Pages 2910-2919

  Apostolova, Nadezda ^a,b   Garcia Bou, Remedios ^c   Hernandez Mijares, Antonio ^a,c   Herance, Raul ^d   Rocha, Milagros ^a,b,c   Victor, Victor M ^a,b,c  

^a UNIVERSITY OF VALENCIA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL UNIVERSITARIO DR PESET   (Spain)

^d Barcelona Biomedical Research Park   (Spain)

Author keywords

Hypoxia; Mitochondria; Mitoquinone; Reactive oxygen species; Sepsis

Indexed keywords

ANTIOXIDANT; GLUTATHIONE ETHYL ESTER; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MITOQUINONE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); TYROSINE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL ACTIVATION; CELL HYPOXIA; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; NITRATION; NITROSATIVE STRESS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPSIS; UMBILICAL VEIN ENDOTHELIAL CELL;

ANTIOXIDANTS; ENDOTOXINS; ENZYME INHIBITORS; ESCHERICHIA COLI; GLUTATHIONE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MITOCHONDRIA; MODELS, BIOLOGICAL; MOLECULAR TARGETED THERAPY; NAD; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITROSATION; OXIDATIVE STRESS; OXYGEN; PEROXYNITROUS ACID; REACTIVE OXYGEN SPECIES; SEPSIS;

EID: 84856216100     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0528-0     Document Type: Article

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