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Volumn 22, Issue 23, 2011, Pages 1985-1993

Screening on the use of Kluyveromyces marxianus CBS 6556 growing cells as enantioselective biocatalysts for ketone reductions

Author keywords

[No Author keywords available]

Indexed keywords

2 TETRALONE; ACETONE; ALCOHOL; ALKYL ARYL KETONE; HETEROCYCLIC KETONE; ISOMERASE; KETONE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 84856093119     PISSN: 09574166     EISSN: 1362511X     Source Type: Journal    
DOI: 10.1016/j.tetasy.2011.11.014     Document Type: Article
Times cited : (30)

References (69)
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    • The absolute configuration of the stereogenic center of the isolated product was assigned by comparison with the specific rotation value reported in the literature
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    • (2008) Tetrahedron: Asymmetry , vol.19 , pp. 237-246
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  • 21
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    • Absolute ethanol was used as the solvent for the substrate solubilization, due to the yeast tolerance to ethanol, and also because of the noteworthy yeast regeneration of the cofactor NAD(P)H through the ethyl alcohol oxidation into acetone
    • Absolute ethanol was used as the solvent for the substrate solubilization, due to the yeast tolerance to ethanol, and also because of the noteworthy yeast regeneration of the cofactor NAD(P)H through the ethyl alcohol oxidation into acetone; T. Kometani, H. Yoshii, and R. Matsuno J. Mol. CataL. B- Enzym. 1 1996 45 52
    • (1996) J. Mol. CataL. B- Enzym. , vol.1 , pp. 45-52
    • Kometani, T.1    Yoshii, H.2    Matsuno, R.3
  • 24
    • 0030575815 scopus 로고    scopus 로고
    • The configuration of the stereogenic center of the isolated product was assigned by comparison with the specific rotation value in two reference solvents (chloroform and ethanol)
    • The configuration of the stereogenic center of the isolated product was assigned by comparison with the specific rotation value in two reference solvents (chloroform and ethanol): B.H. Hoff, V. Waagen, and T. Anthonsen Tetrahedron: Asymmetry 7 1996 3181 3186
    • (1996) Tetrahedron: Asymmetry , vol.7 , pp. 3181-3186
    • Hoff, B.H.1    Waagen, V.2    Anthonsen, T.3
  • 41
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    • 3I; after work-up, the ketone was isolated by silica gel column chromatography (petroleum ether/ethyl acetate = 96:4). For enantiomeric excess measurements, the racemic acetates of alcohol 2o were prepared
    • 3I; after work-up, the ketone was isolated by silica gel column chromatography (petroleum ether/ethyl acetate = 96:4). For enantiomeric excess measurements, the racemic acetates of alcohol 2o were prepared: N.S. Hatzakis, and I. Smonou Tetrahedron Lett. 45 2004 2755 2757
    • (2004) Tetrahedron Lett. , vol.45 , pp. 2755-2757
    • Hatzakis, N.S.1    Smonou, I.2
  • 56
    • 42349106782 scopus 로고    scopus 로고
    • A usual limitation of asymmetric synthesis with whole growing cells is often the formation of complex mixtures of products. In this screening, the purification of the products was not easy in some cases, due to the presence of 2-phenylethanol, formed as a by-product from the metabolism of many yeasts, including Kluyveromyces marxianus
    • A usual limitation of asymmetric synthesis with whole growing cells is often the formation of complex mixtures of products. In this screening, the purification of the products was not easy in some cases, due to the presence of 2-phenylethanol, formed as a by-product from the metabolism of many yeasts, including Kluyveromyces marxianus: L.A. Hazelwood, J.M. Daran, A.J. van Maris, J.T. Pronk, and J.R. Dickinson Appl. Environ. Microbiol. 74 2008 2259 2266
    • (2008) Appl. Environ. Microbiol. , vol.74 , pp. 2259-2266
    • Hazelwood, L.A.1    Daran, J.M.2    Van Maris, A.J.3    Pronk, J.T.4    Dickinson, J.R.5
  • 67
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    • CAS [7779-78-4]; SDBSWeb: (National Institute of Advanced Industrial Science and Technology, date of access: 27-07-2011)
    • 4-Methyl-1-phenylpentan-2-ol. CAS [7779-78-4]; SDBSWeb: http://riodb01.ibase.aist.go.jp/sdbs/ (National Institute of Advanced Industrial Science and Technology, date of access: 27-07-2011).
    • 4-Methyl-1-phenylpentan-2-ol


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.