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Note
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Reactions were conducted in resealable J. Young tubes and heated to 50 °C in an oil bath. Due to the small reation scale, 20 mol % of NaO t -Bu was required to allow the solid to be weighed out accurately. Reactions on larger scale utilize 5 mol % of NaO t -Bu.
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77951800932
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Diastereomeric ratios determined by GC analysis. See the Supporting Information for details on establishing the relative stereochemistry
-
Diastereomeric ratios determined by GC analysis. See the Supporting Information for details on establishing the relative stereochemistry.
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36
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77951780360
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Typical diastereoselectivities of hydride additions to 14 range from 1.5:1 to 6:1 except in the case of l -Selectride (>99:1 dr)
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Typical diastereoselectivities of hydride additions to 14 range from 1.5:1 to 6:1 except in the case of l -Selectride (>99:1 dr).
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