Selegiline and desmethylselegiline stimulate NGF, BDNF, and GDNF synthesis in cultured mouse astrocytes

Biochemical and Biophysical Research Communications

Volumn 279, Issue 3, 2000, Pages 751-755

  Mizuta, Ikuko ^a,c   Ohta, Mitsuhiro ^a,b   Ohta, Kiyoe ^a   Nishimura, Masataka ^a   Mizuta, Eiji ^a   Hayashi, Kyozo ^d   Kuno, Sadako ^a  

^a UTANO NATIONAL HOSPITAL   (Japan)

^b KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^c Japan Foundation for Aging and Health   (Japan)

^d GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Astrocytes; BDNF; Desmethylselegiline; GDNF; Monoamine oxidase (MAO); Neuroprotection; NGF; Parkinson's disease; Selegiline

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); BRAIN DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; NERVE GROWTH FACTOR; NORSELEGILINE; SELEGILINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; MOUSE; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN SYNTHESIS; RECEPTOR UPREGULATION;

GYMNOMYZA SAMOENSIS;

EID: 0034731367     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.4037     Document Type: Article

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