메뉴 건너뛰기




Volumn 119, Issue 3, 2012, Pages 727-735

Expansion of functionally defined mouse hematopoietic stem and progenitor cells by a short isoform of RUNX1/AML1

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; SHORT HAIRPIN RNA; STAT1 PROTEIN; TRANSCRIPTION FACTOR HOXA9; TRANSCRIPTION FACTOR RUNX1;

EID: 84856075673     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-06-362277     Document Type: Article
Times cited : (29)

References (46)
  • 1
    • 47149088471 scopus 로고    scopus 로고
    • Cytokines regulating hematopoietic stem cell function
    • Zhang CC, Lodish HF. Cytokines regulating hematopoietic stem cell function. Curr Opin Hematol. 2008;15(4):307-311.
    • (2008) Curr Opin Hematol , vol.15 , Issue.4 , pp. 307-311
    • Zhang, C.C.1    Lodish, H.F.2
  • 2
    • 38349121930 scopus 로고    scopus 로고
    • Signaling pathways governing stem-cell fate
    • Blank U, Karlsson G, Karlsson S. Signaling pathways governing stem-cell fate. Blood. 2008;111(2):492-503.
    • (2008) Blood , vol.111 , Issue.2 , pp. 492-503
    • Blank, U.1    Karlsson, G.2    Karlsson, S.3
  • 3
    • 0037023528 scopus 로고    scopus 로고
    • HOXB4-induced expansion of adult hematopoietic stem cells ex vivo
    • Antonchuk J, Sauvageau G, Humphries RK. HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell. 2002;109(1):39-45.
    • (2002) Cell , vol.109 , Issue.1 , pp. 39-45
    • Antonchuk, J.1    Sauvageau, G.2    Humphries, R.K.3
  • 5
    • 64249099616 scopus 로고    scopus 로고
    • A functional screen to identify novel effectors of hematopoietic stem cell activity
    • Deneault E, Cellot S, Faubert A, et al. A functional screen to identify novel effectors of hematopoietic stem cell activity. Cell. 2009;137(2):369-379.
    • (2009) Cell , vol.137 , Issue.2 , pp. 369-379
    • Deneault, E.1    Cellot, S.2    Faubert, A.3
  • 6
    • 2942659322 scopus 로고    scopus 로고
    • Oncogenic potential of the RUNX gene family: 'Overview'
    • DOI 10.1038/sj.onc.1207755
    • Ito Y. Oncogenic potential of the RUNX gene family: 'overview'. Oncogene. 2004;23(24):4198-4208. (Pubitemid 38765135)
    • (2004) Oncogene , vol.23 , Issue.24 , pp. 4198-4208
    • Ito, Y.1
  • 7
    • 0036636857 scopus 로고    scopus 로고
    • Core-binding factors in haematopoiesis and leukaemia
    • Speck NA, Gilliland DG. Core-binding factors in haematopoiesis and leukaemia. Nat Rev Cancer. 2002;2(7):502-513. (Pubitemid 37328932)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.7 , pp. 502-513
    • Speck, N.A.1    Gilliland, D.G.2
  • 8
    • 38349179230 scopus 로고    scopus 로고
    • Of lineage and legacy: The development of mammalian hematopoietic stem cells
    • Dzierzak E, Speck NA. Of lineage and legacy: the development of mammalian hematopoietic stem cells. Nat Immunol. 2008;9(2):129-136.
    • (2008) Nat Immunol , vol.9 , Issue.2 , pp. 129-136
    • Dzierzak, E.1    Speck, N.A.2
  • 11
    • 44449104279 scopus 로고    scopus 로고
    • AML1/ Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis
    • Ichikawa M, Goyama S, Asai T, et al. AML1/ Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis. J Immunol. 2008;180(7):4402-4408.
    • (2008) J Immunol , vol.180 , Issue.7 , pp. 4402-4408
    • Ichikawa, M.1    Goyama, S.2    Asai, T.3
  • 12
    • 34249694973 scopus 로고    scopus 로고
    • Isoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1
    • Tsuzuki S, Hong D, Gupta R, et al. Isoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1. PLoS Med. 2007;4(5):e172.
    • (2007) PLoS Med , vol.4 , Issue.5
    • Tsuzuki, S.1    Hong, D.2    Gupta, R.3
  • 13
    • 79953833432 scopus 로고    scopus 로고
    • Promotion and maintenance of leukemia by ERG
    • Tsuzuki S, Taguchi O, Seto M. Promotion and maintenance of leukemia by ERG. Blood. 2011;117(14):3858-3868.
    • (2011) Blood , vol.117 , Issue.14 , pp. 3858-3868
    • Tsuzuki, S.1    Taguchi, O.2    Seto, M.3
  • 15
    • 0035863391 scopus 로고    scopus 로고
    • Synthetic protein transduction domains: Enhanced transduction potential in vitro and in vivo
    • Ho A, Schwarze SR, Mermelstein SJ, et al. Synthetic protein transduction domains: enhanced transduction potential in vitro and in vivo. Cancer Res. 2001;61(2):474-477. (Pubitemid 32128600)
    • (2001) Cancer Research , vol.61 , Issue.2 , pp. 474-477
    • Ho, A.1    Schwarze, S.R.2    Mermelstein, S.J.3    Waksman, G.4    Dowdy, S.F.5
  • 16
    • 33746167484 scopus 로고    scopus 로고
    • + hematopoietic cells
    • DOI 10.1158/0008-5472.CAN-06-0458
    • Takeda A, Goolsby C, Yaseen NR. NUP98- HOXA9 induces long-term proliferation and blocks differentiation of primary human CD34+ hematopoietic cells. Cancer Res. 2006;66(13):6628-6637. (Pubitemid 44085619)
    • (2006) Cancer Research , vol.66 , Issue.13 , pp. 6628-6637
    • Takeda, A.1    Goolsby, C.2    Yaseen, N.R.3
  • 18
    • 0036090290 scopus 로고    scopus 로고
    • Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion
    • Thorsteinsdottir U, Mamo A, Kroon E, et al. Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion. Blood. 2002;99(1):121-129.
    • (2002) Blood , vol.99 , Issue.1 , pp. 121-129
    • Thorsteinsdottir, U.1    Mamo, A.2    Kroon, E.3
  • 20
    • 3242669145 scopus 로고    scopus 로고
    • Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
    • DOI 10.1016/j.cell.2004.07.004, PII S0092867404006622
    • Arai F, Hirao A, Ohmura M, et al. Tie2/angiopoietin- 1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell. 2004;118(2):149-161. (Pubitemid 38962572)
    • (2004) Cell , vol.118 , Issue.2 , pp. 149-161
    • Arai, F.1    Hirao, A.2    Ohmura, M.3    Sato, H.4    Matsuoka, S.5    Takubo, K.6    Ito, K.7    Koh, G.Y.8    Suda, T.9
  • 21
    • 55449106913 scopus 로고    scopus 로고
    • Differential expression of novel potential regulators in hematopoietic stem cells
    • Forsberg EC, Prohaska SS, Katzman S, et al. Differential expression of novel potential regulators in hematopoietic stem cells. PLoS Genet. 2005;1(3):e28.
    • (2005) PLoS Genet , vol.1 , Issue.3
    • Forsberg, E.C.1    Prohaska, S.S.2    Katzman, S.3
  • 22
    • 40749092795 scopus 로고    scopus 로고
    • Candidate genes for expansion and transformation of hematopoietic stem cells by NUP98-HOX fusion genes
    • Palmqvist L, Pineault N, Wasslavik C, et al. Candidate genes for expansion and transformation of hematopoietic stem cells by NUP98-HOX fusion genes. PLoS One. 2007;2(1):e768.
    • (2007) PLoS One , vol.2 , Issue.1
    • Palmqvist, L.1    Pineault, N.2    Wasslavik, C.3
  • 23
    • 48149095026 scopus 로고    scopus 로고
    • Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells
    • Goyama S, Yamamoto G, Shimabe M, et al. Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells. Cell Stem Cell. 2008;3(2):207-220.
    • (2008) Cell Stem Cell , vol.3 , Issue.2 , pp. 207-220
    • Goyama, S.1    Yamamoto, G.2    Shimabe, M.3
  • 24
    • 66149115277 scopus 로고    scopus 로고
    • IFNalpha activates dormant haematopoietic stem cells in vivo
    • Essers MAG, Offner S, Blanco-Bose WE, et al. IFNalpha activates dormant haematopoietic stem cells in vivo. Nature. 2009;458(7240):904-908.
    • (2009) Nature , vol.458 , Issue.7240 , pp. 904-908
    • Essers, M.A.G.1    Offner, S.2    Blanco-Bose, W.E.3
  • 25
    • 67149091317 scopus 로고    scopus 로고
    • Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon dependent exhaustion
    • Sato T, Onai N, Yoshihara H, et al. Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon dependent exhaustion. Nat Med. 2009;15(5):696-700.
    • (2009) Nat Med , vol.15 , Issue.5 , pp. 696-700
    • Sato, T.1    Onai, N.2    Yoshihara, H.3
  • 26
    • 0037130961 scopus 로고    scopus 로고
    • A stem cell molecular signature
    • Ivanova NB, Dimos JT, Schaniel C, et al. A stem cell molecular signature. Science. 2002;298(5593):601-604.
    • (2002) Science , vol.298 , Issue.5593 , pp. 601-604
    • Ivanova, N.B.1    Dimos, J.T.2    Schaniel, C.3
  • 29
    • 33748850636 scopus 로고    scopus 로고
    • Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
    • DOI 10.1038/ni1381, PII NI1381
    • Kirstetter P, Anderson K, Porse BT, et al. Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat Immunol. 2006;7(10):1048-1056. (Pubitemid 44420649)
    • (2006) Nature Immunology , vol.7 , Issue.10 , pp. 1048-1056
    • Kirstetter, P.1    Anderson, K.2    Porse, B.T.3    Jacobsen, S.E.W.4    Nerlov, C.5
  • 33
    • 66049102512 scopus 로고    scopus 로고
    • Hedgehog signaling is dispensable for adult hematopoietic stem cell function
    • Gao J, Graves S, Koch U, et al. Hedgehog signaling is dispensable for adult hematopoietic stem cell function. Cell Stem Cell. 2009;4(6):548-558.
    • (2009) Cell Stem Cell , vol.4 , Issue.6 , pp. 548-558
    • Gao, J.1    Graves, S.2    Koch, U.3
  • 34
    • 33750566665 scopus 로고    scopus 로고
    • Notch signaling in stem cell systems
    • DOI 10.1634/stemcells.2005-0661
    • Chiba S. Concise review: Notch signaling in stem cell systems. Stem Cells. 2006;24(11):2437-2447. (Pubitemid 44674304)
    • (2006) Stem Cells , vol.24 , Issue.11 , pp. 2437-2447
    • Chiba, S.1
  • 36
    • 0037396675 scopus 로고    scopus 로고
    • The competitive nature of HOXB4-transduced HSC is limited by PBX1: The generation of ultra-competitive stem cells retaining full differentiation potential
    • DOI 10.1016/S1074-7613(03)00090-6
    • Krosl J, Beslu N, Mayotte N, et al. The competitive nature of HOXB4-transduced HSC is limited by PBX1 the generation of ultra-competitive stem cells retaining full differentiation potential. Immunity. 2003;18(4):561-571. (Pubitemid 36513637)
    • (2003) Immunity , vol.18 , Issue.4 , pp. 561-571
    • Krosl, J.1    Beslu, N.2    Mayotte, N.3    Humphries, R.K.4    Sauvageau, G.5
  • 37
    • 79951698622 scopus 로고    scopus 로고
    • Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation
    • Takizawa H, Regoes RR, Boddupalli CS, et al. Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation. J Exp Med. 2011;208(2):273-284.
    • (2011) J Exp Med , vol.208 , Issue.2 , pp. 273-284
    • Takizawa, H.1    Regoes, R.R.2    Boddupalli, C.S.3
  • 38
    • 32544445732 scopus 로고    scopus 로고
    • AML1 deletion in adult mice causes splenomegaly and lymphomas
    • DOI 10.1038/sj.onc.1209136, PII 1209136
    • Putz G, Rosner A, Nuesslein I, et al. AML1 deletion in adult mice causes splenomegaly and lymphomas. Oncogene. 2006;25(6):929-939. (Pubitemid 43237711)
    • (2006) Oncogene , vol.25 , Issue.6 , pp. 929-939
    • Putz, G.1    Rosner, A.2    Nuesslein, I.3    Schmitz, N.4    Buchholz, F.5
  • 39
    • 9444264705 scopus 로고    scopus 로고
    • Haploinsufficiency of AML1 results in a decrease in the number of LTR-HSCs while simultaneously inducing an increase in more mature progenitors
    • DOI 10.1182/blood-2003-12-4349
    • Sun W, Downing JR. Haploinsufficiency of AML1 results in a decrease in the number of LTR-HSCs while simultaneously inducing an increase in more mature progenitors. Blood. 2004;104(12):3565-3572. (Pubitemid 39564428)
    • (2004) Blood , vol.104 , Issue.12 , pp. 3565-3572
    • Sun, W.1    Downing, J.R.2
  • 40
    • 0344413639 scopus 로고    scopus 로고
    • In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein
    • DOI 10.1038/nm951
    • Krosl J, Austin P, Beslu N, et al. In vitro expansion of hematopoietic stem cells by recombinant TATHOXB4 protein. Nat Med. 2003;9(11):1428-1432. (Pubitemid 37466195)
    • (2003) Nature Medicine , vol.9 , Issue.11 , pp. 1428-1432
    • Krosl, J.1    Austin, P.2    Beslu, N.3    Kroon, E.4    Humphries, R.K.5    Sauvageau, G.6
  • 41
    • 78650181159 scopus 로고    scopus 로고
    • Ex vivo expansion of human HSCs with Sendai virus vector expressing HoxB4 assessed by sheep in utero transplantation
    • Abe T, Masuda S, Ban H, et al. Ex vivo expansion of human HSCs with Sendai virus vector expressing HoxB4 assessed by sheep in utero transplantation. Exp Hematol. 2011;39(1):47-54.
    • (2011) Exp Hematol , vol.39 , Issue.1 , pp. 47-54
    • Abe, T.1    Masuda, S.2    Ban, H.3
  • 43
    • 77956279712 scopus 로고    scopus 로고
    • Hemgn is a direct transcriptional target of HOXB4 and induces expansion of murine myeloid progenitor cells
    • Jiang J, Yu H, Shou Y, et al. Hemgn is a direct transcriptional target of HOXB4 and induces expansion of murine myeloid progenitor cells. Blood. 2010;116(5):711-749.
    • (2010) Blood , vol.116 , Issue.5 , pp. 711-749
    • Jiang, J.1    Yu, H.2    Shou, Y.3
  • 44
    • 77956269498 scopus 로고    scopus 로고
    • Downstream targets of HOXB4 in a cell line model of primitive hematopoietic progenitor cells
    • Lee HM, Zhang H, Schulz V, et al. Downstream targets of HOXB4 in a cell line model of primitive hematopoietic progenitor cells. Blood. 2010;116(5):720-730.
    • (2010) Blood , vol.116 , Issue.5 , pp. 720-730
    • Lee, H.M.1    Zhang, H.2    Schulz, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.