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Volumn 37, Issue 2, 2012, Pages 350-363

The neuropeptide y (NPY)-ergic system is associated with behavioral resilience to stress exposure in an animal model of post-traumatic stress disorder

Author keywords

animal model; brain derived neurotrophic factor (BDNF); Neuropeptide Y (NPY); NPY Y1 receptor; post traumatic stress disorder (PTSD)

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; N2 DIPHENYLACETYL N (4 UREIDOMETHYLBENZYL)ARGININAMIDE; NEUROPEPTIDE Y; NEUROPEPTIDE Y1 RECEPTOR; PLACEBO;

EID: 84856032928     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2011.230     Document Type: Article
Times cited : (220)

References (80)
  • 2
    • 0035900179 scopus 로고    scopus 로고
    • Induction of functional and morphological expression of neuropeptide Y (NPY) in cortical cultures by brain-derived neurotrophic factor (BDNF): Evidence for a requirement for extracellular-regulated kinase (ERK)-dependent and ERK-independent mechanisms
    • DOI 10.1016/S0006-8993(01)02999-7, PII S0006899301029997
    • Barnea A, Roberts J (2001). Induction of functional and morphological expression of neuropeptide Y (NPY) in cortical cultures by brain-derived neurotrophic factor (BDNF): evidence for a requirement for extracellular- regulated kinase (ERK)-dependent and ERK-independent mechanisms. Brain Res 919: 57-69. (Pubitemid 33016590)
    • (2001) Brain Research , vol.919 , Issue.1 , pp. 57-69
    • Barnea, A.1    Roberts, J.2
  • 3
    • 0033782054 scopus 로고    scopus 로고
    • Neuropeptides and obesity
    • Beck B (2000). Neuropeptides and obesity. Nutrition 16: 916-923.
    • (2000) Nutrition , vol.16 , pp. 916-923
    • Beck, B.1
  • 4
    • 24144483438 scopus 로고    scopus 로고
    • BDNF function in adult synaptic plasticity: The synaptic consolidation hypothesis
    • DOI 10.1016/j.pneurobio.2005.06.003, PII S0301008205000663
    • Bramham C, Messaoudi E (2005). BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis. Prog Neurobiol 76: 99-125. (Pubitemid 41242884)
    • (2005) Progress in Neurobiology , vol.76 , Issue.2 , pp. 99-125
    • Bramham, C.R.1    Messaoudi, E.2
  • 5
    • 0033998014 scopus 로고    scopus 로고
    • Neuropeptide Y blocks anxiogenic-like behavioral action of corticotropin-releasing factor in an operant conflict test and elevated plus maze
    • DOI 10.1016/S0196-9781(99)00169-2, PII S0196978199001692
    • Britton K, Akwa Y, Spina M, Koob G (2000). Neuropeptide Y blocks anxiogenic-like behavioral action of corticotropin-releasing factor in an operant conflict test and elevated plus maze. Peptides 21: 37-44. (Pubitemid 30126040)
    • (2000) Peptides , vol.21 , Issue.1 , pp. 37-44
    • Britton, K.T.1    Akwa, Y.2    Spina, M.G.3    Koob, G.F.4
  • 7
    • 0028922476 scopus 로고
    • Behavioral effects of neuropeptide y receptor agonists in the elevated plus-maze and fear potentiated startle procedures
    • Broqua P, Wettstein J, Rocher M, Gauthier-Martin B, Junien J (1995). Behavioral effects of neuropeptide Y receptor agonists in the elevated plus-maze and fear potentiated startle procedures. Behav Pharmacol 6: 215-222.
    • (1995) Behav Pharmacol , vol.6 , pp. 215-222
    • Broqua, P.1    Wettstein, J.2    Rocher, M.3    Gauthier-Martin, B.4    Junien, J.5
  • 8
    • 0032528934 scopus 로고    scopus 로고
    • Alterations in neuropeptide Y and Y1 receptor mRNA expression in brains from an animal model of depression: Region specific adaptation after fluoxetine treatment
    • DOI 10.1016/S0169-328X(98)00137-5, PII S0169328X98001375
    • Caberlotto L, Fuxe K, Overstreet D, Gerrard P, Hurd Y (1998). Alterations in neuropeptide Y, Y1 receptor mRNA expression in brains from an animal model of depression: Region specific adaptation after fluoxetine treatment. Mol Brain Res 59: 58-65. (Pubitemid 28408447)
    • (1998) Molecular Brain Research , vol.59 , Issue.1 , pp. 58-65
    • Caberlotto, L.1    Fuxe, K.2    Overstreet, D.H.3    Gerrard, P.4    Hurd, Y.L.5
  • 9
    • 0022341166 scopus 로고
    • Neuropeptide Y stimulates feeding but inhibits sexual behavior in rats
    • Clark JT, Kalra PS, Kalra SP (1985). Neuropeptide Y stimulates feeding but inhibits sexual behavior in rats. Endocrinology 117: 2435-2442. (Pubitemid 16194073)
    • (1985) Endocrinology , vol.117 , Issue.6 , pp. 2435-2442
    • Clark, J.T.1    Kalra, P.S.2    Kalra, S.P.3
  • 10
    • 33947700363 scopus 로고    scopus 로고
    • Long-lasting behavioral effects of juvenile trauma in an animal model of PTSD associated with a failure of the autonomic nervous system to recover
    • DOI 10.1016/j.euroneuro.2006.11.003, PII S0924977X06002513
    • Cohen H, Kaplan Z, Matar MA, Loewenthal U, Zohar J, Richter-Levin G (2008a). Long-lasting behavioral effects of juvenile trauma in an animal model of PTSD associated with a failure of the autonomic nervous system to recover. Eur Neuropsychopharmacol 17: 464-477. (Pubitemid 46497658)
    • (2007) European Neuropsychopharmacology , vol.17 , Issue.6-7 , pp. 464-477
    • Cohen, H.1    Kaplan, Z.2    Matar, M.A.3    Loewenthal, U.4    Zohar, J.5    Richter-Levin, G.6
  • 11
    • 80052709724 scopus 로고    scopus 로고
    • The characteristic long-term upregulation of hippocampal NF-kappaB complex in PTSD-like behavioral stress response is normalized by high-dose corticosterone and pyrrolidine dithiocarbamate administered immediately after exposure
    • Cohen H, Kozlovsky N, Matar MA, Zohar J, Kaplan Z (2011). The characteristic long-term upregulation of hippocampal NF-kappaB complex in PTSD-like behavioral stress response is normalized by high-dose corticosterone and pyrrolidine dithiocarbamate administered immediately after exposure. Neuropsychopharmacology 36: 2286-2302.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 2286-2302
    • Cohen, H.1    Kozlovsky, N.2    Matar, M.A.3    Zohar, J.4    Kaplan, Z.5
  • 12
    • 52949115286 scopus 로고    scopus 로고
    • Early post-stressor intervention with high-dose corticosterone attenuates posttraumatic stress response in an animal model of posttraumatic stress disorder
    • Cohen H, Matar MA, Buskila D, Kaplan Z, Zohar J (2008b). Early post-stressor intervention with high-dose corticosterone attenuates posttraumatic stress response in an animal model of posttraumatic stress disorder. Biol Psychiatry 64: 708-717.
    • (2008) Biol Psychiatry , vol.64 , pp. 708-717
    • Cohen, H.1    Matar, M.A.2    Buskila, D.3    Kaplan, Z.4    Zohar, J.5
  • 13
    • 14544301822 scopus 로고    scopus 로고
    • An animal model of posttraumatic stress disorder: The use of cut-off behavioral criteria
    • DOI 10.1196/annals.1314.014
    • Cohen H, Zohar J (2004). An animal model of posttraumatic stress disorder: the use of cut-off behavioral criteria. Ann NY Acad Sci 1032: 167-178. (Pubitemid 40298469)
    • (2004) Annals of the New York Academy of Sciences , vol.1032 , pp. 167-178
    • Cohen, H.1    Zohar, J.2
  • 14
    • 33745185299 scopus 로고    scopus 로고
    • Blunted HPA axis response to stress influences susceptibility to posttraumatic stress response in rats
    • Cohen H, Zohar J, Gidron Y, Matar MA, Belkind D, Loewenthal U et al (2006). Blunted HPA axis response to stress influences susceptibility to posttraumatic stress response in rats. Biol Psychiatry 59: 1208-1218.
    • (2006) Biol Psychiatry , vol.59 , pp. 1208-1218
    • Cohen, H.1    Zohar, J.2    Gidron, Y.3    Matar, M.A.4    Belkind, D.5    Loewenthal, U.6
  • 15
    • 0348209607 scopus 로고    scopus 로고
    • The relevance of differential response to trauma in an animal model of posttraumatic stress disorder
    • DOI 10.1016/S0006-3223(02)01909-1
    • Cohen H, Zohar J, Matar M (2003). The relevance of differential response to trauma in an animal model of post-traumatic stress disorder. Biol Psychiatry 15: 463-473. (Pubitemid 36331885)
    • (2003) Biological Psychiatry , vol.53 , Issue.6 , pp. 463-473
    • Cohen, H.1    Zohar, J.2    Matar, M.3
  • 16
    • 41649109189 scopus 로고    scopus 로고
    • Post-traumatic stress behavioural responses in inbred mouse strains: Can genetic predisposition explain phenotypic vulnerability?
    • DOI 10.1017/S1461145707007912, PII S1461145707007912
    • Cohen H, Zohar J, Matar M, Loewenthal U, Kaplan Z (2007). The impact of environment factors in determining post-exposure responses in isogenic strains of mice: can genetic predisposition explain phenotypic vulnerability? Int J Neuropsychopharmacol 11: 331-349. (Pubitemid 351482499)
    • (2008) International Journal of Neuropsychopharmacology , vol.11 , Issue.3 , pp. 331-349
    • Cohen, H.1    Geva, A.B.2    Matar, M.A.3    Zohar, J.4    Kaplan, Z.5
  • 17
    • 27644446645 scopus 로고    scopus 로고
    • Unsupervised fuzzy clustering analysis supports behavioral cutoff criteria in an animal model of posttraumatic stress disorder
    • DOI 10.1016/j.biopsych.2005.04.002, PII S0006322305004348
    • Cohen H, Zohar J, Matar MA, Kaplan Z, Geva AB (2005). Unsupervised fuzzy clustering analysis supports behavioral cutoff criteria in an animal model of posttraumatic stress disorder. Biol Psychiatry 58: 640-650. (Pubitemid 41565579)
    • (2005) Biological Psychiatry , vol.58 , Issue.8 , pp. 640-650
    • Cohen, H.1    Zohar, J.2    Matar, M.A.3    Kaplan, Z.4    Geva, A.B.5
  • 18
    • 8444239739 scopus 로고    scopus 로고
    • Setting apart the affected: The use of behavioral criteria in animal models of post traumatic stress disorder
    • DOI 10.1038/sj.npp.1300523
    • Cohen H, Zohar J, Matar MA, Zeev K, Loewenthal U, Richter-Levin G (2004). Setting apart the affected: the use of behavioral criteria in animal models of post traumatic stress disorder. Neuropsychopharmacology 29: 1962-1970. (Pubitemid 39486547)
    • (2004) Neuropsychopharmacology , vol.29 , Issue.11 , pp. 1962-1970
    • Cohen, H.1    Zohar, J.2    Matar, M.A.3    Zeev, K.4    Loewenthal, U.5    Richter-Levin, G.6
  • 19
    • 0028030717 scopus 로고
    • Effects of neuropeptide Y on the electrical properties of neurons
    • DOI 10.1016/0166-2236(94)90046-9
    • Colmers WF, Bleakman D (1994). Effects of neuropeptide Y on the electrical properties of neurons. Trends Neurosci 17: 373-379. (Pubitemid 24256075)
    • (1994) Trends in Neurosciences , vol.17 , Issue.9 , pp. 373-379
    • Colmers, W.F.1    Bleakman, D.2
  • 20
    • 79958785450 scopus 로고    scopus 로고
    • Neuroprotective effect of neuropeptide y against beta-amyloid 25-35 toxicity in SH-SY5Y neuroblastoma cells is associated with increased neurotrophin production
    • Croce N, Dinallo V, Ricci V, Federici G, Caltagirone C, Bernardini S et al (2011). Neuroprotective effect of neuropeptide Y against beta-amyloid 25-35 toxicity in SH-SY5Y neuroblastoma cells is associated with increased neurotrophin production. Neurodegener Dis 8: 300-309.
    • (2011) Neurodegener Dis , vol.8 , pp. 300-309
    • Croce, N.1    Dinallo, V.2    Ricci, V.3    Federici, G.4    Caltagirone, C.5    Bernardini, S.6
  • 21
    • 0022887164 scopus 로고
    • Distribution of neuropeptide Y-like immunoreactivity in the rat central nervous system. II. Immunohistochemical analysis
    • DOI 10.1016/0306-4522(86)90057-6
    • De Quidt ME, Emson PC (1986). Distribution of neuropeptide Y-like immunoreactivity in the rat central nervous system-II. Immunohistochemical analysis. Neuroscience 18: 545-618. (Pubitemid 16062900)
    • (1986) Neuroscience , vol.18 , Issue.3 , pp. 545-618
    • De Quidt, M.E.1    Emson, P.C.2
  • 22
    • 78649254585 scopus 로고    scopus 로고
    • Exogenous neuropeptide y promotes in vivo hippocampal neurogenesis
    • (e-pub ahead of print, 21 January 2010)
    • Decressac M, Wright B, David B, Tyers P, Jaber M, Barker RA et al (2010). Exogenous neuropeptide Y promotes in vivo hippocampal neurogenesis. Hippocampus (e-pub ahead of print, 21 January 2010).
    • (2010) Hippocampus
    • Decressac, M.1    Wright, B.2    David, B.3    Tyers, P.4    Jaber, M.5    Barker, R.A.6
  • 23
    • 77950297308 scopus 로고    scopus 로고
    • Neuropeptide y (NPY) gene: Impact on emotional processing and treatment response in anxious depression
    • Domschke K, Dannlowski U, Hohoff C, Ohrmann P, Bauer J, Kugel H et al (2010). Neuropeptide Y (NPY) gene: impact on emotional processing and treatment response in anxious depression. Eur Neuropsychopharmacol 20: 301-309.
    • (2010) Eur Neuropsychopharmacol , vol.20 , pp. 301-309
    • Domschke, K.1    Dannlowski, U.2    Hohoff, C.3    Ohrmann, P.4    Bauer, J.5    Kugel, H.6
  • 25
    • 0027436962 scopus 로고
    • Dissociation between behavioral and corticosterone responses on repeated exposures to cat odor
    • DOI 10.1016/0031-9384(93)90333-B
    • File SE, Zangrossi Jr H, Sanders FL, Mabbutt PS (1993). Dissociation between behavioral and corticosterone responses on repeated exposures to cat odor. Physiol Behav 54: 1109-1111. (Pubitemid 23343130)
    • (1993) Physiology and Behavior , vol.54 , Issue.6 , pp. 1109-1111
    • File, S.E.1    Zangrossi Jr., H.2    Sanders, F.L.3    Mabbutt, P.S.4
  • 26
    • 0023621228 scopus 로고
    • Modulation of memory processing by neuropeptide Y
    • Flood JF, Hernandez EN, Morley JE. (1987). Modulation of memory processing by neuropeptide Y. Brain Res 421: 280-290. (Pubitemid 18021635)
    • (1987) Brain Research , vol.421 , Issue.1-2 , pp. 280-290
    • Flood, J.F.1    Hernandez, E.N.2    Morley, J.E.3
  • 27
    • 0032748141 scopus 로고    scopus 로고
    • Role of hypothalamic neuropeptide Y in feeding and obesity
    • DOI 10.1054/npep.1999.0057
    • Gehlert DR. (1999). Role of hypothalamic neuropeptide Y in feeding and obesity. Neuropeptides 33: 329-338. (Pubitemid 29530125)
    • (1999) Neuropeptides , vol.33 , Issue.5 , pp. 329-338
    • Gehlert, D.R.1
  • 28
    • 79957981772 scopus 로고    scopus 로고
    • Intraperitoneal injection of neuropeptide y (NPY) alters neurotrophin rat hypothalamic levels: Implications for NPY potential role in stress-related disorders
    • Gelfo F, De Bartolo P, Tirassa P, Croce N, Caltagirone C, Petrosini L et al (2011). Intraperitoneal injection of neuropeptide Y (NPY) alters neurotrophin rat hypothalamic levels: implications for NPY potential role in stress-related disorders. Peptides 32: 1320-1323.
    • (2011) Peptides , vol.32 , pp. 1320-1323
    • Gelfo, F.1    De Bartolo, P.2    Tirassa, P.3    Croce, N.4    Caltagirone, C.5    Petrosini, L.6
  • 29
    • 63449119252 scopus 로고    scopus 로고
    • Neuropeptide y modulates the antidepressant activity of imipramine in olfactory bulbectomized rats: Involvement of NPY Y1 receptors
    • Goyal SN, Upadhya MA, Kokare DM, Bhisikar SM, Subhedar NK (2009). Neuropeptide Y modulates the antidepressant activity of imipramine in olfactory bulbectomized rats: involvement of NPY Y1 receptors. Brain Res 1266: 45-53.
    • (2009) Brain Res , vol.1266 , pp. 45-53
    • Goyal, S.N.1    Upadhya, M.A.2    Kokare, D.M.3    Bhisikar, S.M.4    Subhedar, N.K.5
  • 30
    • 4344622379 scopus 로고    scopus 로고
    • The NPY system in stress, anxiety and depression
    • DOI 10.1016/j.npep.2004.05.002, PII S0143417904000319
    • Heilig M (2004). The NPY system in stress, anxiety and depression. Neuropeptides 38: 213-224. (Pubitemid 39158860)
    • (2004) Neuropeptides , vol.38 , Issue.4 , pp. 213-224
    • Heilig, M.1
  • 31
    • 0024471489 scopus 로고
    • Opposite effect of centrally administered neuropeptide Y (NPY) on the locomotor activity of spontaneously hypertensive (SH) and normal rats
    • Heilig M, Vecsei L, Widerlov E (1989). Opposite effects of centrally administered neuropeptide Y (NPY) on locomotor activity of spontaneously hypertensive (SH) and normal rats. Acta Physiol Scand 137: 243-248. (Pubitemid 19258517)
    • (1989) Acta Physiologica Scandinavica , vol.137 , Issue.2 , pp. 243-248
    • Heilig, M.1    Vecsei, L.2    Widerlov, E.3
  • 32
    • 0028799150 scopus 로고
    • Neurobiology and clinical aspects of neuropeptide y
    • Heilig M, Widerlöv E (1995). Neurobiology and clinical aspects of neuropeptide Y. Crit Rev Neurobiol 9: 115-136.
    • (1995) Crit Rev Neurobiol , vol.9 , pp. 115-136
    • Heilig, M.1    Widerlöv, E.2
  • 33
    • 9144240389 scopus 로고    scopus 로고
    • Decreased cerebrospinal fluid neuropeptide Y (NPY) in patients with treatment refractory unipolar major depression: Preliminary evidence for association with preproNPY gene polymorphism
    • DOI 10.1016/S0022-3956(03)00101-8
    • Heilig M, Zachrisson O, Thorsell A, Ehnvall A, Mottagui-Tabar S, Sjogren M et al (2004). Decreased cerebrospinal fluid neuropeptide Y (NPY) in patients with treatment refractory unipolar major depression: preliminary evidence for association with preproNPY gene polymorphism. J Psychiatr Res 38: 113-121. (Pubitemid 38134451)
    • (2004) Journal of Psychiatric Research , vol.38 , Issue.2 , pp. 113-121
    • Heilig, M.1    Zachrisson, O.2    Thorsell, A.3    Ehnvall, A.4    Mottagui-Tabar, S.5    Sjogren, M.6    Asberg, M.7    Ekman, R.8    Wahlestedt, C.9    Agren, H.10
  • 35
    • 0034927081 scopus 로고    scopus 로고
    • Neurotrophins: Roles in neuronal development and function
    • DOI 10.1146/annurev.neuro.24.1.677
    • Huang EJ, Reichardt LF (2001). Neurotrophins: roles in neuronal development and function. Annu Rev Neurosci 24: 677-736. (Pubitemid 32695243)
    • (2001) Annual Review of Neuroscience , vol.24 , pp. 677-736
    • Huang, E.J.1    Reichardt, L.F.2
  • 36
    • 33750487468 scopus 로고    scopus 로고
    • Exacerbated loss of cell survival, neuropeptide Y-immunoreactive (IR) cells, and serotonin-IR fiber lengths in the dorsal hippocampus of the aged Flinders sensitive line "depressed" rat: Implications for the pathophysiology of depression?
    • DOI 10.1002/jnr.21027
    • Husum H, Aznar S, Hoyer-Hansen S, Larsen MH, Mikkelsen JD, Moller A et al (2006). Exacerbated loss of cell survival, neuropeptide Y-immunoreactive (IR) cells, and serotonin-IR fiber lengths in the dorsal hippocampus of the aged flinders sensitive line 'depressed' rat: Implications for the pathophysiology of depression? J Neurosci Res 84: 1292-1302. (Pubitemid 44654452)
    • (2006) Journal of Neuroscience Research , vol.84 , Issue.6 , pp. 1292-1302
    • Husum, H.1    Aznar, S.2    Hoyer-Hansen, S.3    Larsen, M.H.4    Mikkelsen, J.D.5    Moller, A.6    Mathe, A.A.7    Wortwein, G.8
  • 37
    • 0036848459 scopus 로고    scopus 로고
    • Early life stress changes concentrations of neuropeptide Y and corticotropin-releasing hormone in adult rat brain. Lithium treatment modifies these changes
    • DOI 10.1016/S0893-133X(02)00363-9, PII S0893133X02003639
    • Husum H, Mathé AA (2002). Early life stress changes concentrations of neuropeptide Y and corticotropin-releasing hormone in adult rat brain. Lithium treatment modifies these changes. Neuropsychopharmacology 27: 756-764. (Pubitemid 35335892)
    • (2002) Neuropsychopharmacology , vol.27 , Issue.5 , pp. 756-764
    • Husum, H.1    Mathe, A.A.2
  • 38
    • 33846401789 scopus 로고    scopus 로고
    • 1 receptor gene expressions in hippocampus and hypothalamus of Flinders Sensitive Line rat model of depression
    • DOI 10.1016/j.euroneuro.2006.06.011, PII S0924977X06001295
    • Jimenez-Vasquez PA, Diaz-Cabiale Z, Caberlotto L, Bellido I, Overstreet D, Fuxe K et al (2007). Electroconvulsive stimuli selectively affect behavior and neuropeptide Y (NPY) and NPY Y(1) receptor gene expressions in hippocampus and hypothalamus of Flinders Sensitive Line rat model of depression. Eur Neuropsychopharmacol 17: 298-308. (Pubitemid 46135933)
    • (2007) European Neuropsychopharmacology , vol.17 , Issue.4 , pp. 298-308
    • Jimenez-Vasquez, P.A.1    Diaz-Cabiale, Z.2    Caberlotto, L.3    Bellido, I.4    Overstreet, D.5    Fuxe, K.6    Mathe, A.A.7
  • 39
    • 0035955930 scopus 로고    scopus 로고
    • Early maternal separation alters neuropeptide Y concentrations in selected brain regions in adult rats
    • DOI 10.1016/S0165-3806(01)00264-4, PII S0165380601002644
    • Jimenez-Vasquez PA, Mathé AA, Thomas JD, Riley EP, Ehlers CL (2001). Early maternal separation alters neuropeptide Y concentrations in selected brain regions in adult rats. Brain Res Dev Brain Res 131: 149-152. (Pubitemid 33079226)
    • (2001) Developmental Brain Research , vol.131 , Issue.1-2 , pp. 149-152
    • Jimenez-Vasquez, P.A.1    Mathe, A.A.2    Thomas, J.D.3    Riley, E.P.4    Ehlers, C.L.5
  • 40
    • 0028351190 scopus 로고
    • Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development
    • DOI 10.1016/0092-8674(94)90377-8
    • Jones KR, Farinas I, Backus C, Reichardt LF (1994). Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development. Cell 76: 989-999. (Pubitemid 24106380)
    • (1994) Cell , vol.76 , Issue.6 , pp. 989-999
    • Jones, K.R.1    Farinas, I.2    Backus, C.3    Reichardt, L.F.4
  • 41
    • 0033038418 scopus 로고    scopus 로고
    • Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
    • DOI 10.1210/er.20.1.68
    • Kalra SP, Dube MG, Pu S, Xu B, Horvath TL (1999). Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20: 68-100. (Pubitemid 29092036)
    • (1999) Endocrine Reviews , vol.20 , Issue.1 , pp. 68-100
    • Kalra, S.P.1    Dube, M.G.2    Pu, S.3    Xu, B.4    Horvath, T.L.5    Kalra, P.S.6
  • 42
    • 36348958594 scopus 로고    scopus 로고
    • The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice
    • DOI 10.1007/s00213-007-0945-2
    • Karlsson RM, Choe JS, Cameron HA, Thorsell A, Crawley JN, Holmes A et al (2008). The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice. Psychopharmacology (Berl) 195: 547-557. (Pubitemid 350160495)
    • (2008) Psychopharmacology , vol.195 , Issue.4 , pp. 547-557
    • Karlsson, R.-M.1    Choe, J.S.2    Cameron, H.A.3    Thorsell, A.4    Crawley, J.N.5    Holmes, A.6    Heilig, M.7
  • 43
    • 0036111124 scopus 로고    scopus 로고
    • The neurocircuitry and receptor subtypes mediating anxiolytic-like effects of neuropeptide Y
    • DOI 10.1016/S0149-7634(01)00066-5, PII S0149763401000665
    • Kask A, Harro J, von Horsten S, Redrobe JP, Dumont Y, Quirion R (2002). The neurocircuitry and receptor subtypes mediating anxiolytic-like effects of neuropeptide Y. Neurosci Biobehav Rev 26: 259-283. (Pubitemid 34555409)
    • (2002) Neuroscience and Biobehavioral Reviews , vol.26 , Issue.3 , pp. 259-283
    • Kask, A.1    Harro, J.2    Von Horsten, S.3    Redrobe, J.P.4    Dumont, Y.5    Quirion, R.6
  • 44
    • 0030593905 scopus 로고    scopus 로고
    • 1 receptor antagonist BLBP3226: Antagonism with diazepam
    • DOI 10.1016/S0014-2999(96)00838-2, PII S0014299996008382
    • Kask A, Rago L, Harro J (1996). Anxiogenic-like effect of the neuropeptide Y Y1 receptor antagonist BIBP 3226: antagonism with diazepam. Eur J Pharmacol 317: R3-R4. (Pubitemid 27014053)
    • (1996) European Journal of Pharmacology , vol.317 , Issue.2-3
    • Kask, A.1    Rago, L.2    Harro, J.3
  • 45
    • 0026652052 scopus 로고
    • Selective impairment of long-term but not short-term conditional fear by the N-methyl-D-aspartate antagonist APV
    • Kim JJ, Fanselow MS, DeCola JP, Landeira-Fernandez J (1992). Selective impairment of long-term but not short-term conditional fear by the N-methyl-D-aspartate antagonist APV. Behav Neurosci 106: 591-596.
    • (1992) Behav Neurosci , vol.106 , pp. 591-596
    • Kim, J.J.1    Fanselow, M.S.2    Decola, J.P.3    Landeira-Fernandez, J.4
  • 46
    • 0037198404 scopus 로고    scopus 로고
    • Expression of the neuropeptide Y Y1 receptor in the CNS of rat and of wild-type and Y1 receptor knock-out mice. Focus on immunohistochemical localization
    • DOI 10.1016/S0306-4522(01)00463-8, PII S0306452201004638
    • Kopp J, Xu ZQ, Zhang X, Pedrazzini T, Herzog H, Kresse A et al (2002). Expression of the neuropeptide Y Y1 receptor in the CNS of rat and of wild-type and Y1 receptor knock-out mice. Focus on immunohistochemical localization. Neuroscience 111: 443-532. (Pubitemid 34521893)
    • (2002) Neuroscience , vol.111 , Issue.3 , pp. 443-532
    • Kopp, J.1    Xu, Z.-Q.2    Zhang, X.3    Pedrazzini, T.4    Herzog, H.5    Kresse, A.6    Wong, H.7    Walsh, J.H.8    Hokfelt, T.9
  • 47
    • 0033023467 scopus 로고    scopus 로고
    • Interactions between the neuropeptide Y system and the hypothalamic- pituitary-adrenal axis
    • DOI 10.1530/eje.0.1400130
    • Krysiak R, Obuchowicz E, Herman ZS (1999). Interactions between the neuropeptide Y system and the hypothalamic-pituitaryadrenal axis. Eur J Endocrinol 140: 130-136. (Pubitemid 29090439)
    • (1999) European Journal of Endocrinology , vol.140 , Issue.2 , pp. 130-136
    • Krysiak, R.1    Obuchowicz, E.2    Herman, Z.S.3
  • 48
    • 0034651078 scopus 로고    scopus 로고
    • BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain
    • Mamounas LA, Altar CA, Blue ME, Kaplan DR, Tessarollo L, Lyons WE (2000). BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain. J Neurosci 20: 771-782. (Pubitemid 30225579)
    • (2000) Journal of Neuroscience , vol.20 , Issue.2 , pp. 771-782
    • Mamounas, L.A.1    Altar, C.A.2    Blue, M.E.3    Kaplan, D.R.4    Tessarollo, L.5    Lyons, W.E.6
  • 49
    • 0032982595 scopus 로고    scopus 로고
    • Neuropeptides and electroconvulsive treatment
    • Mathé A (1999). Neuropeptides and electroconvulsive treatment. J ECT 15: 60-75. (Pubitemid 29318094)
    • (1999) Journal of ECT , vol.15 , Issue.1 , pp. 60-75
    • Mathe, A.A.1
  • 50
    • 0030968416 scopus 로고    scopus 로고
    • Effects of electroconvulsive stimuli and MK-801 on neuropeptide Y, neurokinin A, and calcitonin gene-related peptide in rat brain
    • Mathé A, Gruber S, Jiménesz P, Theodorsson E, Stenfors C (1997). Effect of electroconvulsive stimuli and MK-801 on neuropeptide Y, neurokinin A, calcitonin gene-related peptide in rat brain. Neurochem Res 22: 629-636. (Pubitemid 27184693)
    • (1997) Neurochemical Research , vol.22 , Issue.5 , pp. 629-636
    • Mathe, A.A.1    Gruber, S.2    Jimenez, P.A.3    Theodorsson, E.4    Stenfors, C.5
  • 52
    • 0029608661 scopus 로고    scopus 로고
    • Effects of electroconvulsive treatment on somatostatin, neuropeptide Y, endothelin and neurokinin A concentration in cerebrospinal fluid of depressed patients
    • Mathé A, Rudorfer M, Stenfors C,Manji H, PotterW, Theodorsson E (1996). Effects of electroconvulsive treatment on somatostatin, neuropeptide Y, endothelin and neurokinin A concentration in cerebrospinal fluid of depressed patients. Depression 3: 250-257.
    • (1996) Depression , vol.3 , pp. 250-257
    • Mathé, A.1    Rudorfer, M.2    Stenfors, C.3    Manji, H.4    Potter, W.5    Theodorsson, E.6
  • 53
    • 77949527334 scopus 로고    scopus 로고
    • Gender-related qualitative differences in baseline and post-stress anxiety responses are not reflected in the incidence of criterion-based PTSD-like behaviour patterns
    • Mazor A, Matar MA, Kaplan Z, Kozlovsky N, Zohar J, Cohen H (2007). Gender-related qualitative differences in baseline and post-stress anxiety responses are not reflected in the incidence of criterion-based PTSD-like behaviour patterns. World J Biol Psychiatry 10: 856-869.
    • (2007) World J Biol Psychiatry , vol.10 , pp. 856-869
    • Mazor, A.1    Matar, M.A.2    Kaplan, Z.3    Kozlovsky, N.4    Zohar, J.5    Cohen, H.6
  • 55
    • 78650893910 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and hypothalamic-pituitaryadrenal axis adaptation processes in a depressive-like state induced by chronic restraint stress
    • Naert G, Ixart G, Maurice T, Tapia-Arancibia L, Givalois L (2011). Brain-derived neurotrophic factor and hypothalamic-pituitaryadrenal axis adaptation processes in a depressive-like state induced by chronic restraint stress. Mol Cell Neurosci 46: 55-66.
    • (2011) Mol Cell Neurosci , vol.46 , pp. 55-66
    • Naert, G.1    Ixart, G.2    Maurice, T.3    Tapia-Arancibia, L.4    Givalois, L.5
  • 56
    • 0027511128 scopus 로고
    • Regulation of neuropeptide expression in cultured cerebral cortical neurons by brain-derived neurotrophic factor
    • DOI 10.1111/j.1471-4159.1993.tb03216.x
    • Nawa H, Bessho Y, Carnahan J, Nakanishi S, Mizuno K (1993). Regulation of neuropeptide expression in cultured cerebral cortical neurons by brain-derived neurotrophic factor. J Neurochem 60: 772-775. (Pubitemid 23030982)
    • (1993) Journal of Neurochemistry , vol.60 , Issue.2 , pp. 772-775
    • Nawa, H.1    Bessho, Y.2    Carnahan, J.3    Nakanishi, S.4    Mizuno, K.5
  • 57
    • 0028298924 scopus 로고
    • Intraventricular administration of BDNF increases neuropeptide expression in newborn rat brain
    • Nawa H, Pelleymounter MA, Carnahan J (1994). Intraventricular administration of BDNF increases neuropeptide expression in newborn rat brain. J Neurosci 14: 3751-3765. (Pubitemid 24174121)
    • (1994) Journal of Neuroscience , vol.14 , Issue.6 , pp. 3751-3765
    • Nawa, H.1    Pelleymounter, M.A.2    Carnahan, J.3
  • 59
    • 22344449436 scopus 로고    scopus 로고
    • Neuropeptide Y and corticotropin-releasing hormone in CSF mark response to antidepressive treatment with citalopram
    • DOI 10.1017/S1461145705005158
    • Nikisch G, Agren H, Eap CB, Czernik A, Baumann P, Mathe AA (2005). Neuropeptide Y and corticotropin-releasing hormone in CSF mark response to antidepressive treatment with citalopram. Int J Neuropsychopharmacol 8: 403-410. (Pubitemid 41002494)
    • (2005) International Journal of Neuropsychopharmacology , vol.8 , Issue.3 , pp. 403-410
    • Nikisch, G.1    Agren, H.2    Eap, C.B.3    Czernik, A.4    Baumann, P.5    Mathe, A.A.6
  • 62
    • 70449704038 scopus 로고    scopus 로고
    • Effect of pharmacological manipulations of neuropeptide y and corticotropin-releasing factor neurotransmission on incubation of conditioned fear
    • Pickens CL, Adams-Deutsch T, Nair SG, Navarre BM, Heilig M, Shaham Y (2009). Effect of pharmacological manipulations of neuropeptide Y and corticotropin-releasing factor neurotransmission on incubation of conditioned fear. Neuroscience 164: 1398-1406.
    • (2009) Neuroscience , vol.164 , pp. 1398-1406
    • Pickens, C.L.1    Adams-Deutsch, T.2    Nair, S.G.3    Navarre, B.M.4    Heilig, M.5    Shaham, Y.6
  • 63
    • 0035234670 scopus 로고    scopus 로고
    • Neurotrophins as synaptic modulators
    • Poo MM (2001). Neurotrophins as synaptic modulators. Nat Rev Neurosci 2: 24-32.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 24-32
    • Poo, M.M.1
  • 64
    • 27744482873 scopus 로고    scopus 로고
    • Effects of altered amygdalar neuropeptide Y expression on anxiety-related behaviors
    • DOI 10.1038/sj.npp.1300705, PII 1300705
    • Primeaux SD, Wilson SP, Cusick MC, York DA, Wilson MA (2005). Effects of altered amygdalar neuropeptide Y expression on anxietyrelated behaviors. Neuropsychopharmacology 30: 1589-1597. (Pubitemid 43086016)
    • (2005) Neuropsychopharmacology , vol.30 , Issue.9 , pp. 1589-1597
    • Primeaux, S.D.1    Wilson, S.P.2    Cusick, M.C.3    York, D.A.4    Wilson, M.A.5
  • 65
    • 0343920026 scopus 로고    scopus 로고
    • Low baseline and yohimbine-stimulated plasma neuropeptide Y (NPY) levels in combat-related PTSD
    • DOI 10.1016/S0006-3223(99)00185-7, PII S0006322399001857
    • Rasmusson AM, Hauger RL, Morgan CA, Bremner JD, Charney DS, Southwick SM (2000). Low baseline and yohimbine-stimulated plasma neuropeptide Y (NPY) levels in combat-related PTSD. Biol Psychiatry 47: 526-539. (Pubitemid 30129081)
    • (2000) Biological Psychiatry , vol.47 , Issue.6 , pp. 526-539
    • Rasmusson, A.M.1    Hauger, R.L.2    Morgan III, C.A.3    Bremner, J.D.4    Charney, D.S.5    Southwick, S.M.6
  • 66
    • 0033457358 scopus 로고    scopus 로고
    • Multiple receptors for neuropeptide Y in the hippocampus: Putative roles in seizures and cognition
    • DOI 10.1016/S0006-8993(99)02119-8, PII S0006899399021198
    • Redrobe JP, Dumont Y, St-Pierre JA, Quirion R (1999). Multiple receptors for neuropeptide Y in the hippocampus: putative roles in seizures and cognition. Brain Res 848: 153-166. (Pubitemid 30001664)
    • (1999) Brain Research , vol.848 , Issue.1-2 , pp. 153-166
    • Redrobe, J.P.1    Dumont, Y.2    St-Pierre, J.-A.3    Quirion, R.4
  • 67
    • 69749125954 scopus 로고    scopus 로고
    • Low cerebrospinal fluid neuropeptide y concentrations in posttraumatic stress disorder
    • Sah R, Ekhator NN, Strawn JR, Sallee FR, Baker DG, Horn PS et al (2009). Low cerebrospinal fluid neuropeptide Y concentrations in posttraumatic stress disorder. Biol Psychiatry 66: 705-707.
    • (2009) Biol Psychiatry , vol.66 , pp. 705-707
    • Sah, R.1    Ekhator, N.N.2    Strawn, J.R.3    Sallee, F.R.4    Baker, D.G.5    Horn, P.S.6
  • 68
    • 38549123307 scopus 로고    scopus 로고
    • Neuropeptide Y in the amygdala induces long-term resilience to stress-induced reductions in social responses but not hypothalamic-adrenal- pituitary axis activity or hyperthermia
    • DOI 10.1523/JNEUROSCI.0659-07.2008
    • Sajdyk TJ, Johnson PL, Leitermann RJ, Fitz SD, Dietrich A, Morin M et al (2008). Neuropeptide Y in the amygdala induces long-term resilience to stress-induced reductions in social responses but not hypothalamic-adrenal- pituitary axis activity or hyperthermia. J Neurosci 28: 893-903. (Pubitemid 351159007)
    • (2008) Journal of Neuroscience , vol.28 , Issue.4 , pp. 893-903
    • Sajdyk, T.J.1    Johnson, P.L.2    Leitermann, R.J.3    Fitz, S.D.4    Dietrich, A.5    Morin, M.6    Gehlert, D.R.7    Urban, J.H.8    Shekhar, A.9
  • 69
    • 0033054619 scopus 로고    scopus 로고
    • 1 receptors mediate the anxiolytic-like actions of neuropeptide Y in the social interaction test
    • DOI 10.1016/S0014-2999(99)00018-7, PII S0014299999000187
    • Sajdyk TJ, Vandergriff MG, Gehlert DR (1999). Amygdalar neuropeptide Y Y1 receptors mediate the anxiolytic-like actions of neuropeptide Y in the social interaction test. Eur J Pharmacol 368: 143-147. (Pubitemid 29117135)
    • (1999) European Journal of Pharmacology , vol.368 , Issue.2-3 , pp. 143-147
    • Sajdyk, T.J.1    Vandergriff, M.G.2    Gehlert, D.R.3
  • 70
    • 43849094305 scopus 로고    scopus 로고
    • Neuropeptide Y mediates the initial hypothalamic-pituitary-adrenal response to maternal separation in the neonatal mouse
    • DOI 10.1677/JOE-07-0634
    • Schmidt MV, Liebl C, Sterlemann V, Ganea K, Hartmann J, Harbich D et al (2008). Neuropeptide Y mediates the initial hypothalamic-pituitary-adrenal response to maternal separation in the neonatal mouse. J Endocrinol 197: 421-427. (Pubitemid 351696255)
    • (2008) Journal of Endocrinology , vol.197 , Issue.2 , pp. 421-427
    • Schmidt, M.V.1    Liebl, C.2    Sterlemann, V.3    Ganea, K.4    Hartmann, J.5    Harbich, D.6    Alam, S.7    Muller, M.B.8
  • 72
    • 0032865843 scopus 로고    scopus 로고
    • Molecular mechanisms underlying activity-dependent regulation of BDNF expression
    • DOI 10.1002/(SICI)1097-4695(199910)41:1<127::AID-NEU16>3.0.CO;2-J
    • Shieh PB, Ghosh A (1999). Molecular mechanisms underlying activity-dependent regulation of BDNF expression. J Neurobiol 41: 127-134. (Pubitemid 29467612)
    • (1999) Journal of Neurobiology , vol.41 , Issue.1 , pp. 127-134
    • Shieh, P.B.1    Ghosh, A.2
  • 74
    • 0024306940 scopus 로고
    • Effect of repeated electroconvulsive treatment on regional concentrations of tachykinins, neurotensin, vasoactive intestinal polypeptide, neuropeptide Y, and galanin in rat brain
    • DOI 10.1002/jnr.490240315
    • Stenfors C, Theodorsson E, Mathe AA (1989). Effect of repeated electroconvulsive treatment on regional concentrations of tachykinins, neurotensin, vasoactive intestinal polypeptide, neuropeptide Y, and galanin in rat brain. J Neurosci Res 24: 445-450. (Pubitemid 20001458)
    • (1989) Journal of Neuroscience Research , vol.24 , Issue.3 , pp. 445-450
    • Stenfors, G.1    Theodorsson, E.2    Mathe, A.A.3
  • 75
    • 0034589372 scopus 로고    scopus 로고
    • Neurotrophins and activity-dependent plasticity
    • DOI 10.1016/S0079-6123(00)28016-3
    • Thoenen H (2000). Neurotrophins and activity-dependent plasticity. Prog Brain Res 128: 183-191. (Pubitemid 35461235)
    • (2000) Progress in Brain Research , vol.128 , pp. 183-191
    • Thoenen, H.1
  • 76
    • 0033732324 scopus 로고    scopus 로고
    • Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide y overexpression
    • Thorsell A, Michalkiewicz M, Dumont Y, Quirion R, Caberlotto L, Rimondini R et al (2000). Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression. Proc Natl Acad Sci USA 97: 12852-12857.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12852-12857
    • Thorsell, A.1    Michalkiewicz, M.2    Dumont, Y.3    Quirion, R.4    Caberlotto, L.5    Rimondini, R.6
  • 77
    • 0027450169 scopus 로고
    • Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides
    • Wahlestedt C, PiIch E, Koob G, Yee F, Heilig M (1993). Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides. Science 259: 528-531. (Pubitemid 23058713)
    • (1993) Science , vol.259 , Issue.5094 , pp. 528-531
    • Wahlestedt, C.1    Pich, E.M.2    Koob, G.F.3    Yee, F.4    Heilig, M.5
  • 78
    • 0027453750 scopus 로고
    • Neuropeptide Y: A central regulator of energy homeostasis
    • White J (1993). Neuropeptide Y: a central regulator of energy homeostasis. Regul Pept 49: 93-107.
    • (1993) Regul Pept , vol.49 , pp. 93-107
    • White, J.1
  • 80
    • 33644817491 scopus 로고    scopus 로고
    • Plasma neuropeptide Y concentrations in combat exposed veterans: Relationship to trauma exposure, recovery from PTSD, and coping
    • DOI 10.1016/j.biopsych.2005.08.027, PII S0006322305012151
    • Yehuda R, Brand S, Yang RK (2006). Plasma neuropeptide Y concentrations in combat exposed veterans: relationship to trauma exposure, recovery from PTSD, and coping. Biol Psychiatry 59: 660-663. (Pubitemid 43357961)
    • (2006) Biological Psychiatry , vol.59 , Issue.7 , pp. 660-663
    • Yehuda, R.1    Brand, S.2    Yang, R.-K.3


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