Intraperitoneal injection of neuropeptide y (NPY) alters neurotrophin rat hypothalamic levels: Implications for NPY potential role in stress-related disorders

Peptides

Volumn 32, Issue 6, 2011, Pages 1320-1323

  Gelfo, Francesca ^a   De Bartolo, Paola ^a,c   Tirassa, Paola ^b   Croce, Nicoletta ^a   Caltagirone, Carlo ^a   Petrosini, Laura ^a,c   Angelucci, Francesco ^a  

^a IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^b CNR   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

BDNF; Hypothalamus; Neuropeptide Y; Neurotrophins; NGF

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR; NEUROPEPTIDE Y; NEUROTROPHIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HYPOTHALAMUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN SYNTHESIS; RAT; STRESS;

ANIMALS; ANTIDEPRESSIVE AGENTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INJECTIONS, INTRAPERITONEAL; MALE; NERVE GROWTH FACTOR; NEUROPEPTIDE Y; PITUITARY-ADRENAL SYSTEM; RATS; RATS, WISTAR; STRESS DISORDERS, TRAUMATIC; UP-REGULATION;

RATTUS;

EID: 79957981772     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2011.03.023     Document Type: Article

References (43)

1. E. Alleva, and D. Santucci Psychosocial vs. "physical" stress situations in rodents and humans: role of neurotrophins Physiol Behav 73 2001 313 320 (Pubitemid 32595704)
2. I.A. Antonijevic, H. Murck, S. Bohlhalter, R.M. Frieboes, F. Holsboer, and A. Steiger Neuropeptide Y promotes sleep and inhibits ACTH and cortisol release in young men Neuropharmacology 39 2000 1474 1481 (Pubitemid 30249209)
3. L. Arborelius, M.J. Owens, P.M. Plotsky, and C.B. Nemeroff The role of corticotropin-releasing factor in depression and anxiety disorders J Endocrinol 160 1999 1 12 (Pubitemid 29044562)
4. E. Badowska-Szalewska, I. Klejbor, B. Ludkiewicz, B. Domaradzka-Pytel, J. Dziewiatkowski, and J.H. Spodnik Immunoreactivity of c-Fos NGF and its receptor TrkA in the periventricular zone of the rat hypothalamus after open field exposure Pol J Vet Sci 9 2006 171 180 (Pubitemid 44432647)
5. B. Beck Neuropeptide Y in normal eating and in genetic and dietary-induced obesity Philos Trans R Soc Lond B Biol Sci 361 2006 1159 1185 (Pubitemid 44874227)
6. A. Bjørnebekk, A.A. Mathé, and S. Brené The antidepressant effects of running and escitalopram are associated with levels of hippocampal NPY and Y1 receptor but not cell proliferation in a rat model of depression Hippocampus 20 2010 820 828
7. K.T. Britton, S. Southerland, E. Van Uden, D. Kirby, J. Rivier, and G. Koob Anxiolytic activity of NPY receptor agonists in the conflict test Psychopharmacology (Berl) 132 1997 6 13 (Pubitemid 27303733)
8. K.T. Britton, Y. Akwa, M.G. Spina, and G.F. Koob Neuropeptide Y blocks anxiogenic-like behavioral action of corticotropin-releasing factor in an operant conflict test and elevated plus maze Peptides 21 2000 37 44 (Pubitemid 30126040)
9. M.J. Chee, M.G. Myers Jr., C.J. Price, and W.F. Colmers Neuropeptide Y suppresses anorexigenic output from the ventromedial nucleus of the hypothalamus J Neurosci 30 2010 3380 3390
10. C.L. Ehlers, C. Somes, E. Seifritz, and J.E. Rivier CRF/NPY interactions: a potential role in sleep dysregulation in depression and anxiety Depress Anxiety 6 1997 1 9 (Pubitemid 28079905)
11. B. Elfving, P.H. Plougmann, H.K. Müller, A.A. Mathé, R. Rosenberg, and G. Wegener Inverse correlation of brain and blood BDNF levels in a genetic rat model of depression Int J Neuropsychopharmacol 13 2010 563 572
12. L. Givalois, G. Naert, F. Rage, G. Ixart, S. Arancibia, and L. Tapia-Arancibia A single brain-derived neurotrophic factor injection modifies hypothalamo-pituitary-adrenocortical axis activity in adult male rats Mol Cell Neurosci 27 2004 280 295 (Pubitemid 39433842)
13. J. Glowinski, and L.L. Iversen Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain J Neurochem 13 1966 655 669
14. A.C. Hansson, R. Rimondini, M. Heilig, A.A. Mathé, and W.H. Sommer Dissociation of antidepressant-like activity of escitalopram and nortriptyline on behaviour and hippocampal BDNF expression in female rats J Psychopharmacol 2011 [Epub ahead of print]
15. K. Hashimoto Brain-derived neurotrophic factor as a biomarker for mood disorders: an historical overview and future directions Psychiatry Clin Neurosci 64 2010 341 357
16. M. Heilig The NPY system in stress, anxiety and depression Neuropeptides 38 2004 213 224 (Pubitemid 39158860)
17. P.A. Jiménez-Vasquez, Z. Diaz-Cabiale, L. Caberlotto, I. Bellido, D. Overstreet, and K. Fuxe Electroconvulsive stimuli selectively affect behavior and neuropeptide Y (NPY) and NPY Y(1) receptor gene expressions in hippocampus and hypothalamus of Flinders Sensitive Line rat model of depression Eur Neuropsychopharmacol 17 2007 298 308 (Pubitemid 46135933)
18. M.C. Jockers-Scherübl, D. Zubraegel, T. Baer, M. Linden, H. Danker-Hopfe, and O. Schulte-Herbrüggen Nerve growth factor serum concentrations rise after successful cognitive-behavioural therapy of generalized anxiety disorder Prog Neuropsychopharmacol Biol Psychiatry 31 2007 200 204 (Pubitemid 44970510)
19. K. Kaczyńska, and M. Szereda-Przestaszewska NPY Y(1) receptors are involved in cardio-respiratory responses to intravenous injection of neuropeptide Y in anaesthetized rats Pharmacol Res 62 2010 444 449
20. A. Kask, L. Rägo, and J. Harro Alpha-helical CRF(9-41) prevents anxiogenic-like effect of NPY Y1 receptor antagonist BIBP3226 in rats Neuroreport 8 1997 3645 3647 (Pubitemid 27497499)
21. A.J. Kastin, and V. Akerstrom Nonsaturable entry of neuropeptide Y into brain Am J Physiol 276 1999 E479 E482
22. A.J. Kastin, and W. Pan Blood-brain barrier and feeding: regulatory roles of saturable transport systems for ingestive peptides Curr Pharm Des 14 2008 1615 1619 (Pubitemid 352002989)
23. P.J. Larsen, K.E. Jukes, H.S. Chowdrey, S.L. Lightman, and D.S. Jessop Neuropeptide-Y potentiates the secretion of vasopressin from the neurointermediate lobe of the rat pituitary gland Endocrinology 134 1994 1635 1639 (Pubitemid 24110717)
24. L. Marais, S.J. van Rensburg, J.M. van Zyl, D.J. Stein, and W.M. Daniels Maternal separation of rat pups increases the risk of developing depressive-like behavior after subsequent chronic stress by altering corticosterone and neurotrophin levels in the hippocampus Neurosci Res 61 2008 106 112
25. K. Martinowich, H. Manji, and B. Lu New insights into BDNF function in depression and anxiety Nat Neurosci 10 2007 1089 1093 (Pubitemid 47339961)
26. G. Mazzocchi, L.K. Malendowicz, C. Macchi, G. Gottardo, and G.G. Nussdorfer Further investigations on the effects of neuropeptide Y on the secretion and growth of rat adrenal zona glomerulosa Neuropeptides 30 1996 19 27 (Pubitemid 26086431)
27. A.A. Mello, M.F. Mello, L.L. Carpenter, and L.H. Price Update on stress and depression:the role of the hypothalamic-pituitary-adrenal (HPA) axis Rev Bras Psiquiatr 25 2003 231 238 (Pubitemid 37376769)
28. R. Moriya, T. Shirakura, H. Hirose, T. Kanno, J. Suzuki, and A. Kanatani NPY Y2 receptor agonist PYY(3-36) inhibits diarrhea by reducing intestinal fluid secretion and slowing colonic transit in mice Peptides 31 2010 671 675
29. G. Naert, G. Ixart, L. Tapia-Arancibia, and L. Givalois Continuous i.c.v. infusion of brain-derived neurotrophic factor modifies hypothalamic-pituitary- adrenal axis activity, locomotor activity and body temperature rhythms in adult male rats Neuroscience 139 2006 779 789
30. G. Naert, G. Ixart, T. Maurice, L. Tapia-Arancibia, and L. Givalois Brain-derived neurotrophic factor and hypothalamic-pituitary-adrenal axis adaptation processes in a depressive-like state induced by chronic restraint stress Mol Cell Neurosci 46 2011 55 66
31. G. Nikisch, H. Agren, C.B. Eap, A. Czernik, P. Baumann, and A.A. Mathé Neuropeptide Y and corticotropin-releasing hormone in CSF mark response to antidepressive treatment with citalopram Int J Neuropsychopharmacol 8 2005 403 410 (Pubitemid 41002494)
32. G. Nikisch, and A.A. Mathé CSF monoamine metabolites and neuropeptides in depressed patients before and after electroconvulsive therapy Eur Psychiatry 23 2008 356 359
33. K.A. Paschos, S. Veletza, and E. Chatzaki Neuropeptide and sigma receptors as novel therapeutic targets for the pharmacotherapy of depression CNS Drugs 23 2009 755 772
34. F. Rage, L. Givalois, F. Marmigre, L. Tapia-Arancibia, and S. Arancibia Immobilization stress rapidly modulates BDNF mRNA expression in the hypothalamus of adult male rats Neuroscience 112 2002 309 318 (Pubitemid 34607015)
35. K. Sato, J.T. Crofton, Y.X. Wang, and L. Share Effects of gender on the central actions of neuropeptide Y and norepinephrine on vasopressin and blood pressure in the rat Brain Res 689 1995 71 78
36. S. Scaccianoce, K. Lombardo, R. Nicolai, D. Affricano, and L. Angelucci Studies on the involvement of histamine in the hypothalamic-pituitary-adrenal axis activation induced by nerve growth factor Life Sci 67 2000 3143 3152
37. K.A. Simpson, N.M. Martin, and S.R. Bloom Hypothalamic regulation of food intake and clinical therapeutic applications Arq Bras Endocrinol Metabol 53 2009 120 128
38. M.A. Smith, S. Makino, S.Y. Kim, and R. Kvetnansky Stress increases brain-derived neurotrophic factor messenger ribonucleic acid in the hypothalamus and pituitary Endocrinology 136 1995 3743 3750
39. L. Tapia-Arancibia, F. Rage, L. Givalois, and S. Arancibia Physiology of BDNF: focus on hypothalamic function Front Neuroendocrinol 25 2004 77 107 (Pubitemid 39582717)
40. A. Thorsell, C.J. Slawecki, and C.L. Ehlers Effects of neuropeptide Y and corticotropin-releasing factor on ethanol intake in Wistar rats: interaction with chronic ethanol exposure Behav Brain Res 161 2005 133 140 (Pubitemid 40719780)
41. C. Tsigos, and G.P. Chrousos Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress J Psychosom Res 53 2002 865 871 (Pubitemid 35282615)
42. D.M. Weisenhorn, J. Roback, A.N. Young, and B.H. Wainer Cellular aspects of trophic actions in the nervous system Int Rev Cytol 189 1999 177 265 (Pubitemid 29196966)
43. A.W. Zhou, W.X. Li, J. Guo, and Y.C. Du Facilitation of AVP(4-8) on gene expression of BDNF and NGF in rat brain Peptides 18 8 1997 1179 1187 (Pubitemid 28026887)