Potent Blockade of Hepatocyte Growth Factor-stimulated Cell Motility, Matrix Invasion and Branching Morphogenesis by Antagonists of Grb2 Src Homology 2 Domain Interactions

Journal of Biological Chemistry

Volumn 276, Issue 17, 2001, Pages 14308-14314

  Atabey, Nese ^a   Gao, Yang ^a   Yao, Zhu Jun ^a   Breckenridge, Diane ^a   Soon, Lilian ^a   Soriano, Jesus V ^a   Burke Jr , Terrence R ^a   Bottaro, Donald P ^a,b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b ENTREMED INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG PRODUCTS; PROTEINS; TISSUE; TUMORS;

MITOGENESIS;

CELLS;

COMPLEMENTARY DNA; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; SCATTER FACTOR; COLLAGEN; GRB2 PROTEIN, HUMAN; PROTEIN; SCATTER FACTOR RECEPTOR; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ARTICLE; CELL MIGRATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; EPITHELIUM CELL; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MITOGENESIS; MORPHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CELL MOTION; CHEMISTRY; DOG; DOSE RESPONSE; DRUG ANTAGONISM; GENETIC TRANSFECTION; GENETICS; IMMUNOBLOTTING; METABOLISM; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE; SERODIAGNOSIS; SRC HOMOLOGY DOMAIN; TIME;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; CELL MOVEMENT; COLLAGEN; DNA, COMPLEMENTARY; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR MATRIX; GRB2 ADAPTOR PROTEIN; HEPATOCYTE GROWTH FACTOR; HUMANS; IMMUNOBLOTTING; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN STRUCTURE, TERTIARY; PROTEINS; PROTO-ONCOGENE PROTEINS C-MET; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; TIME FACTORS; TRANSFECTION;

EID: 0035957990     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010202200     Document Type: Article

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