-
2
-
-
0036352690
-
Review of the molecular and cellular mechanisms of action of glucocorticoids for use in asthma
-
Umland S.P., Schleimer R.P., Johnston S.L. Review of the molecular and cellular mechanisms of action of glucocorticoids for use in asthma. Pulm Pharmacol Ther 2002, 15:35-50.
-
(2002)
Pulm Pharmacol Ther
, vol.15
, pp. 35-50
-
-
Umland, S.P.1
Schleimer, R.P.2
Johnston, S.L.3
-
3
-
-
33744477341
-
How corticosteroids control inflammation: Quintiles Prize Lecture 2005
-
Barnes P.J. How corticosteroids control inflammation: Quintiles Prize Lecture 2005. Br J Pharmacol 2006, 148:245-254.
-
(2006)
Br J Pharmacol
, vol.148
, pp. 245-254
-
-
Barnes, P.J.1
-
4
-
-
20344379422
-
Anti-inflammatory effects of inhaled corticosteroids in chronic obstructive pulmonary disease: similarities and differences to asthma
-
Jeffery P. Anti-inflammatory effects of inhaled corticosteroids in chronic obstructive pulmonary disease: similarities and differences to asthma. Expert Opin Invest Drugs 2005, 14:619-632.
-
(2005)
Expert Opin Invest Drugs
, vol.14
, pp. 619-632
-
-
Jeffery, P.1
-
5
-
-
0141497509
-
How do corticosteroids work in asthma?
-
Barnes P.J., Adcock I.M. How do corticosteroids work in asthma?. Ann Intern Med 2003, 139:359-370.
-
(2003)
Ann Intern Med
, vol.139
, pp. 359-370
-
-
Barnes, P.J.1
Adcock, I.M.2
-
6
-
-
26944455640
-
Effects of inhaled corticosteroids on pathology in asthma and chronic obstructive pulmonary disease
-
Chanez P., Bourdin A., Vachier I., Godard P., Bousquet J., Vignola A.M. Effects of inhaled corticosteroids on pathology in asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 2004, 1:184-190.
-
(2004)
Proc Am Thorac Soc
, vol.1
, pp. 184-190
-
-
Chanez, P.1
Bourdin, A.2
Vachier, I.3
Godard, P.4
Bousquet, J.5
Vignola, A.M.6
-
7
-
-
0037338904
-
The role of T lymphocytes in the pathogenesis of asthma
-
Larche M., Robinson D.S., Kay A.B. The role of T lymphocytes in the pathogenesis of asthma. J Allergy Clin Immunol 2003, 111:450-463.
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 450-463
-
-
Larche, M.1
Robinson, D.S.2
Kay, A.B.3
-
8
-
-
0029055474
-
Effects of " systemic" budesonide concentrations on in vitro allergen-induced activation of blood mononuclear cells isolated from asthmatic patients
-
Oddera S., Silvestri M., Sacco O., Scarso L., Lantero S., Quaglia R., et al. Effects of " systemic" budesonide concentrations on in vitro allergen-induced activation of blood mononuclear cells isolated from asthmatic patients. Allergy 1995, 50:397-404.
-
(1995)
Allergy
, vol.50
, pp. 397-404
-
-
Oddera, S.1
Silvestri, M.2
Sacco, O.3
Scarso, L.4
Lantero, S.5
Quaglia, R.6
-
9
-
-
0029943913
-
Eosinophil locomotion and the release of IL-3 and IL-5 by allergen stimulated mononuclear cells are effectively downregulated " in vitro" by budesonide
-
Lantero S., Sacco O., Scala C., Spallarossa D., Rossi D.G.A. Eosinophil locomotion and the release of IL-3 and IL-5 by allergen stimulated mononuclear cells are effectively downregulated " in vitro" by budesonide. Clin Exp Allergy 1996, 26:656-664.
-
(1996)
Clin Exp Allergy
, vol.26
, pp. 656-664
-
-
Lantero, S.1
Sacco, O.2
Scala, C.3
Spallarossa, D.4
Rossi, D.G.A.5
-
10
-
-
0035131348
-
The topical glucocorticoids beclomethasone dipropionate and fluticasone propionate inhibit human T-cell allergen-induced production of IL-5, IL-3 and GM-CSF mRNA and protein
-
Powell N., Till S.J., Kay A.B., Corrigan C.J. The topical glucocorticoids beclomethasone dipropionate and fluticasone propionate inhibit human T-cell allergen-induced production of IL-5, IL-3 and GM-CSF mRNA and protein. Clin Exp Allergy 2001, 31:69-76.
-
(2001)
Clin Exp Allergy
, vol.31
, pp. 69-76
-
-
Powell, N.1
Till, S.J.2
Kay, A.B.3
Corrigan, C.J.4
-
11
-
-
21844445109
-
Interleukin-10-secreting " regulatory" T cells induced by glucocorticoids and beta2-agonists
-
Peek E.J., Richards D.F., Faith A., Lavender P., Lee T.H., Corrigan C.J., et al. Interleukin-10-secreting " regulatory" T cells induced by glucocorticoids and beta2-agonists. Am J Respir Cell Mol Biol 2005, 33:105-111.
-
(2005)
Am J Respir Cell Mol Biol
, vol.33
, pp. 105-111
-
-
Peek, E.J.1
Richards, D.F.2
Faith, A.3
Lavender, P.4
Lee, T.H.5
Corrigan, C.J.6
-
12
-
-
0031802893
-
Glucocorticoids inhibit proliferation and interleukin-4 and interleukin-5 secretion by aeroallergen-specific T-helper type 2 cell lines
-
Crocker I.C., Church M.K., Newton S., Townley R.G. Glucocorticoids inhibit proliferation and interleukin-4 and interleukin-5 secretion by aeroallergen-specific T-helper type 2 cell lines. Ann Allergy Asthma Immunol 1998, 80:509-516.
-
(1998)
Ann Allergy Asthma Immunol
, vol.80
, pp. 509-516
-
-
Crocker, I.C.1
Church, M.K.2
Newton, S.3
Townley, R.G.4
-
13
-
-
84855927291
-
-
Global strategy for asthma management and prevention, updated Available on the GINA website
-
Global strategy for asthma management and prevention, updated 2009. Available on the GINA website: http://www.ginasthma.org/.
-
(2009)
-
-
-
14
-
-
33750450043
-
Safety of inhaled corticosteroids: room for improvement
-
Rossi G.A., Cerasoli F., Cazzola M. Safety of inhaled corticosteroids: room for improvement. Pulm Pharmacol Ther 2007, 20:23-35.
-
(2007)
Pulm Pharmacol Ther
, vol.20
, pp. 23-35
-
-
Rossi, G.A.1
Cerasoli, F.2
Cazzola, M.3
-
15
-
-
66949133866
-
Clinical pharmacokinetic and pharmacodynamic profile of inhaled ciclesonide
-
Nave R. Clinical pharmacokinetic and pharmacodynamic profile of inhaled ciclesonide. Clin Pharmacokinet 2009, 48:243-252.
-
(2009)
Clin Pharmacokinet
, vol.48
, pp. 243-252
-
-
Nave, R.1
-
16
-
-
33644987512
-
Cytokine-activated bronchial epithelial cell pro-inflammatory functions are effectively downregulated in vitro by ciclesonide
-
Silvestri M., Serpero L., Petecchia L., Sabatini F., Cerasoli F., Rossi G.A. Cytokine-activated bronchial epithelial cell pro-inflammatory functions are effectively downregulated in vitro by ciclesonide. Pulm Pharmacol Ther 2006, 19:210-217.
-
(2006)
Pulm Pharmacol Ther
, vol.19
, pp. 210-217
-
-
Silvestri, M.1
Serpero, L.2
Petecchia, L.3
Sabatini, F.4
Cerasoli, F.5
Rossi, G.A.6
-
17
-
-
34548203188
-
Modulation of human lung fibroblast functions by ciclesonide: evidence for its conversion into the active metabolite desisobutyryl-ciclesonide
-
Boero S., Sabatini F., Silvestri M., Petecchia L., Nachira A., Pezzolo A., et al. Modulation of human lung fibroblast functions by ciclesonide: evidence for its conversion into the active metabolite desisobutyryl-ciclesonide. Immunol Lett 2007, 112:39-46.
-
(2007)
Immunol Lett
, vol.112
, pp. 39-46
-
-
Boero, S.1
Sabatini, F.2
Silvestri, M.3
Petecchia, L.4
Nachira, A.5
Pezzolo, A.6
-
19
-
-
0029030494
-
Toxoplasma gondii-specific CD4+ T-cell clones from healthy, latently infected humans display a Th0 profile of cytokine secretion
-
Prigione I., Facchetti P., Ghiotto F., Tasso P., Pistoia V. Toxoplasma gondii-specific CD4+ T-cell clones from healthy, latently infected humans display a Th0 profile of cytokine secretion. Eur J Immunol 1995, 25:1298-1305.
-
(1995)
Eur J Immunol
, vol.25
, pp. 1298-1305
-
-
Prigione, I.1
Facchetti, P.2
Ghiotto, F.3
Tasso, P.4
Pistoia, V.5
-
20
-
-
35748979427
-
Ciclesonide uptake and metabolism in human alveolar type II epithelial cells (A549)
-
Nonaka T., Nave R., McCracken N., Kawashimo A., Katsuura Y. Ciclesonide uptake and metabolism in human alveolar type II epithelial cells (A549). BMC Pharmacol 2007, 7:12.
-
(2007)
BMC Pharmacol
, vol.7
, pp. 12
-
-
Nonaka, T.1
Nave, R.2
McCracken, N.3
Kawashimo, A.4
Katsuura, Y.5
-
21
-
-
34047160413
-
The role of esterases in the metabolism of ciclesonide to desisobutyryl-ciclesonide in human tissue
-
Mutch E., Nave R., McCracken N., Zech K., Williams F.M. The role of esterases in the metabolism of ciclesonide to desisobutyryl-ciclesonide in human tissue. Biochem Pharmacol 2007, 73:1657-1664.
-
(2007)
Biochem Pharmacol
, vol.73
, pp. 1657-1664
-
-
Mutch, E.1
Nave, R.2
McCracken, N.3
Zech, K.4
Williams, F.M.5
-
22
-
-
0028207569
-
Non-specific steroidal esterase activity and distribution in human and other mammalian tissues
-
Lund-Pero M., Jeppson B., Arneklo-Nobin B., Sjögren H.O., Holmgren K., Pero R.W. Non-specific steroidal esterase activity and distribution in human and other mammalian tissues. Clin Chim Acta 1994, 224:9-20.
-
(1994)
Clin Chim Acta
, vol.224
, pp. 9-20
-
-
Lund-Pero, M.1
Jeppson, B.2
Arneklo-Nobin, B.3
Sjögren, H.O.4
Holmgren, K.5
Pero, R.W.6
-
23
-
-
1642340164
-
In vitro and in vivo anti-inflammatory activity of the new glucocorticoid ciclesonide
-
Stoeck M., Riedel R., Hochhaus G., Hafner D., Masso J.M., Schmidt B., et al. In vitro and in vivo anti-inflammatory activity of the new glucocorticoid ciclesonide. J Pharmacol Exp Ther 2004, 309:249-258.
-
(2004)
J Pharmacol Exp Ther
, vol.309
, pp. 249-258
-
-
Stoeck, M.1
Riedel, R.2
Hochhaus, G.3
Hafner, D.4
Masso, J.M.5
Schmidt, B.6
-
24
-
-
33644834415
-
Increased glucocorticoid receptor beta alters steroid response in glucocorticoid insensitive asthma
-
Goleva E., Li L.B., Eves P.T., Strand M.J., Martin R.J., Leung D.Y. Increased glucocorticoid receptor beta alters steroid response in glucocorticoid insensitive asthma. Am J Respir Crit Care Med 2005, 173:607-616.
-
(2005)
Am J Respir Crit Care Med
, vol.173
, pp. 607-616
-
-
Goleva, E.1
Li, L.B.2
Eves, P.T.3
Strand, M.J.4
Martin, R.J.5
Leung, D.Y.6
-
25
-
-
33748744628
-
Structure, function and regulation of carboxylesterases
-
Satoh T., Hosokawa M. Structure, function and regulation of carboxylesterases. Chem Biol Interact 2006, 162:195-211.
-
(2006)
Chem Biol Interact
, vol.162
, pp. 195-211
-
-
Satoh, T.1
Hosokawa, M.2
-
26
-
-
33744467048
-
In vitro metabolism of ciclesonide in human lung and liver precision-cut tissue slices
-
Nave R., Fisher R., Zech K. In vitro metabolism of ciclesonide in human lung and liver precision-cut tissue slices. Biopharm Drug Dispos 2006, 27:197-207.
-
(2006)
Biopharm Drug Dispos
, vol.27
, pp. 197-207
-
-
Nave, R.1
Fisher, R.2
Zech, K.3
-
27
-
-
66949159685
-
Metabolism of ciclesonide in the upper and lower airways, review of available data
-
Nave R., McCracken N. Metabolism of ciclesonide in the upper and lower airways, review of available data. J Asthma Allergy 2008, 1:1-18.
-
(2008)
J Asthma Allergy
, vol.1
, pp. 1-18
-
-
Nave, R.1
McCracken, N.2
-
28
-
-
0028289245
-
The effect of dexamethasone, cyclosporine, and rapamycin on T-lymphocyte proliferation in vitro: comparison of cells from patients with glucocorticoid-sensitive and glucocorticoid-resistant chronic asthma
-
Haczku A., Alexander A., Brown P., Assoufi B., Li B., Kay A.B., et al. The effect of dexamethasone, cyclosporine, and rapamycin on T-lymphocyte proliferation in vitro: comparison of cells from patients with glucocorticoid-sensitive and glucocorticoid-resistant chronic asthma. J Allergy Clin Immunol 1994, 93:510-519.
-
(1994)
J Allergy Clin Immunol
, vol.93
, pp. 510-519
-
-
Haczku, A.1
Alexander, A.2
Brown, P.3
Assoufi, B.4
Li, B.5
Kay, A.B.6
-
29
-
-
0023118617
-
Interleukin 2 synthesis in the presence of steroids: a model of steroid resistance
-
Walker K.B., Potter J.M., House A.K. Interleukin 2 synthesis in the presence of steroids: a model of steroid resistance. Clin Exp Immunol 1987, 68:162-167.
-
(1987)
Clin Exp Immunol
, vol.68
, pp. 162-167
-
-
Walker, K.B.1
Potter, J.M.2
House, A.K.3
-
30
-
-
59149087048
-
IFN-gamma reverses IL-2- and IL-4-mediated T-cell steroid resistance
-
Goleva E., Li L.B., Leung D.Y. IFN-gamma reverses IL-2- and IL-4-mediated T-cell steroid resistance. Am J Respir Cell Mol Biol 2009, 40:223-230.
-
(2009)
Am J Respir Cell Mol Biol
, vol.40
, pp. 223-230
-
-
Goleva, E.1
Li, L.B.2
Leung, D.Y.3
-
31
-
-
0036231010
-
P38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma
-
Irusen E., Matthews J.G., Takahashi A., Barnes P.J., Chung K.F., Adcock I.M. p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma. J Allergy Clin Immunol 2002, 109:649-657.
-
(2002)
J Allergy Clin Immunol
, vol.109
, pp. 649-657
-
-
Irusen, E.1
Matthews, J.G.2
Takahashi, A.3
Barnes, P.J.4
Chung, K.F.5
Adcock, I.M.6
-
32
-
-
68549133480
-
Therapeutic targets for new therapy for corticosteroid refractory asthma
-
Ito K., Mercado N. Therapeutic targets for new therapy for corticosteroid refractory asthma. Expert Opin Ther Targets 2009, 13:1053-1067.
-
(2009)
Expert Opin Ther Targets
, vol.13
, pp. 1053-1067
-
-
Ito, K.1
Mercado, N.2
-
33
-
-
68949090382
-
The effects of cytokines on suppression of lymphocyte proliferation by dexamethasone
-
Creed T.J., Lee R.W., Newcomb P.V., di Mambro A.J., Raju M., Dayan C.M. The effects of cytokines on suppression of lymphocyte proliferation by dexamethasone. J Immunol 2009, 183:164-171.
-
(2009)
J Immunol
, vol.183
, pp. 164-171
-
-
Creed, T.J.1
Lee, R.W.2
Newcomb, P.V.3
di Mambro, A.J.4
Raju, M.5
Dayan, C.M.6
-
34
-
-
0029945783
-
Effect of natural allergen exposure during the grass pollen season on airways inflammatory cells and asthma symptoms
-
Djukanović R., Feather I., Gratziou C., Walls A., Peroni D., Bradding P., et al. Effect of natural allergen exposure during the grass pollen season on airways inflammatory cells and asthma symptoms. Thorax 1996, 51:575-581.
-
(1996)
Thorax
, vol.51
, pp. 575-581
-
-
Djukanović, R.1
Feather, I.2
Gratziou, C.3
Walls, A.4
Peroni, D.5
Bradding, P.6
-
35
-
-
78349301283
-
Deposition and metabolism of inhaled ciclesonide in the human lung
-
Nave R., Watz H., Hoffmann H., Boss H., Magnussen H. Deposition and metabolism of inhaled ciclesonide in the human lung. Eur Respir J 2010, 36:1113-1119.
-
(2010)
Eur Respir J
, vol.36
, pp. 1113-1119
-
-
Nave, R.1
Watz, H.2
Hoffmann, H.3
Boss, H.4
Magnussen, H.5
|