Modulation of human lung fibroblast functions by ciclesonide: Evidence for its conversion into the active metabolite desisobutyryl-ciclesonide

Immunology Letters

Volumn 112, Issue 1, 2007, Pages 39-46

  Boero, Silvia ^a   Sabatini, Federica ^a   Silvestri, Michela ^a   Petecchia, Loredana ^a   Nachira, Antonio ^a   Pezzolo, Annalisa ^a   Scarso, Lucia ^a   Rossi, Giovanni A ^a  

^a G GASLINI INSTITUTE   (Italy)

Author keywords

Adhesion molecule; Alpha smooth muscle actin; Chemokines; Corticosteroid; Myofibroblasts

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BASIC FIBROBLAST GROWTH FACTOR; CHEMOKINE; CICLESONIDE; DESISOBUTYRYL CICLESONIDE; DRUG METABOLITE; EOTAXIN; INTERCELLULAR ADHESION MOLECULE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; THYMIDINE; TRANSFORMING GROWTH FACTOR BETA1; TRITIUM; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; LUNG FIBROBLAST; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY TRACT INFLAMMATION; WESTERN BLOTTING;

ACTINS; ANTI-ASTHMATIC AGENTS; ANTI-INFLAMMATORY AGENTS; BIOTRANSFORMATION; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CHEMOKINE CCL2; CHEMOKINES, CC; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLAST GROWTH FACTOR 2; FIBROBLASTS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LUNG; PREGNENEDIONES; STRESS FIBERS; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34548203188     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2007.06.010     Document Type: Article

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