Employing the metabolic "branch point effect" to generate an all-or-none, digital-like response in enzymatic outputs and enzyme-based sensors

Analytical Chemistry

Volumn 84, Issue 2, 2012, Pages 1076-1082

  Rafael, Sandra Perez ^a   Vallée Bélisle, Alexis ^b   Fabregas, Esteve ^a   Plaxco, Kevin ^b   Palleschi, Giuseppe ^c,d   Ricci, Francesco ^c,d  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d NATIONAL INSTITUTE OF BIOSTRUCTURES AND BIOSYSTEMS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMPEROMETRIC; BRANCH POINTS; DOSE-RESPONSE CURVES; ENZYMATIC REACTION; ENZYME LOGIC; HEXOKINASES; HILL COEFFICIENT; METABOLIC NETWORK; MICHAELIS-MENTEN; MICHAELIS-MENTEN KINETIC; MODEL SYSTEM; MULTIMERIC; NATURALLY OCCURRING; NOISE ATTENUATION; REACTION CATALYZED; SUBSTRATE CONCENTRATIONS; SYNTHETIC BIOLOGY;

CATALYSIS; GLUCOSE; GLUCOSE OXIDASE; GLUCOSE SENSORS; METABOLISM; SENSORS;

ENZYME SENSORS;

GLUCOSE; GLUCOSE OXIDASE; HEXOKINASE; IMMOBILIZED ENZYME;

ARTICLE; CATALYSIS; ELECTRODE; GENETIC PROCEDURES; HUMAN; KINETICS; METABOLISM;

BIOSENSING TECHNIQUES; CATALYSIS; ELECTRODES; ENZYMES, IMMOBILIZED; GLUCOSE; GLUCOSE OXIDASE; HEXOKINASE; HUMANS; KINETICS;

EID: 84855941304     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac202701c     Document Type: Article

References (45)

1. Ro, D. K.; Paradise, E. M.; Quellet, M.; Fisher, K. J.; Newman, K. L.; Ndungu, J. M. Nature 2006, 440 (7086) 940-943
2. Koeller, K. M.; Wong, C. Nature 2001, 409 (6817) 232-240
3. Khalil, A. S.; Collins, J. J. Nature Rev. Genet. 2010, 1 (5) 367-379
4. Purnick, P. E. M.; Weiss, R. Nature Rev. Mol. Cell Biol. 2009, 10 (6) 410-422
5. Himmel, M. E.; Ding, S.; Johnson, D. K.; Adney, W. S.; Nimlos, M. R.; Brady, J. W. Science 2007, 315 (5813) 804-807
6. Wang, J. Electroanalysis 2001, 13 (12) 983-988
7. Wang, J. Chem. Rev. 2008, 108 (2) 814-825
8. Bakker, E. Anal. Chem. 2004, 76 (12) 3285-3598
9. DOrazio, P. Clin. Chim. Acta 2003, 334 (1-2) 41-69
10. Wang, J.; Katz, E. Anal. Bioanal. Chem. 2010, 398 (4) 1591-1603
11. Katz, E.; Privman, V. Chem. Soc. Rev. 2010, 39 (5) 1835-1857
12. Manesh, K. M.; Halámek, J.; Pita, M.; Zhou, J.; Tam, T. K.; Santhosh, P. Biosens. Bioelectron. 2009, 24 (12) 3569-3574
13. Windmiller, J. R.; Santhosh, P.; Katz, E.; Wang, J. Sensor Actuat. B-Chem. 2010, 10.1016
14. Ferrell, J. E., Jr. Trends Biochem. Sci. 1996, 21 (12) 460-466
15. Goldbeter, A.; Koshland, D. E., Jr. Q. Rev. Biophys. 1982, 15, 555-591
16. Privman, V.; Pedrosa, V.; Melnikov, D.; Pita, M.; Simonian, A.; Katz, E. Biosens. Bioelectron. 2009, 25 (4) 695
17. Privman, V.; Halámek, J.; Arugula, M. A.; Melnikov, D.; Bocharova, V.; Katz, E. J. Phys. Chem. B. 2010, 114 (44) 14103
18. Wang, J.; Katz, E. Isr. J. Chem. 2011, 51 (1) 141
19. Privman, V. Isr. J. Chem. 2011, 51 (1) 118
20. Doron, A.; Portnoy, M.; Lion-Dagan, M.; Katz, E.; Willner, I. J. Am. Chem. Soc. 1996, 118, 8937
21. Ashton, P. R.; Ballardini, R.; Balzani, V.; Credi, A.; Dress, K. R.; Ishow, E.; Kleverlaan, C. J.; Kocian, O.; Preece, J. A.; Spencer, N.; Stoddart, J. F.; Venturi, M.; Wenger, S. Chem. - Eur. J. 2000, 6, 3558
22. Pita, M.; Privman, V.; Arugula, M. A.; Melnikov, D.; Bocharova, V.; Katz, E. Phys. Chem. Chem. Phys. 2011, 13 (10) 4507
23. Halamek, J.; Zhou, J.; Halamkova, L.; Bocharova, V.; Privman, V.; Wang, J.; Katz, E. Anal. Chem. 2011, in press.
24. Goldbeter, A.; Koshland, D. E., Jr. J. Biol. Chem. 1984, 259, 14441-14447
25. Kim, S. Y.; Ferrell, J. E., Jr. Cell 2007, 128 (6) 1133-1145
26. LaPorte, D. C.; Walsh, K.; Koshland, D. E., Jr. J. Biol. Chem. 1984, 259 (22) 14068-14075
27. Legewie, S.; Blüthgen, N.; Schäfer, R.; Herzel, H. PLoS Comput. Biol. 2005, 1 (5) 0405-0414
28. Legewie, S.; Schoeberl, B.; Blüthgen, N.; Herzel, H. Biophys. J. 2007, 93 (7) 2279-2288
29. Ricci, F.; Amine, A.; Palleschi, G.; Moscone, D. Biosens. Bioelectron. 2003, 18 (2-3) 165-174
30. Ricci, F.; Palleschi, G. Biosens. Bioelectron. 2005, 21 (3) 389-407
31. Chaubey, A.; Malhotra, B. D. Biosens. Bioelectron. 2002, 17 (6-7) 441-456
32. Liu, H; Wang, Z; Liu, Y; Xiao, J; Wang, C. Thermochim. Acta 2006, 443 (2) 173
33. Wilson, J. E. J. Exp. Biol. 2003, 206 (12) 2049-2057
34. Hill, A. V. J. Physiol. 1910, 40, iv-vii
35. Niazov, T.; Baron, R.; Katz, E.; Lioubashevski, O.; Willner, I. Proc. Natl. Acad. Sci. U S A 2006, 103 (46) 17160-17163
36. Dwyer, M. A.; Hellinga, H. W. Curr. Opin. Struct. Biol. 2004, 14, 495-504
37. Gorman, M. W.; Feigl, E. O.; Buffington, C. W. Clin. Chem. 2007, 53 (2) 318
38. Bodin, P.; Burnstock, G. J. Cardiovasc. Pharmacol. 1996, 27 (6) 872
39. Ferrell, J. E., Jr. Curr. Biol. 2008, 18 (6) R244-245
40. Buchler, N. E.; Louis, M. J. Mol. Biol. 2008, 384 (5) 1106-1119
41. Buchler, N. E.; Cross, F. R. Mol. Syst. Biol. 2009, 5, 272
42. Novick, A.; Weiner, M. Proc. Natl. Acad. Sci. U.S.A. 1957, 43, 553-566
43. Monod, J.; Jacob, F. Cold Spring Harb. Symp. Quant. Biol. 1961, 26, 389-401
44. Griffith, J. S. J. Theor. Biol. 1968, 20 (2) 209-216
45. Ferrell, J. E., Jr. Curr. Opin. Cell Biol. 2002, 14 (2) 140-148