Rapid quantification of bile acids and their conjugates in serum by liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 30, 2009, Pages 3920-3925

  Scherer, Max ^a   Gnewuch, Carsten ^a   Schmitz, Gerd ^a   Liebisch, Gerhard ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Bile acid; Deuterated internal standard; Liquid chromatography tandem mass spectrometry (LC MS MS); Method validation; Quantification

Indexed keywords

ANALYSIS TIME; AS-LIGANDS; BASE LINE; BASELINE SEPARATION; BILE ACID; CALIBRATION LINES; CLINICAL STUDY; ENERGY METABOLISM; G-PROTEIN COUPLED RECEPTORS; GRADIENT ELUTION; HIGH SENSITIVITY; INTERNAL STANDARDS; LC-MS/MS; LIMITS OF DETECTION; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; METHOD VALIDATIONS; NUCLEAR HORMONE RECEPTOR; PROTEIN PRECIPITATION; REVERSED PHASE; RUNTIMES; SAMPLE PREPARATION; SENSITIVE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; SOLUBILIZERS; STANDARD ADDITION; STRUCTURAL DIVERSITY;

ACIDS; BIOCHEMISTRY; BODY FLUIDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; DEUTERIUM; FLUORINE CONTAINING POLYMERS; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLISM; PROTEINS; STANDARDS;

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

BILE ACID; CHENODEOXYCHOLIC ACID; CHOLIC ACID; DEOXYCHOLIC ACID; DEUTERIUM; GLYCOCHENODEOXYCHOLIC ACID; GLYCOCHOLIC ACID; GLYCODEOXYCHOLIC ACID; GLYCOHYODEOXYCHOLIC ACID; GLYCOLITHOCHOLIC ACID; GLYCOURSODEOXYCHOLIC ACID; HYODEOXYCHOLIC ACID; LITHOCHOLIC ACID; TAUROCHENODEOXYCHOLIC ACID; TAUROCHOLIC ACID; TAURODEOXYCHOLIC ACID; TAUROHYODEOXYCHOLIC ACID; TAUROLITHOCHOLIC ACID; TAUROURSODEOXYCHOLIC ACID; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID;

ARTICLE; BILE ACID BLOOD LEVEL; CALIBRATION; ELUTION; HUMAN; LIQUID CHROMATOGRAPHY; NORMAL HUMAN; PRECIPITATION; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SERUM; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

ADULT; BILE ACIDS AND SALTS; CHROMATOGRAPHY, LIQUID; FEMALE; HUMANS; MALE; MIDDLE AGED; TANDEM MASS SPECTROMETRY; YOUNG ADULT;

EID: 72049088292     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.09.038     Document Type: Article

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