PGC-1α induces mitochondrial and myokine transcriptional programs and lipid droplet and glycogen accumulation in cultured human skeletal muscle cells

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Mormeneo, Emma ^a,b   Jimenez Mallebrera, Cecilia ^c   Palomer, Xavier ^a,b   de Nigris, Valeria ^d   Vázquez Carrera, Manuel ^a,b   Orozco, Anna ^a,b   Nascimento, Andrés ^c   Colomer, Jaume ^c   Lerín, Carles ^a,d   Gómez Foix, Anna M ^a,b  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c HOSPITAL SANT JOAN DE DÉU   (Spain)

^d INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CALM1 PROTEIN; CYTOKINE; FAT DROPLET; GLUCOSE; GLYCOGEN; GLYCOGEN PHOSPHORYLASE; GRANULOCYTE CHEMOTACTIC PROTEIN 2; INTERLEUKIN 8; MESSENGER RNA; MITOCHONDRIAL PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 2; OLEIC ACID; OLIGONUCLEOTIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHORYLASE KINASE; PROSTAGLANDIN SYNTHASE; RANTES; TRANSCRIPTOME; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; CALMODULIN; CYTOCHROME C OXIDASE; FITM1 PROTEIN, HUMAN; HEAT SHOCK PROTEIN; LIPID; MEMBRANE PROTEIN; PARVALBUMIN; PPARGC1A PROTEIN, HUMAN; PPARGC1A PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; BIOACCUMULATION; CALCIUM SIGNALING; CHEMOTAXIS; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INACTIVATION; FATTY ACID METABOLISM; FITM1 GENE; GENE; GENE CONTROL; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; METABOLIC REGULATION; MICROARRAY ANALYSIS; MITOCHONDRIAL RESPIRATION; MUSCLE ATROPHY; MUSCLE CELL; MYOKINE GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROTEIN CONTENT; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN PROTEIN INTERACTION; PVALB GENE; SKELETAL MUSCLE CELL; UNINDEXED SEQUENCE; UPREGULATION; CELL CULTURE; CYTOLOGY; DNA MICROARRAY; GENETICS; METABOLISM; PRIMARY CELL CULTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; WESTERN BLOTTING;

BLOTTING, WESTERN; CALMODULIN; CELLS, CULTURED; CHEMOKINE CCL5; CHEMOKINE CCL8; CHEMOKINE CXCL6; CYTOKINES; ELECTRON TRANSPORT COMPLEX IV; GLYCOGEN; HEAT-SHOCK PROTEINS; HUMANS; INTERLEUKIN-8; LIPIDS; MEMBRANE PROTEINS; MITOCHONDRIAL PROTEINS; MUSCLE CELLS; MUSCLE, SKELETAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARVALBUMINS; PRIMARY CELL CULTURE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTOME; TRIGLYCERIDES;

EID: 84855857733     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029985     Document Type: Article

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