PGC-1α plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscle

American Journal of Physiology - Cell Physiology

Volumn 298, Issue 3, 2010, Pages

  Geng, Tuoyu ^a,c   Li, Ping ^a   Okutsu, Mitsuharu ^c   Yin, Xinhe ^a   Kwek, Jyeyi ^b   Zhang, Mei ^a,c   Yan, Zhen ^a,b,c  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Endurance exercise; Gene expression; Remodeling; Signal transduction

Indexed keywords

CD31 ANTIGEN; CYTOCHROME C; CYTOCHROME C OXIDASE; MANGANESE SUPEROXIDE DISMUTASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; MYOSIN; MYOSIN HEAVY CHAIN; PPARGC1A PROTEIN, MOUSE; SUPEROXIDE DISMUTASE; TRANSACTIVATOR PROTEIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; BIOGENESIS; CELL TRANSFORMATION; CONTROLLED STUDY; ENDOTHELIUM CELL; EXERCISE; KNOCKOUT MOUSE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SKELETAL MUSCLE; ADAPTATION; ANIMAL; ENDURANCE; ENZYMOLOGY; FAST MUSCLE FIBER; GENETICS; METABOLISM; MOUSE MUTANT; MUSCLE CONTRACTION; MUSCLE MITOCHONDRION; PATHOLOGY; PHENOTYPE; RUNNING; VASCULARIZATION;

MUS;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ANTIGENS, CD31; CYTOCHROMES C; ELECTRON TRANSPORT COMPLEX IV; ENDOTHELIAL CELLS; MICE; MICE, KNOCKOUT; MITOCHONDRIA, MUSCLE; MUSCLE CONTRACTION; MUSCLE FIBERS, FAST-TWITCH; MUSCLE, SKELETAL; MYOSIN HEAVY CHAINS; NEOVASCULARIZATION, PHYSIOLOGIC; PHENOTYPE; PHYSICAL ENDURANCE; RUNNING; SKELETAL MUSCLE MYOSINS; SUPEROXIDE DISMUTASE; TRANS-ACTIVATORS;

EID: 77749264581     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00481.2009     Document Type: Article

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