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Volumn 20, Issue 2, 2012, Pages 1046-1059

Pyrrolo- and pyrazolo-[3,4-e][1,2,4]triazolo[1,5-c]pyrimidines as adenosine receptor antagonists

(9) Baraldi, Pier Giovanni a Saponaro, Giulia a Aghazadeh Tabrizi, Mojgan a Baraldi, Stefania a Romagnoli, Romeo a Moorman, Allan R b Varani, Katia a Borea, Pier Andrea a Preti, Delia a

a UNIVERSITY OF FERRARA (Italy)

b King Pharmaceuticals Inc (United States)

Author keywords

Adenosine; Adenosine antagonists; Pyrazolo triazolo pyrimidines; Pyrrolo triazolo pyrimidines

Indexed keywords

1 METHYL 4 NITRO 1H PYRAZOLE 3 CARBOXAMIDE; 1 METHYL 4 NITRO 1H PYRAZOLE 5 CARBOXAMIDE; 1 PROPYL 4 NITRO 1H PYRAZOLE 3 CARBOXAMIDE; 1 PROPYL 4 NITRO 1H PYRAZOLE 5 CARBOXAMIDE; 1,3 DIBENZYL 6 (3 PHENYLPROPYL) 1,6 DIHYDROPYRROLO[3,4 D]PYRIMIDINE 2,4 DIONE; 1,3 DIBENZYL 6 ALKYL 1,6 DIHYDROPYRROLO[3,4 D]PYRIMIDINE; 1,3 DIBENZYL 6 METHYL 1,6 DIHYDROPYRROLO[3,4 D]PYRIMIDINE 2,4 DIONE; 1,3 DIBENZYL 6 PHENETHYL 1,6 DIHYDROPYRROLO[3,4 D]PYRIMIDINE 2,4 DIONE; 1,3 DIBENZYL 6 PROPYL 1,6 DIHYDROPYRROLO[3,4 D]PYRIMIDINE 2,4 DIONE; 4 AMINO 1 (2 PHENYLETHYL) 1H PYRAZOLE 3 CARBOXAMIDE; 4 AMINO 1 (2 PHENYLETHYL) 1H PYRAZOLE 5 CARBOXAMIDE; 4 AMINO 1 (2 PHENYPROPYL) 1H PYRAZOLE 3 CARBOXAMIDE; 4 AMINO 1 (2 PHENYPROPYL) 1H PYRAZOLE 5 CARBOXAMIDE; 4 AMINO 1 (3 PHENYPROPYL) 1H PYRAZOLE 5 CARBOXAMIDE; 4 AMINO 1 ALKYL 1H PYRAZOLE 3 CARBOXAMIDE; 4 AMINO 1 ALKYL 1H PYRAZOLE 5 CARBOXAMIDE; 4 AMINO 1 METHYL 1H PYRAZOLE 3 CARBOXAMIDE; 4 AMINO 1 METHYL 1H PYRAZOLE 5 CARBOXAMIDE; 4 AMINO 1 PROPYL 1H PYRAZOLE 3 CARBOXAMIDE; 4 AMINO 1 PROPYL 1H PYRAZOLE 5 CARBOXAMIDE; 4 NITRO 1 (2 PHENYLETHYL) 1H PYRAZOLE 3 CARBOXAMIDE; 4 NITRO 1 (2 PHENYLETHYL) 1H PYRAZOLE 5 CARBOXAMIDE; 6 (3 PHENYLPROPYL) 1,6 DIHYDROPYRROLO[3,4 D]PYRIMIDINE 2,4 DIONE; 6 METHYL 1,6 DIHYDROPYRROLO[3,4 D]PYRIMIDINE 2,4 DIONE; 6 PHENETHYL 1,6 DIHYDROPYRROLO[3,4 D]PYRIMIDINE 2,4 DIONE; 6 PROPYL 1,6 DIHYDROPYRROLO[3,4 D]PYRIMIDINE 2,4 DIONE; ADENOSINE RECEPTOR BLOCKING AGENT; PYRAZOLO[3,4 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE DERIVATIVE; PYRROLO[3,4 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; ISOMERISM; STRUCTURE ACTIVITY RELATION;

HUMANS; PROTEIN BINDING; PURINERGIC P1 RECEPTOR ANTAGONISTS; PYRAZOLES; PYRIMIDINES; RECEPTOR, ADENOSINE A2A; RECEPTOR, ADENOSINE A3; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

HUMAN ECHOVIRUS 1;

EID: 84855817557 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2011.11.037 Document Type: Article

Times cited : (35)

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