An expeditious synthesis of pyrrolo[3, 4-d]-pyrimidine -2, 4-dione from uracil

Heterocycles

Volumn 53, Issue 1, 2000, Pages 205-211

  Zimmerman, Michael N ^a   Nemeroff, Norman H ^a   Bock, Charles W ^a   Bhat, Krishna L ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOCYANIC ACID DERIVATIVE; PYRROLE DERIVATIVE; PYRROLO[3,4 D]PYRIMIDINE 2,4 DIONE; PYRROLOPYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; URACIL;

ARTICLE; CALCULATION; CHEMICAL REACTION; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; STRUCTURE ANALYSIS;

EID: 0033973045     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-99-8732     Document Type: Article

References (13)

1. A.J. Elliott, P. E. Morris, Jr., S. L. Petty, and C. H. Williams, J. Org. Chem., 1997, 62, 8071 and references cited therein.
2. W.F. Michne, J. D. Schroeder, J. W. Guiles, A. M. Treasurywala, C. A. Weigelt, M. F. Stansberry, E. McAvoy, C. R. Shah, Y. Baine, D. G. Sawutz, P. B. Miller, B. M. Stankunas, J. Reid, E. Bump, and D. Schlegel, J. Med. Chem., 1995, 38, 2557.
3. N.G. Kundu, S. Sikdar, R. P. Hertzberg, S. A. Schmilz, and S. G. Khatri, J. Client. Soc., Perkin Trans, l, 1985, 1295 and references cited therein.
4. P. Frandjean, R. Benhaddou, R. Granet, and P. Krausz, Tetrahedron Lett., 1997, 38, 6185.
5. L. Arias, A. Guzman, S. Jaime-Figueroa, F. J. Lopez, D. J. Morgans, Jr., F. Padilla, A. PerezMedrano, C. Quintero, M. Romero, and L. Sandoval, Syn Lett., 1998, 1233.
6. Spartan Version 5.0, Wavefunction, Inc., 18401, Von Korman Avenue, Suite 370, Irvine, CA 92610, U.S.A.
7. A.M. Van Leusen, H. Sideriou, B. E. Hoogenboom, and T. D. Van Leusen, Tetrahedron Lett., 1972, 5337; D. Van Leusen, E. V. Echten, and A. M. Van Leusen, J. Org. Chem., 1992, 57, 2245; H. P. Dijkstra, R. T. Have, and A. M. Van lausen, J. Org. Chem., 1998, 63, 5332.
8. C.Y. DeLeon and B. Ganem, J. Org. Chem., 1996, 61, 8730; N. P. Pavri and M. L. Trudell, J. Org. Chem., 1997, 62, 2649; T. J. Donohoe, P. M. Guyo, R. R. Harji, M. Helliwell, and R. P. C. Cousins, Tetrahedron Lett., 1998, 39, 3075.
9. K.C. Majumdar, U. Das, and N. K. Jana, J. Org. Chem., 1998, 63, 3550.
10. M.J.S. Dewar, E. G. Zoebisch, and E. F. Healy, J. Am. Chem. Soc., 1985, 107, 3902.
11. N.G. Kundu, R. P. Hertzberg, and S. J. Hannon, Tetrahedron Lett., 1980, 21, 1109.
12. M. Botta, V. Summa, R. Saladino, and R. Nicoletti, Syn. Comm., 1991, 21, 2181.
13. A.D. Becke, Phys. Rev A., 1988, 38, 3098; J. P. Perdew and A. Zunger, Phys. RevB., 1981, 23, 5048.