Effects of silymarin and formulation on the oral bioavailability of paclitaxel in rats

European Journal of Pharmaceutical Sciences

Volumn 45, Issue 3, 2012, Pages 296-301

  Park, Joon Hee ^a   Park, Jung Hyun ^a   Hur, Hye Jung ^a   Woo, Jong Soo ^b   Lee, Hwa Jeong ^a  

^a Ewha Womans University   (South Korea)

^b Hanmi Pharmaceutical Co Ltd   (South Korea)

Author keywords

Bioavailability; Microemulsion; Paclitaxel; Pharmacokinetics; Silymarin

Indexed keywords

PACLITAXEL; SILYMARIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG FORMULATION; DRUG POTENTIATION; MALE; MAXIMUM PLASMA CONCENTRATION; MICROEMULSION; NONHUMAN; PRIORITY JOURNAL; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; EMULSIONS; HUMANS; INTESTINAL ABSORPTION; MALE; P-GLYCOPROTEIN; PACLITAXEL; RATS; RATS, SPRAGUE-DAWLEY; SILYMARIN;

EID: 84855800458     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2011.11.021     Document Type: Article

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