Improvement of the dissolution rate of silymarin by means of solid dispersions

Chemical and Pharmaceutical Bulletin

Volumn 52, Issue 8, 2004, Pages 972-973

  Li, Feng Qian ^a   Hu, Jin Hong ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Dissolution; Polyethylene glycol 6000; Silymarin; Solid dispersion

Indexed keywords

MACROGOL 6000; POLYMER; SILYMARIN; MACROGOL DERIVATIVE; WATER;

ARTICLE; DISPERSION; DRUG ABSORPTION; DRUG FORMULATION; DRUG SOLUBILITY; IN VITRO STUDY; MOUTH MUCOSA; SOLID; ABSORPTION; CHEMISTRY; SOLUBILITY; TIME;

ABSORPTION; CHEMISTRY, PHARMACEUTICAL; POLYETHYLENE GLYCOLS; SILYMARIN; SOLUBILITY; TIME FACTORS; WATER;

EID: 16644371829     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.52.972     Document Type: Article

References (8)

1. Sun T. M., Li X., Chin. Tradit. Herb. Drugs, 31, 229-231 (2000).
2. Yu L. C., Gu C. H., Chin. Hosp. Pharm. J., 21, 493-494 (2001).
3. Kai T., Akiyama Y., Nomura S., Sato M., Chem. Pharm. Bull., 44, 568-571 (1996).
4. Craig D. Q. M., Int. J. Pharmaceut., 231, 131-144 (2002).
5. Li F. Q., Hu J. H., Zhu Q. G., Chin. Tradit. Herb. Drugs, 33, 31-33 (2002).
6. Higuchi T., Connors K. A., Adv. Anal. Chem. Instrum., 4, 117-210 (1965).
7. Serajuddin A. T. M., Sheen P. C., Augustine M. A., J. Pharm. Sci., 79, 463-464 (1990).
8. Li F. Q., Hu J. H., Wang H., Zhu Q. G., Sun H. J., Cai Z., Acta Pharmaceut. Sin., 37, 294-298 (2002).