Genetic engineering of Ketogulonigenium vulgare for enhanced production of 2-keto-l-gulonic acid

Journal of Biotechnology

Volumn 157, Issue 2, 2012, Pages 320-325

  Cai, Lei ^a   Yuan, Mei Qing ^b   Li, Zheng Jun ^c   Chen, Jin Chun ^a   Chen, Guo Qiang ^a  

^a PEKING UNIVERSITY   (China)

^b INSTITUTE OF FORENSIC SCIENCE   (China)

^c BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

Author keywords

2 Keto l gulonic acid; Folate; Ketogulonigenium vulgare; Synthetic biology; Vitamin C

Indexed keywords

2-KETO-L-GULONIC ACID (2-KGA); BACILLUS MEGATERIUM; BIOSYNTHESIS GENES; CELL DENSITY; FERMENTORS; FOLATE; GENE CLUSTERS; GROWTH FACTOR; INDUSTRIAL PRODUCTION; KETOGULONIGENIUM VULGARE; L-ASCORBIC ACID; LACTOCOCCUS LACTIS; METABOLIC ENGINEERING; MIXED CULTURES; RECOMBINANT STRAINS; SHAKE FLASKS; SYNTHETIC BIOLOGY; VITAMIN C; WILD TYPES;

BACTERIOLOGY; BIOCHEMISTRY; BIOSYNTHESIS; CELL CULTURE; GENETIC ENGINEERING; KETONES; ORGANIC ACIDS; VITAMINS;

GENES;

2 OXOGULONIC ACID; FOLIC ACID; SORBOSE; SUGAR ACID; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; BACTERIUM; BIOREACTOR; BIOSYNTHESIS; CELL DENSITY; CONTROLLED STUDY; FOLB GENE; FOLC GENE; FOLKE GENE; FOLP GENE; GENE; GENE CLUSTER; GENE OVEREXPRESSION; GENETIC ENGINEERING; HUMAN; INDUSTRIAL PRODUCTION; KETOGULONIGENIUM VULGARE; LACTOCOCCUS LACTIS; NONHUMAN; PH; PRIORITY JOURNAL; PROMOTER REGION; WILD TYPE;

ASCORBIC ACID; BACILLUS MEGATERIUM; BIOREACTORS; FERMENTATION; FOLIC ACID; INDUSTRIAL MICROBIOLOGY; LACTOCOCCUS LACTIS; METABOLIC ENGINEERING; RHODOBACTERACEAE; SUGAR ACIDS; TRANSGENES;

BACILLUS MEGATERIUM; KETOGULONICIGENIUM VULGARE; LACTOCOCCUS LACTIS;

EID: 84855700444     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2011.12.004     Document Type: Article

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