Structural modification of ginsenoside Rh 2 by fatty acid esterification and its detoxification property in antitumor

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 2, 2012, Pages 1082-1085

  Wei, Gong Qing ^a   Zheng, Yi Nan ^a   Li, Wei ^a   Liu, Wen Cong ^a   Lin, Ting ^b   Zhang, Wei Yun ^b   Chen, Hai Feng ^b   Zeng, Jin Zhang ^b   Zhang, Xiao Kun ^b   Chen, Quan Cheng ^b  

^a JILIN AGRICULTURAL UNIVERSITY   (China)

^b XIAMEN UNIVERSITY   (China)

Author keywords

12,6 Dioctanoyl ginsenoside Rh 2; Antitumor; Detoxification; Structural modification

Indexed keywords

12,6' DIOCTANOYL GINSENOSIDE RH2; ANTINEOPLASTIC AGENT; FATTY ACID; GINSENOSIDE RH 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DETOXIFICATION; DRUG STRUCTURE; ESTERIFICATION; HUMAN; HUMAN CELL; LIVER CANCER; MOUSE; NONHUMAN; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTERS; FATTY ACIDS; GINSENOSIDES; HUMANS; MICE; MICE, INBRED STRAINS; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; SPLEEN; STRUCTURE-ACTIVITY RELATIONSHIP; THYMUS GLAND; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS; PANAX GINSENG;

EID: 84855697800     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.11.104     Document Type: Article

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